Kazuki Sato, PhD

Featured Publications

• DNAM-1 promotes inflammation-driven tumor development via enhancing IFN-γ production.

  Nakamura-Shinya Y, Iguchi-Manaka A, Murata R, Sato K, Vo AV, Kanemaru K, Shibuya A, Shibuya K. DNAM-1 promotes inflammation-driven tumor development via enhancing IFN-γ production. Int Immunol 2022, 34: 149-157. PMID: 34672321, DOI: 10.1093/intimm/dxab099.

  Peer-Reviewed Original Research

• DNAM-1 regulates Foxp3 expression in regulatory T cells by interfering with TIGIT under inflammatory conditions.

  Sato K, Yamashita-Kanemaru Y, Abe F, Murata R, Nakamura-Shinya Y, Kanemaru K, Muratani M, Veillette A, Goto M, Ito M, Shibuya A, Shibuya K. DNAM-1 regulates Foxp3 expression in regulatory T cells by interfering with TIGIT under inflammatory conditions. Proc Natl Acad Sci U S A 2021, 118 PMID: 34011606, DOI: 10.1073/pnas.2021309118.

  Peer-Reviewed Original Research

• Intestinal Permeability and IgA Provoke Immune Vasculitis Linked to Cardiovascular Inflammation.

  Noval Rivas M, Wakita D, Franklin MK, Carvalho TT, Abolhesn A, Gomez AC, Fishbein MC, Chen S, Lehman TJ, Sato K, Shibuya A, Fasano A, Kiyono H, Abe M, Tatsumoto N, Yamashita M, Crother TR, Shimada K, Arditi M. Intestinal Permeability and IgA Provoke Immune Vasculitis Linked to Cardiovascular Inflammation. Immunity 2019, 51: 508-521.e6. PMID: 31471109, DOI: 10.1016/j.immuni.2019.05.021.

  Peer-Reviewed Original Research

• Identification and isolation of splenic tissue-resident macrophage sub-populations by flow cytometry.

  Fujiyama S, Nakahashi-Oda C, Abe F, Wang Y, Sato K, Shibuya A. Identification and isolation of splenic tissue-resident macrophage sub-populations by flow cytometry. Int Immunol 2019, 31: 51-56. PMID: 30256964, DOI: 10.1093/intimm/dxy064.

  Peer-Reviewed Original Research

• Cutting Edge: Identification of Marginal Reticular Cells as Phagocytes of Apoptotic B Cells in Germinal Centers.

  Sato K, Honda SI, Shibuya A, Shibuya K. Cutting Edge: Identification of Marginal Reticular Cells as Phagocytes of Apoptotic B Cells in Germinal Centers. J Immunol 2018, 200: 3691-3696. PMID: 29686051, DOI: 10.4049/jimmunol.1701293.

  Peer-Reviewed Original Research

• Improved protocol for the isolation of naïve follicular dendritic cells.

  Sato K, Honda SI, Shibuya A, Shibuya K. Improved protocol for the isolation of naïve follicular dendritic cells. Mol Immunol 2016, 78: 140-145. PMID: 27639061, DOI: 10.1016/j.molimm.2016.09.011.

  Peer-Reviewed Original Research

• Marginal zone B cells exacerbate endotoxic shock via interleukin-6 secretion induced by Fcα/μR-coupled TLR4 signalling.

  Honda S, Sato K, Totsuka N, Fujiyama S, Fujimoto M, Miyake K, Nakahashi-Oda C, Tahara-Hanaoka S, Shibuya K, Shibuya A. Marginal zone B cells exacerbate endotoxic shock via interleukin-6 secretion induced by Fcα/μR-coupled TLR4 signalling. Nat Commun 2016, 7: 11498. PMID: 27146354, DOI: 10.1038/ncomms11498.

  Peer-Reviewed Original Research

• Increased CD11b(+) Gr-1(+) cell population in the placenta after infection with Toxoplasma gondii.

  Takeshima K, Sato K, Nabekura T, Nagamune K, Hamada H, Yoshikawa H, Shibuya A, Shibuya K. Increased CD11b(+) Gr-1(+) cell population in the placenta after infection with Toxoplasma gondii. Microbiol Immunol 2015, 59: 95-8. PMID: 25557654, DOI: 10.1111/1348-0421.12225.

  Peer-Reviewed Original Research

• Molecular characterization of the dimer formation of Fcα/μ receptor (CD351).

  Takagaki K, Satoh K, Honda S, Shibuya A. Molecular characterization of the dimer formation of Fcα/μ receptor (CD351). Mol Immunol 2013, 56: 23-7. PMID: 23665380, DOI: 10.1016/j.molimm.2013.04.003.

  Peer-Reviewed Original Research