Voluntary faculty are typically clinicians or others who are employed outside of the School but make significant contributions to department programs at the medical center or at affiliate institutions.
Voluntary rank detailsDavid Saunders, MD, PhD
Assistant Clinical ProfessorAbout
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Titles
Solnit Integrated Training Program, Yale Child Study Center
Biography
Dr. Saunders obtained his MD from Cornell and PhD in Buddhist Studies at Emory. His dissertation, entitled "Self and Non-Self in Mindfulness-Based Stress Reduction", was completed under the mentorship of Dr. John Dunne. In the Solnit Integrated Training program, he is developing a clinical trial investigating a novel mindfulness-based intervention for elementary-school children with ADHD with Dr. Hedy Kober.
Appointments
Child Study Center
Assistant Clinical ProfessorPrimary
Other Departments & Organizations
Education & Training
- PhD
- Emory University (2015)
- MD
- Weill Cornell Medical College (2014)
- BA
- Boston College (2007)
Research
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Overview
David Saunders, MD, PhD attended Boston College as an undergraduate, majoring in theology. He spent four months living in a Tibetan refugee community in Kathmandu, Nepal, where he studied the history and philosophy of Tibetan Buddhism. After graduating from Boston College in 2007, David returned to the same Tibetan community in Nepal as a Fulbright Scholar, studying Tibetan religio-cultural perceptions of tuberculosis, which confirmed his desire to pursue a PhD in Buddhist studies alongside medical training. From 2008 to 2015, he matriculated at Weill Cornell Medical School (WCMC) and obtained a PhD in Religion at Emory University under John Dunne, with a specific focus on Buddhist meditation theory and the philosophy of mind and self. For the last several years, he has taught mindfulness and compassion-based meditation in various settings—especially enjoying his time with children and teenagers. He is presently a clinical and research fellow in the Albert J. Solnit Integrated Training Program at the Yale Child Study Center at Yale University. He is currently running a small clinical trial of a novel mindfulness-based intervention for elementary school children with ADHD under the mentorship of Hedy Kober.
Medical Research Interests
ORCID
0000-0003-0946-1164
Research at a Glance
Publications Timeline
Publications
2025
Long COVID and the Military: A Current Research Landscape, Knowledge Gaps, and Future Directions
Pollett S, Agan B, Letizia A, Richard S, Porter C, Epsi N, Haigney M, Saunders D, Colombo R, Burgess T, Morris M, Tribble D, La Croix C, Jones M, O’Connell R. Long COVID and the Military: A Current Research Landscape, Knowledge Gaps, and Future Directions. Military Medicine 2025, usaf343. PMID: 40748784, DOI: 10.1093/milmed/usaf343.Peer-Reviewed Original ResearchAltmetricConceptsMilitary service membersService membersRisk factors associated with Long CovidFactors associated with Long COVIDMilitary Health SystemLong COVIDActive duty personnelPost-acute sequelaeHealth systemMental healthPost-COVID conditionsMilitary healthMilitary readinessOverall healthDuty personnelMilitary populationActive dutyConference abstractsImpact of long COVIDResearch prioritiesNarrative reviewHealthCardiorespiratoryFunctional impactPublished articlesComparative cohort study of post-acute COVID-19 infection with a nested, randomized controlled trial of ivabradine for those with postural orthostatic tachycardia syndrome (the COVIVA study)
Saunders D, Arnold T, Lavender J, Bi D, Alcover K, Hellwig L, Leazer S, Mohammed R, Markos B, Perera K, Shaw D, Kobi P, Evans M, Mains A, Tanofsky-Kraff M, Goguet E, Mitre E, Pratt K, Dalgard C, Haigney M. Comparative cohort study of post-acute COVID-19 infection with a nested, randomized controlled trial of ivabradine for those with postural orthostatic tachycardia syndrome (the COVIVA study). Frontiers In Neurology 2025, 16: 1550636. PMID: 40692561, PMCID: PMC12278775, DOI: 10.3389/fneur.2025.1550636.Peer-Reviewed Original ResearchCitationsAltmetricConceptsPostural orthostatic tachycardia syndromeInappropriate sinus tachycardiaOrthostatic tachycardia syndromeRisk factorsAutonomic dysfunctionMulti-omics analysisIndicators of metabolic dysfunctionPersistent immune activationEffects of ivabradinePlacebo-controlled trialComparative cohort studyManagement of tachycardiaImpact of ivabradineAssessed non-invasivelyRandomized Controlled TrialsDocumented COVID-19Chest painBlurred visionOptimal therapyBeta blockersSinus tachycardiaImmune activationCOVID-19 infectionHeart failureInflammatory biomarkersSafety and immunogenicity of an adjuvanted chikungunya virus virus-like particle (CHIKV VLP) vaccine in previous recipients of other alphavirus vaccines versus alphavirus vaccine-naive controls: an open-label, parallel-group, age-matched, sex-matched, phase 2 randomised controlled study
Hamer M, McCarty J, Pierson B, Regules J, Mendy J, Sanborn A, Gardner C, Haller J, Gregory M, Liggett D, Glass P, Ghosh N, Royalty Tredo S, Warfield K, Burke C, Lee C, Saunders D, Bedell L, Richardson J. Safety and immunogenicity of an adjuvanted chikungunya virus virus-like particle (CHIKV VLP) vaccine in previous recipients of other alphavirus vaccines versus alphavirus vaccine-naive controls: an open-label, parallel-group, age-matched, sex-matched, phase 2 randomised controlled study. The Lancet Microbe 2025, 6: 101000. PMID: 39954701, DOI: 10.1016/j.lanmic.2024.101000.Peer-Reviewed Original ResearchCitationsAltmetricConceptsGeometric mean titresCHIKV VLPsVaccine recipientsVLP vaccineAdverse eventsSex-matchedAlphavirus vaccinesOpen-labelParallel-groupAge-matchedVirus-like particlesPrimary immunogenicity endpointNeutralising antibodiesVEEV vaccinesAntibody seroconversion ratesPhase 2 randomised controlled trialFisher's exact testClinical study sitesStatistically significant differenceImmunogenicity endpointsSeroconversion ratesCompare immunogenicitySingle doseAntibody increaseExact testP-1980. Decoding the Complexity of Post COVID Conditions: Transcriptomic Analyses of Machine-Learning-Based Chronic Symptom Phenotypes
Epsi N, Chenoweth J, Richard S, Lindholm D, Mende K, Ganesan A, Lalani T, Colombo R, Larson D, Berjohn C, Saunders D, Simons M, O’Connell R, Tribble D, Agan B, Burgess T, Dalgard C, Pollett S. P-1980. Decoding the Complexity of Post COVID Conditions: Transcriptomic Analyses of Machine-Learning-Based Chronic Symptom Phenotypes. Open Forum Infectious Diseases 2025, 12: ofae631.2138. PMCID: PMC11779332, DOI: 10.1093/ofid/ofae631.2138.Peer-Reviewed Original ResearchAltmetricConceptsMilitary Health SystemMilitary Health System beneficiariesPost-COVID conditionsSymptom clustersNormalized enrichment scorePathway enrichment analysisTranscriptome analysisMilitary health concernSARS-CoV-2 positive testSurvey 3 monthsTranscriptome profilingEnrichment analysisHealth systemSymptom prevalenceSymptom-clustersPre-existing illnessGene expression pathwaysCohort studyGroups of participantsDemographic characteristicsNervous system developmentSystem beneficiariesSymptom dataMYC targets v1Health concern
2024
Comparing the clinical utility of pharmacogenomic genotyping and next generation sequencing in a military health system adult medicine clinic
Saunders D, Hellwig L, Pagani A, De Castro M, Haigney M, Poon L, Ehat N, Heroy A, Libbus J, Fox K, Kalra S, Arnold T, Turner C, Black J, Scherer S, Moyer A. Comparing the clinical utility of pharmacogenomic genotyping and next generation sequencing in a military health system adult medicine clinic. Pharmacogenomics 2024, 25: 637-645. PMID: 39981562, PMCID: PMC11901368, DOI: 10.1080/14622416.2025.2466413.Peer-Reviewed Original ResearchAltmetricMeSH Keywords and ConceptsConceptsNext-generation sequencing panelDrug-drug interactionsNext generation sequencingPGx variantsPharmacogenomic genotypingCPIC guidelinesMilitary Health SystemGeneration sequencingReduce adverse drug reactionsPotential drug-drug interactionsNG-TestSequencing panelGenotyping assayAdult medicine clinicAdverse drug reactionsPGxCross-sectional studyGenotypesNGS resultsScreening optionsDrug efficacyDrug reactionsClinical utilityMedicine clinicPrevent adverse effectsN‐acetylcysteine as a treatment for substance use cravings: A meta‐analysis
Winterlind E, Malone S, Setzer M, Murphy M, Saunders D, Gray J. N‐acetylcysteine as a treatment for substance use cravings: A meta‐analysis. Addiction Biology 2024, 29: e70001. PMID: 39556483, PMCID: PMC11572739, DOI: 10.1111/adb.70001.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsSubstance use disordersNAC efficacySubstance cravingRisk of biasPublication biasRandomized Controlled TrialsSubstance use cravingSymptoms of cravingMeta-analysisMeta-analytic outcomesMeta-analysesN-acetylcysteineEfficacy of N-acetylcysteineCraving symptomsRisk of bias assessmentPresence of publication biasUse disorderDatabase search of PubMedImpact of N-acetylcysteineAdverse eventsCravingLeave-one-out analysisFunnel plot testSubstance useDatabase searchClinical Characteristics and Outcomes of Cardiac Findings in Young Persons Following SARS-CoV-2 Infection
Jones M, Richard S, Malloy A, Colombo R, May J, Saunders D, Lindholm D, Ganesan A, Sablak C, Hickey P, Dobson C, Pollett S, Flanagan R, Group O. Clinical Characteristics and Outcomes of Cardiac Findings in Young Persons Following SARS-CoV-2 Infection. The Pediatric Infectious Disease Journal 2024, 44: 342-345. PMID: 40063968, DOI: 10.1097/inf.0000000000004617.Peer-Reviewed Original ResearchMeSH Keywords and ConceptsConceptsRoutine cardiac screeningMild COVID-19 casesSARS-CoV-2 infectionCardiac complicationsCardiac findingsCardiac symptomsCardiac screeningClinical characteristicsCardiac abnormalitiesProspective cohortSevere acute respiratory syndrome coronavirus 2Acute respiratory syndrome coronavirus 2Respiratory syndrome coronavirus 2Syndrome coronavirus 2SARS-CoV-2Coronavirus 2Young personPerformance of rapid antigen tests to detect SARS-CoV-2 variant diversity and correlation with viral culture positivity: implication for diagnostic development and future public health strategies
Goux H, Green J, Wilson A, Sozhamannan S, Richard S, Colombo R, Lindholm D, Jones M, Agan B, Larson D, Saunders D, Mody R, Cox J, Deans R, Walish J, Fries A, Simons M, Pollett S, Smith D. Performance of rapid antigen tests to detect SARS-CoV-2 variant diversity and correlation with viral culture positivity: implication for diagnostic development and future public health strategies. MBio 2024, 15: e02737-24. PMID: 39480114, PMCID: PMC11633148, DOI: 10.1128/mbio.02737-24.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsPerformance of Ag-RDTSARS-CoV-2 variantsAg-RDTs resultsRapid diagnostic testsAntigen-based rapid diagnostic testAg-RDTCulture-based resultsSARS-CoV-2Culture positivityDiagnostic testsPerformance of rapid antigen testsAg-RDT sensitivityApparent trade-offPCR-positive infectionsViral culture positivityN proteinRapid antigen testModerate to high sensitivityVariant diversityAntigen-based testsRisk of transmissionVirus-positiveMolecular assaysAntigen testRespiratory pathogensEstimating the Effect of Coronavirus Disease 2019 (COVID-19) Vaccination and Infection Variant on Post-COVID-19 Venous Thrombosis or Embolism Risk
O'Carroll A, Richard S, Byrne C, Rusiecki J, Wier B, Berjohn C, Fries A, Lalani T, Smith A, Mody R, Ganesan A, Huprikar N, Colombo R, Schofield C, Lindholm D, Mende K, Jones M, Flanagan R, Larson D, Ewers E, Saunders D, Maves R, Maldonado C, Sanchez Edwards M, O'Connell R, Simons M, Tribble D, Agan B, Burgess T, Pollett S. Estimating the Effect of Coronavirus Disease 2019 (COVID-19) Vaccination and Infection Variant on Post-COVID-19 Venous Thrombosis or Embolism Risk. Open Forum Infectious Diseases 2024, 11: ofae557. PMID: 39494453, PMCID: PMC11530954, DOI: 10.1093/ofid/ofae557.Peer-Reviewed Original ResearchCitationsAltmetricConceptsCase-control studySARS-CoV-2 infectionMilitary Health SystemVenous thrombosisMilitary Health System beneficiariesVTE risk factorsSARS-CoV-2COVID-19 vaccineMultivariate logistic regressionDays of SARS-CoV-2 infectionPost-coronavirus diseaseTime of infectionVTE diagnosisPositive SARS-CoV-2 testVTE riskRisk reductionSevere acute respiratory syndrome coronavirus 2Acute respiratory syndrome coronavirus 2Incident VTEEffectiveness of COVID-19 vaccinesSARS-CoV-2 testingVaccine seriesEmbolic riskRespiratory syndrome coronavirus 2Immune and behavioral correlates of protection against symptomatic post-vaccination SARS-CoV-2 infection
Goguet E, Olsen C, Meyer W, Ansari S, Powers J, Conner T, Coggins S, Wang W, Wang R, Illinik L, Edwards M, Jackson-Thompson B, Hollis-Perry M, Wang G, Alcorta Y, Wong M, Saunders D, Mohammed R, Balogun B, Kobi P, Kosh L, Bishop-Lilly K, Cer R, Arnold C, Voegtly L, Fitzpatrick M, Luquette A, Malagon F, Ortega O, Parmelee E, Davies J, Lindrose A, Haines-Hull H, Moser M, Samuels E, Rekedal M, Graydon E, Malloy A, Tribble D, Burgess T, Campbell W, Robinson S, Broder C, O’Connell R, Weiss C, Pollett S, Laing E, Mitre E. Immune and behavioral correlates of protection against symptomatic post-vaccination SARS-CoV-2 infection. Frontiers In Immunology 2024, 15: 1287504. PMID: 38566991, PMCID: PMC10985347, DOI: 10.3389/fimmu.2024.1287504.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsResearch assaySARS-CoV-2Commercial assaysIgA binding antibodiesCorrelates of protectionAnti-spike IgG levelsSpike-specific IgGShorter duration of illnessDuration of illnessMultivariate regression analysisSARS-CoV-2 infectionShort durationSARS-CoV-2 variantsNeutralization titersPost-vaccination SARS-CoV-2 infectionIgG levelsNeutralizing activityOmicron waveBehavioral correlatesRisk scoreDisease severityBinding antibodiesSerumSaliva samplesOmicron subvariants