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Le Zhang, PhD

Assistant Professor

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Le Zhang, PhD


Le Zhang is an Assistant Professor in the Department of Neurology at Yale School of Medicine. Dr. Zhang’s research focuses on the immune responses of the central nervous system in neurodegenerative diseases, including Parkinson’s disease, Alzheimer’s disease, HIV-associated dementia, and Multiple sclerosis, using cutting-edge single cell technologies.

Dr. Zhang obtained her B.S. in Biological Science from Peking University in 2004 and her Ph.D. in Molecular Biology and Biochemistry from the University of Hong Kong in 2010, where she studied epigenetic regulation in aging and senescence with Dr. Zhongjun Zhou. Dr. Zhang continued her training in epigenetics as a postdoctoral fellow in the laboratory of Dr. Zhaolan Zhou at the University of Pennsylvania School of Medicine in the field of neuroscience and as a research fellow with Dr. Jordan Kreidberg at Harvard Medical School in the area of development. After a short journey at Pfizer in the R&D of neuroscience, Dr. Zhang joined Yale School of Medicine as Associate Research Scientist, leading single cell research in neurological disorders, and started her current position as Assistant Professor in the Department of Neurology in 2020.

Education & Training

  • Research Fellow
    Harvard Medical School (2016)
  • Postdoctoral Fellow
    University of Pennsylvania School of Medicine (2011)
  • PhD
    The University of Hong Kong (2010)
  • BS
    Peking University (2004)

Honors & Recognition

Yale Alzheimer's Disease Research Center (ADRC) Research Scholar Award2021
Women’s Health Research at Yale Pilot Project Award2020
Yale Alzheimer’s Disease Research Center Pilot Project Award2019
Kavli Institute for Neuroscience Innovative Research Award2019
Yale Center for Genome Analysis Pilot Research2018
Keystone Symposia Scholarship2009

Professional Service

Yale University School of Medicine Faculty Advisory CouncilRepresentative2018 - Present

Departments & Organizations