Praveen Suthaharan
Graduate School StudentAbout
Research
Publications
2026
649. Paranoia Differentiates Meso-Limbic Activations in Schizophrenia During Volatility-Related Belief Updating
Vassall S, Rogers B, Sloan A, Suthaharan P, Corlett P, Sheffield J. 649. Paranoia Differentiates Meso-Limbic Activations in Schizophrenia During Volatility-Related Belief Updating. Biological Psychiatry 2026, 99: s378. DOI: 10.1016/j.biopsych.2026.03.883.Peer-Reviewed Original ResearchAnhedonia and Anxious Arousal Are Associated With Distinct Expectations About the Statistics of a Volatile Environment
Duda J, Cannon T, Paskewitz S, Palmer W, Suthaharan P, Kenney J, Corlett P, Joormann J. Anhedonia and Anxious Arousal Are Associated With Distinct Expectations About the Statistics of a Volatile Environment. Biological Psychiatry Global Open Science 2026, 6: 100736. PMID: 42293406, PMCID: PMC13260089, DOI: 10.1016/j.bpsgos.2026.100736.Peer-Reviewed Original ResearchAnxious arousalAversive contextAnxiety symptomsProbabilistic reversal-learning taskProbability of negative eventsReversal-learning taskBayesian model of inferenceMarkers of depressionInitial expectationsAdjustment of behaviorCommunity sampleInternalizing disordersLoss contextNegative eventsExploratory behaviorAnhedoniaAnxietyDepressionElevated expectationsModel of inferenceCausal structureArousalHierarchical Bayesian modelVolatile environmentBeliefsSelf-Reflection Protects Behavior from Volatile Beliefs Linked to Paranoia
Suthaharan P, Castiello S, Ang Y, Corlett P. Self-Reflection Protects Behavior from Volatile Beliefs Linked to Paranoia. Computational Psychiatry 2026, 10: 18-34. PMID: 41727381, PMCID: PMC12922661, DOI: 10.5334/cpsy.150.Peer-Reviewed Original ResearchProbabilistic reversal learning taskMetacognitive structuringReversal learning taskGeneral cognitive abilityHigher paranoiaPsychiatric conditionsCognitive abilitiesLearning tasksParanoiaMetacognitionSelf-ReflectionBeliefsOpen-ended questionsMetacognitive promptsCognitionProtective behaviorsIndividualsBehaviorTaskDebriefing questionsPromptsVerboseHypothesisVolatility
2025
Pseudo-specificity, pseudo-modules, and pseudo-models in paranoia
Corlett P, Rossi-Goldthorpe R, Suthaharan P, Sheffield J, de Obeso S, Heyes C. Pseudo-specificity, pseudo-modules, and pseudo-models in paranoia. Trends In Cognitive Sciences 2025, 29: 1067-1068. PMID: 41015682, DOI: 10.1016/j.tics.2025.09.007.Commentaries, Editorials and LettersPseudosocial cognition and paranoia
Corlett P, Rossi-Goldthorpe R, Suthaharan P, Sheffield J, de Obeso S, Heyes C. Pseudosocial cognition and paranoia. Trends In Cognitive Sciences 2025, 29: 997-1006. PMID: 40518352, DOI: 10.1016/j.tics.2025.05.019.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2024
Lesions to the mediodorsal thalamus, but not orbitofrontal cortex, enhance volatility beliefs linked to paranoia
Suthaharan P, Thompson S, Rossi-Goldthorpe R, Rudebeck P, Walton M, Chakraborty S, Noonan M, Costa V, Murray E, Mathys C, Groman S, Mitchell A, Taylor J, Corlett P, Chang S. Lesions to the mediodorsal thalamus, but not orbitofrontal cortex, enhance volatility beliefs linked to paranoia. Cell Reports 2024, 43: 114355. PMID: 38870010, PMCID: PMC11231991, DOI: 10.1016/j.celrep.2024.114355.Peer-Reviewed Original ResearchOrbitofrontal cortexMediodorsal thalamusReward learning rateAssociated with paranoiaExcitotoxic lesionsBrain regionsUnoperated monkeysAction selectionAdaptive behaviorParanoiaBelief updatingMDmcMeaningful changeCortexThalamusBeliefsLearning rateRobust to variabilityCompare performanceRewardBehaviorBrainMonkeysAction policiesPerception
2023
Relationships between cognitive biases, decision-making, and delusions
Sheffield J, Smith R, Suthaharan P, Leptourgos P, Corlett P. Relationships between cognitive biases, decision-making, and delusions. Scientific Reports 2023, 13: 9485. PMID: 37301915, PMCID: PMC10257713, DOI: 10.1038/s41598-023-36526-1.Peer-Reviewed Original ResearchConceptsDelusional ideationDelusional thinkingCognitive biasesDistinct cognitive processesSelf-reported dataCognitive processesProbabilistic reversalUnique varianceComputational mechanismsEvidence integrationPsychosis spectrumMultiple measuresProportion of varianceParanoiaRandom explorationIdeationThinkingTaskBiasesMeasuresVarianceDelusionsJTCIndependent studiesRelationshipAssumed shared belief about conspiracy theories in social networks protects paranoid individuals against distress
Suthaharan P, Corlett P. Assumed shared belief about conspiracy theories in social networks protects paranoid individuals against distress. Scientific Reports 2023, 13: 6084. PMID: 37055504, PMCID: PMC10100615, DOI: 10.1038/s41598-023-33305-w.Peer-Reviewed Original ResearchConceptsConspiratorial beliefsConspiracy theoriesLess emotional distressIndividual-level processesParanoid individualsClinical paranoiaParanoid beliefsPsychological studiesConspiracy beliefsEmotional distressPersecutory delusionsBehavioral predictorsSocial supportBelief formationSocial accountsSocial networksOrganizational factorsParanoiaBroader social networksBeliefsLarge social networksSocietal normsDistressTaskLevel processes
2022
Belief Updating and Paranoia in Individuals With Schizophrenia
Sheffield JM, Suthaharan P, Leptourgos P, Corlett PR. Belief Updating and Paranoia in Individuals With Schizophrenia. Biological Psychiatry Cognitive Neuroscience And Neuroimaging 2022, 7: 1149-1157. PMID: 35430406, PMCID: PMC9827723, DOI: 10.1016/j.bpsc.2022.03.013.Peer-Reviewed Original ResearchConceptsBelief updatingThought contentPersecutory delusionsUnusual thought contentHierarchical Gaussian FilterMeasures of anxietyPrior beliefsSignificant indirect effectHealthy control participantsCognitive mechanismsProbabilistic reversalPersecutory beliefsParanoia continuumWorry QuestionnaireNegative Syndrome ScaleControl participantsParanoiaModel implicatingIndirect effectsSymptom Rating ScaleSyndrome ScaleWorryBeliefsSchizophreniaSignificant worryRelating Glutamate, Conditioned, and Clinical Hallucinations via 1H-MR Spectroscopy
Leptourgos P, Bansal S, Dutterer J, Culbreth A, Powers A, Suthaharan P, Kenney J, Erickson M, Waltz J, Wijtenburg SA, Gaston F, Rowland LM, Gold J, Corlett P. Relating Glutamate, Conditioned, and Clinical Hallucinations via 1H-MR Spectroscopy. Schizophrenia Bulletin 2022, 48: 912-920. PMID: 35199836, PMCID: PMC9212089, DOI: 10.1093/schbul/sbac006.Peer-Reviewed Original ResearchConceptsGlutamate levelsAnterior insulaPrior beliefsCognitive modelPathophysiological theoriesAuditory cortexClinical hallucinationsAnterior cingulateComputational psychiatryNew treatmentsDorsolateral prefrontalVisual cuesPrior expectationsSame participantsHallucinationsInsulaNegative relationshipCurrent experienceMagnetic resonance spectroscopyBeliefsComputational modelingTone