Gauri Panse, MBBS, MD
she/her/hers
Associate Professor of Dermatology and PathologyCards
About
Research
Publications
2026
Granular Cell Dermatofibroma Demonstrates Loss‐of‐Function Mutations in V‐ATPase Component Genes
Jiang X, Hu R, Choate K, Panse G. Granular Cell Dermatofibroma Demonstrates Loss‐of‐Function Mutations in V‐ATPase Component Genes. Journal Of Cutaneous Pathology 2026 PMID: 42108978, DOI: 10.1111/cup.70134.Peer-Reviewed Original ResearchGranular cell tumorComponent genesV-ATPaseHistopathological variantsCell dermatofibromaMalignant granular cell tumorAggressive surgical managementLoss-of-function mutationsVariant of dermatofibromaAbundant granular cytoplasmLoss-of-functionAssociated with mutationsPaired control tissuesV-ATPase mutationsCell tumorsSurgical managementExome sequencingMolecular alterationsGranular cytoplasmMolecular findingsGenetic mutationsControl tissuesMutationsGenesDermatofibromaIdentification of NTRK3 fusions in plaque‐like CD34‐positive dermal fibroma
Cloutier J, Lee M, Yeh I, Jour G, Panse G. Identification of NTRK3 fusions in plaque‐like CD34‐positive dermal fibroma. Histopathology 2026, 88: 1443-1450. PMID: 41755369, DOI: 10.1111/his.70120.Peer-Reviewed Original ResearchPlaque-like CD34-positive dermal fibromaSpindle cell tumorsCell tumorsNTRK3 fusionsDermal fibromaProliferation of bland spindle cellsMedallion-like dermal dendrocyte hamartomaAreas of active investigationDiffuse CD34 expressionSpindle cell lesionsRNA-based next-generation sequencingClinical follow-upBland spindle cellsGene fusionsSpectrum of lesionsNTRK3 gene fusionsOncogenic gene fusionsIndolent behaviorTyrosine kinase domainCD34 expressionClinicopathological featuresDermatofibrosarcoma protuberansSpindle cellsHistopathological criteriaCell lesionsEpithelioid Fibrous Histiocytoma Involving Deep Dermis and Subcutaneous Adipose Tissue
Dileep A, Cowper S, Panse G. Epithelioid Fibrous Histiocytoma Involving Deep Dermis and Subcutaneous Adipose Tissue. Journal Of Cutaneous Pathology 2026 PMID: 41692006, DOI: 10.1111/cup.70071.Peer-Reviewed Original ResearchEpithelioid fibrous histiocytomaALK immunohistochemistryHistopathological variantsFibrous histiocytomaMorphologic spectrumClinical follow-up periodDeep dermisEvidence of recurrenceAdipose tissueFollow-up periodALK immunoreactivitySubcutaneous adipose tissueMorphologic mimicsEosinophilic cytoplasmSubcutaneous involvementVesicular nucleiEpithelioid cellsNuclear labelingALKSuperficial dermisEpidermal collarettesHistiocytomaImmunohistochemistryDermisResponse to: Comment on "Isolated perineal plaque as the initial presentation of pemphigus vulgaris"
Workineh A, Panse G, Tomayko M, Little A. Response to: Comment on "Isolated perineal plaque as the initial presentation of pemphigus vulgaris". JAAD Case Reports 2026 DOI: 10.1016/j.jdcr.2026.02.036.Commentaries, Editorials and LettersGRHL-rearranged sebaceoma: expanding the clinical and morphologic spectrum
Dileep A, Ko C, LeBlanc R, Panse G, Cloutier J. GRHL-rearranged sebaceoma: expanding the clinical and morphologic spectrum. Human Pathology 2026, 170: 106058. PMID: 41580204, DOI: 10.1016/j.humpath.2026.106058.Peer-Reviewed Original ResearchConceptsMismatch repair (MMR)-deficient tumorsNext-generation sequencingClinicopathological spectrumRNA-based next-generation sequencingMorphologic spectrumMolecular featuresHead and neckDistinct groupsMolecularly distinct groupsBenign sebaceous neoplasmsGene alterationsNo recurrenceCombined cohortBasaloid proliferationsCystic growthTumorInfundibulocystic structuresSebaceomaSebaceous neoplasmsBasaloid nestsUse of TRBC1 Immunohistochemistry in the Diagnosis of Hypopigmented Mycosis Fungoides
Zhao J, Panse G, Ko C. Use of TRBC1 Immunohistochemistry in the Diagnosis of Hypopigmented Mycosis Fungoides. Journal Of Cutaneous Pathology 2026 PMID: 41506259, DOI: 10.1111/cup.70053.Peer-Reviewed Original Research
2025
Epithelioid Fibrous Histiocytoma With Abundant Multinucleated Giant Cells: Report of 3 Cases of an Unusual Variant With Predilection for Acral Sites
Wang S, Zubek A, Panse G. Epithelioid Fibrous Histiocytoma With Abundant Multinucleated Giant Cells: Report of 3 Cases of an Unusual Variant With Predilection for Acral Sites. American Journal Of Dermatopathology 2025, 47: 909-916. PMID: 41263920, DOI: 10.1097/dad.0000000000002937.Peer-Reviewed Original ResearchConceptsEpithelioid fibrous histiocytomaAnaplastic lymphoma kinaseMultinucleated giant cellsFibrous histiocytomaHistopathological spectrumGiant cellsAcral sitesAnaplastic lymphoma kinase positivityPresence of ALK rearrangementCases of epithelioid fibrous histiocytomaClinical follow-upBenign cutaneous neoplasmsWell-circumscribed lesionAbundant eosinophilic cytoplasmBenign fibrous histiocytomaAbundant multinucleated giant cellsSheets of epithelioid cellsYears of ageALK rearrangementEpithelioid neoplasmNo recurrenceCase seriesCutaneous neoplasmsEosinophilic cytoplasmFibrous stromaCutaneous Extracavitary Primary Effusion Lymphoma: A Case Report and Review of Literature
Dileep A, Zaki T, Leasure A, Xu M, Nelson C, Panse G. Cutaneous Extracavitary Primary Effusion Lymphoma: A Case Report and Review of Literature. Journal Of Cutaneous Pathology 2025, 53: 163-168. PMID: 41218762, DOI: 10.1111/cup.70007.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsExtracavitary primary effusion lymphomaPrimary effusion lymphomaHuman herpesvirus 8Primary cutaneous manifestationBody cavity effusionsHistopathological featuresUnusual caseCavity effusionsElevated EBV viral loadsEBV viral loadB-cell lymphomaHistory of feverPleomorphic lymphoid cellsUnusual immunophenotypeImmunocompromised patientsAtypical cellsProgressive dyspneaCD138+CD3+CD45+Viral loadISH positivityDiagnostic pitfallsCase reportLymphoid cellsIsolated perineal plaque as the initial presentation of pemphigus vulgaris
Workineh A, Panse G, Tomayko M, Little A. Isolated perineal plaque as the initial presentation of pemphigus vulgaris. JAAD Case Reports 2025, 67: 158-161. PMID: 41446696, PMCID: PMC12723278, DOI: 10.1016/j.jdcr.2025.10.034.Peer-Reviewed Original ResearchHybrid granular cell tumor/perineurioma: a report of two rare cases with PIK3CA mutations
Toklu A, Panse G, Jour G, Linos K, Cloutier J, Dehner C. Hybrid granular cell tumor/perineurioma: a report of two rare cases with PIK3CA mutations. Virchows Archiv 2025, 487: 597-604. PMID: 40159563, DOI: 10.1007/s00428-025-04089-3.Peer-Reviewed Original ResearchPeripheral nerve sheath tumorsHybrid peripheral nerve sheath tumorsRare mesenchymal neoplasmNerve sheath tumorsWell-circumscribed lesionGLUT1 stainingPIK3CA mutationsUnusual neoplasmsSheath tumorsMesenchymal neoplasmsRare caseDual differentiationDifferential diagnosisPathological spectrumMolecular testingGranular cell componentPathogenic mutationsTumorPerineurial cellsPIK3CANeoplasmsPerineuriomaMolecular featuresGranular cellsMolecular analysis
Clinical Care
Overview
Gauri Panse, MD, is a dermatopathologist who specializes in diagnosing diseases of the skin, hair, and nails through microscopic evaluation. Dr. Panse examines tissue samples to identify a range of conditions, including inflammatory disorders, autoimmune issues, and skin growths.
As an assistant professor of dermatology at Yale School of Medicine, Dr. Panse focuses on improving diagnostic approaches to both skin and soft tissue diseases. She frequently lectures at national meetings of dermatology, pathology, and dermatopathology societies, and has published extensively on these topics.
Dr. Panse received her medical training from Topiwala National Medical College and Bai Yamunabai Laxman Nair Charitable Hospital in India. She completed a residency in pathology at Baystate Medical Center, Tufts University, followed by a fellowship in bone and soft tissue pathology at M.D. Anderson Cancer Center and a fellowship in dermatopathology at Yale School of Medicine.
Clinical Specialties
Dermatopathology
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Laboratory for Medicine and Pediatrics (LMP)
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15 York Street, Fl 5th, Rm 5031
New Haven, CT 06510
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