Justin Belcher, MD, PhD, FASN
Associate Professor of Medicine (Nephrology)Cards
About
Research
Publications
2024
Acute Kidney Injury in Patients with Cirrhosis and Chronic Kidney Disease: Results from the HRS-HARMONY Consortium
St. Hillien S, Robinson J, Ouyang T, Patidar K, Belcher J, Cullaro G, Regner K, Chung R, Ufere N, Velez J, Neyra J, Asrani S, Wadei H, Teixeira J, Saly D, Levitsky J, Orman E, Sawinski D, Dageforde L, Allegretti A, Consortium H. Acute Kidney Injury in Patients with Cirrhosis and Chronic Kidney Disease: Results from the HRS-HARMONY Consortium. Clinical Gastroenterology And Hepatology 2024 PMID: 39675402, DOI: 10.1016/j.cgh.2024.10.023.Peer-Reviewed Original ResearchAcute kidney injuryChronic kidney diseaseLiver function parametersKidney diseaseKidney injuryAssociated with lower 90-day mortalityRates of intensive care unit admissionLiver diseaseAlcohol-associated liver diseaseIntensive care unit admissionMELD-Na scoreRenal replacement therapyShort-term outcomesFunction parametersComparison of outcomesPeak creatinineAdmission creatinineTransplant listing statusReplacement therapyUnit admissionPrimary outcomeCirrhosisMetabolic dysfunctionHospitalized patientsPatientsHepatorenal Syndrome-AKI Reversal and Liver Transplant Rates in Patients Treated with Terlipressin
Belcher J, Regner K, Subramanian R, Mujtaba M, Allegretti A, Cardoza S, Wadei H. Hepatorenal Syndrome-AKI Reversal and Liver Transplant Rates in Patients Treated with Terlipressin. Journal Of The American Society Of Nephrology 2024, 35: 10.1681/asn.2024934zvv6h. DOI: 10.1681/asn.2024934zvv6h.Peer-Reviewed Original ResearchAssociation of Hepatorenal Syndrome-Acute Kidney Injury with Mortality in Patients with Cirrhosis Requiring Renal Replacement Therapy
Cama-Olivares A, Ouyang T, Takeuchi T, St. Hillien S, Robinson J, Chung R, Cullaro G, Karvellas C, Levitsky J, Orman E, Patidar K, Regner K, Saly D, Sawinski D, Sharma P, Teixeira J, Ufere N, Velez J, Wadei H, Wahid N, Allegretti A, Neyra J, Belcher J, Cama-Olivares A, Ouyang T, Takeuchi T, St. Hillien S, Robinson J, Chung R, Cullaro G, Karvellas C, Levitsky J, Orman E, Patidar K, Regner K, Saly D, Sawinski D, Sharma P, Teixeira J, Ufere N, Velez J, Wadei H, Wahid N, Allegretti A, Neyra J, Belcher J. Association of Hepatorenal Syndrome-Acute Kidney Injury with Mortality in Patients with Cirrhosis Requiring Renal Replacement Therapy. Kidney360 2024, 6: 247-256. PMID: 39348201, PMCID: PMC11882256, DOI: 10.34067/kid.0000000589.Peer-Reviewed Original ResearchEtiology of AKIHRS-AKIAKI-RRTRenal replacement therapyContinuous RRTIntermittent hemodialysisAdult patientsHospitalized patientsAKI etiologyReplacement therapyAssociated with increased 90-day mortalityMulticenter retrospective cohort studyNon-HRS-AKIAssociated with increased mortalityConsecutive adult patientsRetrospective cohort studyHospital network systemHepatorenal syndromeContemporary cohortInpatient populationMechanical ventilationRRT modalityCohort studyClinical variablesPrimary outcomeImpact of acute kidney injury response on survival and liver transplant rates in hospitalized patients with cirrhosis awaiting liver transplantation: Results from the HRS-HARMONY consortium
Li X, Ouyang T, Belcher J, Patidar K, Cullaro G, Asrani S, Wadei H, Simonetto D, Regner K, Dageforde L, Przybyszewski E, Wilechansky R, Sharma P, Ufere N, Duarte-Rojo A, Wahid N, Orman E, St. Hillien S, Robinson J, Chung R, Allegretti A, collaborative I. Impact of acute kidney injury response on survival and liver transplant rates in hospitalized patients with cirrhosis awaiting liver transplantation: Results from the HRS-HARMONY consortium. Liver Transplantation 2024, 30: 1106-1115. PMID: 39073567, DOI: 10.1097/lvt.0000000000000445.Peer-Reviewed Original ResearchAKI responseAcute kidney injuryTransplant-free survivalLiver transplantationLT ratesCirrhosis patientsNon-respondersTime of liver transplantationCourse of hospitalized patientsNo responseRetrospective multicenter studyMELD-Na scoreResponse to therapyResponse to treatmentLiver transplant ratesRate of LTOverall survivalMulticenter studyKidney injuryCirrhosis etiologyCirrhosisHospitalized patientsTransplantationPatientsInjury responseOutcomes of patients with alcohol‐associated hepatitis and acute kidney injury – Results from the HRS Harmony Consortium
T. A, Allegretti A, Cullaro G, Ouyang T, Asrani S, Chung R, Przybyszewski E, Wilechansky R, Robinson J, Sharma P, Simonetto D, Jalal P, Orman E, Wadei H, St. Hillien S, Saly D, Ufere N, Dageforde L, Regner K, Belcher J, Patidar K, Consortium F. Outcomes of patients with alcohol‐associated hepatitis and acute kidney injury – Results from the HRS Harmony Consortium. Alimentary Pharmacology & Therapeutics 2024, 60: 778-786. PMID: 39010302, PMCID: PMC11349455, DOI: 10.1111/apt.18159.Peer-Reviewed Original ResearchAlcohol-associated hepatitisAcute kidney injuryAcute kidney injury phenotypesHepatorenal syndromeMELD-NaDevelopment of acute kidney injuryCumulative incidence of deathConsecutive adult patientsOutcomes of patientsAlcohol Abuse and Alcoholism (NIAAANon-AH groupRenal replacement therapyPresence of AHAcute tubular necrosisRetrospective cohort studyPredictors of mortalityIncidence of deathAKI stageClinical courseReplacement therapyAdult patientsKidney injuryCumulative incidencePoor prognosisTubular necrosisUse of Terlipressin in AKI Associated with Hepatorenal Syndrome: PRO
Belcher J. Use of Terlipressin in AKI Associated with Hepatorenal Syndrome: PRO. Kidney360 2024, 5: 791-794. PMID: 38526157, PMCID: PMC11219105, DOI: 10.34067/kid.0000000000000341.Peer-Reviewed Original ResearchAcute kidney injury in patients with cirrhosis: Acute Disease Quality Initiative (ADQI) and International Club of Ascites (ICA) joint multidisciplinary consensus meeting
Nadim M, Kellum J, Forni L, Francoz C, Asrani S, Ostermann M, Allegretti A, Neyra J, Olson J, Piano S, VanWagner L, Verna E, Akcan-Arikan A, Angeli P, Belcher J, Biggins S, Deep A, Garcia-Tsao G, Genyk Y, Gines P, Kamath P, Kane-Gill S, Kaushik M, Lumlertgul N, Macedo E, Maiwall R, Marciano S, Pichler R, Ronco C, Tandon P, Velez J, Mehta R, Durand F. Acute kidney injury in patients with cirrhosis: Acute Disease Quality Initiative (ADQI) and International Club of Ascites (ICA) joint multidisciplinary consensus meeting. Journal Of Hepatology 2024, 81: 163-183. PMID: 38527522, PMCID: PMC11193657, DOI: 10.1016/j.jhep.2024.03.031.Peer-Reviewed Original ResearchAcute Disease Quality InitiativeInternational Club of AscitesAcute kidney injuryHRS-AKIQuality InitiativeHepatorenal syndromePost-discharge follow-upKidney injuryMultidisciplinary consensus meetingRisk of progression to chronic kidney diseaseProgression to chronic kidney diseasePhenotypes of acute kidney injuryFollow-up of patientsBridge to liver transplantationIncreased in-hospital morbidityIn-hospital morbidityPost-discharge follow-up of patientsChronic kidney diseaseMortality riskConsensus meetingInternational ClubCurative optionSplanchnic vasoconstrictorsAdvanced cirrhosisLiver transplantationHepatorenal Syndrome Type 1: Diagnosis and Treatment
Belcher J. Hepatorenal Syndrome Type 1: Diagnosis and Treatment. Advances In Kidney Disease And Health 2024, 31: 100-110. PMID: 38649214, DOI: 10.1053/j.akdh.2023.05.001.Peer-Reviewed Original ResearchConceptsAcute kidney injuryHepatorenal syndromeKidney injuryFunctional acute kidney injuryUrinary biomarkers of kidney injuryAssociated with significant morbidityFractional excretion of sodiumNeutrophil gelatinase-associated lipocalinDiagnostic criteriaBiomarkers of kidney injuryMultiple urinary biomarkersOptimal dosing strategiesExcretion of sodiumPoint-of-care ultrasoundAccurate differential diagnosisAnalog of vasopressinSets of diagnostic criteriaAdvanced cirrhosisAlbumin administrationSignificant morbidityVolume resuscitationTherapeutic optionsDosing strategiesFractional excretionDifferential diagnosis
2023
Outcomes of AKI on CKD in Hospitalized Cirrhotic Patients: Data from the HRS-HARMONY Consortium
St. Hillien S, Belcher J, Ouyang T, Robinson J, Regner K, Velez J, Patidar K, Cullaro G, Chung R, Allegretti A. Outcomes of AKI on CKD in Hospitalized Cirrhotic Patients: Data from the HRS-HARMONY Consortium. Journal Of The American Society Of Nephrology 2023, 34: 104-104. DOI: 10.1681/asn.20233411s1104b.Peer-Reviewed Original ResearchAssociation of AKI-Hepatorenal Syndrome (HRS) with Mortality in Hospitalized Cirrhotic Patients Requiring Renal Replacement Therapy: Results from the HRS-HARMONY Consortium
Cama-Olivares A, Ouyang T, Takeuchi T, St. Hillien S, Robinson J, Patidar K, Cullaro G, Chung R, Regner K, Velez J, Wahid N, Sharma P, Allegretti A, Neyra J, Belcher J. Association of AKI-Hepatorenal Syndrome (HRS) with Mortality in Hospitalized Cirrhotic Patients Requiring Renal Replacement Therapy: Results from the HRS-HARMONY Consortium. Journal Of The American Society Of Nephrology 2023, 34: 103-104. DOI: 10.1681/asn.20233411s1103c.Peer-Reviewed Original Research
Academic Achievements & Community Involvement
Clinical Care
Overview
Justin Belcher, MD, PhD, is a nephrologist who cares for people with a range of kidney-related conditions, including sudden loss of kidney function (due to acute kidney injury), chronic kidney disease (which develops over time), and disorders affecting the balance of acids, bases, and electrolytes. He also manages complex cases that require close monitoring in critical care settings.
As an associate professor of medicine (nephrology) at Yale School of Medicine, Dr. Belcher studies how new biological indicators can improve the diagnosis and treatment of kidney injury in people with cirrhosis. He is also dedicated to teaching and mentoring students, residents, and fellows.
Dr. Belcher received his medical training at Drexel University College of Medicine. He completed his residency, chief residency, and fellowship in nephrology, and earned a doctoral degree from Yale School of Medicine.