Jie Li
Financial Analyst 2, YSM FinanceCards
About
Research
Publications
2026
Temporal interference stimulation (TIS) for major depressive disorder: right lingual gyrus as a predictor
Zhang C, Yang Y, Wang C, Wang L, Sun W, Mu C, Feng Z, Liu N, Guan X, Lu Y, Li S, Zhang C, Li J. Temporal interference stimulation (TIS) for major depressive disorder: right lingual gyrus as a predictor. Journal Of Affective Disorders 2026, 405: 121660. PMID: 41871633, DOI: 10.1016/j.jad.2026.121660.Peer-Reviewed Original ResearchAmplitude of low-frequency fluctuationMajor depressive disorderRight lingual gyrusHDRS-17Depressive disorderLingual gyrusTemporal interference stimulationHamilton Depression Rating ScaleMajor depressive disorder patientsDepression Rating ScaleResting-state functional MRITianjin Anding HospitalPredictors of treatment responseTreatment responseLow-frequency fluctuationsPredictive valueRight amygdalaDepressive symptomsBaseline amplitudeInterference stimulationFunctional MRIROC analysisRs-fMRIRating ScaleDeep brain targetsCognitive function differences across subtypes of first-episode antipsychotic-naïve schizophrenia: insights from event-related potentials
Lu C, Li S, Zhang X, Han Y, Wang L, Sun W, Zhang C, Wang S, Li S, Li J, Zhang X. Cognitive function differences across subtypes of first-episode antipsychotic-naïve schizophrenia: insights from event-related potentials. European Archives Of Psychiatry And Clinical Neuroscience 2026, 1-12. PMID: 41863586, DOI: 10.1007/s00406-026-02221-1.Peer-Reviewed Original ResearchEvent-related potentialsCognitive functionNegative symptomsPsychiatric symptomsPositive and Negative Syndrome ScaleN100 componentThree-stimulus auditory oddball paradigmNegative Syndrome ScaleSevere psychiatric symptomsCognitive function differencesAuditory oddball paradigmLatencies of N100Syndrome ScaleSZ subtypesElectrophysiological markersSensitive electrophysiological markerOddball paradigmCognitive impairmentPartial correlation analysisSymptom dominancePSD groupN100P3bP3aNSDCytokines and cognitive function in first-episode drug-naïve MDD: an inflammation panel perspective
Dong Y, Zhang C, Zhang B, Tian X, Gao Y, Li M, Li J. Cytokines and cognitive function in first-episode drug-naïve MDD: an inflammation panel perspective. Journal Of Neural Transmission 2026, 1-9. PMID: 41801436, DOI: 10.1007/s00702-026-03133-z.Peer-Reviewed Original ResearchMajor depressive disorderMajor depressive disorder patientsFirst-episode drug-naive MDD patientsDrug-naive MDD patientsCognitive functionMDD patientsTAS-20Healthy controlsHamilton Depression Rating Scale-17Cognitive impairmentScores of TAS-20Assessment of Neuropsychological StatusSocial cognitive functioningProcess of cognitive impairmentToronto Alexithymia ScaleRepeatable BatteryDepressive disorderHAMD-17Alexithymia ScaleAnxiety symptomsNeuropsychological StatusPsychiatric disordersCognitive performanceHAMA-14HC groupUnveiling the Protective Mechanism of Ufmylation Against Heart Failure
Tandra V, Ayala J, Gazik M, Li H, Su H, Li J. Unveiling the Protective Mechanism of Ufmylation Against Heart Failure. Journal Of Molecular And Cellular Cardiology Plus 2026, 15: 100570. DOI: 10.1016/j.jmccpl.2025.100570.Peer-Reviewed Original ResearchNeural vulnerability to stress in adolescents: a longitudinal study using polyconnectomic scoring of depression risk
Liu Y, Li M, Chen C, Wang S, Gao Y, Jing Y, Zhou Y, Xie M, Zhang C, Liu Z, Zhang B, Li J. Neural vulnerability to stress in adolescents: a longitudinal study using polyconnectomic scoring of depression risk. BMC Medicine 2026, 24: 184. PMID: 41731553, DOI: 10.1186/s12916-026-04704-3.Peer-Reviewed Original ResearchConceptsClinically diagnosed depressive disorderDepressive symptomsDepressive disorderNeural vulnerabilityPerceived stressEmotional correlatesSensitive period of brain developmentLarge-scale functional connectivity patternsPeriod of brain developmentAssociated with depressive symptomsAssociated with lower performanceMultiple cognitive domainsSensitive periodVulnerability to stressFunctional connectivity patternsAssociated with anxietyFollow-up anxietyAssociated with greater variabilityCorrelates of stressCognitive domainsCognitive functionEmotional symptomsCognitive outcomesEmotional outcomesDepression riskDiagnosis-specific associations of plasma NGAL in drug-naïve schizophrenia and major depressive disorder: an exploratory cross-sectional study
Zhou B, Sun X, Wang X, Zhang X, Su Q, Wang S, Wang J, Feng Z, Xu Y, Zhang Y, Li J. Diagnosis-specific associations of plasma NGAL in drug-naïve schizophrenia and major depressive disorder: an exploratory cross-sectional study. BMC Psychiatry 2026, 26: 266. PMID: 41721300, PMCID: PMC13032228, DOI: 10.1186/s12888-026-07909-1.Peer-Reviewed Original ResearchMajor depressive disorderDepressive disorderNeutrophil Gelatinase-Associated LipocalinPlasma neutrophil gelatinase-associated lipocalinDrug-naive schizophreniaDrug-naive patientsGeneral psychopathologyCore symptomsCognitive domainsCognitive performanceCognitive associationsDiagnostic groupsSCZNGAL levelsFDR correctionLongitudinal studyPartial correlationPlasma NGAL levelsPersistent inflammatory activityExploratory cross-sectional studyDisordersDiagnostic discriminationCompensatory neuroprotective mechanismCross-sectional studyPartial Pearson correlationsAtherosclerosis risk and clinical correlates in first-episode drug-naïve patients with major depressive disorder: a large-scale cross-sectional study
Jin X, Lu C, Zhou N, Han Y, Li Y, Liu N, Wang X, Li S, Li J, Zhang X. Atherosclerosis risk and clinical correlates in first-episode drug-naïve patients with major depressive disorder: a large-scale cross-sectional study. Journal Of Neural Transmission 2026, 1-10. PMID: 41711825, DOI: 10.1007/s00702-026-03122-2.Peer-Reviewed Original ResearchMajor depressive disorderHamilton Depression Rating ScaleFEDN MDD patientsLow-density lipoprotein cholesterolDepressive disorderPositive and Negative Syndrome ScaleFirst-episode drug-naive patientsRating ScaleAtherogenic coefficientMajor depressive disorder patientsHamilton Anxiety Rating ScaleNegative Syndrome ScalePositive subscale scoresAS riskDepression Rating ScaleAnxiety Rating ScaleAssociated with HAMD scoreCross-sectional studyDrug-naive patientsFasting venous blood samplesLow-density lipoprotein cholesterol levelsPositive symptomsSyndrome ScalePositive subscaleDepression severityEfficacy and safety of toludesvenlafaxine hydrochloride sustained-release tablets in depression with ineffective or partially effective initial antidepressant treatment: a single-arm, multicenter clinical study
Yang J, Jia Y, Chen K, Liang W, Long J, Li M, Wei Q, Wang J, Yan B, Li K, Li J, Yang F. Efficacy and safety of toludesvenlafaxine hydrochloride sustained-release tablets in depression with ineffective or partially effective initial antidepressant treatment: a single-arm, multicenter clinical study. Frontiers In Psychiatry 2026, 16: 1740789. PMID: 41727401, PMCID: PMC12917316, DOI: 10.3389/fpsyt.2025.1740789.Peer-Reviewed Original ResearchDimensional Anhedonia Rating ScaleHamilton Anxiety ScaleQ-LES-Q-SFClinical Global ImpressionAntidepressant treatmentWeeks of treatmentMADRS scoreClinical Global Impression of Severity scaleQuality of Life Enjoyment and Satisfaction QuestionnaireRating ScaleEnjoyment and Satisfaction QuestionnaireBaseline to 8 weeksDepression Rating ScaleTriple reuptake inhibitorsSexual dysfunctionCGI-S scoresAntidepressant therapyReuptake inhibitorsAnxiety ScaleClinical efficacyAntidepressantsOutcome measuresDepressionSeverity ScaleShort formIntramuscular Generic Injection (QLG2072) versus Haloperidol in Chinese Patients with Acute Agitation: A Phase 3 Multicenter, Randomized, Double-Blind, Active-Controlled Trial
Dong F, Wang Z, Li C, Li X, Zhu D, Li J, Wang Z, Gong J, Zhou J, Liu H, Zhang Y, Zhang X, Chen X, Yu M, Tan X, Qian M, Luo Y, Guo W, Xie S, Huang J, Zhao J, Wan J, Shan Y, Li N, Wang J, Ju Y, Wang J, Bian Q, Wang G. Intramuscular Generic Injection (QLG2072) versus Haloperidol in Chinese Patients with Acute Agitation: A Phase 3 Multicenter, Randomized, Double-Blind, Active-Controlled Trial. Drug Design Development And Therapy 2026, 20: 561494. PMID: 41778148, PMCID: PMC12951296, DOI: 10.2147/dddt.s561494.Peer-Reviewed Original ResearchConceptsPositive and Negative Syndrome Scale-Excited ComponentIM haloperidolAcute agitationPositive and Negative Syndrome Scale-Excited Component scoreClinical Global Impression-Improvement scoreIncidence of extrapyramidal symptomsDouble-blindIncidence of treatment-emergent adverse eventsTreatment-emergent adverse eventsOlanzapine injectionExtrapyramidal symptomsPrimary endpointPsychiatric populationsChinese patientsHaloperidolBetween-group differencesEfficacy measuresNeurological tolerancePhase 3 trialActive-controlled trialPost-injectionPhase 3 multicenterOlanzapineBetween-groupBaseline to 2Emotion regulation mediates the effect of insomnia on non-suicidal self-injury in adolescents: the moderating role of mindfulness
Li S, Sun W, Han Y, Wang L, Sun X, Zhou Z, Li J, Zhang X. Emotion regulation mediates the effect of insomnia on non-suicidal self-injury in adolescents: the moderating role of mindfulness. Journal Of Neural Transmission 2026, 1-10. PMID: 41619019, DOI: 10.1007/s00702-026-03111-5.Peer-Reviewed Original ResearchNon-Suicidal Self-InjuryLevels of mindfulnessEmotion regulationInsomnia Severity IndexSelf-injuryStructural equation modelingAssociated with non-suicidal self-injuryModerating effect of mindfulnessEmotion regulation difficultiesEmotion Regulation ScaleEffects of mindfulnessPast-yearAttention Awareness ScaleModerating RoleModerating effectEffects of insomniaIndirect effectsEmotion dysregulationRegulation difficultiesLow mindfulnessNSSI behaviorsRegulation ScaleInsomnia severityAwareness ScalePsychological mechanisms