Uma Reddy, MD, MPH
Professor Adjunct of Obstetrics, Gynecology & Reproductive SciencesAbout
Titles
Professor Adjunct of Obstetrics, Gynecology & Reproductive Sciences
Biography
Dr. Reddy graduated from Brown University Magna cum laude and received her M.D. degree from the Warren Alpert Medical School of Brown University. Dr. Reddy also earned a Masters in Public Health (M.P.H.) from the Johns Hopkins Bloomberg School of Public Health. She completed her residency in Obstetrics and Gynecology at the Johns Hopkins Hospital and remained there as a Robert Wood Johnson Clinical Scholar. She completed her Maternal-Fetal Medicine fellowship at Thomas Jefferson University. She was a faculty member at the University of Maryland School of Medicine prior to joining the National Institutes of Health (NIH) as a Medical Officer in the Pregnancy and Perinatology Branch of the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD). During her tenure at NIH, she provided MFM clinical services at Walter Reed Medical Center (Bethesda, MD) and then Medstar Washington Hospital Center (Washington, DC) as a Professor of Obstetrics and Gynecology at the Georgetown University School of Medicine prior to joining Yale in 2018.
While at NIH, she oversaw many of the largest and most influential studies in obstetrics, including directing the Maternal-Fetal Medicine Units (MFMU) Network which funds multiple clinical trials across the country. Her research on stillbirth as part of the Stillbirth Collaborative Research Network (SCRN), preterm birth and labor management has had a profound impact on obstetrical practice both in the United States and internationally. She received numerous NIH awards for her role in advancing women’s health research agenda nationally.
Dr. Reddy is widely recognized as a scholar, educator, and mentor. Dr. Reddy has been selected to serve as a Member of the American College of Obstetrics and Gynecology (ACOG) Committee on Practice Bulletins – Obstetrics; Fellow of the American Gynecological & Obstetrical Society and was selected as Fellow in Executive Leadership in Academic Medicine (ELAM) Program for Women, 2020-2021 Class. She has published 250 peer reviewed articles, many in the most impactful journals including NEJM and JAMA.
Dr. Reddy is board certified in Obstetrics and Gynecology and Maternal-Fetal Medicine. Her expertise is in the management of high-risk pregnancies complicated by prior preterm birth or pregnancy loss as well as maternal conditions such as diabetes, hypertension, and connective tissue disorders such as lupus.
Appointments
Departments & Organizations
- Improving Clinical Care for Recurrent Pregnancy Loss
- Yale Center for Genomic Health
Education & Training
- Fellow
- Thomas Jefferson University (2000)
- MPH
- Johns Hopkins Bloomberg School of Public Health, Biostatistics (1999)
- Robert Wood Johnson Clinical Scholar
- Johns Hopkins University (1997)
- Resident
- Johns Hopkins Hospital (1995)
- Intern
- Johns Hopkins Hospital (1992)
- MD
- The Warren Alpert Medical School of Brown University (1991)
- ScB
- Brown University, Biology (1988)
Research
Overview
Medical Subject Headings (MeSH)
Research at a Glance
Yale Co-Authors
Publications Timeline
Research Interests
Heping Zhang, PhD
Audrey Merriam, MD, MS
Jennifer Culhane
Katherine Harper Campbell, MD, MPH
Lena Sweeney
Lisbet Lundsberg, PhD
Pregnant Women
Publications
2024
Oxytocin regimen used for induction of labor and pregnancy outcomes
REDDY U, SANDOVAL G, TITA A, SILVER R, MALLETT G, Kim H, EL-SAYED Y, RICE M, WAPNER R, ROUSE D, SAADE G, THORP J, CHAUHAN S, COSTANTINE M, CHIEN E, CASEY B, SRINIVAS S, SWAMY G, SIMHAN H, MACONES G, GROBMAN W, Network E. Oxytocin regimen used for induction of labor and pregnancy outcomes. American Journal Of Obstetrics & Gynecology MFM 2024, 101508. PMID: 39357802, DOI: 10.1016/j.ajogmf.2024.101508.Peer-Reviewed Original ResearchConceptsInduction of laborLow-risk nulliparous patientsOxytocin regimensAdjusted relative risksAdjusted odds ratiosCesarean deliveryComposite of perinatal deathConfidence intervalsNeonatal respiratory supportLow-dose regimensHigh-dose oxytocin regimenSevere neonatal complicationsOperative vaginal delivery rateFrequency of cesarean deliverySecondary analysisEstimate adjusted relative risksElective induction of laborPerinatal deathRoutine induction of labourEstimate adjusted odds ratiosVaginal delivery rateRespiratory supportNulliparous patientsMHD groupMultivariable Poisson regressionPatient and Community Centered Approaches to Sepsis Among Birthing People
Richardson B, Cepin A, Grilo S, Moss R, Moller M, Brown S, Goffman D, Friedman A, Reddy U, Hall K. Patient and Community Centered Approaches to Sepsis Among Birthing People. Seminars In Perinatology 2024, 151974. PMID: 39341761, DOI: 10.1016/j.semperi.2024.151974.Peer-Reviewed Original ResearchAltmetricConceptsMaternal health equityHealth equityAcademic-community research partnershipsSevere maternal morbidityCo-designed interventionsBirthing peopleMaternal deathsUnderserved communitiesMaternal morbidityMoms studyResearch partnershipsSepsis-related morbidityCommunity centered approachRisk periodResearch principalsResearch processCentered approachCommunityMorbidityPeoplePostpartumInterventionEquityPartnershipBirthThe association between perinatal depressive symptoms and child neurodevelopment
Miller E, Costantine M, Mele L, Varner M, Reddy U, Wapner R, Thorp J, Saade G, Tita A, Rouse D, Sibai B, Mercer B, Caritis S, Casey B, Eunice Kennedy Shriver National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network B. The association between perinatal depressive symptoms and child neurodevelopment. American Journal Of Obstetrics & Gynecology MFM 2024, 6: 101488. PMID: 39293588, DOI: 10.1016/j.ajogmf.2024.101488.Peer-Reviewed Original ResearchAltmetricConceptsSocial determinants of healthPerinatal depressive symptomsDeterminants of healthDepression screeningYears of ageDepressive symptomsSocial determinantsCES-DPositive postpartum depression screenAntenatal depression screeningPerinatal depression screeningPostpartum depression screeningCES-D <Child neurodevelopmentOne-year postpartumAdverse neurodevelopmental outcomesMulticenter randomized trialMultivariate logistic regressionBirthing peoplePerinatal depressionYear postpartumChild cognitive outcomesIQ score <Thyroxine therapyNeurodevelopmental outcomesBlood Pressure Control in Pregnant Patients with Chronic Hypertension and Diabetes: Should <130/80 be the Target?
Harper L, Kuo H, Boggess K, Dugoff L, Sibai B, Lawrence K, Hughes B, Bell J, Aagaard K, Edwards R, Gibson K, Haas D, Plante L, Metz T, Casey B, Esplin S, Longo S, Hoffman M, Saade G, Hoppe K, Foroutan J, Tuuli M, Owens M, Simhan H, Frey H, Rosen T, Palatnik A, August P, Reddy U, Kinzler W, Su E, Krishna I, Nguyen N, Norton M, Skupski D, El-Sayed Y, Galis Z, Ambalavanan N, Oparil S, Szychowski J, Tita A. Blood Pressure Control in Pregnant Patients with Chronic Hypertension and Diabetes: Should <130/80 be the Target? American Journal Of Obstetrics And Gynecology 2024 PMID: 39288828, DOI: 10.1016/j.ajog.2024.09.006.Peer-Reviewed Original ResearchAltmetricConceptsTarget blood pressureNeonatal intensive care unitLow blood pressure groupBlood pressure groupPerinatal outcomesAverage blood pressureChronic hypertensionMm HgBlood pressureCesarean deliveryNeonatal deathDiastolic BPRisk of NICU admissionCompare perinatal outcomesEvaluate risk ratiosLt;130/80 mm HgPreterm birth <Adverse perinatal outcomesMultivariable log-binomial regression modelsGoal blood pressureAverage diastolic BPPrimary composite outcomeSystolic BP <Log-binomial regression modelsAntenatal blood pressureLarge-Scale Proteomics in Early Pregnancy and Hypertensive Disorders of Pregnancy
Greenland P, Segal M, McNeil R, Parker C, Pemberton V, Grobman W, Silver R, Simhan H, Saade G, Ganz P, Mehta P, Catov J, Merz C, Varagic J, Khan S, Parry S, Reddy U, Mercer B, Wapner R, Haas D. Large-Scale Proteomics in Early Pregnancy and Hypertensive Disorders of Pregnancy. JAMA Cardiology 2024, 9: 791-799. PMID: 38958943, PMCID: PMC11223045, DOI: 10.1001/jamacardio.2024.1621.Peer-Reviewed Original ResearchAltmetricConceptsArea under the receiver operating characteristic curveCase-control studyHypertensive disordersEarly pregnancyClinical dataSmall-for-gestational-age infantsPrediction of hypertensive disordersSmall-for-gestational-ageHypertensive disorders of pregnancyPrediction of HDPDisorders of pregnancyNested case-control studyPlasma samplesMulticenter observational studyStored plasma samplesReceiver operating characteristic curveBody mass indexGestational hypertensionNon-Hispanic blacksPreterm birthFetal sexFirst-trimesterNon-Hispanic whitesPregnancy outcomesMaternal raceCannabis Exposure and Adverse Pregnancy Outcomes Related to Placental Function
Metz T, Allshouse A, McMillin G, Greene T, Chung J, Grobman W, Haas D, Mercer B, Parry S, Reddy U, Saade G, Simhan H, Silver R. Cannabis Exposure and Adverse Pregnancy Outcomes Related to Placental Function. Obstetric Anesthesia Digest 2024, 44: 139-140. DOI: 10.1097/01.aoa.0001026572.72882.bd.Peer-Reviewed Original ResearchConceptsExposure to cannabisCannabis usePlacental functionPregnancy outcomesPrevalence of cannabis usePoor fetal growthAdverse pregnancy outcomesInfluence pregnancy outcomePlacental dysfunctionCannabis exposureFetal growthPregnant individualsSelf-reported useTobacco useCannabisDrug usePregnancyOutcome relationsPotential legal consequencesOutcomesAssociationExposureUseDysfunctionPublished researchPregnancy Outcomes in Patients With Hepatitis C Virus Infection
Hughes B, Sandoval G, Saade G, Clifton R, Reddy U, Bartholomew A, Salazar A, Chien E, Tita A, Thorp J, Metz T, Wapner R, Sabharwal V, Simhan H, Swamy G, Heyborne K, Sibai B, Grobman W, El-Sayed Y, Casey B, Parry S, Macones G, Prasad M. Pregnancy Outcomes in Patients With Hepatitis C Virus Infection. Obstetrics And Gynecology 2024, 144: 501-506. PMID: 39173174, DOI: 10.1097/aog.0000000000005703.Peer-Reviewed Original ResearchAltmetricConceptsSmall-for-gestational-ageHepatitis C virusHepatitis C virus infectionCase groupIncreased oddsPreterm birthNeonatal infectionGestational diabetesMaternal outcomesHCV infectionBirth weightSmall-for-gestational-age birth weightAdmission to neonatal intensive careControl groupIncreased odds of preterm birthPositive hepatitis C virusOdds of NICU admissionOutcomes associated with pregnancyMulticenter prospective cohort studyOdds of preterm birthMaternal HCV infectionMaternal medical comorbiditiesSGA birth weightAdverse maternal outcomesC virus infectionRadon exposure and gestational diabetes mellitus: the nuMoM2b study
Zhang Y, Angley M, Lu L, Smith B, Grobman W, Wylie B, Reddy U, Kahe K. Radon exposure and gestational diabetes mellitus: the nuMoM2b study. ISEE Conference Abstracts 2024, 2024 DOI: 10.1289/isee.2024.0948.Peer-Reviewed Original ResearchAntepartum yoga and pregnancy outcomes in nulliparous individuals: a retrospective cohort study
Kawakita T, Atwani R, Huang J, Greenland P, Merz C, Grobman W, Christman M, Silver R, Mcneil R, Reddy U, Chung J, Parry S, Saade G. Antepartum yoga and pregnancy outcomes in nulliparous individuals: a retrospective cohort study. American Journal Of Obstetrics & Gynecology MFM 2024, 6: 101465. PMID: 39142536, DOI: 10.1016/j.ajogmf.2024.101465.Peer-Reviewed Original ResearchMaternal implications of fetal anomalies: a population-based cross-sectional study
Atwani R, Aziz M, Saade G, Reddy U, Kawakita T. Maternal implications of fetal anomalies: a population-based cross-sectional study. American Journal Of Obstetrics & Gynecology MFM 2024, 6: 101440. PMID: 39089580, DOI: 10.1016/j.ajogmf.2024.101440.Peer-Reviewed Original ResearchAltmetricConceptsCongenital diaphragmatic herniaCongenital heart diseasePresence of fetal anomaliesAdjusted relative risksFetal anomaliesCleft lipMaternal morbidityDiaphragmatic herniaAdjusted risk differencesChromosomal disordersMultiple anomaliesLimb anomaliesHeart diseaseMaternal intensive care unit admissionRisk of severe maternal morbidityAssociated with maternal morbidityCyanotic congenital heart diseaseMultiple fetal anomaliesRisk of SMMAdverse maternal health outcomesIntensive care unit admissionAdverse maternal outcomesPopulation-based cross-sectional studySevere maternal morbidityIncreased absolute risk
Academic Achievements & Community Involvement
honor NICHD Individual Merit Award for leading the Opioid Research Effort
National AwardThe Eunice Kennedy Shriver National Institute for Child Health and Human DevelopmentDetails01/01/2017United Stateshonor NICHD Merit Award for NICHD Clinical Trials Stewardship Working Group
National AwardThe Eunice Kennedy Shriver National Institute for Child Health and Human DevelopmentDetails12/01/2015United Stateshonor National Institutes Office of the Director Honor Award for Team to Re-Engineer Scientific Oversight of Women and Minority Inclusion
National AwardNational Institutes OfficeDetails01/01/2015United Stateshonor National Institutes of Health Director’s Group Award for Pregnancy and Perinatology Branch Stillbirth Research Team
National AwardNational InstitutesDetails01/01/2014United Stateshonor National Institutes of Health Merit Award for Leadership of stillbirth research that has contributed to the successful accomplishment of the NICHD mission
National AwardThe Eunice Kennedy Shriver National Institute for Child Health and Human DevelopmentDetails01/01/2012United States
News
News
- July 02, 2021
Repeat Pregnancy Loss Will Be Focus of Genetic Study
- September 17, 2020
A Pregnancy Ended by COVID-19 Informs New Understanding and Protocols
- September 01, 2020Source: Journal of Clinical Investigation
Yale OB COVID Study Makes the Cover of JCI
- May 29, 2020Source: Nature Medicine
Nature Medicine's COVID-19 Research in Brief: 9 May to 15 May, 2020