Lester Rodriguez Santos, BSc (Hon)
About
Titles
PhD Candidate , Interdepartmental Neuroscience Program
Biography
Lester earned a B.S. in Cellular and Molecular Biology from the University of Puerto Rico, Río Piedras Campus in San Juan, Puerto Rico. As an undergraduate, he conducted research using pre-clinical rodent models to investigate the role of endocannabinoids in regulating anxiety-like behaviors.
Following graduation, he joined the Neuroimaging Research Branch at the National Institute on Drug Abuse as a postbaccalaureate fellow under the mentorship of Dr. Elliot Stein. His work focused on examining alterations in functional connectivity during acute nicotine abstinence in smokers.
At Yale, Lester is co-mentored by Dr. Sarah W Yip and Dr. Kelly Cosgrove. His research focuses on examining how acute stimulant drug administration affects brain function and behavior, using functional magnetic resonance imaging (fMRI) and positron emission tomography (PET).
In addition to his research, Lester is committed to scientific outreach and education. He currently serves as Director of OpenLabs at Yale, a student-led initiative that hosts science outreach events on campus each semester. He also serves as Outreach Co-Chair for the Wu Tsai Institute’s Student, Postbac, and Postdoc Collective (SPPC), where he developed an annual Neuroscience and Cognition Bootcamp for local high school students. These efforts led to his receiving the 2025 Public Service Award from the Graduate School of Arts and Sciences for Disciplinary Outreach.
Education & Training
- BSc (Hon)
- University of Puerto Rio - Rio Piedras Campus, Cellular and Molecular Biology (2020)
Research
Overview
- Explore the effects of acute stimulant drug administration on functional connectivity in healthy adults with resting-state fMRI.
- Link stimulant-induced alterations of functional connectivity to dopamine release through PET imaging.
- Identify biomarkers of stimulant misuse vulnerability.
Medical Research Interests
Public Health Interests
Academic Achievements & Community Involvement
News & Links
#CientificosAlServicio en Línea: Neuroimagen para estudiar la función del cerebro humano
CienciaPR Seminar February 2025
Media
#CientificosAlServicio en Línea: Neuroimagen para estudiar la función del cerebro humano
CienciaPR Seminar February 2025
Learning How we Can Follow Brain Activity with MRI with Lester Rodriguez
OpenLabs ay Yale Science Cafe Talk Fall 2022
Mind Readers: Studying the Brain in Humans with Lester Rodriguez
OpenLabs at Yale Exploring Science Seminar Spring 2024
News
Get In Touch
Contacts
Locations
Cosgrove Lab - Yale Translational Brain Imaging Program
Lab
Temple Medical Center
40 Temple Street
New Haven, CT 06510
Yale Imaging & Psychopharmacology (YIP) Lab
Lab
1 Church Street
New Haven, CT 06510