Jie Li
Financial Analyst 3Cards
About
Research
Publications
2026
Age-dependent association of uric acid levels with depressive symptoms in adults: NHANES 2007–2018
Yao C, Luo G, Zhang M, Fu Y, Liu X, Li Z, Chen Z, Li J. Age-dependent association of uric acid levels with depressive symptoms in adults: NHANES 2007–2018. Journal Of Neural Transmission 2026, 1-11. PMID: 42313172, DOI: 10.1007/s00702-026-03197-x.Peer-Reviewed Original ResearchNational Health and Nutrition Examination SurveyHigher uric acid levelsDepressive symptomsUric acid levelsAge-dependent associationOdds ratioLogistic regression modelsSerum uric acid levelsOdds of depressive symptomsHealth and Nutrition Examination SurveyWeighted multivariable logistic regression modelsAssociated with lower oddsAssociated with higher oddsNutrition Examination SurveyMultivariate logistic regression modelRegression modelsMultinomial logistic regression modelAssociation of uric acid levelAcid levelsNo significant associationExamination SurveyUric acid groupLower oddsHigher oddsGames-Howell testEnergy metabolism dysregulation in schizophrenia with non-thyroidal illness syndrome: Roles of citric acid and Tyrosol-4-sulfate
Chen J, Dong Y, Li Y, Liu N, Wang X, Han Y, Li Y, Guo Y, Li S, Li J. Energy metabolism dysregulation in schizophrenia with non-thyroidal illness syndrome: Roles of citric acid and Tyrosol-4-sulfate. Schizophrenia Research 2026, 295: 179-186. PMID: 42284951, DOI: 10.1016/j.schres.2026.06.007.Peer-Reviewed Original ResearchNon-thyroidal illness syndromeIllness syndromeDifferential metabolitesMetabolic phenotypeReceiver operating characteristic curve analysisUntargeted metabolomic profilingCharacteristic curve analysisUltra-high-performance liquid chromatography high-resolution mass spectrometryHormonal criteriaThyroid dysfunctionMetabolomic profilesClinical symptomsSchizophrenia patientsEndocrine disturbancesMetabolic dysregulationPositive symptomsCurve analysisNon-thyroidEnergy metabolism dysregulationPsychotic symptomsSchizophreniaEnrichment analysisLiquid chromatography high-resolution mass spectrometrySymptomsMetabolic indicatorsAssociation between serum non-enzymatic antioxidants and cognitive impairment in drug-naïve patients with schizophrenia
Feng Z, Qiu Y, Wang Y, Li M, Sun X, Su Q, Xuekelaiti Z, Wang S, Xu Y, Zhang Y, Li J. Association between serum non-enzymatic antioxidants and cognitive impairment in drug-naïve patients with schizophrenia. BMC Psychiatry 2026 PMID: 42271292, DOI: 10.1186/s12888-026-08177-9.Peer-Reviewed Original ResearchDrug-naive patientsPositive and Negative Syndrome ScaleMATRICS Consensus Cognitive BatteryOverall cognitive performanceCognitive performanceHealthy controlsAssociated with verbal learningLevels of HDL-CConsensus Cognitive BatteryNegative Syndrome ScaleHDL-CAssociated with lower oddsMethodsSerum levelsSyndrome ScaleSerum levelsCognitive batteryVerbal learningSZ patientsSZ groupCognitive domainsPsychiatric disordersSerum level of HDL-CPsychiatric symptomsSchizophreniaCognitive functionLongitudinal associations between stress, packaged snack consumption, chronic fatigue and emotional symptoms in adolescents: a structural mediation model
Zhang C, Tian X, Li M, Liu Y, Gao Y, Li J. Longitudinal associations between stress, packaged snack consumption, chronic fatigue and emotional symptoms in adolescents: a structural mediation model. Psychology Health & Medicine 2026, ahead-of-print: 1-23. PMID: 42233767, DOI: 10.1080/13548506.2026.2680606.Peer-Reviewed Original ResearchDaily Life Stressors ScaleEmotional symptomsLongitudinal associationsChronic fatigueStructural mediation modelAssociation of stressSnack consumptionHealth-related behavior changeStructural equation modelingMediation modelEmotional difficultiesHeightened stressMaturity ScaleBehavioral changesBrain cohortAdolescentsEquation modelingStress managementPubertal statusStressor ScaleModel fitHealthy dietary behaviorsSymptomsExploratory subgroup analysisSexual Maturation ScaleAssociations between plasma BDNF, VEGF, and EGF and cognition in drug-naïve schizophrenia with and without sleep disturbances
Zhou B, Su Q, Wang Z, Huo Y, Wang S, Feng Z, Xu Y, Qiu Y, Li J. Associations between plasma BDNF, VEGF, and EGF and cognition in drug-naïve schizophrenia with and without sleep disturbances. European Archives Of Psychiatry And Clinical Neuroscience 2026, 1-12. PMID: 42215707, DOI: 10.1007/s00406-026-02283-1.Peer-Reviewed Original ResearchPlasma brain-derived neurotrophic factorBrain-derived neurotrophic factorMATRICS Consensus Cognitive BatteryCognitive impairmentSevere cognitive impairmentSleep disturbancePittsburgh Sleep Quality IndexAssociated with better cognitive performanceConsensus Cognitive BatteryDrug-naive schizophreniaTianjin Anding HospitalMultiple cognitive domainsDisturbance groupSleep-related measuresDrug-naive patientsCognitive batteryVerbal learningCore symptomsCognitive domainsVascular endothelial growth factorCognitive performanceSchizophreniaBackgroundCognitive impairmentVisual learningSleep Quality IndexImpact of severe anxiety, depression, and their comorbidity on glucose metabolism in first-episode antipsychotic-naïve schizophrenia patients
Lu C, Han Y, Wang L, Sun W, Li Y, Liu N, Li S, Li J, Zhang X. Impact of severe anxiety, depression, and their comorbidity on glucose metabolism in first-episode antipsychotic-naïve schizophrenia patients. Journal Of Neural Transmission 2026, 1-12. PMID: 42189202, DOI: 10.1007/s00702-026-03175-3.Peer-Reviewed Original ResearchPositive and Negative Syndrome ScaleHamilton Anxiety ScaleSevere depressionSevere anxietyNegative Syndrome ScaleHamilton Depression ScaleGlucose metabolism parametersHealthy controlsAssociated with SASyndrome ScaleSchizophrenia patientsSZ patientsHAMD-24Psychiatric symptomsInsulin resistanceIllness onsetAnxiety ScaleMetabolic parametersDepression ScaleGlucose metabolismAnxietyDepressionSchizophreniaIncidence of SAMetabolic monitoringSex-specific associations between serum uric acid, psychopathology, and cognition in deficit schizophrenia
Li Y, Lu C, Zhang J, Yue K, Li Y, Liu N, Wang X, Zhang X, Xu G, Li S, Li J. Sex-specific associations between serum uric acid, psychopathology, and cognition in deficit schizophrenia. Schizophrenia Research 2026, 294: 176-184. PMID: 42116246, DOI: 10.1016/j.schres.2026.05.003.Peer-Reviewed Original ResearchConceptsNon-deficit schizophreniaDeficit schizophreniaAssociated with more severe positive symptomsPositive and Negative Syndrome ScaleAssessment of Neuropsychological StatusNegative Syndrome ScalePersistent negative symptomsSevere positive symptomsRBANS total scoreSex-specific associationsAssociated with symptomsHigher UA levelsNegative symptomsPositive symptomsSyndrome ScaleRepeatable BatteryCognitive profileDelayed memoryNeuropsychological StatusSerum UAEffects of sexTotal scorePsychopathologySex differencesSchizophreniaStatic and dynamic alterations of local brain activity in schizophrenia and associations with clinical symptoms and cognitive function
Wang S, Ren P, Lu C, Zhang X, Dong Y, Liu F, Li S, Li J. Static and dynamic alterations of local brain activity in schizophrenia and associations with clinical symptoms and cognitive function. Progress In Neuro-Psychopharmacology And Biological Psychiatry 2026, 147: 111724. PMID: 42044686, DOI: 10.1016/j.pnpbp.2026.111724.Peer-Reviewed Original ResearchConceptsTemporal poleSchizophrenia patientsCognitive deficitsBrain activityFractional amplitudeAssociated with negative symptomsResting-state functional magnetic resonance imaging dataAssociated with verbal learningFractional amplitude of low-frequency fluctuationAmplitude of low-frequency fluctuationFunctional magnetic resonance imaging dataSpecific symptom dimensionsMiddle temporal regionsStatic brain activityMiddle temporal gyrusLocalized brain dysfunctionSuperior frontal gyrusLocal brain activityDynamic regional homogeneityMagnetic resonance imaging dataLow-frequency fluctuationsGeneral psychopathologyNegative symptomsSymptom dimensionsLocal neural activityA cross-sectional study on the impact of early systematic antidepressant therapy on positive/negative affect and impulsivity in euthymic bipolar disorder patients
Han D, Cui P, Wang M, Hou X, Yang C, Li J. A cross-sectional study on the impact of early systematic antidepressant therapy on positive/negative affect and impulsivity in euthymic bipolar disorder patients. PLOS ONE 2026, 21: e0346872. PMID: 42018588, PMCID: PMC13102236, DOI: 10.1371/journal.pone.0346872.Peer-Reviewed Original ResearchConceptsAntidepressant treatmentNegative affectMotor impulsivityBipolar disorderPositive/negative affectAntidepressant useMediation analysisPositive and Negative Affect ScaleEuthymic bipolar disorder patientsLevels of negative affectPeriods of euthymiaBarratt Impulsiveness ScaleNon-planning impulsivityBipolar disorder patientsTreated with antidepressantsNegative Affect ScaleAttentional impulsivityElevated impulsivityImpulsiveness ScaleAntidepressant therapyBipolar euthymiaDepressive episodeBipolar patientsPositive affectDisorder patientsEffect of transcranial alternating current stimulation on auditory verbal hallucinations in patients with treatment-resistant schizophrenia
Gao Y, Yan H, Hu R, Liu S, Wang X, Chu L, Jia Q, Li S, Li M, Li J. Effect of transcranial alternating current stimulation on auditory verbal hallucinations in patients with treatment-resistant schizophrenia. Schizophrenia Research 2026, 293: 72-80. PMID: 41946278, DOI: 10.1016/j.schres.2026.03.025.Peer-Reviewed Original ResearchConceptsAuditory verbal hallucinationsTreatment-resistant schizophreniaDorsolateral prefrontal cortexTemporo-parietal junctionLeft dorsolateral prefrontal cortexPSYRATS-AHTranscranial alternating current stimulationVerbal hallucinationsLeft temporo-parietal junctionEfficacy of transcranial alternating current stimulationPsychotic Symptom Rating ScalesEffects of transcranial alternating current stimulationStable antipsychotic medicationAuditory Hallucinations subscaleRepeated-measures analysisSymptom Rating ScaleCurrent stimulationWeek 6Antipsychotic medicationHallucination subscalePrefrontal cortexFollow-up phaseSchizophreniaRating ScaleTreatment phase