Joseph Lucien Goulet, PhD, MS
Cards
Appointments
Additional Titles
Consultant for Observational Studies, Yale Center for Analytical Sciences (YCAS)
Director, Methods Core, Pain Research, Informatics, Multimorbidities, and Education (PRIME) Center, VA Connecticut Healthcare System
Director, Research Design Clinic, Pain Research, Informatics, Multimorbidities, and Education (PRIME) Center, VA Connecticut Healthcare System
Contact Info
Yale University
950 Campbell Ave, Bldg 35a
West Haven, CT 06516
United States
Appointments
Additional Titles
Consultant for Observational Studies, Yale Center for Analytical Sciences (YCAS)
Director, Methods Core, Pain Research, Informatics, Multimorbidities, and Education (PRIME) Center, VA Connecticut Healthcare System
Director, Research Design Clinic, Pain Research, Informatics, Multimorbidities, and Education (PRIME) Center, VA Connecticut Healthcare System
Contact Info
Yale University
950 Campbell Ave, Bldg 35a
West Haven, CT 06516
United States
Appointments
Additional Titles
Consultant for Observational Studies, Yale Center for Analytical Sciences (YCAS)
Director, Methods Core, Pain Research, Informatics, Multimorbidities, and Education (PRIME) Center, VA Connecticut Healthcare System
Director, Research Design Clinic, Pain Research, Informatics, Multimorbidities, and Education (PRIME) Center, VA Connecticut Healthcare System
Contact Info
Yale University
950 Campbell Ave, Bldg 35a
West Haven, CT 06516
United States
About
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Titles
Professor Emeritus in Emergency Medicine
Consultant for Observational Studies, Yale Center for Analytical Sciences (YCAS)
Positions outside Yale
Director, Methods Core, Pain Research, Informatics, Multimorbidities, and Education (PRIME) Center, VA Connecticut Healthcare System; Director, Research Design Clinic, Pain Research, Informatics, Multimorbidities, and Education (PRIME) Center, VA Connecticut Healthcare System
Biography
I am interested in health services research focusing on Veterans with psychiatric and medical comorbidity. My specific interests include research on: the prognostic significance of comorbidity among people with HIV, the ‘clustering’ of comorbid diseases and conditions, and the treatment of chronic pain among patients with current or pre-existing substance use disorders.
Appointments
Emergency Medicine
EmeritusPrimaryEmergency Medicine
Senior Research ScientistSecondary
Other Departments & Organizations
- Center for Interdisciplinary Research on AIDS
- Emergency Medicine
- Pain Research, Informatics, Multimorbidities, and Education (PRIME) Center
- Yale Medicine Outlist
- Yale Ventures
Education & Training
- NIDA Pre-Doctoral Fellow
- Yale School of Public Health (2003)
- PhD
- Yale University, Epidemiology (2003)
- MS
- Southern Connecticut State University, Statistics (1992)
- BS
- Southern Connecticut State University, Psychology (1989)
Research
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Overview
I am the Director of the Methodology and Biostatistics core of the VA’s Pain Research, Informatics, Multi-morbidities, and Education (PRIME) HSR&D Center of Innovation, and PI of VA funded administrative data-based studies including the Musculoskeletal Diagnoses Cohort: Examining Pain and Pain Care in the VA. My research interests focus on the impact of mental health disorders on the course of care and outcomes for Veterans with comorbid medical conditions. I have extensive experience applying advanced statistical methods to answer health services related questions using VA administrative and clinical data sources. My statistical interests are in longitudinal analysis, latent-class models, and clustering algorithms. I have been involved in the design and conduct of several large-scale cohort studies of Veterans using VA data sources supplemented by patient surveys on topics including Complementary Health, HIV, women Veteran’s health, and musculoskeletal disorders. Projects that I lead or am co-investigator on include: the Musculoskeletal Disorders cohort which examines demographic, clinical, temporal, and geographic variation in pain and pain treatment; the Women Veterans Cohort Study, which seeks to identify factors associated with gender disparities in health care utilization and outcomes among OEF/OIF/OND Veterans in the VA system; and the Veterans Aging Cohort Study, a prospective, observational cohort study of HIV- positive and age/race/site matched control group of HIV- negative veterans in VA care. I will participate in Dr. Karras’ project as an expert in observational data analysis. My experience working with a diverse group of VA and affiliated researchers for nearly 20 years in the analysis of such data to answer health services and clinical questions makes me well suited to this role. I have contributed to the conceptual and empirical literature of relevance to the study. I will ensure that the research agenda is informed by the most relevant and up-to-date statistical methodology.
Medical Research Interests
ORCID
0000-0002-0842-804X- View Lab Website
Pain Research, Informatics, Medical comorbidities, and Education (PRIME) Center
Research at a Glance
Yale Co-Authors
Publications Timeline
Research Interests
Amy Justice, MD, PhD
Robert Kerns, PhD
Cynthia Brandt, MD, MPH
Harini Bathulapalli
Kirsha Gordon, PhD, MS
Mary Driscoll, PhD
Veterans
Mental Disorders
Comorbidity
Longitudinal Studies
Algorithms
Health Services Research
Publications
2025
Incident Atherosclerotic Cardiovascular Disease Among Veterans by Gender Identity: A Cohort Study
Streed C, Duncan M, Heier K, Workman T, Beach L, Jasuja G, Wolfe H, Hughes L, O’Leary J, Skanderson M, Goulet J. Incident Atherosclerotic Cardiovascular Disease Among Veterans by Gender Identity: A Cohort Study. Journal Of General Internal Medicine 2025, 1-10. PMID: 40601199, DOI: 10.1007/s11606-025-09701-5.Peer-Reviewed Original ResearchCitationsAltmetricConceptsGender-affirming hormone therapyIncident atherosclerotic cardiovascular diseaseGender identityCisgender menCisgender womenAtherosclerotic cardiovascular disease outcomesAtherosclerotic cardiovascular diseaseGender-affirming careInternational Classification of Diseases diagnosisCisgender veteransVeterans Health AdministrationTrans populationsPrevalent atherosclerotic cardiovascular diseasesSexual orientationCardiovascular diseaseCox proportional hazards regressionProportional hazards regressionHealth AdministrationInternational ClassificationAssociated with atherosclerotic cardiovascular diseaseHispanic ethnicityGenderCohort studyHazards regressionElevated riskThe Impact of Chiropractic Care on Opioid Prescriptions in Veterans Health Administration Patients Receiving Low Back Pain Care
Lisi A, Bastian L, Brandt C, Coleman B, Fenton B, King J, Goulet J. The Impact of Chiropractic Care on Opioid Prescriptions in Veterans Health Administration Patients Receiving Low Back Pain Care. Journal Of General Internal Medicine 2025, 1-9. PMID: 40394439, DOI: 10.1007/s11606-025-09556-w.Peer-Reviewed Original ResearchCitationsAltmetricConceptsLow back painPrimary care providersVeterans Health AdministrationChiropractic careOpioid prescriptionsCare usersLow back pain careLow back pain visitsVA primary care providersElectronic health record dataVeterans Health Administration patientsBack pain careDesignCross-sectional analysisHealth record dataReceipt of opioid prescriptionsPain careCare providersPropensity-matched sampleFollow-upBack painHealthcare servicesVHA patientsHealth AdministrationVA patientsPotential confoundersIdentifying Patient-Reported Outcome Measure Documentation in Veterans Health Administration Chiropractic Clinic Notes: Natural Language Processing Analysis
Coleman B, Corcoran K, Brandt C, Goulet J, Luther S, Lisi A. Identifying Patient-Reported Outcome Measure Documentation in Veterans Health Administration Chiropractic Clinic Notes: Natural Language Processing Analysis. JMIR Medical Informatics 2025, 13: e66466. PMID: 40173367, PMCID: PMC12038758, DOI: 10.2196/66466.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsPatient-reported outcome measuresVeterans Health AdministrationChiropractic careNatural language processingPROM useNatural language processing approachCare quality dataCare quality metricsHealth care systemText notesText matchingClinical textHealth cohortVisit notesCare systemHealth AdministrationNatural language processing modelsMeasure documentationBag-of-wordsConvolutional neural networkOutcome measuresQuality improvementCareRule-based methodClinical notesA deep learning analysis for dual healthcare system users and risk of opioid use disorder
Yin Y, Workman E, Ma P, Cheng Y, Shao Y, Goulet J, Sandbrink F, Brandt C, Spevak C, Kean J, Becker W, Libin A, Shara N, Sheriff H, Butler J, Agrawal R, Kupersmith J, Zeng-Trietler Q. A deep learning analysis for dual healthcare system users and risk of opioid use disorder. Scientific Reports 2025, 15: 3648. PMID: 39881142, PMCID: PMC11779826, DOI: 10.1038/s41598-024-77602-4.Peer-Reviewed Original ResearchAltmetricMeSH Keywords and ConceptsConceptsRisk of opioid use disorderOpioid use disorderDeep neural networksUse disorderClinical factorsIncreased risk of opioid use disorderOpioid use disorder riskOpioid prescribing guidelinesNatural language processing of clinical notesDeep neural network modelU.S. veteransSubstance useOpioid useNatural language processingRetrospective studyBaltimore VA Medical CenterVA Medical CenterIncreased riskPrescribing guidelinesDrug useRisk factorsOpioidMedical CenterVeteransVeterans Health AdministrationLGBTQ+ status and sex of record in Veterans with post-traumatic stress disorder: demographics, comorbidities, and outpatient encounters
Workman T, Goulet J, Brandt C, Skanderson M, O’Leary J, Gordon K, Treitler-Zeng Q. LGBTQ+ status and sex of record in Veterans with post-traumatic stress disorder: demographics, comorbidities, and outpatient encounters. Frontiers In Public Health 2025, 12: 1487866. PMID: 39835315, PMCID: PMC11743380, DOI: 10.3389/fpubh.2024.1487866.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsMilitary sexual traumaLGBTQ+ individualsMedical care usagePost-traumatic stress disorderTransgenderSexual traumaMarital statusSubstance use disorder diagnosisMental healthStress disorderContext of post-traumatic stress disorderQueerLGBTQ+CrimeVeterans with post-traumatic stress disorderMaltreatmentVeteransOutpatient encountersPolicySexStatusIncreased riskDemographicsChi-squareDisorder diagnosis
2024
Prevalent Atherosclerotic Cardiovascular Disease Among Veterans by Sexual Orientation
Streed C, Duncan M, Heier K, Workman T, Beach L, Caceres B, O'Leary J, Skanderson M, Goulet J. Prevalent Atherosclerotic Cardiovascular Disease Among Veterans by Sexual Orientation. Journal Of The American Heart Association 2024, 13: e036898. PMID: 39508159, PMCID: PMC11681393, DOI: 10.1161/jaha.124.036898.Peer-Reviewed Original ResearchCitationsAltmetricConceptsPrevalent atherosclerotic cardiovascular diseasesAtherosclerotic cardiovascular diseaseIndex dateCardiovascular diseaseVeterans Health Administration dataPoor cardiovascular healthHealth administrative dataPrimary care appointmentsLGB veteransCardiovascular risk factorsCare appointmentsLogistic regression analysisSexual orientationCardiovascular healthVeteran populationHispanic ethnicityAdministrative dataNationwide cohortVeteransBaseline dateNatural language processing algorithmsSubstance useRisk factorsRegression analysisLanguage processing algorithmsGuideline concordant opioid therapy in Veterans receiving VA and community care
Ma P, Cheng Y, Goulet J, Sandbrink F, Brandt C, Spevak C, Kean J, Becker W, Libin A, Shara N, Sheriff H, Houston J, Butler J, Workman E, Agrawal R, Kupersmith J, Zeng-Treitler Q. Guideline concordant opioid therapy in Veterans receiving VA and community care. BMC Health Services Research 2024, 24: 1284. PMID: 39456008, PMCID: PMC11515256, DOI: 10.1186/s12913-024-11742-1.Peer-Reviewed Original ResearchMeSH Keywords and ConceptsConceptsDual-system usersGuideline concordant careConcordant careVA servicesCommunity careElectronic health record dataHealth record dataRates of guideline concordanceVA Medical CenterOpioid therapyAdherence to specific guidelinesBaltimore VA Medical CenterGuideline adherenceGuideline concordanceAdherence ratesGuideline recommendationsRecord dataCareDemographic factorsMedical CenterVeteransComorbid conditionsOpioid crisisUrine drug screensSpecific guidelinesImpact of complementary health approaches on opioid prescriptions among veterans with musculoskeletal disorders – A retrospective cohort study
Han L, Goulet J, Skanderson M, Redd D, Brandt C, Zeng-Treitler Q. Impact of complementary health approaches on opioid prescriptions among veterans with musculoskeletal disorders – A retrospective cohort study. Journal Of Pain 2024, 26: 104695. PMID: 39384145, PMCID: PMC11781976, DOI: 10.1016/j.jpain.2024.104695.Peer-Reviewed Original ResearchCitationsAltmetricConceptsIntegrative health approachesHealth approachOpioid prescriptionsMusculoskeletal disordersAdministration electronic health recordComplementary health approachesPrimary care visitsElectronic health recordsPharmacy dispensing recordsCIH approachesCare visitsDispensed opioid prescriptionsHealth recordsRetrospective cohort studyDispensing recordsPatient's painAnalytic sampleIndex diagnosisExposure groupCohort studyVeteransOpioid initiationQuasi-experimental investigationCIHPrescriptionThe association of pain screening and pain level with suicide among US veterans with comorbid musculoskeletal and bipolar disorder diagnoses
Abel E, Travaglini L, Snow J, Goulet J. The association of pain screening and pain level with suicide among US veterans with comorbid musculoskeletal and bipolar disorder diagnoses. Journal Of Affective Disorders 2024, 369: 429-435. PMID: 39389110, DOI: 10.1016/j.jad.2024.10.028.Peer-Reviewed Original ResearchAltmetricConceptsVeterans Health AdministrationBipolar disorder diagnosisPain screeningPain severity ratingsMusculoskeletal disordersSuicide mortalityPain severityRelative risk of suicideDisorder diagnosisVHA databaseMusculoskeletal disorder diagnosisSuicide riskActual medication useAssociation of painSuicide prevention effortsRisk of suicideHighest suicide ratesHigher suicide riskSuicide risk factorsRetrospective cohort studySubstance use disordersHealth AdministrationPain diagnosisPoisson regressionUS veteransIntimate Partner Violence Among Lesbian, Gay, and Bisexual Veterans
Warren A, Relyea M, Gross G, Eleazer J, Goulet J, Brandt C, Haskell S, Portnoy G. Intimate Partner Violence Among Lesbian, Gay, and Bisexual Veterans. Psychological Services 2024, 21: 621-625. PMID: 37602982, PMCID: PMC10879444, DOI: 10.1037/ser0000797.Peer-Reviewed Original ResearchCitationsAltmetric
Academic Achievements & Community Involvement
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Activities
activity VA Clinical Science Research and Development
2019 - PresentProfessional OrganizationsCommittee Memberactivity VA Clinical Science Research and Development
2019 - PresentPeer Review Groups and Grant Study SectionsCo-Ad Hoc Revieweractivity Medical Research Council (UK)
2019 - PresentPeer Review Groups and Grant Study SectionsRevieweractivity VA Health Services Research and Development-VISN1 CDA
2012 - PresentPeer Review Groups and Grant Study SectionsRevieweractivity VA Health Services Research and Development Centers of Innovation (COIN)
2012 - PresentPeer Review Groups and Grant Study SectionsReviewer
Honors
honor Superior Performance Award
09/01/2018, 09/01/2017, 09/01/2016, 09/01/2015, 09/01/2014, 09/01/2013, 09/01/2012, 09/01/1992, 09/01/1991, 09/01/1990National AwardDepartment of Veterans AffairsDetailsUnited Stateshonor Best Student Poster
07/01/2003National AwardAmerican Public Health Association, Mental Health SectionDetailsUnited Stateshonor Urban Health Initiative Award
07/01/1998Other AwardPew Charitable TrustDetailsUnited States
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Yale University
950 Campbell Ave, Bldg 35a
West Haven, CT 06516
United States