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Anxiety & Mood Disorder Program


The Anxiety and Mood Disorders Program uses a range of assessment approaches, several developed by members of our team, including self-reports, behavioral assessments, EEG technology, and fMRI imaging. Currently, we are conducting two large clinical trials: One is testing the effects of a brief computer-based training that targets attentional processes to reduce social anxiety in children, and uses EEG to study the effects of the treatment on the child’s brain.

The second is examining the effects of parent-based treatment for reducing childhood anxiety, and uses fMRI to study the effects of the treatment on the child’s brain.

The Anxiety and Mood Disorders Program is active in a number of collaborative projects inside and outside Yale. Projects aim to advance understanding of neurobiological mechanisms that underlie anxiety and mood disorders including the role of parents, developing and testing novel methods to enhance current evidence-based treatments, and delineating mechanisms associated with prevention, maintenance, and treatment of anxiety and co-occurring problems.

The Anxiety and Mood Disorders Program is led by Wendy Silverman, PhD, Alfred A. Messer Professor of Child Psychiatry and Director of the Yale Child Study Center Program’s Anxiety and Mood Disorders Program, and Eli Lebowitz, PhD, Associate Professor in the Child Study Center and Associate Director of the Anxiety and Mood Disorders Program.

Participant Eligibility/Benefits

  • Children and adolescents ages 6 to 14 years
  • Families receive assessment and treatment at no cost
  • Participant compensation up to $600

Research Interest

Assessment and treatment of anxiety and related disorders in youth, and the neurobiology and psychology of parenting anxious children.

Primary IRB Study Titles

  • Targeting Attention Orienting to Social Threat to Reduce Social anxiety in Youth (HIC# 2000025143)
  • Brain Response Associated with Parent-Based Treatment for Childhood Anxiety Disorders (HIC# 2000023649)
  • Measures of Anxiety Related Variables in the General Population (HIC# 1506016058)
  • Sociodemographic and Clinical Characteristics of Anxiety and Related Disorders (HIC# 1306012298)
  • P1 as a Biomarker of Attention to Social Threat (HIC #2000029999)

Secondary IRB Study Titles

  • SPACE-FTL (Failure to Launch): IRB 2000029082
  • Development of a Parent Training Intervention for Pediatric Patients with Medically Unexplained Symptoms: IRB 2000027265

Research Team