Yanis Chemli, PhD
Postdoctoral AssociateAbout
Research
Publications
2025
Impact of Depth-of-Interaction and Spatially-Variant Point-Spread-Function Model on the Performance of Ultra-High Resolution Brain PET
Zeng T, Najmaoui Y, Zhang J, Fontaine K, Hu Y, Chemli Y, Gallezot J, Sun C, Lu Y, Fakhri G, Carson R, Marin T. Impact of Depth-of-Interaction and Spatially-Variant Point-Spread-Function Model on the Performance of Ultra-High Resolution Brain PET. 2021 IEEE Nuclear Science Symposium And Medical Imaging Conference (NSS/MIC) 2025, 1-2. DOI: 10.1109/nss/mic/rtsd57106.2025.11287015.Peer-Reviewed Original ResearchSpatially-varying point spread functionPoint spread functionAccurate point spread functionPSF modelConvergence behaviorImage qualityPoint spread function modelReconstruction toolboxPSF parametersHigh-activity regionsBrain-dedicated PET scannersDepth of interactionPoint-spread-function modelingField of viewSpatial resolutionHuman scansContrast recoverySpread functionPET systemPET scannerReal phantomBrain phantomMonte Carlo simulationsBrain positron emission tomographyCarlo simulationsPhysics-Informed List-Mode Deep Image Prior Reconstruction with Motion Correction in 3D Brain PET
Chemli Y, Najmaoui Y, Normandin M, Fakhri G, Marin T, Ouyang J. Physics-Informed List-Mode Deep Image Prior Reconstruction with Motion Correction in 3D Brain PET. 2021 IEEE Nuclear Science Symposium And Medical Imaging Conference (NSS/MIC) 2025, 1-2. DOI: 10.1109/nss/mic/rtsd57106.2025.11287851.Peer-Reviewed Original ResearchDeep Image PriorList-modeContrast recoveryMotion correctionList-mode eventsReconstructed activity distributionHoffman brain phantomNoise-resolution trade-offML-EM reconstructionLow-count dataResolution phantomBrain phantomBrain positron emission tomographySuper-resolution effectActivity distributionModel attenuationML-EMBack-projection operationsFine structureDown-sampled dataNegative log-likelihoodImage registrationUnsupervised regularizerBack-projectionImage priorsYRT-PET-NX: Development of a Plugin for an Open-Source PET Reconstruction Platform to Support the NeuroEXPLORER
Najmaoui Y, Fontaine K, Fontaine D, Zhang J, Zeng T, Volpi T, Chemli Y, Gallezot J, Tétrault M, Carson R, Fakhri G, Marin T. YRT-PET-NX: Development of a Plugin for an Open-Source PET Reconstruction Platform to Support the NeuroEXPLORER. 2025, 00: 1-2. DOI: 10.1109/nss/mic/rtsd57106.2025.11287275.Peer-Reviewed Original ResearchOpen-sourcePeak-to-valley ratioMini-Derenzo phantomReconstruction platformResolution PET scannerImage reconstruction toolsPacket decodingDetector geometryGPU accelerationMemory usagePET scannerPET systemAccurate system modelMotion correctionScatter estimationVendor softwareReconstruction timeImage reconstructionPluginImage qualitySoftwareHuman datasetsSystem modelManufacturing softwareNon-human primatesLR-PET: A Subspace-Based Dynamic PET Imaging via Explicit Non-Negative Low-Rank Factorization
Djebra Y, Najmaoui Y, Chemli Y, Normandin M, Fakhri G, Ma C, Marin T. LR-PET: A Subspace-Based Dynamic PET Imaging via Explicit Non-Negative Low-Rank Factorization. 2025, 00: 1-1. DOI: 10.1109/nss/mic/rtsd57106.2025.11286709.Peer-Reviewed Original ResearchOn Hallucinations in Artificial Intelligence–Generated Content for Nuclear Medicine Imaging (the DREAM Report)
Xia M, Bayerlein R, Chemli Y, Liu X, Ouyang J, Lin M, Fakhri G, Badawi R, Li Q, Liu C. On Hallucinations in Artificial Intelligence–Generated Content for Nuclear Medicine Imaging (the DREAM Report). Journal Of Nuclear Medicine 2025, 67: 166-174. PMID: 41198241, PMCID: PMC12866389, DOI: 10.2967/jnumed.125.270653.Peer-Reviewed Original ResearchYRT-PET: An Open-Source GPU-Accelerated Image Reconstruction Engine for Positron Emission Tomography
Najmaoui Y, Chemli Y, Toussaint M, Petibon Y, Marty B, Fontaine K, Gallezot J, Razdevsek G, Orehar M, Dhaynaut M, Guehl N, Dolenec R, Pestotnik R, Johnson K, Ouyang J, Normandin M, Tetrault M, Lecomte R, Fakhri G, Marin T. YRT-PET: An Open-Source GPU-Accelerated Image Reconstruction Engine for Positron Emission Tomography. IEEE Transactions On Radiation And Plasma Medical Sciences 2025, 10: 535-546. PMID: 41424471, PMCID: PMC12714321, DOI: 10.1109/trpms.2025.3619872.Peer-Reviewed Original ResearchThis study introduces YRT-PET, an open-source GPU-accelerated software for PET image reconstruction, demonstrating high flexibility, speed, and compatibility with existing tools for dynamic imaging and motion correction.In vivo 3D myocardial membrane potential mapping in humans using PET/MRI
Bijari F, Han P, Marin T, Lee W, Chemli Y, Gertsenshteyn I, Mounime I, Djebra Y, Chi D, Normandin M, Ma C, Fakhri G. In vivo 3D myocardial membrane potential mapping in humans using PET/MRI. EJNMMI Research 2025, 15: 93. PMID: 40715686, PMCID: PMC12297085, DOI: 10.1186/s13550-025-01287-7.Peer-Reviewed Original ResearchMembrane potentialExtracellular volume fraction measurementsExtracellular volume fraction mappingBolus-plus-infusion protocolT1 mapping sequencesVolume of distributionWritten Informed ConsentCardiac PET/MR imagingRigid image registrationHumans in vivoContrast agent injectionPET motion correctionFree breathingTracer volume of distributionImage registrationBolus injectionCardiac MRMitochondrial membrane potentialCardiac diseaseHealthy subjectsPET/MR imagingImaging studiesTreatment monitoringAgent injectionPET tracersQuantitative Measurement of Tau Burden in a Dual-Time-Window Dynamic PET Imaging Protocol with [18F]MK6240
Xia Y, Dhaynaut M, Chemli Y, Lois C, Hanseeuw B, Thibault E, Groot C, Ossenkoppele R, Johnson K, El Fakhri G, Normandin M, Guehl N. Quantitative Measurement of Tau Burden in a Dual-Time-Window Dynamic PET Imaging Protocol with [18F]MK6240. Journal Of Nuclear Medicine 2025, 66: 1299-1306. PMID: 40533354, PMCID: PMC12320581, DOI: 10.2967/jnumed.125.270165.Peer-Reviewed Original ResearchDual Prompting for Diverse Count-Level Pet Denoising
Liu X, Huang Y, Marin T, Vafay Eslahi S, Tiss A, Chemli Y, Johnson K, El Fakhri G, Ouyang J. Dual Prompting for Diverse Count-Level Pet Denoising. 2011 IEEE International Symposium On Biomedical Imaging: From Nano To Macro 2025, 00: 1-5. PMID: 40831530, PMCID: PMC12360122, DOI: 10.1109/isbi60581.2025.10980695.Peer-Reviewed Original ResearchFlexible and modular PET: Evaluating the potential of TOF‐DOI panel detectors
Razdevšek G, Fakhri G, Marin T, Dolenec R, Orehar M, Chemli Y, Gola A, Gascon D, Majewski S, Pestotnik R. Flexible and modular PET: Evaluating the potential of TOF‐DOI panel detectors. Medical Physics 2025, 52: 2845-2860. PMID: 40089973, PMCID: PMC12059530, DOI: 10.1002/mp.17741.Peer-Reviewed Original ResearchDepth of interactionLong axial field-of-viewTime-of-flightPanel detectorHigh-performance computing clusterDepth-of-interaction resolutionNoise equivalent count rateDepth-of-interaction capabilityDepth-of-interaction detectorsAxial field-of-viewImage qualityTime-of-flight (TOFDistortion-free imagesPositron emission tomography scannerLong axial fieldComputer clusterSpatial resolutionLSO crystalsImage reconstructionDetector materialCount rateGATE softwareContrast-to-noise ratioParallax errorMonte Carlo simulations