E. Jennifer Edelman, MD, MHS, BS
Professor of Medicine (General Medicine)Cards
About
Research
Publications
2026
Clinicians’ Perspectives on Implementing Contingency Management to Promote Parental Smoking Cessation in Routine Infant Care
Flom J, Camenga D, Shabanova V, McCollum S, Sandoval J, Chairuengjitjaras P, Forray A, Ledgerwood D, Edelman E, Sharifi M. Clinicians’ Perspectives on Implementing Contingency Management to Promote Parental Smoking Cessation in Routine Infant Care. Academic Pediatrics 2026, 103301. PMID: 41871754, DOI: 10.1016/j.acap.2026.103301.Peer-Reviewed Original ResearchFramework analysisSmoking cessationEvidence-based smoking cessation interventionsPediatric cliniciansImplementation strategiesCaregiver behavior changePediatric primary careQualified health centersAnalysis of interview transcriptsParental smoking cessationAwareness of CMSecondhand smoke exposureSmoking cessation interventionsPersonal smoking historyViews of caregiversContingency managementRoutine infant carePositive viewPrimary careSupport caregiversThematic saturationCessation interventionsClinicians' attitudesImplementation researchClinician perspectivesEmergency Department–Initiated Buprenorphine for Opioid Use Disorder
D’Onofrio G, Herring A, Hawk K, Perrone J, Cowan E, McCormack R, Dziura J, Matthews A, Pantalon M, Owens P, Martel S, Coupet E, Lofwall M, Walsh S, Edelman E, Carpenter J, Strout T, Baumann M, Anderson E, Barrett T, Dorey A, Taillac P, Cochran G, Crandall C, Wilson J, Manteuffel J, Cole J, Whiteside L, Jones C, Samuels E, Huntley K, Fiellin D, Schwarz E, Williamson B, Lee J, Lanter P, Pope J, King A, Stolbach A, Jennings L, Chang B, Kim H, Ketcham E, Wightman R, D’Orazio J, Moore P, Lynch M, Sullivan R, O'Connor P. Emergency Department–Initiated Buprenorphine for Opioid Use Disorder. JAMA: The Journal Of The American Medical Association 2026, 335: 948-960. PMID: 41670966, PMCID: PMC12895321, DOI: 10.1001/jama.2025.27019.Peer-Reviewed Original ResearchMeSH KeywordsAdministration, SublingualAdultBuprenorphineDelayed-Action PreparationsEmergency Room VisitsFemaleFentanylHumansInjections, SubcutaneousMaleMiddle AgedNarcotic AntagonistsOpiate OverdoseOpiate Substitution TreatmentOpioid-Related DisordersPatient SatisfactionSelf AdministrationSubstance Withdrawal SyndromeConceptsClinical Opiate Withdrawal ScaleClinical Opiate Withdrawal Scale scoreExtended-release buprenorphineOpioid use disorderUse disorderIllicit opioid useSublingual buprenorphineDays of illicit opioid useOpioid use disorder treatmentCraving scoresTreatment engagementDisorder treatmentExtended-releaseOpiate Withdrawal ScaleLevels of withdrawalEmergency departmentInjectable buprenorphineUntreated opioid use disorderOpioid useSelf-AdministrationPrecipitated withdrawalWithdrawal ScaleEmergency department-initiated buprenorphineDay 7Multicenter Randomized Clinical TrialFood insecurity and COVID-19-related experiences among people with HIV: A mixed methods analysis and conceptual framework
Harsono D, Sklar K, Silver M, Frederick M, Villanueva M, Edelman E, Yager J. Food insecurity and COVID-19-related experiences among people with HIV: A mixed methods analysis and conceptual framework. PLOS ONE 2026, 21: e0342667. PMID: 41678510, PMCID: PMC12900320, DOI: 10.1371/journal.pone.0342667.Peer-Reviewed Original ResearchConceptsExperiences of food insecurityFood insecurity experiencesFood insecurityFree-text survey responsesHIV care engagementPoor health outcomesLikelihood of chronic diseaseHIV care settingsFocus group transcriptsEvidence-based interventionsLevels of food insecurityCOVID-19-related experiencesCOVID-19 pandemicSocial-ecological frameworkEthnic minority groupsCare engagementHealth disparitiesReceive careCare settingsGroup transcriptsHealth outcomesClinical staffSociodemographic factorsHIV clinicFocus groupsClinical Pharmacists, Medications, and Contingency Management for Targeting Smoking in HIV Clinics
Edelman E, Deng Y, Dziura J, Nahum-Shani I, Weiss J, Aoun-Barakat L, Bold K, Harsono D, Mistler C, Payne E, Aiudi S, Sigel K, Yager J, Ledgerwood D, Bernstein S. Clinical Pharmacists, Medications, and Contingency Management for Targeting Smoking in HIV Clinics. JAMA Network Open 2026, 9: e2560593. PMID: 41758512, PMCID: PMC12949440, DOI: 10.1001/jamanetworkopen.2025.60593.Peer-Reviewed Original ResearchConceptsNicotine replacement therapyTobacco use disorderRandomized clinical trialsClinical pharmacistsHIV clinicRandomized clinical trial of peopleSmoking cigarettesClinical pharmacist visitsTobacco-related outcomesNicotine replacement therapy groupContingency managementClinical trials of peopleIntention-to-treat principleTreatment strategiesTrials of peopleUse disorderPharmacist visitAdaptive treatment strategiesMain OutcomesWeeks of treatmentStage 1 treatmentSmoking reductionSecondary outcomesPrimary outcomeStage 1The association between long-term opioid therapy and composite infection-related dental outcomes
Black A, Gordon K, Dziura J, Barry D, Crystal S, Edelman E, Gibson G, Hamilton M, Jurasic M, Li Y, Marshall B, Skanderson M, Suda K, Becker W. The association between long-term opioid therapy and composite infection-related dental outcomes. PLOS ONE 2026, 21: e0341361. PMID: 41628103, PMCID: PMC12863492, DOI: 10.1371/journal.pone.0341361.Peer-Reviewed Original ResearchConceptsFood and Drug AdministrationDental coverageDental outcomesLong-term opioid therapyComprehensive dental coveragePartial opioid agonistFollow-up timeCox regression modelsOpioid use disorderAssociated with riskNational cohort studyPatient-provider discussionsOpioid therapyOpioid agonistsOpioid analgesicsChronic painDental diseaseMultivariate regression modelCohort studyDrug AdministrationPatientsUse disorderRegression modelsUnclear generalizabilityResidual confoundingInvestigator- and Site-Level Outcomes of Participation in an ED-Based Clinical Trial
Carpenter J, Hawk K, Herring A, Cowan E, McCormack R, Owens P, Martel S, Edelman E, Huntley K, Perrone J, D’Onofrio G, Schwarz E, Williamson B, Lee J, Jones C, Lanter P, Pope J, King A, Carpenter J, Whiteside L, Duber H, Miner J, Cole J, Manteuffel J, Miller J, Herring A, Stolbach A, Baumann M, Strout T, Jennings L, Chang B, Kim H, Perrone J, Jang D, Ketcham E, Samuels E, Wightman R, Anderson E, Wilson J, D’Orazio J, Moore P, Crandall C, Cotton J, Lynch M, Cochran G, Madsen T, Taillac P, Dorey A, Sullivan R, Barrett T, Wilson A, Hawk K. Investigator- and Site-Level Outcomes of Participation in an ED-Based Clinical Trial. JAMA Network Open 2026, 9: e2555847. PMID: 41661598, PMCID: PMC12887738, DOI: 10.1001/jamanetworkopen.2025.55847.Peer-Reviewed Original ResearchPenicillin Allergy Labels are Associated with Carbapenem/Monobactam Antibiotic Utilization among Patients Undergoing Hematopoietic Stem Cell Transplants
Belmont A, Reynolds J, Stone C, Valente M, Dziura J, Gehan D, Malinis M, Phillips E, Sarpong D, Seropian S, Edelman E. Penicillin Allergy Labels are Associated with Carbapenem/Monobactam Antibiotic Utilization among Patients Undergoing Hematopoietic Stem Cell Transplants. The Journal Of Allergy And Clinical Immunology 2026, 157: ab108. DOI: 10.1016/j.jaci.2025.12.320.Peer-Reviewed Original Research
2025
Implementation facilitation improves readiness for emergency department-initiated buprenorphine to treat opioid use disorder
Strout T, Dziura J, Barrett T, Cowan E, Hawk K, Herring A, Manteuffel J, Martel S, Owens P, McCormack R, Perrone J, Fiellin D, D'Onofrio G, Edelman E. Implementation facilitation improves readiness for emergency department-initiated buprenorphine to treat opioid use disorder. Journal Of Substance Use And Addiction Treatment 2025, 209845. PMID: 41354305, PMCID: PMC12826104, DOI: 10.1016/j.josat.2025.209845.Peer-Reviewed Original ResearchImplementation facilitatorsEmergency department-initiated buprenorphineOpioid use disorderED readinessRandomized clinical trialsMedical directorsED medical directorsSite principal investigatorsUse disorderTreatment of opioid use disorderNursing supportAddress barriersLikert scale ratingsPost-enrollmentLinear regression modelsPre-enrollmentInsurance coverageTreatment availabilityClinical trialsRegression modelsFacilitationBuprenorphineReadinessTime pointsScale ratingsAlcohol-Related Hospitalizations From 2016 to 2022
Bernstein E, Wilson L, Kruse G, Edelman E, Herzig S, Anderson T. Alcohol-Related Hospitalizations From 2016 to 2022. JAMA Network Open 2025, 8: e2550589. PMID: 41632143, PMCID: PMC12728657, DOI: 10.1001/jamanetworkopen.2025.50589.Peer-Reviewed Original ResearchAlcohol-related hospitalizationsCross-sectional studyDischarge diagnosis codesAlcohol use disorderLength of stayIn-Hospital MortalityDiagnosis codesPopulation-level alcohol consumptionAlcohol useUnhealthy alcohol useAlcohol-related diagnosesHealth care costsHealth care spendingMedical complicationsNational Inpatient SampleAnnual rateMain OutcomesCare costsCost of hospitalizationCare spendingAdministrative dataPrevention effortsAlcohol consumptionAlcohol use disorder treatmentUS trendsPsychosocial correlates of awareness of HIV pre-exposure prophylaxis (PrEP) among persons who inject drugs in Northeast Georgia
Haider M, Clinton S, Zaman J, Ahmed F, Mehra R, Arayasirikul S, McFarland W, Mirzazadeh A, Edelman E, Hansen N. Psychosocial correlates of awareness of HIV pre-exposure prophylaxis (PrEP) among persons who inject drugs in Northeast Georgia. AIDS Care 2025, ahead-of-print: 1-14. PMID: 41318110, DOI: 10.1080/09540121.2025.2592886.Peer-Reviewed Original ResearchSyringe service programsHIV pre-exposure prophylaxisPrEP awarenessPre-exposure prophylaxisPsychosocial correlatesAssociated with PrEP awarenessOdds of PrEP awarenessUptake of HIV pre-exposure prophylaxisHIV prevention continuumSexualized drug useInjected drugsHIV-negative PWIDPrEP informationHIV testingPrevention continuumHIV diagnosisHealth insurancePrEPPsychological stressDrug usePWIDPsychosocialHIVService programsNortheast Georgia
Clinical Trials
Current Trials
Exemplar Hospital Initiation Trial to Enhance Treatment Engagement (EXHIT ENTRE)
IRB ID2000030586RolePrincipal InvestigatorPrimary Completion Date02/28/2023Recruiting ParticipantsGenderBothAge18+ years
Academic Achievements & Community Involvement
Clinical Care
Overview
E. Jennifer Edelman, MD, MHS, specializes in HIV and addiction medicine. She provides patient care for HIV/AIDS and its associated complications, such as HIV-associated myopathy, dementia, and neurocognitive disorder.
In addition to her clinical work in HIV care, Dr. Edelman’s research examines substance use disorder treatment in HIV clinics, emergency department-initiated buprenorphine programs, and alcohol reduction interventions for people with HIV.
A recipient of the New England Society of General Internal Medicine Award for Excellence in Clinical Investigation and the Society of General Internal Medicine Lawrence Linn Award, her research has been supported by grants from the National Institutes of Health, the National Institute on Alcohol Abuse and Alcoholism, and the National Cancer Institute.
Dr. Edelman is a professor of medicine at Yale School of Medicine.
Clinical Specialties
Fact Sheets
Human Immunodeficiency Virus (HIV)
Learn More on Yale MedicineOpioid Use Disorder
Learn More on Yale MedicineStimulant Use Disorder
Learn More on Yale MedicineAlcohol Use Disorder
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Board Certifications
Addiction Medicine (Internal Medicine)
- Certification Organization
- AB of Addiction Medicine
- Latest Certification Date
- 2024
- Original Certification Date
- 2014
HIV Specialist
- Certification Organization
- American Academy of HIV Medicine
- Latest Certification Date
- 2021
- Original Certification Date
- 2013
Yale Medicine News
News
News
- March 02, 2026
Integrating Tobacco Treatment in HIV Care
- February 11, 2026Source: Yale News
Seven-Day Injectable, Daily Tablet Buprenorphine Equally Effective for ED Patients with Opioid Use Disorder
- February 03, 2026
Why Antibiotic Allergy Labels Deserve a Second Look
- May 27, 2025
Research Project Studies High Doses of an Opioid Use Disorder Medication Among Veterans
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PO Box 208056
New Haven, CT 06520-8025
United States
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