Robert Safirstein, MD
Professor Emeritus of Medicine (Nephrology)Cards
About
Research
Publications
2025
Acute kidney injury markers in pediatric pancreatitis: Differentiating disease states and assessing severity
Garlapally V, Guo X, Hornung L, Delgado K, Cruz‐Monserrate Z, Safirstein R, Gorelick F, Desir G, Goldstein S, Abu‐El‐Haija M. Acute kidney injury markers in pediatric pancreatitis: Differentiating disease states and assessing severity. Journal Of Pediatric Gastroenterology And Nutrition 2025, 82: 770-780. PMID: 41384696, PMCID: PMC13185510, DOI: 10.1002/jpn3.70285.Peer-Reviewed Original ResearchRenalase, HIV viremia, and all-cause mortality in people with and without HIV
Chang J, So-Armah K, Guo X, Kundu S, Safirstein R, Marconi V, Freiberg M, Brown S, Justice A, Desir G. Renalase, HIV viremia, and all-cause mortality in people with and without HIV. AIDS 2025, 39: 1490-1494. PMCID: PMC13089388, DOI: 10.1097/qad.0000000000004195.Peer-Reviewed Original Research
2023
APOBEC-1 deletion enhances cisplatin-induced acute kidney injury
Guo X, Blanc V, Davidson N, Velazquez H, Chen T, Moledina DG, Moeckel G, Safirstein R, Desir G. APOBEC-1 deletion enhances cisplatin-induced acute kidney injury. Scientific Reports 2023, 13: 22255. PMID: 38097707, PMCID: PMC10721635, DOI: 10.1038/s41598-023-49575-3.Peer-Reviewed Original ResearchmRNA Editing via the Apobec1 Gene Promotes Recovery from AKI
Guo X, Velazquez H, Xu L, Cheng Z, Chen T, Tian Y, Bewersdorf J, Blanc V, Davidson N, Safirstein R, Desir G. mRNA Editing via the Apobec1 Gene Promotes Recovery from AKI. Journal Of The American Society Of Nephrology 2023, 34: 451-451. DOI: 10.1681/asn.20233411s1451b.Peer-Reviewed Original ResearchRenalase Ameliorates AKI by Altering Mitochondrial Function to Induce Cellular Repair Mechanisms
Guo X, Chen R, Chen T, Safirstein R, Jonas E, Desir G. Renalase Ameliorates AKI by Altering Mitochondrial Function to Induce Cellular Repair Mechanisms. Journal Of The American Society Of Nephrology 2023, 34: 117-117. DOI: 10.1681/asn.20233411s1117b.Peer-Reviewed Original Research
2022
Apobec-1 Limits Cisplatin and Ischemia-Reperfusion-Induced AKI
Guo X, Xu L, Velazquez H, Chen T, Blanc V, Davidson N, Moeckel G, Safirstein R, Desir G. Apobec-1 Limits Cisplatin and Ischemia-Reperfusion-Induced AKI. Journal Of The American Society Of Nephrology 2022, 33: 359-360. DOI: 10.1681/asn.20223311s1359e.Peer-Reviewed Original ResearchRenalase Protects Renal Injury by Maintaining Mitochondrial Dynamic Homeostasis
Guo X, Chen R, Chen T, Moeckel G, Safirstein R, Jonas E, Desir G. Renalase Protects Renal Injury by Maintaining Mitochondrial Dynamic Homeostasis. Journal Of The American Society Of Nephrology 2022, 33: 359-359. DOI: 10.1681/asn.20223311s1359d.Peer-Reviewed Original ResearchEarly life body mass index trajectories and albuminuria in midlife: A 30-year prospective cohort study
Wang Y, Li F, Chu C, Zhang X, Zhang X, Liao Y, Du M, Zou T, Ma Q, Chen C, Wang D, Wang K, Yan Y, Sun Y, Hu G, Jia H, Li H, Niu Z, Yan R, Man Z, Wang L, Luo W, Zhang J, Li C, Lu W, Chang J, Safirstein R, Lu Y, Mu J. Early life body mass index trajectories and albuminuria in midlife: A 30-year prospective cohort study. EClinicalMedicine 2022, 48: 101420. PMID: 35516445, PMCID: PMC9065297, DOI: 10.1016/j.eclinm.2022.101420.Peer-Reviewed Original Research
2021
Heightened Innate Immune Response to COVID-19 Infection in CKD: Implications to Poorer Outcome During CKD
Guo X, Xu L, Chen T, Gorelick F, Desir G, Safirstein R. Heightened Innate Immune Response to COVID-19 Infection in CKD: Implications to Poorer Outcome During CKD. Journal Of The American Society Of Nephrology 2021, 32: 749-749. DOI: 10.1681/asn.20213210s1749c.Peer-Reviewed Original Research
2020
Kidney Targeted Renalase Agonist Peptide Rescues Severe Model of Cisplatin-Induced AKI and CKD
Guo X, Xu L, Velazquez H, Chen T, Williams R, Heller D, Safirstein R, Desir G. Kidney Targeted Renalase Agonist Peptide Rescues Severe Model of Cisplatin-Induced AKI and CKD. Journal Of The American Society Of Nephrology 2020, 31: 230-230. DOI: 10.1681/asn.20203110s1230b.Peer-Reviewed Original Research