Nabin Koirala
he/him/his
Associate Research Scientist in the Child Study CenterCards
About
Research
Publications
2025
Neuroimaging genetics and developmental psychopathology: A systematic review.
Cheek C, Dobrynin P, Khafizova G, Koirala N, Mahaffy K, Grigorenko E. Neuroimaging genetics and developmental psychopathology: A systematic review. Development And Psychopathology 2025, 1-23. PMID: 40888338, DOI: 10.1017/s0954579425100400.Peer-Reviewed Original ResearchImaging GeneticsBrain imaging phenotypesGenetic basisSocio-emotional developmentDevelopmental psychopathologyBrain structuresEarly adolescenceLate adolescenceNeuroimaging techniquesLate childhoodNeurodevelopmental disordersGenetic dataDevelopmental ageGenetic markersMolecular geneticsAdolescentsBehavior predictionImaging phenotypesChildhoodClinical traitsAnimal studiesPsychopathologyGeneticsNeuroimagingInclusion criteriaAdvancements in invasive and non-invasive neuromodulation for Parkinson’s disease: current findings and future directions
Koirala N, Bange M, Wagle Shukla A, Muthuraman M. Advancements in invasive and non-invasive neuromodulation for Parkinson’s disease: current findings and future directions. Npj Parkinson's Disease 2025, 11: 221. PMID: 40738895, PMCID: PMC12311154, DOI: 10.1038/s41531-025-01071-3.Peer-Reviewed Original ResearchCentral Pathophysiology and Brain Network Changes Related to Camptocormia in Parkinson's Disease
Anjum T, Raethjen J, Ding H, Koirala N, Pryss R, Wolke R, Ip C, Deuschl G, Volkmann J, Margraf N, Muthuraman M. Central Pathophysiology and Brain Network Changes Related to Camptocormia in Parkinson's Disease. Movement Disorders 2025 PMID: 40583364, DOI: 10.1002/mds.30278.Peer-Reviewed Original ResearchCamptocormia patientsParavertebral musclesPartial directed coherence analysisParkinson's diseaseEEG-EMG coherenceBrainstem involvementCentral pathophysiologyHealthy controlsBrainstem activityDirectional coherence analysisPatientsAdvanced PDAbnormal flexionCamptocormiaCoherent sourcesCentral motor networkSubcortical regionsDiseaseMuscleTomographic mapsStooped postureBrain network changesCentral musclesBrainInteraction strengthAssistive Artificial Intelligence in Epilepsy and Its Impact on Epilepsy Care in Low- and Middle-Income Countries
Koirala N, Adhikari S, Adhikari M, Yadav T, Anwar A, Ciolac D, Shrestha B, Adhikari I, Khanal B, Muthuraman M. Assistive Artificial Intelligence in Epilepsy and Its Impact on Epilepsy Care in Low- and Middle-Income Countries. Brain Sciences 2025, 15: 481. PMID: 40426652, PMCID: PMC12110662, DOI: 10.3390/brainsci15050481.Peer-Reviewed Original ResearchDisability Adjusted Life YearsMiddle-income countriesEpilepsy careTreatment gapLow-and-middle-income countriesAnd Middle-Income CountriesImproving epilepsy careCost of epilepsyAdjusted Life YearsSignificant financial burdenLMICsMedical specialistsLife yearsCareDisproportionate prevalenceCommunity engagementFinancial burdenGross national productBurdenSocioeconomic impactTreatment approachesHow does SES influence the brain circuitry for literacy? Modeling the association between SES, oral language, white matter integrity, and reading
Villa M, Koirala N, Perdue M, Branum-Martin L, Landi N. How does SES influence the brain circuitry for literacy? Modeling the association between SES, oral language, white matter integrity, and reading. Developmental Cognitive Neuroscience 2025, 73: 101561. PMID: 40319671, PMCID: PMC12099765, DOI: 10.1016/j.dcn.2025.101561.Peer-Reviewed Original ResearchConceptsWhite matter integrityOral languageSocioeconomic statusOral language skillsWhite matter tractsEffect of socioeconomic statusNeurobiological factorsBrain circuitryContribution of socioeconomic statusStructural equation modelingLanguage skillsInfluence readingEducational objectivesLanguageOccupational successParental educationSkill variationReadingEquation modelingContribution of environmental factorsNeurobiologyLiteracyEducationIndirect contributionSkillsThe neural characteristics influencing literacy outcome in children with cochlear implants
Koirala N, Manning J, Neumann S, Anderson C, Deroche M, Wolfe J, Pugh K, Landi N, Muthuraman M, Gracco V. The neural characteristics influencing literacy outcome in children with cochlear implants. Brain Communications 2025, 7: fcaf086. PMID: 40046341, PMCID: PMC11881800, DOI: 10.1093/braincomms/fcaf086.Peer-Reviewed Original ResearchCochlear implantationHearing interventionDuration of deafnessCongenital hearing lossQuality of lifeHearing aidsHearing ageHearing lossImpact of early auditory deprivationAuditory deprivationAuditory developmentFunctional Near-Infrared SpectroscopyTiming of interventionClinical measuresEarly auditory deprivationInterventionEarly interventionAdequate accessHearingReading outcomesReading abilityNeural characteristicsEnhanced outcomesInitial implantationNeural reorganization
2024
Navigating neural pathways: how stimulation polarity shapes deep brain stimulation efficacy
Asadi A, Koirala N, Muthuraman M. Navigating neural pathways: how stimulation polarity shapes deep brain stimulation efficacy. Brain Communications 2024, 7: fcaf061. PMID: 39980738, PMCID: PMC11839837, DOI: 10.1093/braincomms/fcaf061.Peer-Reviewed Original ResearchCross-modal plasticity in children with cochlear implant: converging evidence from EEG and functional near-infrared spectroscopy
Deroche M, Wolfe J, Neumann S, Manning J, Hanna L, Towler W, Wilson C, Bien A, Miller S, Schafer E, Gemignani J, Alemi R, Muthuraman M, Koirala N, Gracco V. Cross-modal plasticity in children with cochlear implant: converging evidence from EEG and functional near-infrared spectroscopy. Brain Communications 2024, 6: fcae175. PMID: 38846536, PMCID: PMC11154148, DOI: 10.1093/braincomms/fcae175.Peer-Reviewed Original ResearchCochlear implantationImplanted childrenCross-modal reorganizationYear old childrenAuditory association areasFunctional Near-Infrared SpectroscopyCross-modal plasticitySilent worldNear-infrared spectroscopyVisual cortex responsesAuditory cortexCortical responsesOlder childrenResponse to environmental stimulationPromote visionsChildrenHigh-density electroencephalographyImplantationCortex responsesLow-level visual tasksVisual cortexHearingCortexAssociation areasLanguage ability
2023
Brain connectivity networks underlying resting heart rate variability in acute ischemic stroke
Dimova V, Welte-Jzyk C, Kronfeld A, Korczynski O, Baier B, Koirala N, Steenken L, Kollmann B, Tüscher O, Brockmann M, Birklein F, Muthuraman M. Brain connectivity networks underlying resting heart rate variability in acute ischemic stroke. NeuroImage Clinical 2023, 41: 103558. PMID: 38142520, PMCID: PMC10788522, DOI: 10.1016/j.nicl.2023.103558.Peer-Reviewed Original ResearchHeart rate variabilityAcute strokeLesion patternsStroke lesionsSex-matched normal subjectsAge-matched healthy subjectsLF powerRate variabilityAcute ischemic strokeAcute stroke patientsAcute stroke lesionsAnalysis of HRVResting-state brain networksDefault mode networkIschemic strokeStroke patientsVentral attention networkDiffusion-weighted imagesHRV alterationsSupine positionHealthy subjectsNormal subjectsBrain areasBrain regionsHRV parametersAudiovisual integration in children with cochlear implants revealed through EEG and fNIRS
Alemi R, Wolfe J, Neumann S, Manning J, Towler W, Koirala N, Gracco V, Deroche M. Audiovisual integration in children with cochlear implants revealed through EEG and fNIRS. Brain Research Bulletin 2023, 205: 110817. PMID: 37989460, DOI: 10.1016/j.brainresbull.2023.110817.Peer-Reviewed Original ResearchHigher language abilityLow language abilityAV stimuliCochlear implantsLanguage abilityNormal hearingAudio-visual modesSchool-aged childrenAV integrationAudiovisual integrationNH childrenMultimodal processingAV stimulationAuditory regionsEEG metricsAuditory-evoked potentialsVisual informationVisual-evoked potentialsBetter languageGroup differencesCortical responsesSingle speakerSensory deprivationOccipital regionEEG data
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Child Study Center
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New Haven, CT 06511
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New Haven, CT 06511