Jessica Nouws, PhD
Associate Research Scientist; EMBO fellow
Research & Publications
Biography
News
Coauthors
Selected Publications
- Alterations in adipose tissue distribution, cell morphology and function mark primary insulin hypersecretion in youths with obesity.Tricò D, Chiriacò M, Nouws J, Vash-Margita A, Kursawe R, Tarabra E, Galderisi A, Natali A, Giannini C, Hellerstein M, Ferrannini E, Caprio S. Alterations in adipose tissue distribution, cell morphology and function mark primary insulin hypersecretion in youths with obesity. Diabetes 2023 PMID: 37870826, DOI: 10.2337/db23-0450.
- Reduced Alveolar Type 2 Epithelial Expression of NUPR1 Is Associated with Severe COPD and Increases Susceptibility to Oxidative Stress and FerroptosisNouws J, Mcdonough J, Adams T, Werder R, Schupp J, Robertson M, Coarfa C, Poli De Frias S, Wilson A, Timshel P, Kaminski N, Rosas I, Sauler M. Reduced Alveolar Type 2 Epithelial Expression of NUPR1 Is Associated with Severe COPD and Increases Susceptibility to Oxidative Stress and Ferroptosis. 2022, a1040-a1040. DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1040.
- The Role of CD74 in Bleomycin-Induced Pulmonary FibrosisYang T, Kim S, Leng L, Nouws J, Bucala R, Sauler M. The Role of CD74 in Bleomycin-Induced Pulmonary Fibrosis. 2022, a5334-a5334. DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a5334.
- Decreased NUPR1 in AT2 Cells Is Associated with Development of Emphysema in COPDMcDonough J, Adams T, Kothapalli N, Schupp J, Nouws J, Chioccioli M, Omote N, Cosme Jr. C, Poli De Frias S, Ayaub E, Chu S, Jensen K, Gomez J, Britto-Leon C, Raredon M, Niklason L, Timshel P, Kaminski N, Rosas I, Sauler M. Decreased NUPR1 in AT2 Cells Is Associated with Development of Emphysema in COPD. 2021, a4281-a4281. DOI: 10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a4281.
- Protective Role of D-Dopachrome Tautomerase (MIF2) in Chronic Obstructive Pulmonary DiseaseArdito T, Nouws J, Kim S, Zhang Y, Bucala R, Lee P, Sauler M. Protective Role of D-Dopachrome Tautomerase (MIF2) in Chronic Obstructive Pulmonary Disease. 2019, a5374-a5374. DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a5374.
- MicroRNA Regulation of Cell Fate in the Pathogenesis of COPDSauler M, Nouws J, Feng W, Lee P. MicroRNA Regulation of Cell Fate in the Pathogenesis of COPD. 2019, a5375-a5375. DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a5375.
- Ethnicity and Common Genetic Variants Modulate Nonalcoholic Fatty Liver Disease (NAFLD) Metabolic Phenotype in Obese YouthTRICO D, CAPRIO S, UMANO G, GALDERISI A, MATA M, NOUWS J, PIERPONT B, KIM G, SANTORO N. Ethnicity and Common Genetic Variants Modulate Nonalcoholic Fatty Liver Disease (NAFLD) Metabolic Phenotype in Obese Youth. Diabetes 2018, 67 DOI: 10.2337/db18-313-or.
- A Role of the Inflammasome in the Low Storage Capacity of the Abdominal Subcutaneous Adipose Tissue in Obese AdolescentsKursawe R, Dixit VD, Scherer PE, Santoro N, Narayan D, Gordillo R, Giannini C, Lopez X, Pierpont B, Nouws J, Shulman GI, Caprio S. A Role of the Inflammasome in the Low Storage Capacity of the Abdominal Subcutaneous Adipose Tissue in Obese Adolescents. Diabetes 2015, 65: 610-618. PMID: 26718495, PMCID: PMC4764142, DOI: 10.2337/db15-1478.
- ACAD9, a complex I assembly factor with a moonlighting function in fatty acid oxidation deficienciesNouws J, Brinke H, Nijtmans L, Houten S. ACAD9, a complex I assembly factor with a moonlighting function in fatty acid oxidation deficiencies. Human Molecular Genetics 2013, 23: 1311-1319. PMID: 24158852, DOI: 10.1093/hmg/ddt521.
- A Patient with Complex I Deficiency Caused by a Novel ACAD9 Mutation Not Responding to Riboflavin TreatmentNouws J, Wibrand F, van den Brand M, Venselaar H, Duno M, Lund A, Trautner S, Nijtmans L, Østergard E. A Patient with Complex I Deficiency Caused by a Novel ACAD9 Mutation Not Responding to Riboflavin Treatment. 2013, 12: 37-45. PMID: 23996478, PMCID: PMC3897792, DOI: 10.1007/8904_2013_242.
- 3‐Methylglutaconic aciduria—lessons from 50 genes and 977 patientsWortmann S, Kluijtmans L, Rodenburg R, Sass J, Nouws J, van Kaauwen E, Kleefstra T, Tranebjaerg L, de Vries M, Isohanni P, Walter K, Alkuraya F, Smuts I, Reinecke C, van der Westhuizen F, Thorburn D, Smeitink J, Morava E, Wevers R. 3‐Methylglutaconic aciduria—lessons from 50 genes and 977 patients. Journal Of Inherited Metabolic Disease 2013, 36: 913-921. PMID: 23355087, DOI: 10.1007/s10545-012-9579-6.
- The Assembly of Human Complex INouws J, Calvaruso M, Nijtmans L. The Assembly of Human Complex I. 2012, 193-217. DOI: 10.1007/978-94-007-4138-6_10.
- Assembly factors as a new class of disease genes for mitochondrial complex I deficiency: cause, pathology and treatment optionsNouws J, Nijtmans L, Smeitink J, Vogel R. Assembly factors as a new class of disease genes for mitochondrial complex I deficiency: cause, pathology and treatment options. Brain 2011, 135: 12-22. PMID: 22036961, DOI: 10.1093/brain/awr261.
- NDUFB7 and NDUFA8 are located at the intermembrane surface of complex ISzklarczyk R, Wanschers B, Nabuurs S, Nouws J, Nijtmans L, Huynen M. NDUFB7 and NDUFA8 are located at the intermembrane surface of complex I. FEBS Letters 2011, 585: 737-743. PMID: 21310150, DOI: 10.1016/j.febslet.2011.01.046.
- Acyl-CoA Dehydrogenase 9 Is Required for the Biogenesis of Oxidative Phosphorylation Complex INouws J, Nijtmans L, Houten S, van den Brand M, Huynen M, Venselaar H, Hoefs S, Gloerich J, Kronick J, Hutchin T, Willems P, Rodenburg R, Wanders R, van den Heuvel L, Smeitink J, Vogel R. Acyl-CoA Dehydrogenase 9 Is Required for the Biogenesis of Oxidative Phosphorylation Complex I. Cell Metabolism 2010, 12: 283-294. PMID: 20816094, DOI: 10.1016/j.cmet.2010.08.002.