Xiaolei Su, PhD
Biography
Research & Publications
News
Appointments
Biography
Dr. Xiaolei Su obtained his B.S. at Peking University. As a graduate student at Harvard, he revealed a mechanism of microtubule length regulation by kinesin-8 motors under the mentorship of David Pellman. Then he joined Ron Vale's Lab at UCSF as a postdoc fellow. His work led to the discovery that phase separation of membrane-associated proteins can promote T cell activation. As an assistant professor at Yale, Dr. Su is leading a team to explore membrane remodeling and signal transduction during immune responses. They combined in vitro reconstitution with live cell imaging to understand how biomolecular condensates regulate immune signaling. They also investigated the molecular pathways underlying CAR T activation and designed CARs with new signaling functions targeting blood, skin, and lung cancers.
Education & Training
- PostdocUniversity of California, San Francisco (2017)
- PhDHarvard University, Cell and Developmental Biology (2012)
- StudentPhysiology Course, Marine Biological Laboratory (2009)
- BSPeking University, Biological Sciences (2006)
Honors & Recognition
Award | Awarding Organization | Date |
---|---|---|
Gabrielle's Angel Foundation Medical Research Award | Gabrielle's Angel Foundation | 2023 |
American Cancer Society Research Scholar Grant | American Cancer Society | 2022 |
Human Frontier Science Program Early-Career Research Grant | Human Frontier Science Program | 2021 |
Rally Young Scholar | Rally Foundation | 2021 |
Gilead Sciences Research Scholars in Hematology/Oncology | Gilead Sciences | 2019 |
Charles H. Hood Foundation Child Health Research Awards | Charles H. Hood Foundation | 2019 |
Keystone Symposia Future of Science Fund Scholarship | Keystone | 2015 |
Cancer Research Institute Irvington Postdoctoral Fellowship | Cancer Research Inistitute | 2014 |
Richard J. Herrnstein Prize for dissertation, Harvard University | Harvard University | 2012 |
Lola Ellis Robertson Endowed Scholarship, Marine Biological Laboratory | Marine Biological Laboratory | 2009 |
Departments & Organizations
- Biochemistry, Quantitative Biology, Biophysics and Structural Biology (BQBS)
- Cancer Immunology
- Cell Biology
- Molecular Cell Biology, Genetics and Development
- Yale Cancer Center
- Yale Center for Immuno-Oncology
- Yale Combined Program in the Biological and Biomedical Sciences (BBS)