Maohan Su
Research Scientist in Cell BiologyCards
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Research
Publications
2026
Mitotic Cdc42 waves encode PI(3,4)P2 signaling and Golgi morphological state to control spindle scaling
Fung S, Xiao S, Bao Y, Graham M, Su M, Liu X, Bewersdorf J, Wu M. Mitotic Cdc42 waves encode PI(3,4)P2 signaling and Golgi morphological state to control spindle scaling. Science Advances 2026, 12: eaec7705. PMID: 42319936, PMCID: PMC13281794, DOI: 10.1126/sciadv.aec7705.Peer-Reviewed Original ResearchMast cell extracellular granules are bioactive condensates assembled by heparin and polyamine
Xiong Y, Tomares D, Guo J, Sato K, Zeng L, Tian Y, Su M, Albis A, Pant A, Pappu R, Su X. Mast cell extracellular granules are bioactive condensates assembled by heparin and polyamine. Nature Chemical Biology 2026, 22: 1120-1131. PMID: 41760814, PMCID: PMC13010460, DOI: 10.1038/s41589-026-02165-6.Peer-Reviewed Original ResearchThis study investigates how mast cell extracellular granules form via interactions between heparin and polyamines, creating unique microenvironments that enhance immune mediator activity.
2025
TUG protein acts through a disordered region to organize the early secretory pathway
Parchure A, Tejada H, Xi Z, Kim Y, Su M, Yan Y, Julca-Zevallos O, Alcázar-Román A, Villemeur M, Liu X, Toomre D, Raote I, Bogan J. TUG protein acts through a disordered region to organize the early secretory pathway. Nature Communications 2025, 16: 5518. PMID: 40593538, PMCID: PMC12218103, DOI: 10.1038/s41467-025-60691-8.Peer-Reviewed Original Research
2024
VPS13B is localized at the interface between Golgi cisternae and is a functional partner of FAM177A1
Ugur B, Schueder F, Shin J, Hanna M, Wu Y, Leonzino M, Su M, McAdow A, Wilson C, Postlethwait J, Solnica-Krezel L, Bewersdorf J, De Camilli P. VPS13B is localized at the interface between Golgi cisternae and is a functional partner of FAM177A1. Journal Of Cell Biology 2024, 223: e202311189. PMID: 39331042, PMCID: PMC11451052, DOI: 10.1083/jcb.202311189.Peer-Reviewed Original ResearchCompetition and synergy of Arp2/3 and formins in nucleating actin waves
Le Chua X, San Tong C, Su M, Xǔ X, Xiao S, Wu X, Wu M. Competition and synergy of Arp2/3 and formins in nucleating actin waves. Cell Reports 2024, 43: 114423. PMID: 38968072, PMCID: PMC11378572, DOI: 10.1016/j.celrep.2024.114423.Peer-Reviewed Original ResearchCollective dynamics of actin and microtubule and its crosstalk mediated by FHDC1
San Tong C, Su M, Sun H, Le Chua X, Xiong D, Guo S, Raj R, Ong N, Lee A, Miao Y, Wu M. Collective dynamics of actin and microtubule and its crosstalk mediated by FHDC1. Frontiers In Cell And Developmental Biology 2024, 11: 1261117. PMID: 38567385, PMCID: PMC10985548, DOI: 10.3389/fcell.2023.1261117.Peer-Reviewed Original ResearchUnraveling cellular complexity with transient adapters in highly multiplexed super-resolution imaging
Schueder F, Rivera-Molina F, Su M, Marin Z, Kidd P, Rothman J, Toomre D, Bewersdorf J. Unraveling cellular complexity with transient adapters in highly multiplexed super-resolution imaging. Cell 2024, 187: 1769-1784.e18. PMID: 38552613, PMCID: PMC12135969, DOI: 10.1016/j.cell.2024.02.033.Peer-Reviewed Original Research
2023
PLSCR1 is a cell-autonomous defence factor against SARS-CoV-2 infection
Xu D, Jiang W, Wu L, Gaudet R, Park E, Su M, Cheppali S, Cheemarla N, Kumar P, Uchil P, Grover J, Foxman E, Brown C, Stansfeld P, Bewersdorf J, Mothes W, Karatekin E, Wilen C, MacMicking J. PLSCR1 is a cell-autonomous defence factor against SARS-CoV-2 infection. Nature 2023, 619: 819-827. PMID: 37438530, PMCID: PMC10371867, DOI: 10.1038/s41586-023-06322-y.Peer-Reviewed Original Research
2020
Comparative Study of Curvature Sensing Mediated by F-BAR and an Intrinsically Disordered Region of FBP17
Su M, Zhuang Y, Miao X, Zeng Y, Gao W, Zhao W, Wu M. Comparative Study of Curvature Sensing Mediated by F-BAR and an Intrinsically Disordered Region of FBP17. IScience 2020, 23: 101712. PMID: 33205024, PMCID: PMC7649350, DOI: 10.1016/j.isci.2020.101712.Peer-Reviewed Original Research
2018
Membrane shape-mediated wave propagation of cortical protein dynamics
Wu Z, Su M, Tong C, Wu M, Liu J. Membrane shape-mediated wave propagation of cortical protein dynamics. Nature Communications 2018, 9: 136. PMID: 29321558, PMCID: PMC5762918, DOI: 10.1038/s41467-017-02469-1.Peer-Reviewed Original Research
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