Jeffrey M Vinocur, MD
Associate Professor of PediatricsCards
About
Research
Publications
2024
Cardiac phenotype in adolescents and young adults with long-chain 3-hydroxyacyl CoA dehydrogenase (LCHAD) deficiency
Elizondo G, Saini A, Gonzalez de Alba C, Gregor A, Harding C, Gillingham M, Vinocur J. Cardiac phenotype in adolescents and young adults with long-chain 3-hydroxyacyl CoA dehydrogenase (LCHAD) deficiency. Genetics In Medicine 2024, 26: 101123. PMID: 38501492, DOI: 10.1016/j.gim.2024.101123.Peer-Reviewed Original ResearchLong-chain 3-hydroxyacyl-CoA dehydrogenase deficiencyLong-chain 3-hydroxyacyl-CoA dehydrogenaseCardiac involvementCardiac arrestMetabolic decompensationCardiac phenotypeDilated cardiomyopathyLong-chain 3-hydroxyacyl-CoA dehydrogenase deficient patientsEpisodes of metabolic decompensationEnd-stage dilated cardiomyopathyOut-of-hospital cardiac arrestAcute cardiac decompensationIn-hospital cardiac arrestFatty acid oxidation disordersLife-threatening arrhythmiasInfantile dilated cardiomyopathySudden cardiac arrestPotential risk factorsCardiac manifestationsCardiac decompensationRestrictive cardiomyopathyRecurrent episodesRetrospective cohortRisk stratificationPeripheral neuropathyReduced kinase function in two ultra‐rare TNNI3K variants in families with congenital junctional ectopic tachycardia
Pham C, Koopmann T, Vinocur J, Blom N, Silbiger V, Mittal K, Bootsma M, Palm K, Clur S, Barge‐Schaapveld D, Hamilton R, Lodder E. Reduced kinase function in two ultra‐rare TNNI3K variants in families with congenital junctional ectopic tachycardia. Clinical Genetics 2024, 106: 37-46. PMID: 38424693, DOI: 10.1111/cge.14504.Peer-Reviewed Original ResearchCongenital junctional ectopic tachycardiaJunctional ectopic tachycardiaK variantEctopic tachycardiaDilated cardiomyopathySupraventricular tachycardiaReduction of kinase activityAssociated with dilated cardiomyopathyFour-generation familyAtrioventricular (AV) nodeInteracting kinasesMissense variantsKinase functionTroponin I-interacting kinaseKinase activityTNNI3KGenetic penetranceTNNI3Variant carriersMultigenerational familiesGenetic testingTroponin ICardiac arrhythmiasTachycardiaVariantsDoubly unusual in double discordance: Appendage-based accessory pathway in congenitally corrected transposition
Beach C, Vinocur J. Doubly unusual in double discordance: Appendage-based accessory pathway in congenitally corrected transposition. HeartRhythm Case Reports 2024, 10: 180-181. PMID: 38496739, PMCID: PMC10943534, DOI: 10.1016/j.hrcr.2023.12.018.Peer-Reviewed Original Research
2023
Lyme Carditis in the Pediatric Population
Beach C, Vinocur J. Lyme Carditis in the Pediatric Population. 2023, 111-119. DOI: 10.1007/978-3-031-41169-4_11.Peer-Reviewed Original ResearchHigh-grade AV blockTemporary transvenous pacingPediatricPediatric patientsLyme carditisHemodynamic instabilityAntibiotic therapyPediatric populationPR prolongationTransvenous pacingAV blockCommon manifestationConduction abnormalitiesTimely administrationCarditisFull recoveryPatientsDiseaseGreat majorityAccompanying increaseTherapyPacingAbnormalitiesSuspicionAdministrationProlongationClinical presentation of calmodulin mutations: the International Calmodulinopathy Registry
Crotti L, Spazzolini C, Nyegaard M, Overgaard M, Kotta M, Dagradi F, Sala L, Aiba T, Ayers M, Baban A, Barc J, Beach C, Behr E, Bos J, Cerrone M, Covi P, Cuneo B, Denjoy I, Donner B, Elbert A, Eliasson H, Etheridge S, Fukuyama M, Girolami F, Hamilton R, Horie M, Iascone M, Jiménez-Jaimez J, Jensen H, Kannankeril P, Kaski J, Makita N, Muñoz-Esparza C, Odland H, Ohno S, Papagiannis J, Porretta A, Prandstetter C, Probst V, Robyns T, Rosenthal E, Rosés-Noguer F, Sekarski N, Singh A, Spentzou G, Stute F, Tfelt-Hansen J, Till J, Tobert K, Vinocur J, Webster G, Wilde A, Wolf C, Ackerman M, Schwartz P. Clinical presentation of calmodulin mutations: the International Calmodulinopathy Registry. European Heart Journal 2023, 44: 3357-3370. PMID: 37528649, PMCID: PMC10499544, DOI: 10.1093/eurheartj/ehad418.Peer-Reviewed Original ResearchConceptsClinical presentationPrimary neurological manifestationsCardiac structural abnormalitiesLife-threatening arrhythmia syndromesArrhythmic event rateAbsence of symptomsLife-threatening arrhythmiasSodium channel blockersCongenital heart defectsAntiadrenergic interventionsCardiac eventsHeart failureNeurological manifestationsUnderlying molecular mechanismsDefinitive recommendationsClinical severityChannel blockersObservational studySudden deathIndex caseArrhythmia syndromesHeart defectsPrevalent phenotypeStructural abnormalitiesCurrent managementTranslation of Tools and Techniques from the Adult Electrophysiology World to Pediatric Cardiac Implantable Electronic Devices
Howard T, Vinocur J. Translation of Tools and Techniques from the Adult Electrophysiology World to Pediatric Cardiac Implantable Electronic Devices. Cardiac Electrophysiology Clinics 2023, 15: 515-525. PMID: 37865524, DOI: 10.1016/j.ccep.2023.06.004.Peer-Reviewed Original ResearchWolff-Parkinson-White (WPW) Syndrome
Vinocur J. Wolff-Parkinson-White (WPW) Syndrome. In Clinical Practice 2023, 103-127. DOI: 10.1007/978-3-031-41479-4_6.Peer-Reviewed Original ResearchAsymptomatic patientsRisk stratificationSudden deathCalcium channel blockersEarliest atrial activationAntidromic AVRTAsymptomatic WPWOrthodromic AVRTPharmacologic therapyUncommon manifestationCatheter ablationVariety of manifestationsAtrial fibrillationPathway conductionWolff-ParkinsonAccessory pathwaySerious manifestationsVentricular pacingBidirectional accessory pathwaysCatheter stabilityWhite syndromeAtrial activationFirst lesionPatientsWPW
2022
Life-threatening cardiac arrhythmia and sudden death during electronic gaming: An international case series and systematic review
Lawley C, Tester M, Sanatani S, Prendiville T, Beach C, Vinocur J, Horie M, Uhm J, Khongphatthanayothin A, Ayers M, Starling L, Yoshida Y, Shah M, Skinner J, Turner C. Life-threatening cardiac arrhythmia and sudden death during electronic gaming: An international case series and systematic review. Heart Rhythm 2022, 19: 1826-1833. PMID: 37850595, DOI: 10.1016/j.hrthm.2022.08.003.Peer-Reviewed Original ResearchConceptsInternational case seriesLife-threatening cardiac arrhythmiasCardiac arrhythmiasCase seriesSystematic reviewCatecholaminergic polymorphic ventricular tachycardiaPolymorphic ventricular tachycardiaLong QT syndromeLethal cardiac arrhythmiasCardiac eventsCoronary ischemiaCardiac surgeryVentricular arrhythmiasCardiac arrestSusceptible childrenVentricular tachycardiaVentricular fibrillationSudden deathCardiac conditionsArrhythmic triggersCardiac diagnosisPatientsQT syndromeSusceptible individualsArrhythmiasAblation of ventricular ectopy in complex congenital heart disease: The best of both worlds
Vinocur JM. Ablation of ventricular ectopy in complex congenital heart disease: The best of both worlds. HeartRhythm Case Reports 2022, 8: 548. PMID: 35996706, PMCID: PMC9391403, DOI: 10.1016/j.hrcr.2022.05.021.Commentaries, Editorials and LettersAn unusual cause of repolarization abnormality after congenital heart surgery: A case report
Barresi NV, Marcus BS, Beach CM, Vinocur JM. An unusual cause of repolarization abnormality after congenital heart surgery: A case report. Journal Of Electrocardiology 2022, 72: 91-94. PMID: 35395484, DOI: 10.1016/j.jelectrocard.2022.03.007.Peer-Reviewed Case Reports and Technical Notes
Academic Achievements & Community Involvement
Clinical Care
Overview
Clinical Specialties
Pediatrics; Pediatric Cardiology; Electrophysiology
Fact Sheets
Adult Congenital Heart Disease
Learn More on Yale MedicinePediatric Congenital Heart Surgery
Learn More on Yale MedicineHeart Arrhythmia
Learn More on Yale MedicineAnesthesia for Atrial Fibrillation
Learn More on Yale Medicine
Board Certifications
Adult Congenital Heart Disease
- Certification Organization
- AB of Internal Medicine
- Original Certification Date
- 2019
Pediatric Cardiology
- Certification Organization
- AB of Pediatrics
- Original Certification Date
- 2014
Pediatrics
- Certification Organization
- AB of Pediatrics
- Original Certification Date
- 2011