Divyesh Joshi
Associate Research ScientistDownloadHi-Res Photo
About
Titles
Associate Research Scientist
Departments & Organizations
- Internal Medicine
- Schwartz Lab
Research
Research at a Glance
Yale Co-Authors
Frequent collaborators of Divyesh Joshi's published research.
Florian Schüder, PhD
Martin Schwartz, PhD
Publications
2021
Early events in endothelial flow sensing
Tanaka K, Joshi D, Timalsina S, Schwartz MA. Early events in endothelial flow sensing. Cytoskeleton 2021, 78: 217-231. PMID: 33543538, DOI: 10.1002/cm.21652.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsFluid shear stressLymphatic endothelial cellsEndothelial cellsCytoskeletal pathwaysVascular morphogenesisBiochemical signalsGene expressionEC phenotypeLymphatic fluid flowEarly eventsPhysiologyImmediate mechanismPrimary mechanismRecent advancesMorphogenesisMechanotransductionSignalingPhenotypePathwayMechanismExpressionFlow sensingCellsImportant questions
2019
Dynamic host–guest interaction enables autonomous single molecule blinking and super-resolution imaging
Sasmal R, Das Saha N, Schueder F, Joshi D, Sheeba V, Jungmann R, Agasti SS. Dynamic host–guest interaction enables autonomous single molecule blinking and super-resolution imaging. Chemical Communications 2019, 55: 14430-14433. PMID: 31737873, DOI: 10.1039/c9cc07153a.Peer-Reviewed Original ResearchCitationsAltmetricConceptsSynthetic host–guest complexesReversible noncovalent interactionsHost-guest complexesHost-guest interactionsDynamic host-guest interactionsSupramolecular recognitionGuest moleculesNoncovalent interactionsSuper-resolution imagingRecognition processNanoscopicMoleculesComplexesPaintInteractionOFF stateStochastic switchingRudhira/BCAS3 couples microtubules and intermediate filaments to promote cell migration for angiogenic remodeling
Joshi D, Inamdar M. Rudhira/BCAS3 couples microtubules and intermediate filaments to promote cell migration for angiogenic remodeling. Molecular Biology Of The Cell 2019, 30: 1437-1450. PMID: 30995157, PMCID: PMC6724693, DOI: 10.1091/mbc.e18-08-0484.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsCell migrationCytoskeleton organizationMT stabilityIntermediate filamentsEC migrationCytoskeletal protein essentialMT-IFVimentin intermediate filamentsFocal adhesionsEndothelial cell migrationMouse developmentProtein essentialRudhiraAssign functionCytoskeleton modulationDynamic remodelingBlood vessel formationAngiogenic sproutingSprouting angiogenesisAngiogenic remodelingMicrotubulesEssential roleVessel formationSequence 3Migration
2018
Reversible encapsulations and stimuli-responsive biological delivery from a dynamically assembled cucurbit[7]uril host and nanoparticle guest scaffold
Sinha S, Saha N, Sasmal R, Joshi D, Chandrasekhar S, Bosco M, Agasti S. Reversible encapsulations and stimuli-responsive biological delivery from a dynamically assembled cucurbit[7]uril host and nanoparticle guest scaffold. Journal Of Materials Chemistry B 2018, 6: 7329-7334. PMID: 32226626, PMCID: PMC7100906, DOI: 10.1039/c8tb01596a.Peer-Reviewed Original ResearchCitationsAltmetricConceptsGuest moleculesCompetitive guest moleculeSmall molecule activationDrug release rateDrug delivery scaffoldsTherapeutic moleculesSupramolecular scaffoldsTissue penetration depthNontoxic platformReversible encapsulationMolecule activationBiological deliveryPayload releaseSmall moleculesMoleculesDelivery scaffoldsExternal controllabilityRelease rateScaffoldsNew strategyBenzylammoniumCell culture studiesRecent advancesDosage controlGuestsSynthetic Host–Guest Assembly in Cells and Tissues: Fast, Stable, and Selective Bioorthogonal Imaging via Molecular Recognition
Sasmal R, Saha N, Pahwa M, Rao S, Joshi D, Inamdar M, Sheeba V, Agasti S. Synthetic Host–Guest Assembly in Cells and Tissues: Fast, Stable, and Selective Bioorthogonal Imaging via Molecular Recognition. Analytical Chemistry 2018, 90: 11305-11314. PMID: 30148612, PMCID: PMC6569623, DOI: 10.1021/acs.analchem.8b01851.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsBioorthogonal strategiesBioorthogonal imagingNoncovalent interactionsCovalent reactionSynthetic host-guest systemsHost-guest assemblyHost-guest interactionsHost-guest systemsNoncovalent approachMolecular recognitionLack of selectivityBioorthogonal labelingNoncovalent mechanismsBalanced reactivitySensitive detectionAssembly strategyLabeling agentNew analytical toolsLiving cellsAnalytical toolsReactionCellular environmentStabilitySelectivityFluorophoresRudhira/BCAS3 is essential for mouse development and cardiovascular patterning
Shetty R, Joshi D, Jain M, Vasudevan M, Paul J, Bhat G, Banerjee P, Abe T, Kiyonari H, VijayRaghavan K, Inamdar M. Rudhira/BCAS3 is essential for mouse development and cardiovascular patterning. Scientific Reports 2018, 8: 5632. PMID: 29618843, PMCID: PMC5884795, DOI: 10.1038/s41598-018-24014-w.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsMouse developmentGenome-wide transcriptome analysisFirst knockout mouseDirectional cell migrationExtracellular matrix organizationExtra-embryonic tissuesSpheroid sprouting assaysEmbryonic day 9.5Endothelial cellsCKO embryosCardiovascular patterningNull embryosTranscriptome analysisRudhiraVascular patterningCardiovascular developmentCytoskeletal proteinsMolecular processesMatrix organizationCell adhesionCell migrationDay 9.5Peptidase activityYolk sacEssential role