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Xiaolei Su, PhD

Assistant Professor of Cell Biology

Contact Information

Xiaolei Su, PhD

Mailing Address

  • Yale School of Medicine

    333 Cedar St, PO BOX 208002, SHMC 425A

    New Haven, CT, 06520

    United States



Dr. Xiaolei Su obtained his B.S. at Peking University. As a graduate student at Harvard, he revealed a mechanism of microtubule length regulation by kinesin-8 motors under the mentorship of David Pellman. Then he joined Ron Vale's Lab at UCSF as a postdoc fellow. His work led to the discovery that phase separation of membrane-associated proteins can promote T cell activation. As an assistant professor at Yale, Dr. Su is leading a team to explore membrane remodeling and membrane-proximal signal transduction during immune responses. They developed systems for visualizing chimeric antigen receptor (CAR) activation and defined a molecular pathway underlying CAR T activation. Dr. Su's group is also designing CARs with new signaling functions targeting blood, skin, and lung cancers.

Education & Training

  • PhD
    Harvard University, Cell and Developmental Biology (2012)
  • BS
    Peking University, Biological Sciences (2006)
  • Postdoc
    University of California, San Francisco
  • Student
    Physiology Course, Marine Biological Laboratory

Honors & Recognition

Gilead Sciences Research Scholars in Hematology/Oncology2019
Charles H. Hood Foundation Child Health Research Awards2019
Keystone Symposia Future of Science Fund Scholarship2015
Cancer Research Institute Irvington Postdoctoral Fellowship2014
Richard J. Herrnstein Prize for dissertation, Harvard University2012
Lola Ellis Robertson Endowed Scholarship, Marine Biological Laboratory2009

Departments & Organizations