Philip Sarrel, MD
Professor Emeritus of Obstetrics, Gynecology, and Reproductive SciencesCards
Titles
Professor Emeritus of Psychiatry
Contact Info
About
Titles
Professor Emeritus of Obstetrics, Gynecology, and Reproductive Sciences
Professor Emeritus of PsychiatryEducation & Training
- Residency
- Yale School of Medicine (1967)
- MD
- New York University (1964)
Board Certifications
Obstetrics & Gynecology
- Certification Organization
- AB of Obstetrics & Gynecology
- Original Certification Date
- 1969
Research
Research at a Glance
Yale Co-Authors
Frequent collaborators of Philip Sarrel's published research.
Publications Timeline
A big-picture view of Philip Sarrel's research output by year.
Catherine Viscoli, PhD
Walter Kernan, MD
7Publications
374Citations
Publications
2024
Navigating menopause at work: a preliminary study about challenges and support systems
Alzueta E, Menghini L, Volpe L, Baker F, Garnier A, Sarrel P, de Zambotti M. Navigating menopause at work: a preliminary study about challenges and support systems. Menopause The Journal Of The North American Menopause Society 2024, 31: 258-265. PMID: 38442310, DOI: 10.1097/gme.0000000000002333.Peer-Reviewed Original ResearchAltmetricConceptsSeverity of menopausal symptomsMenopausal symptomsEmotional exhaustionCross-sectional surveyHierarchical multiple regression modelWork-related challengesWorking womenPeri-menopausal womenTurnover intentionEffective workforceMultiple regression modelWorkforce participationWell-beingIncreased awarenessRegression modelsJob demands-resources modelWorkplace measuresWomenDemands-resources modelMenopauseWork settingsParticipantsSymptomsUnited StatesRespondents
2015
Incremental direct and indirect costs of untreated vasomotor symptoms
Sarrel P, Portman D, Lefebvre P, Lafeuille MH, Grittner AM, Fortier J, Gravel J, Duh MS, Aupperle PM. Incremental direct and indirect costs of untreated vasomotor symptoms. Menopause The Journal Of The North American Menopause Society 2015, 22: 260-266. PMID: 25714236, DOI: 10.1097/gme.0000000000000320.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsHealthcare resource utilizationVasomotor symptomsOutpatient visitsIndirect costsHigher healthcare resource utilizationRetrospective matched-cohort studyIncremental indirect costsMatched-cohort studySevere vasomotor symptomsCause outpatient visitsHealth insurance claimsControl womenControl cohortLoss daysMost womenWork lossPropensity scoreWomenDirect costsVisitsCost burdenPatientsCohortSymptomsProductivity loss
2013
The mortality toll of estrogen avoidance: an analysis of excess deaths among hysterectomized women aged 50 to 59 years.
Sarrel PM, Njike VY, Vinante V, Katz DL. The mortality toll of estrogen avoidance: an analysis of excess deaths among hysterectomized women aged 50 to 59 years. American Journal Of Public Health 2013, 103: 1583-8. PMID: 23865654, PMCID: PMC3780684, DOI: 10.2105/ajph.2013.301295.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsEstrogen therapyHysterectomized womenEstrogen usePostmenopausal womenMortality tollHealth initiativesEffects of ETYounger postmenopausal womenWomen's Health InitiativeHealth care providersCause mortalityExcess mortalityCare providersMortality rateExcess deathsComparable womenWomenThousands of womenMortalityEntire populationYearsInformed discussionTherapyPopulationTrials
2005
Medroxyprogesterone acetate and dihydrotestosterone induce coronary hyperreactivity in intact male rhesus monkeys.
Mishra RG, Hermsmeyer RK, Miyagawa K, Sarrel P, Uchida B, Stanczyk FZ, Burry KA, Illingworth DR, Nordt FJ. Medroxyprogesterone acetate and dihydrotestosterone induce coronary hyperreactivity in intact male rhesus monkeys. The Journal Of Clinical Endocrinology & Metabolism 2005, 90: 3706-14. PMID: 15769993, PMCID: PMC1473190, DOI: 10.1210/jc.2004-1557.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsIntact male rhesus monkeysTP receptor expressionCoronary hyperreactivityVascular muscle cellsReceptor expressionMale rhesus monkeysAndrogen receptorEpicardial coronariesP receptorRhesus monkeysMuscle cellsAR antagonist flutamideProstanoid receptor expressionMedroxyprogesterone acetate treatmentAdult male primatesBrief vasoconstrictionDHT inductionIntracoronary serotoninVasoconstrictor challengesCoronary arteryMedroxyprogesterone acetateSevere vasoconstrictionAnalogue U46619Myocardial ischemiaDihydrotestosterone exposureEstrogen therapy and risk of cognitive decline: Results from the Women's Estrogen for Stroke Trial (WEST)
Viscoli CM, Brass LM, Kernan WN, Sarrel PM, Suissa S, Horwitz RI. Estrogen therapy and risk of cognitive decline: Results from the Women's Estrogen for Stroke Trial (WEST). American Journal Of Obstetrics And Gynecology 2005, 192: 387-393. PMID: 15695976, DOI: 10.1016/j.ajog.2004.08.017.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsMini-Mental State ExaminationEstrogen therapyCognitive declineNormal Mini-Mental State ExaminationDouble-blind trialSecondary stroke preventionTransient ischemic attackIschemic attackPostmenopausal womenStroke preventionRecent strokeStroke trialsCerebrovascular diseaseWomen's EstrogenEstradiol-17betaState ExaminationCognitive measuresEstrogenWomenNormal functionDomain measuresLess declineTherapyStrokeRisk
2003
Raloxifene and endothelial function in healthy postmenopausal women
Sarrel PM, Nawaz H, Chan W, Fuchs M, Katz DL. Raloxifene and endothelial function in healthy postmenopausal women. American Journal Of Obstetrics And Gynecology 2003, 188: 304-309. PMID: 12592230, DOI: 10.1067/mob.2003.28.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsPostmenopausal womenEndothelial functionPlacebo-controlled crossover trialEndothelial-mediated dilationLaser Doppler measuresEffects of raloxifeneFlow-mediated dilationHealthy postmenopausal womenBrachial artery diameter changesArtery diameter changesWarrants further studyBrachial arteryCardioprotective effectsCrossover trialDoppler measuresCurve ratioHyperemic stimulusRaloxifenePlaceboStimulus intensityDigital vesselsPotential mechanismsRatio of areaWomenFurther studies
2002
Androgen deficiency: menopause and estrogen-related factors
Sarrel PM. Androgen deficiency: menopause and estrogen-related factors. Fertility And Sterility 2002, 77: 63-67. PMID: 12007905, DOI: 10.1016/s0015-0282(02)02967-9.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsHormone replacement therapyEffects of androgensPostmenopausal womenReplacement therapyEndogenous androgensPostmenopausal hormone replacement therapySex hormone-binding globulinAddition of androgensHormone-binding globulinMenopause-related symptomsAction of estrogenAcademic medical centerAndrogen bioavailabilityEstrogen replacementSymptom controlOvarian hormonesAndrogen replacementBone lossEstrogen depletionMenopausal womenNatural menopauseSexual functionMedical CenterAndrogen effectsEstradiol depletion
Academic Achievements and Community Involvement
honor Elm and Ivy Award, 1982
Yale University AwardYale and the City of New HavenDetails06/01/1982United Stateshonor Macy Foundation Faculty Scholar
National AwardMacy FoundationDetails07/01/1975United States
Links & Media
News
- October 30, 2015
Stopping a Zombie: The Truth about Estrogen and Heart Disease
- August 27, 2014
The high cost of hot flashes in menopause
- August 27, 2014
The high cost of hot flashes: Millions in lost wages preventable
- July 19, 2013
Estrogen still may be a lifesaver after a hysterectomy