Thomas McGlashan, MD
Professor Emeritus of PsychiatryCards
About
Research
Publications
2024
Sex differences in clinical presentation in youth at high risk for psychosis who transition to psychosis
Chintoh A, Liu L, Braun A, Akseer S, Bearden C, Cadenhead K, Cornblatt B, Keshavan M, Mathalon D, McGlashan T, Perkins D, Seidman L, Stone W, Tsuang M, Walker E, Woods S, Cannon T, Addington J. Sex differences in clinical presentation in youth at high risk for psychosis who transition to psychosis. Schizophrenia Research 2024, 271: 153-160. PMID: 39029145, DOI: 10.1016/j.schres.2024.07.030.Peer-Reviewed Original ResearchClinical high riskClinical high-risk individualsSex differencesNegative symptomsTransition to psychosisInvestigate sex differencesNo sex differencesSchizophreniform disorderCHR individualsPsychosisSubstance useSchizophreniaSymptomsHigh riskIndividualsSchizophreniformAnxietyClinical presentationSexDepressionDisordersBaselineDifferencesMaleYouth
2023
Linking enlarged choroid plexus with plasma analyte and structural phenotypes in clinical high risk for psychosis: A multisite neuroimaging study
Bannai D, Reuter M, Hegde R, Hoang D, Adhan I, Gandu S, Pong S, Raymond N, Zeng V, Chung Y, He G, Sun D, van Erp T, Addington J, Bearden C, Cadenhead K, Cornblatt B, Mathalon D, McGlashan T, Jeffries C, Stone W, Tsuang M, Walker E, Woods S, Cannon T, Perkins D, Keshavan M, Lizano P. Linking enlarged choroid plexus with plasma analyte and structural phenotypes in clinical high risk for psychosis: A multisite neuroimaging study. Brain Behavior And Immunity 2023, 117: 70-79. PMID: 38169244, PMCID: PMC10932816, DOI: 10.1016/j.bbi.2023.12.021.Peer-Reviewed Original ResearchNorth American Prodrome Longitudinal Study 2Plasma analytesTotal white matter volumeChoroid plexus enlargementLarger lateral ventricle volumesLateral ventricle volumeWhite matter volumeClinical high riskSubcortical gray matterChronic psychosisNeuroanatomical alterationsBaseline scanPsychosis onsetHigh riskChoroid plexusMatter volumeVentricle volumeConversion statusGray matterNeuroimaging studiesPsychosisStructural phenotypesImportant biomarkerEnlargementLongitudinal Study 2
2009
Ten-Year Stability and Latent Structure of the DSM–IV Schizotypal, Borderline, Avoidant, and Obsessive-Compulsive Personality Disorders
Sanislow CA, Little TD, Ansell EB, Grilo CM, Daversa M, Markowitz JC, Pinto A, Shea MT, Yen S, Skodol AE, Morey LC, Gunderson JG, Zanarini MC, McGlashan TH. Ten-Year Stability and Latent Structure of the DSM–IV Schizotypal, Borderline, Avoidant, and Obsessive-Compulsive Personality Disorders. Journal Of Psychopathology And Clinical Science 2009, 118: 507-519. PMID: 19685948, PMCID: PMC6445274, DOI: 10.1037/a0016478.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultBorderline Personality DisorderCohort StudiesCompulsive Personality DisorderDepressive Disorder, MajorDiagnostic and Statistical Manual of Mental DisordersFemaleHumansLongitudinal StudiesMaleMiddle AgedModels, PsychologicalPersonality DisordersProspective StudiesPsychometricsReproducibility of ResultsSchizotypal Personality DisorderSex FactorsYoung AdultConceptsPersonality disorderTime pointsCross-sectional studyTen-year stabilityObsessive-compulsive personality disorderCollaborative Longitudinal Personality DisordersMental disordersObsessive-compulsive PDPD diagnosisStatistical ManualMean levelsDisordersAvoidant PDImpending revisionInitial time pointPrior factor analytic studiesSemistructured interviewsDiagnostic constructsSchizotypalAnalytic studyLongitudinal modelFactor analytic studiesDiagnosisPathologyValidity of the Prodromal Risk Syndrome for First Psychosis: Findings From the North American Prodrome Longitudinal Study
Woods SW, Addington J, Cadenhead KS, Cannon TD, Cornblatt BA, Heinssen R, Perkins DO, Seidman LJ, Tsuang MT, Walker EF, McGlashan TH. Validity of the Prodromal Risk Syndrome for First Psychosis: Findings From the North American Prodrome Longitudinal Study. Schizophrenia Bulletin 2009, 35: 894-908. PMID: 19386578, PMCID: PMC2728816, DOI: 10.1093/schbul/sbp027.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentComorbidityDisability EvaluationDisease ProgressionEarly DiagnosisFemaleHumansLongitudinal StudiesMalePatient Acceptance of Health CarePsychiatric Status Rating ScalesPsychometricsPsychotic DisordersReproducibility of ResultsRisk AssessmentSchizophreniaSchizophrenic PsychologySchizotypal Personality DisorderSocial AdjustmentUnited StatesYoung AdultConceptsProdromal risk syndromeNorth American Prodrome Longitudinal StudyRisk syndromeFirst psychosisProdromal SyndromesSchizotypal personality disorder groupDiagnostic validityLongitudinal studyFHR subjectsYounger patientsPersonality disorder groupSPD patientsPrevention StudyProdromal patientsPsychosis prodromeSyndrome patientsNC subjectsPatientsMeeting criteriaFuture psychosisSyndromeMental disordersPsychosisDisorder groupStatistical Manual
Academic Achievements & Community Involvement
News
News
- February 01, 2022
Mindmap Reduced Duration of Untreated Psychosis in the New Haven Area
- April 15, 2019
PRIME Clinic expands, offering pre-psychosis treatment for young people
- February 22, 2016
3 Yale Psychiatry faculty named to 'World's Most Influential Scientific Minds' report
- February 04, 2016
In memoriam: Dr. Ralph E. Hoffman, pioneer in study of auditory hallucinations
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Psychiatry
300 George St
New Haven, CT 06511-
United States