Child Study Center Grand Rounds: Progress in Biomarker Development in Autism Spectrum Disorder

Participant characterization and selection for research and clinical trials relies on subjective clinical assessments and caregiver report measures. There is a critical need for objective and sensitive measures to quantify social and communicative characteristics in ASD for the purposes of predicting response to intervention, measuring treatment outcomes, and stratifying a heterogeneous population into more homogenous subgroups. The discussion will review ongoing research in the McPartland Lab and the Autism Biomarkers Consortium for Clinical trials designed to evaluate feasibility of electrophysiological and eye-tracking biomarkers to address these needs. Attendees will learn the state of biomarker science in ASD, the clinical importance of biomarker development, and strategies to advance this line of inquiry.