Abhiram Natu, PhD
Postdoctoral Associate in the Child Study CenterDownloadHi-Res Photo
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Postdoctoral Associate in the Child Study Center
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Child Study Center
Postdoctoral AssociatePrimary
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- Child Study Center
- Vaccarino Lab
Education & Training
- PhD
- Advanced Centre for Treatment Research Education in Cancer, Epigenetics and Chromatin Biology
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Research at a Glance
Yale Co-Authors
Frequent collaborators of Abhiram Natu's published research.
Publications Timeline
A big-picture view of Abhiram Natu's research output by year.
Alexandre Jourdon, PhD
Flora Vaccarino, MD
Soraya Scuderi, PhD
12Publications
Publications
Featured Publications
Mitochondrial dysfunction and chromatin changes with autophagy-mediated survival in doxorubicin resistant cancer cell lines.
Natu A, Pedgaonkar A, Gupta S. Mitochondrial dysfunction and chromatin changes with autophagy-mediated survival in doxorubicin resistant cancer cell lines. Biochem Biophys Res Commun 2023, 648: 1-10. PMID: 36724554, DOI: 10.1016/j.bbrc.2023.01.081.Peer-Reviewed Original ResearchHepatocellular carcinoma: Understanding molecular mechanisms for defining potential clinical modalities.
Natu A, Singh A, Gupta S. Hepatocellular carcinoma: Understanding molecular mechanisms for defining potential clinical modalities. World J Hepatol 2021, 13: 1568-1583. PMID: 34904030, DOI: 10.4254/wjh.v13.i11.1568.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsHistone acetylation: a key determinant of acquired cisplatin resistance in cancer.
Natu A, Verma T, Khade B, Thorat R, Gera P, Dhara S, Gupta S. Histone acetylation: a key determinant of acquired cisplatin resistance in cancer. Clin Epigenetics 2024, 16: 8. PMID: 38172984, DOI: 10.1186/s13148-023-01615-5.Peer-Reviewed Original ResearchIntegrative epigenome-transcriptome analysis unravels cancer-specific over-expressed genes potentially regulating immune microenvironment in clear cell renal cell carcinoma.
Gadewal N, Natu A, Sen S, Rauniyar S, Bastikar V, Gupta S. Integrative epigenome-transcriptome analysis unravels cancer-specific over-expressed genes potentially regulating immune microenvironment in clear cell renal cell carcinoma. Biochim Biophys Acta Gen Subj 2024, 1868: 130596. PMID: 38471632, DOI: 10.1016/j.bbagen.2024.130596.Peer-Reviewed Original Research
2025
Raman spectroscopy for detecting gastric and liver cancer cells that entered a tolerant persistence state to survive cisplatin chemotherapy.
Singh A, Gupta I, Saha P, Hole A, Anthony F, Natu A, Smoot DT, Ashktorab H, Chilakapati MK, Gupta S. Raman spectroscopy for detecting gastric and liver cancer cells that entered a tolerant persistence state to survive cisplatin chemotherapy. Biochem Biophys Res Commun 2025, 790: 152891. PMID: 41175647, DOI: 10.1016/j.bbrc.2025.152891.Peer-Reviewed Original ResearchThe synergistic action of HDAC inhibitor with cisplatin impedes survival and proliferation of drug-tolerant persister in gastric and liver cancer cells.
Singh A, Natu A, Anthony F, Muthu H, Khade B, Smoot DT, Ashktorab H, Gupta S. The synergistic action of HDAC inhibitor with cisplatin impedes survival and proliferation of drug-tolerant persister in gastric and liver cancer cells. Clin Epigenetics 2025, 17: 168. PMID: 41063308, DOI: 10.1186/s13148-025-01966-1.Peer-Reviewed Original ResearchIn silico screening of phytochemicals against chromatin modifier, SETD7 for remodeling of the immunosuppressive tumor microenvironment in renal cancer.
Gadewal N, Patidar D, Natu A, Gupta S, Bastikar V. In silico screening of phytochemicals against chromatin modifier, SETD7 for remodeling of the immunosuppressive tumor microenvironment in renal cancer. Mol Divers 2025, 29: 4359-4369. PMID: 39602041, DOI: 10.1007/s11030-024-11038-w.Peer-Reviewed Original ResearchEngineering human neuronal diversity: Morphogens and stem cell technologies for neurodevelopmental biology
Scuderi S, Khouri-Farah N, Rauthan R, Natu A, Wang H, Nelson A, Jourdon A, Vaccarino F. Engineering human neuronal diversity: Morphogens and stem cell technologies for neurodevelopmental biology. Stem Cell Reports 2025, 20: 102615. PMID: 40930068, PMCID: PMC12447334, DOI: 10.1016/j.stemcr.2025.102615.Peer-Reviewed Original ResearchAltmetricMeSH Keywords and ConceptsConceptsNeural tube patterningStem cell technologyTube patterningTranscription factor networksComplex assortmentFactor networksPluripotent stem cellsNeuronal cellsPatterns in vivoCell technologyProgenitor cellsEmbryonic tissuesNeurodevelopmental biologyBrain-on-chipNeuropsychiatric disordersHuman brain developmentStem cellsBrain developmentCellsBrain organoidsPatterning processMorphogenTranscriptionBrainStem
2023
An increase in polyadenylation of histone isoforms, Hist1h2ah and Hist2h3c2, is governed by 3'-UTR in de-differentiated and undifferentiated hepatocyte.
Verma T, Natu A, Khade B, Gera P, Gupta S. An increase in polyadenylation of histone isoforms, Hist1h2ah and Hist2h3c2, is governed by 3'-UTR in de-differentiated and undifferentiated hepatocyte. Exp Biol Med (Maywood) 2023, 248: 948-958. PMID: 37021545, DOI: 10.1177/15353702231160328.Peer-Reviewed Original Research
2021
RPS13, a potential universal reference gene for normalisation of gene expression in multiple human normal and cancer tissue samples.
Rashid M, Shah SG, Natu A, Verma T, Rauniyar S, Gera PB, Gupta S. RPS13, a potential universal reference gene for normalisation of gene expression in multiple human normal and cancer tissue samples. Mol Biol Rep 2021, 48: 7967-7974. PMID: 34657252, DOI: 10.1007/s11033-021-06828-6.Peer-Reviewed Original Research
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