Sandra Abi Fadel, MD
Assistant Professor of Radiology and Biomedical ImagingDownloadHi-Res Photo
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Program Director of the Neuroradiology fellowship, Neuroradiology
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Are You a Patient?
View this doctor's clinical profile on the Yale Medicine website for information about the services we offer and making an appointment.
View Doctor ProfileAdditional Titles
Program Director of the Neuroradiology fellowship, Neuroradiology
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Are You a Patient?
View this doctor's clinical profile on the Yale Medicine website for information about the services we offer and making an appointment.
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Program Director of the Neuroradiology fellowship, Neuroradiology
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About
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Titles
Assistant Professor of Radiology and Biomedical Imaging
Program Director of the Neuroradiology fellowship, Neuroradiology
Biography
I am currently an assistant professor of Neuroradiology at Yale University.
I also serve as the Program Director of the Neuroradiology fellowship at Yale New Haven Hospital.
I did my diagnostic radiology residency training at the American University of Beirut, followed by a fellowship in Neuroradiology at Yale New Haven Hospital where I served as chief fellow.
Last Updated on November 04, 2025.
Appointments
Radiology & Biomedical Imaging
Assistant ProfessorPrimary
Other Departments & Organizations
- Clinical Radiology
- Neuroradiology
- Radiology & Biomedical Imaging
- Yale Medicine
Education & Training
- MD
- Yale New Haven Hospital, Diagnostic Radiology & Biomedical Imaging - Neuroradiology section (2020)
- Neuroradiology Fellow
- Yale New Haven Hospital (2020)
- Radiology Resident
- American University of Beirut (2019)
- MD
- Lebanese University, Faculty of Medical Sciences (2013)
Research
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Overview
TIPIC syndrome (TransIent Perivascular Inflammation of the Carotid syndrome).
New Gene Discovery with Whole Exome Sequencing in Pilomyxoid Astrocytoma in correlation with quantitative ADC analysis.
Medical Research Interests
Brain; Central Nervous System; Head; Neck; Nervous System Neoplasms; Parathyroid Glands; Pituitary Gland
ORCID
0000-0001-9562-4470
Research at a Glance
Yale Co-Authors
Frequent collaborators of Sandra Abi Fadel's published research.
Publications Timeline
A big-picture view of Sandra Abi Fadel's research output by year.
MingDe Lin, PhD
Amit Mahajan, MD
Antonio Omuro, MD
Richard Bronen, MD
Ami Rubinowitz, MD
Andrew Koo, MD
11Publications
78Citations
Publications
2025
Global gender representation in neurointerventional surgery: a natural language processing analysis of journal publications
Renedo D, Koo A, Amllay A, Sujijantarat N, Fathima B, Haynes J, Falcone G, Sheth K, Fadel S, Johnson M, Hebert R, Rivier C, Matouk C. Global gender representation in neurointerventional surgery: a natural language processing analysis of journal publications. Journal Of NeuroInterventional Surgery 2025, jnis-2025-023956. PMID: 40813072, DOI: 10.1136/jnis-2025-023956.Peer-Reviewed Original ResearchAltmetricConceptsNatural language processingNatural language processing methodsExtract metadataNatural language processing analysisLanguage processingArtificial intelligenceFemale last authorshipAcademic publishingAuthorship ratesFemale first authorshipAuthor affiliationJournal publicationsInstitutional affiliationFirst authorshipRepresentationSurgery journalsAPIAuthorshipProcess analysisMetadataFemale authorshipJournalsIntelligenceDecoding Erdheim–Chester Disease: a Pictorial Essay of the Radiologic and Pathologic Findings, and its Main Differential Diagnoses
de Oliveira Santo I, Lerner G, Rubinowitz A, Fadel S, Chen M, Mojibian H, Mathur M. Decoding Erdheim–Chester Disease: a Pictorial Essay of the Radiologic and Pathologic Findings, and its Main Differential Diagnoses. Clinical Radiology 2025, 85: 106873. PMID: 40215805, DOI: 10.1016/j.crad.2025.106873.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsErdheim-Chester diseaseManagement of Erdheim–Chester diseaseEvaluate disease extentMolecular mutation analysisClonal myeloid neoplasmsMonitoring Treatment ResponsePotential diagnostic pitfallsModern treatment strategiesPictorial essayDecades of lifeAffected organ systemsCentral nervous systemUnder-recognised conditionNonspecific presentationMyeloid neoplasmsDiagnostic suspicionDisease extentRadiological findingsTargeted therapyFoamy histiocytesClinical featuresPI3K-Akt pathwayDiagnostic pitfallsHistiocytic neoplasmsImaging findings
2023
Comparison of volumetric and 2D-based response methods in the PNOC-001 pediatric low-grade glioma clinical trial
von Reppert M, Ramakrishnan D, Brüningk S, Memon F, Fadel S, Maleki N, Bahar R, Avesta A, Jekel L, Sala M, Lost J, Tillmanns N, Kaur M, Aneja S, Kazerooni A, Nabavizadeh A, Lin M, Hoffmann K, Bousabarah K, Swanson K, Haas-Kogan D, Mueller S, Aboian M. Comparison of volumetric and 2D-based response methods in the PNOC-001 pediatric low-grade glioma clinical trial. Neuro-Oncology Advances 2023, 6: vdad172. PMID: 38221978, PMCID: PMC10785766, DOI: 10.1093/noajnl/vdad172.Peer-Reviewed Original ResearchCitationsAltmetric
2022
Spectrum of qualitative and quantitative imaging of pilomyxoid, intermediate pilomyxoid and pilocytic astrocytomas in relation to their genetic alterations
Fadel SA, von Reppert M, Kazarian E, Omay EZE, Marks A, Linder N, Hoffmann KT, Darbinyan A, Huttner A, Aboian MS. Spectrum of qualitative and quantitative imaging of pilomyxoid, intermediate pilomyxoid and pilocytic astrocytomas in relation to their genetic alterations. Neuroradiology 2022, 65: 195-205. PMID: 35984480, DOI: 10.1007/s00234-022-03027-3.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsPilocytic astrocytomaImaging characteristicsADC valuesAggressive imaging characteristicsSuprasellar pilocytic astrocytomaRecurrence/progressionPediatric brain tumorsFrontal white matterWhole-exome sequencingPilomyxoid astrocytomaIntraventricular extensionSuprasellar regionThird ventriclePosterior fossaAtypical locationBrain tumorsWhite matterGrade 1TumorsAstrocytomasDriver mutationsExome sequencingGenetic alterationsPatientsHippocampusIntegration of Machine Learning Into Clinical Radiology Practice – Development of a Machine Learning Tool for Preoperative Glioma Grade Prediction (P14-9.002)
Merkaj S, Zeevi T, Bousabarah K, Kazarian E, Lin M, Pala A, Petersen G, Jekel L, Bahar R, Tillmanns N, Cui J, Ikuta I, Bronen R, Fadel S, Westerhoff M, Omuro A, Aboian M. Integration of Machine Learning Into Clinical Radiology Practice – Development of a Machine Learning Tool for Preoperative Glioma Grade Prediction (P14-9.002). Neurology 2022, 98 DOI: 10.1212/wnl.98.18_supplement.3243.Peer-Reviewed Original ResearchSemi-Automated Longitudinal Lesion Tracking In PACS Reveals High Proportion of Metastatic Lesions Showing Mixed Response To Radiosurgery (P14-9.001)
Petersen G, Verma T, Bousabarah K, Jekel L, Merkaj S, Bahar R, Fadel S, Ikuta I, Lin M, Omuro A, Aboian M. Semi-Automated Longitudinal Lesion Tracking In PACS Reveals High Proportion of Metastatic Lesions Showing Mixed Response To Radiosurgery (P14-9.001). Neurology 2022, 98 DOI: 10.1212/wnl.98.18_supplement.3451.Peer-Reviewed Original ResearchReal-time PACS-integrated longitudinal brain metastasis tracking tool provides comprehensive assessment of treatment response to radiosurgery
Petersen G, Bousabarah K, Verma T, von Reppert M, Jekel L, Gordem A, Jang B, Merkaj S, Fadel S, Owens R, Omuro A, Chiang V, Ikuta I, Lin M, Aboian MS. Real-time PACS-integrated longitudinal brain metastasis tracking tool provides comprehensive assessment of treatment response to radiosurgery. Neuro-Oncology Advances 2022, 4: vdac116. PMID: 36043121, PMCID: PMC9412827, DOI: 10.1093/noajnl/vdac116.Peer-Reviewed Original ResearchCitationsAltmetricConceptsGamma KnifeTreatment responseBrain metastasis patientsFurther treatment planningNumber of lesionsMean followBrain metastasesMetastasis patientsMultiple lesionsDiagnostic followSingle patientStereotactic radiosurgeryPatientsLesionsIndividual lesionsPrevalenceAccurate surveillanceHeterogenous responseTreatment planningTreatmentFollowRadiosurgerySize assessmentComprehensive assessmentResponse
2021
OTHR-06. PACS Lesion Tracking Tool provides real time automatic information on brain tumor metastasis growth curves and RECIST criteria
Jang B, Lin M, Owens R, Bousabarah K, Mahajan A, Fadel S, Ikuta I, Tocino I, Aboian M. OTHR-06. PACS Lesion Tracking Tool provides real time automatic information on brain tumor metastasis growth curves and RECIST criteria. Neuro-Oncology Advances 2021, 3: iii15-iii15. DOI: 10.1093/noajnl/vdab071.061.Peer-Reviewed Original ResearchCitationsConceptsFirst brain MRIRECIST evaluationRECIST criteriaPatient managementBrain MRIResponse Evaluation CriteriaRadiology reportsBrain MRI studiesAdditional useful informationPost-gadolinium sequencesRECIST outcomeStable diseaseBrain metastasesClinical responsePartial responseProgressive diseaseComplete responseRadiologic impressionNew lesionsIntracranial metastasesClinical differencesTarget lesionsTreatment responseMRI studiesLesion sizeThe Utility of Imaging Parameters in Predicting Long-Term Clinical Improvement After Shunt Surgery in Patients with Idiopathic Normal Pressure Hydrocephalus
Subramanian HE, Fadel SA, Matouk CC, Zohrabian VM, Mahajan A. The Utility of Imaging Parameters in Predicting Long-Term Clinical Improvement After Shunt Surgery in Patients with Idiopathic Normal Pressure Hydrocephalus. World Neurosurgery 2021, 149: e1-e10. PMID: 33662608, DOI: 10.1016/j.wneu.2021.02.108.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsIdiopathic normal pressure hydrocephalusShunt surgeryNormal pressure hydrocephalusEvans indexCognitive improvementShunt placementPressure hydrocephalusImaging featuresLong-term patient-reported outcomesLong-term clinical improvementTelephone interviewsPreoperative imaging parametersVentriculoperitoneal shunt surgeryCerebrospinal fluid drainagePatient-reported outcomesLong-term outcomesLong-term cognitive improvementMagnetic resonance imagingImaging parametersClinical improvementGait improvementMedian durationClinical outcomesShunt candidatesFluid drainage
2020
LGG-09. CORRELATING GENETIC SIGNATURE OF PILOMYXOID ASTROCYTOMAS AND PILOCYTIC ASTROCYTOMAS WITH QUALITATIVE AND QUANTITATIVE MR IMAGING CHARACTERISTICS
Fadel S, Omay Z, Darbinyan A, Bronen R, Fulbright R, Mahajan A, Aboian M. LGG-09. CORRELATING GENETIC SIGNATURE OF PILOMYXOID ASTROCYTOMAS AND PILOCYTIC ASTROCYTOMAS WITH QUALITATIVE AND QUANTITATIVE MR IMAGING CHARACTERISTICS. Neuro-Oncology 2020, 22: iii367-iii368. PMCID: PMC7715503, DOI: 10.1093/neuonc/noaa222.392.Peer-Reviewed Original ResearchConceptsKIAA1549-BRAF fusionBRAF V600E mutationWhole-exome sequencingBRAF-wildtypePilocytic astrocytomaWildtype tumorsV600E mutationImaging characteristicsExome sequencingAtypical imaging featuresMR imaging characteristicsMyxoid featuresPediatric patientsPilomyxoid astrocytomaIntraventricular extensionImaging featuresIntratumoral hemorrhageMRI characteristicsGermline sequencingAtypical featuresT1 intensityTumor localizationWildtype BRAFKIAA1549-BRAFPA correlates
Academic Achievements & Community Involvement
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Activities
activity American Society of Spine Radiology
2019 - 2021CommitteesAbstract Graderactivity American Society of Neuroradiology
2019 - 2021Peer Review Groups and Grant Study SectionsRevieweractivity American Society of Spine Radiology
2019 - 2021CommitteesAward Committee Memberactivity American Society of Spine Radiology
2020 - 2021CommitteesMemberDetailsMember of the ASSR Social Media Committee
Honors
honor RSNA fellow research award
06/30/2020National AwardYale New Haven HospitalDetailsUnited Stateshonor Fellow of the year
06/30/2020Other AwardYale New Haven Hospital - NeuroradiologyDetailsUnited States
Clinical Care
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Overview
Sandra Abi Fadel, MD, is a neuroradiologist who performs imaging to diagnose conditions that affect the brain, spine and spinal cord, neck (including classification and grading of throat cancers), temporo-mandibular joints, and salivary glands. She uses multiple modalities, including X-ray, CT scan, and MRI, as well as such diagnostic and therapeutic procedures as guided lumbar puncture, myelography, and epidural blood patch.
“For me, the brain is the most important organ in our system. It makes us who we are,” Dr. Abi Fadel says. “I admire the brain anatomy and how every region in it is in charge of a specific function. Correlating patients’ neurological symptoms to specific anatomic regions in the brain and abnormalities on brain imaging is what I enjoy doing on daily basis.”
Using advanced imaging techniques to make a specific neurologic diagnosis can have an important impact on managing and treating a condition in a timely and effective manner, she adds. “We are on your side. Each and every one of us is a patient advocate in his or her own specialty.”
Clinical Specialties
Radiology & Biomedical Imaging; Neuroradiology
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