Oluwole Jegede, MD, MPH, PhD

Dr. Jegede’s research program focuses on the cultural adaptation and equitable implementation of evidence-based interventions for stimulant use disorders within racially and ethnically minoritized populations. His work employs mixed-methods and hybrid effectiveness–implementation designs to examine how contextual and structural factors influence intervention uptake, fidelity, and sustainability in real-world community and safety-net settings. Guided by principles of community engagement and community-based participatory research (CBPR), he collaborates closely with community advisory boards, persons with lived experience, and frontline clinicians to ensure that adapted interventions reflect the priorities, values, and lived realities of the populations they serve. Through equity-oriented evaluation frameworks, his studies seek to enhance both the cultural responsiveness and structural competence of addiction treatment models.

In parallel, Dr. Jegede leads and contributes to interdisciplinary research at the intersection of digital health, machine learning, and algorithmic fairness. This work investigates how social and structural stressors can be integrated into predictive psychiatric models to reduce bias and improve representativeness in clinical decision-making tools. Central to his scientific agenda is the conceptualization of social determinants of health as social biomarkers of structural vulnerability—an approach that bridges implementation science, health equity research, and computational psychiatry. Collectively, his scholarship advances an equity-centered addiction science framework designed to inform the development of integrated, culturally responsive, and structurally competent models of care that improve engagement and outcomes among historically marginalized populations.