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Vasilis Vasiliou, PhD

Department Chair and Susan Dwight Bliss Professor of Epidemiology (Environmental Health Sciences) and of Ophthalmology and Visual Science and of Environment
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Additional Titles

Director, Yale Superfund Research Center

Affiliated Faculty, Yale Cancer Center

Affiliated Faculty, Yale Institute for Global Health

Co-Director, Environmental Health Sciences Track, Executive MPH

About

Titles

Department Chair and Susan Dwight Bliss Professor of Epidemiology (Environmental Health Sciences) and of Ophthalmology and Visual Science and of Environment

Director, Yale Superfund Research Center; Affiliated Faculty, Yale Cancer Center; Affiliated Faculty, Yale Institute for Global Health; Co-Director, Environmental Health Sciences Track, Executive MPH

Biography

Vasilis Vasiliou, is Professor and Chair of the Department of Environmental Health Sciences. He received his BSc in Chemistry (1983) and PhD in Biochemical Pharmacology (1988) from the University of Ioannina, Greece. He then trained in gene-environment interactions, molecular toxicology and pharmacogenetics at the Department of Environmental Health in the College of Medicine at the University of Cincinnati (1991-1995). In 1996, he joined the faculty of the University of Colorado School of Pharmacy where he rose through the ranks to become Professor and Director of the Toxicology Graduate Program. Since 2008, he was also Professor of Ophthalmology at the University of Colorado School of Medicine. In July 2014, he joined the faculty of Yale University in his new position.

Professor Vasiliou has established an internationally-recognized research program that has been continuously funded by NEI/NIH and NIAAA/NIH since 1997, and recently NIEHS. His research interests include the etiology and molecular mechanisms of environmentally-induced human disease, such as liver disease, obesity & diabetes, cancer, and neurodegenerative diseases. His research focuses on the means by which the exposome (total exposures throughout life), metabolism (specifically aldehyde dehydrogenases and cytochrome P-450s) and antioxidants (glutathione and catalase) contribute to human health and disease. His laboratory utilizes state-of-the-art integrated system approaches that include metabolomics, lipidomics, exposomics, tissue imaging mass spectrometry, deep-learning, as well as human cohorts and genetically-engineered mouse models in order to elucidate mechanisms, and to discover biomarkers and novel interventions for human disease.

Dr Vasiliou is the director of the NIEHS-funded P42 Yale Superfund Research Center and also the director of the NIAAA-funded R24-Resource Center for Mouse Models and Metabolomics Tools to Investigate Alcohol Metabolism and Tissue Injury.

Dr. Vasiliou has published over 250 papers and edited three books on Alcohol and Cancer. Dr. Vasiliou is the editor of Human Genomics and serves on the editorial boards of several toxicology and visual sciences journals.

Professor Vasiliou is committed to training the next generation of scientists. At the University of Colorado, he was the Director of the Environmental and Molecular Toxicology Graduate Program for 15 years. At Yale he leads an NIAAA-funded T32 Translational Alcohol Research Program (TARP) Training Program for post-doctoral fellows, and an NIHES -funded R25 Summer Research Experience in Environmental Health (SREEH) Training Program that introduce undergraduate students in Connecticut (CT) to Environmental Health Research. Dr. Vasiliou has trained mentored and advised more than 60 trainees ranging from MPH and PhD students to postdoctoral fellows and junior faculties.

Appointments

Education & Training

PhD
University of Ioannina (1988)

Research

Overview

  • Alcohol and Colon Cancer
  • Alcohol and Drinking Behavior
  • Ocular Crystallins as Cellular Response to UV radiation
  • Glutathione in Eye Development
  • Glutathione in Obesity & Diabetes
  • Drug Discovery (Targeting Cancer Stem Cells)

Medical Research Interests

Alcoholism; Aldehyde Dehydrogenase; Diabetes Mellitus; Environmental Health; Genomics; Glutathione; Gout; Mass Spectrometry; Ophthalmology

Public Health Interests

Cancer; Environmental Health; Genetics, Genomics, Epigenetics; Global Health; Maternal & Child Health; Metabolism; Nutrition; Substance Use, Addiction; Metabolomics; COVID-19

Research at a Glance

Yale Co-Authors

Frequent collaborators of Vasilis Vasiliou's published research.

Publications

2024

2023

Academic Achievements & Community Involvement

  • activity

    Alcohol and Colon Cancer

  • activity

    Role of ALDHs in Diabetes

  • activity

    Structural/Chemical Biology of Aldehyde Dehydrogenases

Get In Touch

Contacts

Academic Office Number
Mailing Address

Environmental Health Sciences

60 College St.

New Haven, CT 06510

United States