Mark Iscoe, MD, MHS
Assistant Professor of Emergency Medicine and Biomedical Informatics and Data ScienceCards
About
Research
Publications
2026
Correction: Real-World Evidence Synthesis of Digital Scribes Using Ambient Listening and Generative Artificial Intelligence for Clinician Documentation Workflows: Rapid Review
Kanaparthy N, Villuendas-Rey Y, Bakare T, Diao Z, Iscoe M, Loza A, Wright D, Safranek C, Faustino I, Brackett A, Melnick E, Taylor R. Correction: Real-World Evidence Synthesis of Digital Scribes Using Ambient Listening and Generative Artificial Intelligence for Clinician Documentation Workflows: Rapid Review. JMIR AI 2026, 5: e93250. PMID: 41824620, PMCID: PMC12986773, DOI: 10.2196/93250.Peer-Reviewed Original ResearchBoard Examination Pass Rates of Emergency Medicine Residency Training Programs: Associations With Founding Year, Teaching Status, Length, and Hospital Ownership
Topping C, Venkatesh A, Rothenberg C, Goldflam K, Carter W, Chung A, Siegelman J, Sangal R, Iscoe M, Ulrich A, Gettel C. Board Examination Pass Rates of Emergency Medicine Residency Training Programs: Associations With Founding Year, Teaching Status, Length, and Hospital Ownership. AEM Education And Training 2026, 10: e70144. PMID: 41798586, PMCID: PMC12964488, DOI: 10.1002/aet2.70144.Peer-Reviewed Original ResearchCouncil of Teaching HospitalsEM residency programsEmergency medicineHospital ownershipFor-profit hospitalsCOTH hospitalsAmerican Hospital Association dataAmerican Board of Emergency MedicineResidency programsObservational cross-sectional analysisProgram lengthProgram characteristicsAmerican BoardGraduate Medical EducationCross-sectional analysisCertification pass ratePass rateHigher pass rateEM residentsQualifying examTeaching statusLinear regression modelsMedical educationFour-year programBoard examination performanceEmergency Physicians' Electronic Health Record Use and High-Risk Unscheduled Return Visits: A Case-Control Study
Iscoe M, Feit B, Venkatesh A, Holland M, Melnick E. Emergency Physicians' Electronic Health Record Use and High-Risk Unscheduled Return Visits: A Case-Control Study. Journal Of Emergency Medicine 2026 DOI: 10.1016/j.jemermed.2026.02.039.Peer-Reviewed Original ResearchElectronic health recordsED visitsAssociated with oddsUnscheduled returnsEHR timeRetrospective case-control studyUnscheduled return visitsChief complaintSingle health systemEHR useED qualityHealth recordsNight arrivalHealth systemED dischargeIndex visitStudy of adult patientsHigh-risk groupCharlson Comorbidity IndexHospital admissionReturn visitsInclusion criteriaAcuity scoresLogistic regressionCase-control study of adult patientsHigh-Risk Medication Prescriptions Among Older Adults Discharged from the Emergency Department
Iscoe M, Sangal R, Hwang U, Fried T, Meeker D, Conner T, Gettel C, Follman S, Wright D, Venkatesh A. High-Risk Medication Prescriptions Among Older Adults Discharged from the Emergency Department. JAMA Internal Medicine 2026, 186 PMID: 41661555, PMCID: PMC12887836, DOI: 10.1001/jamainternmed.2025.7883.Peer-Reviewed Original Research
2025
Beyond Right and Wrong: The Diagnostic Calibration Matrix and Decision Latitude as a Tiered Framework for Evaluating Diagnostic Reasoning
Pavuluri S, Sangal R, Taylor R, Iscoe M, Venkatesh A, Sather J. Beyond Right and Wrong: The Diagnostic Calibration Matrix and Decision Latitude as a Tiered Framework for Evaluating Diagnostic Reasoning. Academic Emergency Medicine 2025, 33: e70193. PMID: 41225307, DOI: 10.1111/acem.70193.Peer-Reviewed Original ResearchReal-World Evidence Synthesis of Digital Scribes Using Ambient Listening and Generative Artificial Intelligence for Clinician Documentation Workflows: Rapid Review
Kanaparthy N, Villuendas-Rey Y, Bakare T, Diao Z, Iscoe M, Loza A, Wright D, Safranek C, Faustino I, Brackett A, Melnick E, Taylor R. Real-World Evidence Synthesis of Digital Scribes Using Ambient Listening and Generative Artificial Intelligence for Clinician Documentation Workflows: Rapid Review. JMIR AI 2025, 4: e76743. PMID: 41071988, PMCID: PMC12513689, DOI: 10.2196/76743.Peer-Reviewed Original ResearchStranded in the emergency department: an analysis of boarding trends in older adults in the United States
Sifnugel N, Jeffery M, Grogan E, Sangal R, Carr B, Cruz D, Dresden S, Gettel C, Iscoe M, Skains R, Venkatesh A, Hwang U. Stranded in the emergency department: an analysis of boarding trends in older adults in the United States. Health Affairs Scholar 2025, 3: qxaf187. PMID: 41143086, PMCID: PMC12548728, DOI: 10.1093/haschl/qxaf187.Peer-Reviewed Original ResearchOlder adultsHealth systemDiverse hospital typesQuality improvement initiativesHigher risk of hospitalizationClinical administrative dataCross-sectional analysisHigh riskRisk of hospitalizationAdmission pathwayHospital typeImprovement initiativesHospital boardsAdministrative dataHospital bedsEmergency departmentGreater riskAging populationCognitive declineNHAMCSOlder patientsAdultsHealthNegative outcomesHospitalA Measurement Science Framework to Optimize CDS for Opioid Use Disorder Treatment in the ED
Iscoe M, Hooper C, Levy D, Lutz J, Paek H, Rose C, Kannampallil T, Meeker D, Dziura J, Melnick E. A Measurement Science Framework to Optimize CDS for Opioid Use Disorder Treatment in the ED. Applied Clinical Informatics 2025, 16: 1067-1076. PMID: 40834872, PMCID: PMC12431813, DOI: 10.1055/a-2595-0317.Peer-Reviewed Original ResearchConceptsClinical decision supportEmergency departmentED initiationOpioid use disorderScience FrameworkClinical decision support applicationsEmergency department-initiated buprenorphineUse disorderSingle health systemInitiation of buprenorphineOpioid use disorder treatmentWorking group sessionsHealth systemGroup sessionsEligible encountersCo-design processMultidisciplinary partnersCo-designPostmeeting surveysCDS performancePriority categoriesAHRQConsensus methodologyFinal measurementBuprenorphine initiationEmergency Department Implementation of a Multimodal Electronic Health Record–Integrated Clinical Intervention for High-Sensitivity Troponin Testing Increases Diagnostic Efficiency
Sangal R, Iscoe M, Rothenberg C, Possick S, Taylor R, Safdar B, Desai N, Rhodes D, Venkatesh A. Emergency Department Implementation of a Multimodal Electronic Health Record–Integrated Clinical Intervention for High-Sensitivity Troponin Testing Increases Diagnostic Efficiency. Journal Of The American College Of Emergency Physicians Open 2025, 6: 100202. PMID: 40606317, PMCID: PMC12214263, DOI: 10.1016/j.acepjo.2025.100202.Peer-Reviewed Original ResearchEmergency departmentAcute myocardial infarction diagnosisTroponin testingED dischargeMyocardial infarction diagnosisAssociated with lower oddsAccelerated diagnostic protocolPhysician practice variationAcute coronary syndromeInfarction diagnosisChest pain evaluationMultivariate logistic regressionSuspected acute coronary syndromePostintervention periodDownstream testingPhysician practicesPreintervention periodED dispositionLower oddsCoronary syndromeDecreased oddsIncreased oddsPractice variationED patientsHs-cTnTCase Report: A health system’s experience using clinical decision support to promote note sharing after the 21st Century Cures Act
Iscoe M, Venkatesh A, Powers E, Kashyap N, Hsiao A, Millard H, Sangal R. Case Report: A health system’s experience using clinical decision support to promote note sharing after the 21st Century Cures Act. JAMIA Open 2025, 8: ooaf051. PMID: 40510806, PMCID: PMC12161449, DOI: 10.1093/jamiaopen/ooaf051.Peer-Reviewed Original ResearchClinical decision supportHealth system's experienceRegional health systemDecision supportPatient engagementCentury Cures ActHealth systemPortal accessClinical notesConsistent with prior research showingCures ActPromote complianceSensitive informationStudy periodLinear regressionPediatricObservational analysisPsychiatryPatients/proxiesNotesPatientsSupportHealthCliniciansResearch show
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