Voluntary Faculty
Voluntary faculty are typically clinicians or others who are employed outside of the School but make significant contributions to department programs at the medical center or at affiliate institutions.
Voluntary rank detailsHyun Jung Kim, MD
Clinical InstructorAbout
Research
Publications
2026
Glycine-modulating Slc6a20a-ASO restores NMDA receptor function in SHANK2 and SHANK3-mutant mice and cortical organoids
Roh J, Bae M, Oh Y, Yang Y, Lee S, Hwang W, Yang E, Kim H, Jang H, Choi H, Kim H, Kim J, Kim E. Glycine-modulating Slc6a20a-ASO restores NMDA receptor function in SHANK2 and SHANK3-mutant mice and cortical organoids. Nature Communications 2026 PMID: 42215483, DOI: 10.1038/s41467-026-73881-9.Peer-Reviewed Original ResearchTherapeutic efficacy of nimodipine and topiramate on migraine and vestibular migraine; A prospective multicenter open-label study
Choi S, Oh S, Kim H, Park J, Choi J, Oh E, Choi J, Jeong S, Lee S, Kim J, Kim S, Kim H, Choi K, Kim J. Therapeutic efficacy of nimodipine and topiramate on migraine and vestibular migraine; A prospective multicenter open-label study. PLOS ONE 2026, 21: e0344948. PMID: 41855149, PMCID: PMC13001945, DOI: 10.1371/journal.pone.0344948.Peer-Reviewed Original ResearchConceptsMigraine Disability Assessment ScaleHeadache Impact Test-6Open-label studyVestibular migraineInter-group differencesHeadache daysTherapeutic efficacyReferral-based university hospitalL-type calcium channel blockerHeadache Impact Test-6 scoresMulticenter open-label studyTherapeutic effectTherapeutic effect of nimodipinePain rating scaleEffect of nimodipineCalcium channel blockersEfficacy of nimodipineDizziness Handicap InventoryDisability Assessment ScaleStudy discontinuationTopiramate groupAssociated with improvementsChannel blockersFavorable tolerabilityTherapeutic optionsIntellectual disability and structural defects of the CaV2.1 channel in episodic ataxia type 2: correlation using an AI prediction model
Kim H, Lee J, Lee S, Kim S, Kim J. Intellectual disability and structural defects of the CaV2.1 channel in episodic ataxia type 2: correlation using an AI prediction model. Journal Of Neurology 2026, 273: 181. PMID: 41781521, PMCID: PMC12960376, DOI: 10.1007/s00415-026-13731-2.Peer-Reviewed Original ResearchConceptsIntellectual functioningIntellectual indicesCognitive impairmentVerbal Comprehension IndexWorking Memory IndexFull-scale IQPerceptual Reasoning IndexTM-scoreMemory indexIntellectual disabilityReasoning IndexMolecular basisWild-typeGenotype to phenotypeProtein lengthVariant proteinsProtein modelsPathogenic variantsImpairmentP/Q-type calcium channelsEpisodic ataxia type 2CaV2.1 channelsComprehensive indexProteinDiverse clinical presentationsEndoscopic resection versus surgery for T1 rectal cancer: A systematic review and meta-analysis of oncologic and safety outcomes
Moon Y, Hong Y, Kim H, Park S, Ryu H, Kwak J, Lee S, Kim J. Endoscopic resection versus surgery for T1 rectal cancer: A systematic review and meta-analysis of oncologic and safety outcomes. Surgical Endoscopy 2026, 1-10. PMID: 41772228, DOI: 10.1007/s00464-026-12674-z.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsT1 rectal cancerDisease-free survivalEndoscopic resectionRectal cancerOverall survivalCertainty of evidencePostoperative complicationsAdverse eventsLong-term oncologic outcomesHigh riskRisk of delayed bleedingIncidence of postoperative complicationsImpaired qualityNon-randomized observational studySafety of ERMinimally invasive alternativeMeta-analysisHigher risk of deathMinor adverse eventsImpaired quality of lifeSystematic reviewROBINS-I toolRisk of deathOncological outcomesRisk of biasTransforming unstructured breast cancer pathology reports into the Observational Medical Outcomes Partnership Common Data Model
Kim B, Song W, Yoon E, Kim S, Lee H, Kim J, Suh K, Kim K, Park S, Kim E, Kim S, Yoon S, Yoo S. Transforming unstructured breast cancer pathology reports into the Observational Medical Outcomes Partnership Common Data Model. BMC Medical Informatics And Decision Making 2026 PMID: 41764468, DOI: 10.1186/s12911-026-03375-7.Peer-Reviewed Original ResearchObservational Medical Outcomes PartnershipCommon data modelOMOP CDMObservational Medical Outcomes Partnership Common Data ModelTertiary general hospitalNatural language processingCancer pathology reportsAll-Cause MortalityBreast cancer pathology reportsBreast cancer pathologyPathology reportsGeneral HospitalClinical research dataBreast cancerPathological dataData modelOncology researchReceiver operating characteristic curveOperating characteristics curveBreastFeasibility studyOpen-source toolInitial pathologic diagnosisLanguage processingCancer researchThe Korean Rectal Cancer Multidisciplinary Committee Clinical Practice Guidelines for Rectal Cancer version 2.0
Ryu H, Kim H, Kang D, Kwak Y, Kwak H, Kwon Y, Kim D, Kim B, Kim J, Kim J, Kim J, Kim T, Kim H, Nam S, Noh G, Bong J, Sung N, Shin S, Lee K, Lee S, Lee S, Lee J, Lee J, Ihn M, Lim J, Ji W, Pyo D, Hong Y, Kwak J, Committee O. The Korean Rectal Cancer Multidisciplinary Committee Clinical Practice Guidelines for Rectal Cancer version 2.0. Annals Of Coloproctology 2026, 42: 4-33. PMID: 41802304, PMCID: PMC12971177, DOI: 10.3393/ac.2025.01396.0199.Peer-Reviewed Original ResearchClinical practice guidelinesCancer VersionPractice guidelinesEvidence-based clinical practice guidelinesNational health insurance systemRectal cancer outcomesLevel of evidenceHealth insurance systemEvidence synthesisPatient valuesHealthcare contextCancer outcomesSystemic treatmentRectal cancerRecommendation developmentConsensus guidelinesMultidisciplinary collaborationGuideline versionSurgical techniqueColorectal cancerClinical practiceClinical concernDiagnostic imagingInsurance systemGuidelinesAssociations Among Probable REM-sleep Behavior Disorder, Dopamine Transporter Binding, and Cognitive Performance in Parkinson Disease
Kim H, Qi Y, Goldberg T, Lee S. Associations Among Probable REM-sleep Behavior Disorder, Dopamine Transporter Binding, and Cognitive Performance in Parkinson Disease. Alzheimer Disease & Associated Disorders 2026, 40: 1-7. PMID: 41665290, DOI: 10.1097/wad.0000000000000717.Peer-Reviewed Original ResearchConceptsREM sleep behavior disorderDopamine transporter bindingTransporter bindingCognitive performanceBehavioral disordersStriatal dopamine transporter bindingSymbol Digit Modalities TestDopamine transporter activityREM Sleep Behavior Disorder Screening QuestionnairePositive screenParkinson's diseaseCognitive controlNeurobiological mechanismsStriatal dopamineDopamine transporterNeuropsychological testsCognitive changesDopamineREM sleepModal testingPRBDNo significant interactionScreening QuestionnaireSDMTProdromal marker of Parkinson's diseaseImpact of estrogen receptor expression levels on chemo-responsiveness and prognosis of breast cancer patients treated with neoadjuvant chemotherapy
Bai K, Sung H, Chung Y, Shin H, Kim E, Suh K, Kim S, Kim J, Kwon H, Park S. Impact of estrogen receptor expression levels on chemo-responsiveness and prognosis of breast cancer patients treated with neoadjuvant chemotherapy. Npj Breast Cancer 2026, 12: 37. PMID: 41634050, PMCID: PMC12976317, DOI: 10.1038/s41523-026-00907-2.Peer-Reviewed Original ResearchPositive breast cancerER-negative tumorsPatients treated with neoadjuvant chemotherapyER-lowER expression levelsNeoadjuvant chemotherapyER-negativePositive tumorsBreast cancerClinicopathological characteristicsChemo-responseClinical outcomesEstrogen receptorBreast cancer patients treated with neoadjuvant chemotherapyER-negative breast cancerResponse to NACEstrogen receptor expression levelPre-NAC biopsyProgesterone receptor-positiveResponse to chemotherapyExpression levelsReceptor expression levelsPre-NACResidual diseaseReceptor-positiveAssociations between Smoking, Opioid Analgesic Use, and Risk For Chemical Coping in Korean Patients with Advanced Cancer
Jung E, Kim Y, Dev R, Suh K, Kim J, Kim S, Kim J, Lee K, Kim J, Lee J, Bruera E. Associations between Smoking, Opioid Analgesic Use, and Risk For Chemical Coping in Korean Patients with Advanced Cancer. Cancer Research And Treatment 2026 PMID: 41643565, DOI: 10.4143/crt.2025.1034.Peer-Reviewed Original ResearchMorphine equivalent daily dosePhysicians assess riskChemical copingEdmonton Symptom Assessment SystemKorean patientsAdvanced cancerOpioid useNever-smokersFormer smokersCurrent smokersHigh dosesHigh doses of opioidsSmoking statusDoses of opioidsHeavy coffee drinkersNon-medical opioid useOpioid analgesic useEquivalent daily dosePain scoresAnalgesic useCoping strategiesDaily doseProspective studyCoffee drinkersCoffee usePostoperative Radiotherapy May Improve Survival in Certain Patients with pN2 Non-Small Cell Lung Cancer Who Do Not Have Extranodal Extension
Jeon S, Song C, Jeon J, Chung J, Cho S, Kim K, Jheon S, Kim S, Kim Y, Kim J. Postoperative Radiotherapy May Improve Survival in Certain Patients with pN2 Non-Small Cell Lung Cancer Who Do Not Have Extranodal Extension. Cancer Research And Treatment 2026 PMID: 41643567, DOI: 10.4143/crt.2025.644.Peer-Reviewed Original ResearchNon-small cell lung cancerPN2 non-small cell lung cancerPostoperative radiotherapyExtranodal extensionCell lung cancerPropensity score matchingLymphatic invasionLung cancerTherapeutic efficacySubgroup analysisEfficacy of postoperative radiotherapyPositive N2 lymph nodesLimitations of retrospective designDisease-free survivalN2 lymph nodesScore matchingSubgroup of patientsPairs of patientsPathologic N2Nodal burdenSurgical resectionOverall survivalAdjuvant chemotherapyClinical parametersNo significant difference