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Xiaolei Su, PhD

Assistant Professor of Cell Biology

Contact Information

Xiaolei Su, PhD

Mailing Address

  • Yale School of Medicine

    333 Cedar St, PO BOX 208002, SHMC 425A

    New Haven, CT 06520

    United States



Dr. Xiaolei Su obtained his B.S. at Peking University. As a graduate student at Harvard, he revealed a mechanism of microtubule length regulation by kinesin-8 motors under the mentorship of David Pellman. Then he joined Ron Vale's Lab at UCSF as a postdoc fellow. His work led to the discovery that phase separation of membrane-associated proteins can promote T cell activation. As an assistant professor at Yale, Dr. Su is leading a team to explore membrane remodeling and signal transduction during immune responses. They combined in vitro reconstitution with live cell imaging to understand how biomolecular condensates regulate immune signaling. They also investigated the molecular pathways underlying CAR T activation and designed CARs with new signaling functions targeting blood, skin, and lung cancers.

Education & Training

  • Postdoc
    University of California, San Francisco (2017)
  • PhD
    Harvard University, Cell and Developmental Biology (2012)
  • Student
    Physiology Course, Marine Biological Laboratory (2009)
  • BS
    Peking University, Biological Sciences (2006)

Honors & Recognition

AwardAwarding OrganizationDate
Gabrielle's Angel Foundation Medical Research AwardGabrielle's Angel Foundation2023
American Cancer Society Research Scholar GrantAmerican Cancer Society2022
Human Frontier Science Program Early-Career Research GrantHuman Frontier Science Program2021
Rally Young ScholarRally Foundation2021
Gilead Sciences Research Scholars in Hematology/OncologyGilead Sciences2019
Charles H. Hood Foundation Child Health Research AwardsCharles H. Hood Foundation2019
Keystone Symposia Future of Science Fund ScholarshipKeystone2015
Cancer Research Institute Irvington Postdoctoral FellowshipCancer Research Inistitute2014
Richard J. Herrnstein Prize for dissertation, Harvard UniversityHarvard University2012
Lola Ellis Robertson Endowed Scholarship, Marine Biological LaboratoryMarine Biological Laboratory2009

Departments & Organizations