Seamus Rooney, PhD
Professor Emeritus of Pediatrics (Neonatology)Cards
Contact Info
About
Titles
Professor Emeritus of Pediatrics (Neonatology)
Education & Training
- PhD
- Trinity College (1969)
Research
Research at a Glance
Yale Co-Authors
Frequent collaborators of Seamus Rooney's published research.
Publications Timeline
A big-picture view of Seamus Rooney's research output by year.
Robert Homer, MD, PhD
2Publications
67Citations
Publications
2003
Pulmonary surfactant secretion in briefly cultured mouse type II cells
Gobran LI, Rooney SA. Pulmonary surfactant secretion in briefly cultured mouse type II cells. American Journal Of Physiology - Lung Cellular And Molecular Physiology 2003, 286: l331-l336. PMID: 14565945, DOI: 10.1152/ajplung.00334.2003.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsMeSH KeywordsAdenosine TriphosphateAdenosine-5'-(N-ethylcarboxamide)AnimalsBronchodilator AgentsCarcinogensCells, CulturedFemaleIonomycinIonophoresLungMiceMice, Inbred C57BLPulmonary Surfactant-Associated Protein BPulmonary Surfactant-Associated Protein CTerbutalineTetradecanoylphorbol AcetateUridine TriphosphateVasodilator AgentsConceptsType II cellsII cellsSurfactant secretionRat type II cellsReceptor null miceStrains of miceSecretion of phosphatidylcholinePulmonary surfactant secretionFVB miceNull miceMiceSecretionSurfactant proteinsPhosphatidylcholine secretionTerbutalineSurfactant secretagoguesIonomycinCellsLittle informationSecretion of SPTPAResponseUTPC57BL/6Agonists
2002
Pulmonary type II cell hypertrophy and pulmonary lipoproteinosis are features of chronic IL-13 exposure
Homer RJ, Zheng T, Chupp G, He S, Zhu Z, Chen Q, Ma B, Hite RD, Gobran LI, Rooney SA, Elias JA. Pulmonary type II cell hypertrophy and pulmonary lipoproteinosis are features of chronic IL-13 exposure. American Journal Of Physiology - Lung Cellular And Molecular Physiology 2002, 283: l52-l59. PMID: 12060560, DOI: 10.1152/ajplung.00438.2001.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsMeSH KeywordsAnimalsAsthmaBronchoalveolar Lavage FluidGene ExpressionHypertrophyImmunohistochemistryInterleukin-13MiceMice, Inbred C57BLMice, Inbred CBAMice, TransgenicProteolipidsPulmonary AlveoliPulmonary FibrosisPulmonary Surfactant-Associated Protein APulmonary Surfactant-Associated ProteinsPulmonary SurfactantsRNA, MessengerConceptsType II cell hypertrophyIL-13Cell hypertrophyChronic pulmonary conditionsPathogenesis of asthmaBronchoalveolar lavage fluidTh2-mediated immunityIL-13 exposureProminent interstitial fibrosisWild-type miceAirway hyperresponsivenessMucus metaplasiaEosinophilic inflammationPulmonary diseaseInterstitial fibrosisLavage fluidPulmonary conditionsTwo- to threefold increaseSurfactant accumulationLittermate controlsPotent stimulatorSurfactant phospholipidsFibrosisKey mediatorHypertrophy