Uma Reddy, MD, MPH
Mary Lake Polan, MD, PhD, MPH Professor of Obstetrics, Gynecology & Reproductive SciencesCards
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Titles
Mary Lake Polan, MD, PhD, MPH Professor of Obstetrics, Gynecology & Reproductive Sciences
Executive Vice Chair, Department of Obstetrics, Gynecology & Reproductive Sciences, Obstetrics, Gynecology & Reproductive Sciences; Affiliated Faculty, Yale Institute for Global Health
Biography
Uma M. Reddy, MD, MPH, is a nationally and internationally recognized maternal-fetal medicine specialist, clinician-scientist, and leader in academic medicine who has devoted more than two decades to advancing research aimed at improving outcomes for women and infants. Her areas of expertise include stillbirth, preterm birth, labor management, and maternal health.
Reddy graduated magna cum laude with a bachelor’s in biology from Brown University and earned her MD from the Warren Alpert Medical School of Brown University. She received a Master of Public Health degree from the Johns Hopkins Bloomberg School of Public Health, completed her residency in obstetrics and gynecology at The Johns Hopkins Hospital, and subsequently completed fellowship training in maternal-fetal medicine at Thomas Jefferson University in Philadelphia, Pennsylvania.
During her 15 years at the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) at the National Institutes of Health (NIH), Reddy oversaw many of the nation's most influential obstetric research initiatives, including the Maternal-Fetal Medicine Units (MFMU) Network. She also served as project scientist for major collaborative studies, including the Stillbirth Collaborative Research Network, the Genomics and Proteomics Network for Preterm Birth Research, and the Nulliparous Pregnancy Outcomes Study: Monitoring Mothers-to-Be (nuMoM2b).
Reddy joined Yale School of Medicine in 2018 as professor and chief of maternal-fetal medicine, where she led multiple NIH-funded studies, including the GO MOMs study, and was selected for the prestigious Executive Leadership in Academic Medicine (ELAM) program. From 2022 to 2025, she served as the Virgil G. Damon Professor and vice chair of research at Columbia University Vagelos College of Physicians and Surgeons and professor of population and family health at the Mailman School of Public Health, where she led several major NIH-funded initiatives focused on maternal health.
In 2026, Reddy returned to Yale as the Mary Lake Polan, MD, PhD, MPH, Professor of Obstetrics, Gynecology and Reproductive Sciences and executive vice chair of the Department of Obstetrics, Gynecology and Reproductive Sciences.
She has authored more than 400 peer-reviewed publications and has played a key role in developing national obstetric guidelines through the American College of Obstetricians and Gynecologists. In recognition of her transformative contributions to obstetric research, she was elected to the National Academy of Medicine in 2024.
Reddy is board certified in obstetrics and gynecology and maternal-fetal medicine. Her clinical expertise includes the management of high-risk pregnancies complicated by prior pregnancy loss, preterm birth, diabetes, hypertension, and other maternal medical conditions.
Departments & Organizations
- Improving Clinical Care for Recurrent Pregnancy Loss
- Yale Center for Genomic Health
- Yale Medicine
- Yale New Haven Health System
Education & Training
- Fellow
- Thomas Jefferson University (2000)
- MPH
- Johns Hopkins Bloomberg School of Public Health, Biostatistics (1999)
- Robert Wood Johnson Clinical Scholar
- Johns Hopkins University (1997)
- Resident
- Johns Hopkins Hospital (1995)
- Intern
- Johns Hopkins Hospital (1992)
- MD
- The Warren Alpert Medical School of Brown University (1991)
- ScB
- Brown University, Biology (1988)
Research
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Overview
Medical Research Interests
Public Health Interests
ORCID
0000-0001-5519-1527
Research at a Glance
Yale Co-Authors
Publications Timeline
Research Interests
Audrey Merriam, MD, MS
Heping Zhang, PhD
Jennifer Sherr, MD, PhD
Lisbet Lundsberg, PhD
Jennifer Culhane
Lena Sweeney, MD, BS
Pregnant People
Publications
2026
The Association of the Social Vulnerability Index with Acuity of Presentation to Obstetric Triage
Bank T, Sandoval G, Saade G, Varner M, Tita A, Longo M, Bell E, Stoll B, Thorp J, Reddy U, Costantine M, Grobman W, Rouse D, Simhan H, Bailit J, Parry S, Sibai B. The Association of the Social Vulnerability Index with Acuity of Presentation to Obstetric Triage. American Journal Of Perinatology 2026 PMID: 42208579, DOI: 10.1055/a-2883-6655.Peer-Reviewed Original ResearchConceptsCommunity-level social determinants of healthSocial determinants of healthDeterminants of healthAdverse social determinantsObstetric triageBody mass indexAcuity of presentationAdverse social determinants of healthSocial Vulnerability IndexAssociated with acuityMulti-site cohort studyCDC-SVIHigher Body Mass IndexPregnancy outcomesAdverse perinatal outcomesAssociated with adverse pregnancy outcomesAdverse pregnancy outcomesTobacco useTriage visitsPrimary exposureSecondary analysisClinical acuityCohort studyMaternal ageMass indexEarly Pregnancy Glycemic Testing for Prediction of Gestational Diabetes Mellitus and Large for Gestational Age Birth Weight.
LeBlanc E, Vesco K, Amy D, Massimino S, Price J, Robinson S, Schell K, Davis L, Holness T, Hillier T, Oshiro C, Cordero S, Howick C, Kim L, Martinez Y, Pishchalenko O, Wastlova V, Zork N, Mourad M, Lonier J, Reddy U, Acevedo J, Castillo J, Gomez M, Peguero B, Perez Y, Facco F, Feghali M, Bocan H, Stramowski S, Powe C, Catalano P, Edlow A, Barth W, Nathan D, Larkin M, Maya J, Azevedo R, Baez A, Iroajanma C, Michalopoulos C, Neamonitaki N, Thangthaeng N, Yee L, Lowe W, Grobman W, Szmuilowicz E, Aguirre A, Mallett G, Matos S, Tyagi S, Uribe I, Spadola A, Azimirad A, Werner E, Rouse D, Malloy M, Parra F, Moniz C, Sherr J, Merriam A, Bitterman S, Considine E, Leventhal J, Perley L, Rink L, Steffen A, Thompson B, Zgorski M, Steffes M, Arends V, Killeen A, Scholtens D, Siddique J, Bustamante P, Cheung Y, Grott T, Kuang A, Tull M, Guachichullca J. Early Pregnancy Glycemic Testing for Prediction of Gestational Diabetes Mellitus and Large for Gestational Age Birth Weight. Diabetes Care 2026 PMID: 42251767, DOI: 10.2337/dc26-0302.Peer-Reviewed Original ResearchConceptsOral glucose tolerance testGestational diabetes mellitusPositive predictive valueNegative predictive valueClinical factorsWeeks gestationContinuous glucose monitoringPregnancy oral glucose tolerance testDiabetes mellitusGestational age birth weightPrediction of gestational diabetes mellitusGestational diabetes mellitus prevalencePredictive valueProspective observational studyReceiver operating characteristic curveArea under the receiver operating characteristic curveGlucose tolerance testOperating characteristics curveSingleton gestationsGestational ageGDM prevalenceGlycemic criteriaPregnancy outcomesBirth weightLive births1232-OR: Dynamic CGM Models to Predict GDM: A GO MOMs Analysis
SIDDIQUE J, SHERR J, CATALANO P, FACCO F, FEGHALI M, GROBMAN W, LEBLANC E, LONIER J, LOWE W, MERRIAM A, MOURAD M, OSHIRO C, POWE C, REDDY U, ROUSE D, SCHOLTENS D, SPADOLA A, VESCO K, WERNER E, YEE L, ZORK N, LANCKI N, SZMUILOWICZ E. 1232-OR: Dynamic CGM Models to Predict GDM: A GO MOMs Analysis. Diabetes 2026, 75 DOI: 10.2337/db26-1232-or.Peer-Reviewed Original ResearchConceptsInfant hospitalizationCGM metricsGDM predictionInfants Hospital of Rhode IslandCarpenter-Coustan criteriaPre-existing diabetesMulticenter observational studyAmerican Diabetes AssociationNational InstituteDigestive and Kidney DiseasesCarpenter-CoustanSingleton gestationsMassachusetts General HospitalClinical predictorsEarly pregnancyGDM outcomesMaternal ageClinical factorsClinical dataNational Institutes of HealthGDMKidney diseasePredicting GDMClinical relevanceObservational study1234-OR: Do First-Trimester Metabolic or Lipid Measures Improve Prediction of GDM and LGA?
LEBLANC E, KUANG A, FACCO F, FEGHALI M, GROBMAN W, KILLEEN A, LOWE W, MERRIAM A, MOURAD M, OSHIRO C, POWE C, REDDY U, ROUSE D, SHERR J, SPADOLA A, VESCO K, WERNER E, YEE L, ZORK N, SCHOLTENS D, CATALANO P. 1234-OR: Do First-Trimester Metabolic or Lipid Measures Improve Prediction of GDM and LGA? Diabetes 2026, 75 DOI: 10.2337/db26-1234-or.Peer-Reviewed Original ResearchConceptsPrediction of GDMClinical factorsLipid measurementsInfant hospitalizationPrediction of gestational diabetesInfants Hospital of Rhode IslandCarpenter-Coustan criteriaFirst-trimester screeningMetabolic measuresReceiver operating characteristic curveAmerican Diabetes AssociationNational InstituteDigestive and Kidney DiseasesOperating characteristics curveCarpenter-CoustanOGTT valuesSingleton gravidasWeeks gestationGestational diabetesMassachusetts General HospitalFirst-trimesterEarly pregnancyLive birthsLogistic regression modelsUS Centers1235-OR: Gestational Diabetes Diagnosis Using Continuous Glucose Monitoring at 24–28 Weeks’ Gestation
MERRIAM A, BANKER M, CATALANO P, FACCO F, FEGHALI M, GROBMAN W, LEBLANC E, LOWE W, MOURAD M, OSHIRO C, POWE C, REDDY U, ROUSE D, SCHOLTENS D, SHERR J, SPADOLA A, VESCO K, WERNER E, ZORK N, YEE L. 1235-OR: Gestational Diabetes Diagnosis Using Continuous Glucose Monitoring at 24–28 Weeks’ Gestation. Diabetes 2026, 75 DOI: 10.2337/db26-1235-or.Peer-Reviewed Original ResearchConceptsGestational diabetes mellitusWeeks gestationNegative predictive valuePositive predictive valueContinuous glucose monitoring metricsContinuous glucose monitoringInfant hospitalizationGestational diabetes mellitus diagnostic criteriaDetection of gestational diabetes mellitusGestational diabetes mellitus diagnosisPredictive valueInfants Hospital of Rhode IslandCarpenter-Coustan criteriaContinuous glucose monitoring dataGestational diabetes diagnosisMeasures of glycemic variabilityAmerican Diabetes AssociationNational InstituteDigestive and Kidney DiseasesCarpenter-CoustanPregestational diabetesMassachusetts General HospitalContinuous glucose monitoring systemGlycemic thresholdsGlucose monitoring1073-OR: Associations of Early Pregnancy Maternal Glycemic and Metabolic Measures with Newborn Adiposity
VESCO K, FACCO F, FEGHALI M, GROBMAN W, KILLEEN A, LEBLANC E, LOWE W, MERRIAM A, MOURAD M, OSHIRO C, POWE C, REDDY U, ROUSE D, SCHOLTENS D, SHERR J, SPADOLA A, WERNER E, YEE L, ZORK N, LANCKI N, CATALANO P. 1073-OR: Associations of Early Pregnancy Maternal Glycemic and Metabolic Measures with Newborn Adiposity. Diabetes 2026, 75 DOI: 10.2337/db26-1073-or.Peer-Reviewed Original ResearchConceptsNewborn adiposityMaternal BMIFat massNational InstituteWeeks gestationRegression modelsPercent body fatInsulin sensitivityAmerican Diabetes AssociationInfant hospitalizationAssociated with FMInfants Hospital of Rhode IslandPre-existing diabetesEstimates of fat massNational Institutes of HealthAdiposity measuresDigestive and Kidney DiseasesInstitutes of HealthKaiser PermanenteMetabolic measuresMoms studyLinear regression modelsAssociated with higher measuresSecondary analysisDiabetes AssociationSevere Maternal Morbidity and Breastfeeding Among Nulliparous Individuals in the United States.
Bank T, Wu J, Catov J, Yee L, Haas D, McNeil R, Ranzini A, Simhan H, Reddy U, Hoffman M, Silver R, Levine L, Saade G, Chung J, Lynch C, Grobman W, Venkatesh K. Severe Maternal Morbidity and Breastfeeding Among Nulliparous Individuals in the United States. Obstetrics And Gynecology 2026 PMID: 42241707, DOI: 10.1097/aog.0000000000006345.Peer-Reviewed Original ResearchConceptsSevere maternal morbidityMaternal morbidityNulliparous individualsProspective cohortNontransfusion severe maternal morbidityBreastfeeding initiationAssociated with breastfeeding initiationWeeks to 6 monthsDuration of breastfeedingBreastfeeding durationPregnant individualsBreastfeedingUnited StatesSecondary analysisMorbidityMonthsWeeksDurationNontransfusedDeliveryIndividualsNeonatal Inflammatory Profiles Associated With Perinatally Acquired Hepatitis C Viral Infection
Fisher S, Sandoval G, Saade G, Hughes B, Reddy U, Chien E, Tita A, Thorp J, Metz T, Sabharwal V, Simhan H, Swamy G, Heyborne K, Sibai B, Yee L, El-Sayed Y, Casey B, Parry S, Prasad M. Neonatal Inflammatory Profiles Associated With Perinatally Acquired Hepatitis C Viral Infection. The Pediatric Infectious Disease Journal 2026, 10.1097/inf.0000000000005262. PMID: 42083082, PMCID: PMC13245272, DOI: 10.1097/inf.0000000000005262.Peer-Reviewed Original ResearchConceptsNested Case-Control StudyCase-control study of infantsMarkers of T-cell exhaustionDeath-ligand 1T cell exhaustionHepatitis C infectionHepatitis C exposureAged 2 monthsStudy of infantsPlasma cytokines/chemokinesPerinatal transmissionC infectionInfantsNegative controlC exposureDetect biomarkersCytokines/chemokinesPlasmaBiomarkersAssociation between a Periconception Healthy Plant-Based Diet and Adverse Pregnancy Outcomes
Jancsura M, Grobman W, Wu J, Griffis H, Wirth M, Haas D, Silver R, Feghali M, Reddy U, Levine L, Saade G, Yee L, Lindsay K, Venkatesh K. Association between a Periconception Healthy Plant-Based Diet and Adverse Pregnancy Outcomes. Journal Of Nutrition 2026, 156: 101577. PMID: 42082019, PMCID: PMC13279371, DOI: 10.1016/j.tjnut.2026.101577.Peer-Reviewed Original ResearchAltmetricMeSH Keywords and ConceptsConceptsHealthy plant-based diet indexAdverse pregnancy outcomesGestational diabetes mellitusAssociated with lower riskRisk of HDPHealthy plant-based dietPreterm birthNulliparous individualsGestational ageFood accessPregnancy outcomesDietary patternsAssociated with adverse pregnancy outcomesBlock Food Frequency QuestionnairePlant-based dietsAssociated with preterm birthNeighborhood food accessPlant-based dietary patternsPlant-based diet indexFood frequency questionnaireLow food accessHigher DASH scoresPoisson regression modelsHypertensive disordersCardiometabolic healthAtherosclerotic cardiovascular disease (ASCVD) biomarkers 5–10 years after a hypertensive disorder of pregnancy
Sinkey R, McGee P, Subramaniam A, Casey B, Reddy U, Rouse D, Tita A, Thorp J, Chien E, Saade G, Blackwell S, Landon M, Development F. Atherosclerotic cardiovascular disease (ASCVD) biomarkers 5–10 years after a hypertensive disorder of pregnancy. Pregnancy Hypertension 2026, 44: 101467. PMID: 42001672, PMCID: PMC13222657, DOI: 10.1016/j.preghy.2026.101467.Peer-Reviewed Original ResearchConceptsHypertensive disorders of pregnancyAtherosclerotic cardiovascular diseaseDisorders of pregnancyHypertensive disordersHs-CRPSerum creatinineNormotensive controlsCardiovascular diseaseHigh-sensitivity C-reactive proteinAssociated with future cardiovascular diseaseFuture cardiovascular diseaseC-reactive proteinTrials of treatmentYear of childbirthMild GDMGestational diabetesFollow-up studyApolipoprotein BAdjusted meansCreatininePatientsPregnancySecondary analysisApoBBiomarkers
Academic Achievements & Community Involvement
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Activities
activity New England Journal of Medicine
2025 - PresentJournal ServiceRevieweractivity JAMA
2025 - PresentJournal ServiceRevieweractivity Lancet
2025 - PresentJournal ServiceRevieweractivity Addictive Behaviors
2025 - PresentJournal ServiceRevieweractivity Advances in Public Health
2025 - PresentJournal ServiceReviewer
Honors
honor Invitation to The White House Stillbirth Prevention Event to celebrate the passing of the Maternal and Child Health Stillbirth Prevention Act,
01/01/2024Other AwardWashington, DChonor Elected Member
01/01/2024Other AwardNational Academy of Medicinehonor Elected Member
01/01/2024National AwardNational Academy of Medicinehonor Executive Leadership in Academic Medicine
01/01/2022, 01/01/2020Other Award(ELAM) Program for Womenhonor Yale Medicine Advanced Leaders Program, School of Management
01/01/2021, 01/01/2020Yale University AwardYale University
Clinical Care
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Overview
As an obstetrician-gynecologist who specializes in high-risk pregnancies, Uma Reddy, MD, MPH, says she enjoys taking care of mothers—and children—when they need it most.
“If you have an uncomplicated pregnancy, the baby is staring off life on the right foot. But if you have complications, that can set the child up for a lifetime of increased risks and chronic diseases,” explains Dr. Reddy, who is director of Maternal-Fetal Medicine. “For me, it’s exciting to be right there at the beginning and try to maximize a mother and baby’s health. And for high-risk pregnancies, where women have concerns, it’s rewarding to see a healthy birth.”
Dr. Reddy treats women whose pregnancies are considered complicated for a number of reasons, including a mother or child with a heart defect, a baby with a birth defect, or women who have previously experienced a stillbirth or a preterm birth.
“Ten percent of pregnancies in the United States are complicated by a preterm birth, which is when a baby is born before 37 weeks,” Dr. Reddy explains. “It’s a common complication and our goal is to prevent another preterm birth if a woman has already had one. We also treat a variety of maternal medical conditions, such as women who have diabetes, high blood pressure, or connective tissue disorders like lupus that might put them at higher risk of complication.”
Dr. Reddy’s research focuses on stillbirth, including examining causes and ways to better prevent it. She spent much of her career at the National Institutes of Health, where she led the Maternal Fetal Medicine Units Network, which funds multiple clinical trials across the country.
Dr. Reddy is also a professor of obstetrics, gynecology and reproductive sciences at Yale School of Medicine.
Clinical Specialties
Board Certifications
Maternal-Fetal Medicine
- Certification Organization
- AB of Obstetrics & Gynecology
- Original Certification Date
- 2003
Obstetrics & Gynecology
- Certification Organization
- AB of Obstetrics & Gynecology
- Original Certification Date
- 1997
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Contacts
Yale School of Medicine
PO Box 208063
New Haven , CT 06520-8063
United States