Vinod H. Srihari, MD
Professor of PsychiatryDownloadHi-Res Photo
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Additional Titles
Director, STEP Program
Fellow, Davenport College
Contact Info
Psychiatry
34 Park Street
New Haven, CT 06519
United States
About
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Titles
Professor of Psychiatry
Director, STEP Program; Fellow, Davenport College
Biography
Dr. Srihari's scholarly focus is on improving the outcomes of early course schizophrenia spectrum disorders. His research interests span the translational continuum from studies of etiology and pathophysiology to interventions on clinical samples, to service level innovations. As Director of the STEP Program, he leads activities that connect this research to the missions of delivering a model service (the STEP Clinic), disseminating clinical best practices (via Learning Health Networks), education and workforce development and influencing policies that support the public health mission of early Intervention for schizophrenia spectrum disorders.
In his curricular work, he has led the development and implementation of an Evidence-Based Medicine (EBM) based approach to enabling psychiatrists in training to ask, access, appraise and apply the best available scientific evidence to their practice and to audit the health of the populations they are responsible for.
Dr. Srihari also consults with academic and non-academic healthcare systems that seek to initiate or refine early intervention services for recent onset or 'first-episode' psychosis.
Last Updated on May 07, 2025.
Appointments
Psychiatry
ProfessorPrimary
Other Departments & Organizations
- Center for Brain & Mind Health
- Connecticut Mental Health Center
- Division of Neurocognition, Neurocomputation & Neurogenetics
- Division of Public Psychiatry Research
- Global Health Studies
- Psychiatry
- Psychosis Program at Yale
- South Asian Studies
- Specialized Treatment for Early Psychosis (STEP) Program
- Yale Biomedical Imaging Institute
- Yale Global Mental Health Program
- Yale New Haven Health System
- Yale Ventures
Education & Training
- Fellow
- Yale University School of Medicine (2005)
- Resident
- Yale University School of Medicine (2003)
- MD
- University of Rochester (1998)
- BA
- University of Rochester, Biology; Religion & Classics (1994)
Board Certifications
Psychiatry
- Certification Organization
- AB of Psychiatry & Neurology
- Latest Certification Date
- 2025
- Original Certification Date
- 2005
Research
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Overview
Medical Research Interests
Biomarkers; Curriculum; Evidence-Based Medicine; Exosomes; Health Care Quality, Access, and Evaluation; Learning Health System; Mental Health Services; Mitochondrial Diseases; Oxidative Stress; Population Health; Psychotic Disorders; Public Health Informatics; Schizophrenia Spectrum and Other Psychotic Disorders
Public Health Interests
Capacity Building; Health Policy
ORCID
0000-0003-1556-2332- View Lab Website
STEP
Research at a Glance
Yale Co-Authors
Frequent collaborators of Vinod H. Srihari's published research.
Publications Timeline
A big-picture view of Vinod H. Srihari's research output by year.
Research Interests
Research topics Vinod H. Srihari is interested in exploring.
Fangyong Li, MS, MPH
Maria Ferrara, MD
Cenk Tek, MD
Hadar Hazan, PhD
Laura Yoviene Sykes, PhD
Sinan Guloksuz, MD, PhD
135Publications
5,331Citations
Psychotic Disorders
Mental Health Services
Evidence-Based Medicine
Learning Health System
Exosomes
Biomarkers
Publications
2026
Changes in cannabis use following legalization: Effects in first-episode psychosis
Purushothaman D, Tayfur S, Song Z, Li F, Corbera S, Sykes L, Riley S, Terashima J, D'Souza D, Tek C, Srihari V. Changes in cannabis use following legalization: Effects in first-episode psychosis. Schizophrenia Research 2026, 290: 86-87. PMID: 41671766, DOI: 10.1016/j.schres.2026.02.001.Commentaries, Editorials and LettersThis study investigates how cannabis legalization in Connecticut increased moderate-to-severe cannabis use among first-episode psychosis patients, raising concerns about potential health risks.Do early intervention services for psychosis maintain their effects after transition to usual/modular care? A systematic review and meta‐analysis
Salazar de Pablo G, Almeida J, Camacho J, Suárez Campayo J, Catalan A, Pop M, Aymerich C, Rogdaki M, Robinson D, Schooler N, McGuire P, Chang W, Chen E, Nordentoft M, Hjorthøj C, Albert N, Starzer M, Srihari V, Valencia M, Arango C, Kane J, Fusar-Poli P, Correll C. Do early intervention services for psychosis maintain their effects after transition to usual/modular care? A systematic review and meta‐analysis. World Psychiatry 2026, 25: 95-104. PMID: 41536085, PMCID: PMC12805053, DOI: 10.1002/wps.70012.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsAltmetricConceptsEarly intervention servicesNegative symptomsAntipsychotic useSuicide attemptsEIS careRandomized Controlled TrialsIntervention servicesMaintenance effectsEarly-phase psychosisDuration of hospitalizationQuality of lifeDrop-outCochrane Central RegisterCochrane Central Register of ReviewsPsychiatric hospitalMeta-analyzed outcomesPsychosisCo-primary outcomesIntervention groupSuicideIntervention periodWeb of Science databasesFollow-upCareSystematic review
2025
Instruments for assessing insight in psychosis: A systematic review of psychometric properties
Hazan H, Tayfur S, Karmani S, Gibbs-Dean T, Mourgues C, Srihari V. Instruments for assessing insight in psychosis: A systematic review of psychometric properties. Psychological Medicine 2025, 55: e362. PMID: 41292267, PMCID: PMC12671917, DOI: 10.1017/s0033291725101918.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsThis study investigates tools for assessing insight in psychosis, finding most scales reliable but highlighting the need for culturally adaptive, multidimensional measures for better clinical and research utility.Learning health systems for first-episode psychosis: Insights from North America
Srihari V, Keshavan M. Learning health systems for first-episode psychosis: Insights from North America. Schizophrenia Research 2025, 286: a1-a5. PMID: 41224594, DOI: 10.1016/j.schres.2025.10.025.Commentaries, Editorials and LettersThis special issue explores how learning health systems enhance early psychosis care by integrating research, quality improvement, and stakeholder collaboration to improve patient outcomes and generate new insights.The potential of AI for scale development: A self-report psychosis symptoms measure using ChatGPT
Tayfur S, Hazan H, Li F, Song Z, Corbera S, Tek C, Srihari V. The potential of AI for scale development: A self-report psychosis symptoms measure using ChatGPT. Schizophrenia Research 2025, 284: 111-113. PMID: 40763549, DOI: 10.1016/j.schres.2025.07.030.Commentaries, Editorials and LettersCitationsUtilization of a psychosis consultation service: Early lessons from a statewide initiative
Tayfur S, Yoviene Sykes L, Tek C, Srihari V. Utilization of a psychosis consultation service: Early lessons from a statewide initiative. Schizophrenia Research 2025, 282: 198-202. PMID: 40614351, PMCID: PMC12276959, DOI: 10.1016/j.schres.2025.06.019.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsRecent-onset psychosisEarly psychosis interventionContinuing carePsychosis programPsychosis interventionPsychosisCare of young peoplePsychosis careTransitions of careConsultation serviceLearning health systemFamily support strategiesClinical issuesSpecialty careLearning CollaborativeHealthcare leadersHealth systemOut-of-stateStatewide initiativeFamily engagementTeam meetingsSupport strategiesSpecial treatmentCareEarly lessonsPsychiatric Hospitalization After Enrollment in Coordinated Specialty Care: Unexpected Gender- and Age-Related Disparities
Vohs J, Tayfur S, Li F, Song Z, Breitborde N, Cahill J, Chaudhry S, Ferrara M, Heckers S, Satchivi A, Silverstein S, Taylor S, Tso I, Weiss A, Breier A, Srihari V. Psychiatric Hospitalization After Enrollment in Coordinated Specialty Care: Unexpected Gender- and Age-Related Disparities. Schizophrenia Bulletin 2025, 52: sbaf260. PMID: 41863376, PMCID: PMC13005094, DOI: 10.1093/schbul/sbaf260.Peer-Reviewed Original ResearchMeSH Keywords and ConceptsConceptsLength of stayLonger length of stayFirst-episode psychosisEarly Psychosis Intervention NetworkCoordinated Specialty CareEarly psychosis careAge-related disparitiesBlack/African American participantsNegative binomial regressionPsychosis careIntervention NetworkSpecialty careMultidisciplinary interventionWhite participantsHospitalization ratesPsychiatric hospitalBinomial regressionHospital outcomesElevated riskFunctional declineFrequent admissionsPrimary outcomeHospitalization frequencyHealthcare burdenFrequent hospitalizationsEnhancing Coordinated Specialty Care Through Early Detection: Impact of Reduced Duration of Untreated Psychosis
Hazan H, Ferrara M, Zhou B, Li F, Imetovski S, Sykes L, Pollard J, Cahill J, Gibbs-Dean T, Corbera S, Karmani S, Riley S, Tayfur S, Tek C, Keshavan M, Srihari V. Enhancing Coordinated Specialty Care Through Early Detection: Impact of Reduced Duration of Untreated Psychosis. Schizophrenia Bulletin 2025, 51: 1730-1737. PMID: 40339151, PMCID: PMC12597490, DOI: 10.1093/schbul/sbaf044.Peer-Reviewed Original ResearchCitationsConceptsDuration of untreated psychosisFirst-episode psychosisCoordinated Specialty CareUntreated psychosisMediation analysisShorter duration of untreated psychosisFirst-episode psychosis patientsEarly interventionEarly psychosisBenefits of early interventionPsychosisGAFFunctional outcomesGlobal assessmentEarly detection campaignsSpecialty careIntake processRecovery outcomesSpecial treatmentQuality of lifeStreamlining referralsFunctional recoveryScoresPatientsInterventionInsight and Its Trajectory: Predicting the Risk of Psychiatric Hospitalizations Among First-Episode Psychosis During the First Year of Coordinated Specialty Care
Hazan H, Ferrara M, Gibbs-Dean T, Tayfur S, Corbera S, Karmani S, Song Z, Li F, Vlachos I, Selakovic M, Tek C, Srihari V. Insight and Its Trajectory: Predicting the Risk of Psychiatric Hospitalizations Among First-Episode Psychosis During the First Year of Coordinated Specialty Care. Schizophrenia Bulletin 2025, 52: sbaf019. PMID: 40227145, PMCID: PMC12809808, DOI: 10.1093/schbul/sbaf019.Peer-Reviewed Original ResearchCitationsConceptsCoordinated Specialty CareFirst-episode psychosisBaseline insightRisk of psychiatric hospitalizationFirst-episodeEarly psychosisInsight groupLength of stayPsychiatric hospitalSpecialty carePsychosisLongitudinal trajectoriesGreater reductionsHospital outcomesHigh-low-highPredicting clinical improvementHospital dataModifiable factorsMonths pre-ParticipantsHospitalization riskClinical improvementRecovery trajectoriesReduce hospitalizationsBaselineHONE: A learning health system platform for advancing early intervention in first episode psychosis
Mathis W, Gibbs-Dean T, Cahill J, Srihari V. HONE: A learning health system platform for advancing early intervention in first episode psychosis. Schizophrenia Research 2025, 280: 1-9. PMID: 40209525, PMCID: PMC12052476, DOI: 10.1016/j.schres.2025.04.009.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsLearning health systemEarly intervention servicesFirst-episode psychosisLearning health system frameworkQuality improvementDiverse healthcare settingsContinuous quality improvementMental health outcomesUser-centered designPatient-reported outcomesEvidence-based outcomesDiverse data sourcesCare deliveryEpisode psychosisImprove careKnowledge translationHealth outcomesHealth systemHealthcare settingsLifetime illnessHealthcare reformData visualizationUser engagementTransformation frameworkDuration of untreated psychosis
Clinical Trials
Current Trials
MitoQ for improving cognition in early course psychosis illnesses
IRB ID2000038056RolePrincipal InvestigatorPrimary Completion Date12/31/2027Recruiting ParticipantsStudy of Brain Function Across the Lifespan
IRB ID2000020891RoleSub InvestigatorPrimary Completion Date07/31/2022Recruiting ParticipantsGenderBothAge18 years - 65 years
Academic Achievements & Community Involvement
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Activities
activity Schizophrenia Research
07/01/2018 - PresentJournal ServiceEditorial Board Memberactivity Schizophrenia International Research Society (SIRS)
07/01/2015 - PresentProfessional OrganizationsMemberactivity International Early Psychosis Association (IEPA)
07/01/2005 - PresentProfessional OrganizationsMemberactivity Center for Evidence Based Medicine (CEBM), Oxford, U.K.
07/01/2005 - PresentProfessional OrganizationsMemberactivity Early Psychosis Collaboration
02/01/2021 - PresentResearchDetailsFerrara, Emilia-Romagna, ItalyCollaboratorsAbstract/SynopsisBuilding a European hub for collaborative clinical and research projects.
Honors
honor Stephen Fleck Award
06/08/2018Yale School of Medicine AwardYale University Department of PsychiatryDetailsUnited Stateshonor PRA Teaching Award
06/10/2011Yale School of Medicine AwardYale Psychiatry Residents AssociationDetailsUnited Stateshonor Model Curriculum in Evidence-Based Mental Health
03/04/2011National AwardAmerican Association of Directors of Psychiatric Residency TrainingDetailsUnited Stateshonor Chairman's Award
06/15/2007Yale School of Medicine AwardYale University Department of PsychiatryDetailsUnited Stateshonor Resident Teaching Award
06/15/2004Yale School of Medicine AwardYale University Department of PsychiatryDetailsUnited States
News & Links
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Media
MindmapCT Featured on Connecticut’s Morning Buzz
The Mindmap campaign is expanding statewide across Connecticut. Connecticut’s Morning Buzz Host Natasha Lubczenko was joined in the studio by Dr. Laura Yoviene Sykes, PhD and Dr. Vinod Srihari, MD, from the Yale School of Medicine’s STEP Learning Collaborative Program to discuss this important campaign, designed to educate and empower the public on first episode psychosis.
News
- May 20, 2026
Hyman Honored with 2026 Yale Department of Psychiatry Mental Health Advocacy Award
- April 08, 2026
Yale-NAMI Conference on Neuroscience, Mental Health and Society Scheduled for May 9
- February 15, 2026
After Legalization: More Severe and Concerning Cannabis Use in First-Episode Psychosis
- December 16, 2025
Srihari Guest Edits Special Issue of 'Schizophrenia Research'
Get In Touch
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Contacts
Mailing Address
Psychiatry
34 Park Street
New Haven, CT 06519
United States
Locations
The STEP Program
Lab
Connecticut Mental Health Center
34 Park Street
New Haven, CT 06519