Jing Yan, PhD
Assistant Professor, Molecular, Cellular and Developmental BiologyCards
About
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Featured Publications
Bacteria surfing the elastic wave
Nijjer J, Cohen T, Yan J. Bacteria surfing the elastic wave. Nature Physics 2022, 19: 6-7. DOI: 10.1038/s41567-022-01862-y.Peer-Reviewed Original ResearchSocial evolution of shared biofilm matrix components
Tai J, Mukherjee S, Nero T, Olson R, Tithof J, Nadell C, Yan J. Social evolution of shared biofilm matrix components. Proceedings Of The National Academy Of Sciences Of The United States Of America 2022, 119: e2123469119. PMID: 35771939, PMCID: PMC9271185, DOI: 10.1073/pnas.2123469119.Peer-Reviewed Original ResearchMechanical Resilience of Biofilms toward Environmental Perturbations Mediated by Extracellular Matrix
Zhang Q, Nguyen D, Tai J, Xu X, Nijjer J, Huang X, Li Y, Yan J. Mechanical Resilience of Biofilms toward Environmental Perturbations Mediated by Extracellular Matrix. Advanced Functional Materials 2022, 32 DOI: 10.1002/adfm.202110699.Peer-Reviewed Original ResearchMechanical forces drive a reorientation cascade leading to biofilm self-patterning
Nijjer J, Li C, Zhang Q, Lu H, Zhang S, Yan J. Mechanical forces drive a reorientation cascade leading to biofilm self-patterning. Nature Communications 2021, 12: 6632. PMID: 34789754, PMCID: PMC8599862, DOI: 10.1038/s41467-021-26869-6.Peer-Reviewed Original ResearchMorphogenesis and cell ordering in confined bacterial biofilms
Zhang Q, Li J, Nijjer J, Lu H, Kothari M, Alert R, Cohen T, Yan J. Morphogenesis and cell ordering in confined bacterial biofilms. Proceedings Of The National Academy Of Sciences Of The United States Of America 2021, 118: e2107107118. PMID: 34330824, PMCID: PMC8346881, DOI: 10.1073/pnas.2107107118.Peer-Reviewed Original Research
2026
Near-atomic in situ architecture and membrane-coupled dynamics of the Vibrio cholerae sheathed flagellum
Guo W, Yue J, Park J, Valverde-Mendez D, Botting J, Yu H, Sen A, Kumar R, Yan J, Yildiz F, Liu J. Near-atomic in situ architecture and membrane-coupled dynamics of the Vibrio cholerae sheathed flagellum. Nature Communications 2026, 17: 9199. PMID: 42660870, DOI: 10.1038/s41467-026-75593-6.Peer-Reviewed Original ResearchCrystal structure of Vibrio cholerae polysaccharide lyase RbmB bound to Vibrio polysaccharide (VPS) fragments provides insights into substrate recognition and cleavage
Weerasekera R, Moreau A, Huang X, Potapova A, Schwechheimer C, Kandel R, Huynh Y, Cannizzo O, Gordon R, Gerace E, Hinbest A, Yang Y, Jiang X, Woods R, Yan J, Yildiz F, Olson R. Crystal structure of Vibrio cholerae polysaccharide lyase RbmB bound to Vibrio polysaccharide (VPS) fragments provides insights into substrate recognition and cleavage. Proceedings Of The National Academy Of Sciences Of The United States Of America 2026, 123: e2534280123. PMID: 41805565, PMCID: PMC12993940, DOI: 10.1073/pnas.2534280123.Peer-Reviewed Original ResearchConformations and sequence determinants in the lipid binding of an adhesive peptide derived from Vibrio cholerae biofilms
Huang X, Prasad R, Saluja S, Yang Y, Yan Q, Shuster S, Karatekin E, Olson R, Lin C, Davis C, Jiang X, Zhou H, Yan J. Conformations and sequence determinants in the lipid binding of an adhesive peptide derived from Vibrio cholerae biofilms. PLOS Pathogens 2026, 22: e1013990. PMID: 41712669, PMCID: PMC12965690, DOI: 10.1371/journal.ppat.1013990.Peer-Reviewed Original ResearchThis study investigates how a peptide from Vibrio cholerae biofilms binds lipid membranes via a conserved β-hairpin structure, providing insights into bacterial adhesion and potential biomedical applications.
2025
Vibrio cholerae adhesin-derived peptides mediate strong pull-off forces in aqueous media with high ionic strength
Ahmed S, Zhai S, Huang X, Sulaja S, Adewole A, Ioffe A, Merg A, Yan J, Andresen Eguiluz R. Vibrio cholerae adhesin-derived peptides mediate strong pull-off forces in aqueous media with high ionic strength. Colloids And Surfaces B Biointerfaces 2025, 260: 115390. PMID: 41478156, DOI: 10.1016/j.colsurfb.2025.115390.Peer-Reviewed Original ResearchStructures of the sheathed flagellum reveal mechanisms of assembly and rotation in Vibrio cholerae
Guo W, Zhang S, Park J, Stanton V, Asp M, Herrera H, Tai J, Yue J, Wang J, Guo J, Kumar R, Botting J, Wu S, Yan J, Klose K, Yildiz F, Liu J. Structures of the sheathed flagellum reveal mechanisms of assembly and rotation in Vibrio cholerae. Nature Microbiology 2025, 10: 3305-3314. PMID: 41174224, PMCID: PMC13137154, DOI: 10.1038/s41564-025-02161-x.Peer-Reviewed Original Research
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- Reconstructed 3D image of a Vibrio cholerae biofilm cluster. Color corresponds to height.
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Yale University
C144 Yale Science Building, 260 Whitney Ave.
New Haven, CT 06511
United States