Rafael Ricci de Azevedo
Associate Research ScientistCards
About
Research
Publications
2026
IL15-mediated crosstalk between LSECs and CD8⁺ tissue-resident memory T cells drives alcohol-associated hepatitis
Zhong W, Ricci-Azevedo R, Wang S, Cooper S, Ma J, Swartzwelter B, Xhafi F, Zhao D, Gao H, Shah V, Liangpunsakul S, Ouyang X, Mehal W, Cao S, Sun Z, Peiffer B, Iwakiri Y, Vassallo R, Liu M. IL15-mediated crosstalk between LSECs and CD8⁺ tissue-resident memory T cells drives alcohol-associated hepatitis. Hepatology Communications 2026, 10: e0967. PMID: 42275578, PMCID: PMC13263083, DOI: 10.1097/hc9.0000000000000967.Peer-Reviewed Original ResearchRedefining Shiga toxin–induced human cell death as NLRP1- and gasdermin E-mediated pyroptosis
Ricci-Azevedo R, Sarkar B, Shivcharan S, Hazra A, Browne M, Carlson E, Chidambaram U, Rathinam V, Vanaja S. Redefining Shiga toxin–induced human cell death as NLRP1- and gasdermin E-mediated pyroptosis. Proceedings Of The National Academy Of Sciences Of The United States Of America 2026, 123: e2510274123. PMID: 41533439, PMCID: PMC12818423, DOI: 10.1073/pnas.2510274123.Peer-Reviewed Original Research
2025
RNA N-glycosylation enables immune evasion and homeostatic efferocytosis
Graziano V, Porat J, Ah Kioon M, Mejdrová I, Matz A, Lebedenko C, Chai P, Pluvinage J, Ricci-Azevedo R, Harrison A, Wright S, Wang X, Strine M, Wang P, Wilson M, Vanaja S, Zhou B, Barrat F, Carell T, Flynn R, Rathinam V. RNA N-glycosylation enables immune evasion and homeostatic efferocytosis. Nature 2025, 645: 784-792. PMID: 40770106, PMCID: PMC12845878, DOI: 10.1038/s41586-025-09310-6.Peer-Reviewed Original Research
2024
The recombinant l-lysine α-oxidase from the fungus Trichoderma harzianum promotes apoptosis and necrosis of leukemia CD34 + hematopoietic cells
Costa M, Silva T, Guimarães D, Ricci-Azevedo R, Teixeira F, Silveira L, Gomes M, Faça V, de Oliveira E, Calado R, Silva R. The recombinant l-lysine α-oxidase from the fungus Trichoderma harzianum promotes apoptosis and necrosis of leukemia CD34 + hematopoietic cells. Microbial Cell Factories 2024, 23: 51. PMID: 38355518, PMCID: PMC10865671, DOI: 10.1186/s12934-024-02315-2.Peer-Reviewed Original Research
2023
A bacterial autotransporter impairs innate immune responses by targeting the transcription factor TFE3
Ta A, Ricci-Azevedo R, Vasudevan S, Wright S, Kumari P, Havira M, Surendran Nair M, Rathinam V, Vanaja S. A bacterial autotransporter impairs innate immune responses by targeting the transcription factor TFE3. Nature Communications 2023, 14: 2035. PMID: 37041208, PMCID: PMC10090168, DOI: 10.1038/s41467-023-37812-2.Peer-Reviewed Original Research
2021
Microneme Proteins 1 and 4 From Toxoplasma gondii Induce IL-10 Production by Macrophages Through TLR4 Endocytosis
Ricci-Azevedo R, Mendonça-Natividade F, Santana A, Diniz J, Roque-Barreira M. Microneme Proteins 1 and 4 From Toxoplasma gondii Induce IL-10 Production by Macrophages Through TLR4 Endocytosis. Frontiers In Immunology 2021, 12: 655371. PMID: 33912181, PMCID: PMC8071938, DOI: 10.3389/fimmu.2021.655371.Peer-Reviewed Original ResearchProtein methyltransferase 7 deficiency in Leishmania major increases neutrophil associated pathology in murine model
Diniz J, Chaves M, Vaselek S, Magalhães R, Ricci-Azevedo R, de Carvalho R, Lorenzon L, Ferreira T, Zamboni D, Walrad P, Volf P, Sacks D, Cruz A. Protein methyltransferase 7 deficiency in Leishmania major increases neutrophil associated pathology in murine model. PLOS Neglected Tropical Diseases 2021, 15: e0009230. PMID: 33651805, PMCID: PMC7954300, DOI: 10.1371/journal.pntd.0009230.Peer-Reviewed Original Research
2020
Paracoccin Overexpression in Paracoccidioides brasiliensis Enhances Fungal Virulence by Remodeling Chitin Properties of the Cell Wall
Gonçales R, Ricci-Azevedo R, Vieira V, Fernandes F, de O Thomaz S, Carvalho A, Vendruscolo P, Cunha C, Roque-Barreira M, Rodrigues F. Paracoccin Overexpression in Paracoccidioides brasiliensis Enhances Fungal Virulence by Remodeling Chitin Properties of the Cell Wall. Journal Of Infectious Diseases 2020, 224: 164-174. PMID: 33201217, DOI: 10.1093/infdis/jiaa707.Peer-Reviewed Original ResearchMIC4 from Toxoplasma gondii: A Lectin Acting as a Toll-Like Receptor Agonist
Costa Mendonça-Natividade F, Ricci-Azevedo R, Roque-Barreira M. MIC4 from Toxoplasma gondii: A Lectin Acting as a Toll-Like Receptor Agonist. Methods In Molecular Biology 2020, 2132: 379-389. PMID: 32306345, DOI: 10.1007/978-1-0716-0430-4_37.ChaptersProduction and Characterization of MIC1: A Lectin from Toxoplasma gondii
Costa Mendonça-Natividade F, Ricci-Azevedo R, de Oliveira Thomaz S, Roque-Barreira M. Production and Characterization of MIC1: A Lectin from Toxoplasma gondii. Methods In Molecular Biology 2020, 2132: 391-400. PMID: 32306346, DOI: 10.1007/978-1-0716-0430-4_38.Chapters