Adjunct Faculty
Adjunct faculty typically have an academic or research appointment at another institution and contribute or collaborate with one or more School of Medicine faculty members or programs.
Adjunct rank detailsCarolina Maciel, MD
About
Research
Publications
2026
Do Neuroprognostic Studies in Comatose Cardiac Arrest Survivors Report Factors Contributing to Self-fulfilling Prophecy Bias in Their Methodology? A Systematic Review (P1-19.005)
Khaliq A, Forero D, Gibatova V, Pollini V, Ahmad B, Hernandez S, Frota L, Comparan H, Busl K, Maciel C. Do Neuroprognostic Studies in Comatose Cardiac Arrest Survivors Report Factors Contributing to Self-fulfilling Prophecy Bias in Their Methodology? A Systematic Review (P1-19.005). Neurology 2026, 106 DOI: 10.1212/wnl.0000000000215973.Peer-Reviewed Original ResearchLiver transplantation for valproic acid-induced acute liver failure in POLG mutation-related mitochondrial disease with cardiac and neurological involvement
Mehta R, Santos A, Shukla A, Belal A, Ibrahim H, Alquadan K, Leghrouz M, Lord S, Vrakas G, Shahmohammadi A, Wokhlu A, Assarzadegan N, Bruzzone M, Maciel C, Bhatia P, Sabat S, Boothe M, Mehta R, Owoyemi I, Pruinelli L, Beduschi T. Liver transplantation for valproic acid-induced acute liver failure in POLG mutation-related mitochondrial disease with cardiac and neurological involvement. Journal Of Liver Transplantation 2026, 22: 100342. DOI: 10.1016/j.liver.2026.100342.Peer-Reviewed Original Researchataxia neuropathy spectrumPOLG-related disordersAlpers-Huttenlocher syndromeprogressive external ophthalmoplegiacatalytic subunitmyocerebrohepatopathy spectrumcatalytic subunit of mitochondrial DNA polymerase gammamitochondrial DNA polymerase gammaDNA polymerase gammacellular energy productionmtDNA maintenancemtDNA replicationmitochondrial DNApolymerase gammamtDNA depletionnuclear DNAmtDNAmitochondrial diseasePOLG genemitochondrial hepatopathyPOLG mutationsoxidative phosphorylationintracellular organellespathogenic variantsadenosine triphosphateUnveiling Reporting & Representation of Race and Ethnicity in Acute Interventional Neurology Trials: A Systematic Review
Comparan H, Augustin B, Frota L, Mathelier M, Khaliq A, Pomar-Forero D, Ahmad B, Alcala-Arana R, Edwards M, Maciel C, Busl K. Unveiling Reporting & Representation of Race and Ethnicity in Acute Interventional Neurology Trials: A Systematic Review. Equity Neuroscience 2026, 2: 100041. DOI: 10.1016/j.neuros.2026.100041.Peer-Reviewed Original Researchacute ischemic strokesubarachnoid hemorrhageneurology trialsintracerebral hemorrhageblack patientssystematic reviewpatients 7ethnicity reportingNative Hawaiian/Other Pacific Islanderfull-text articlesHispanic patientshemorrhagepatientsischemic strokedisease burdenincidence patternsblack representationtrialsethnic minorities
2025
Practice Patterns and Trends in Temperature Control After Cardiac Arrest: A Multi-Specialty Survey
Carr C, Eckert M, Bhakta N, Guirgis F, Hopson C, Maciel C, Becker T. Practice Patterns and Trends in Temperature Control After Cardiac Arrest: A Multi-Specialty Survey. Journal Of Clinical Medicine 2025, 14: 8592. PMID: 41375895, PMCID: PMC12693480, DOI: 10.3390/jcm14238592.Peer-Reviewed Original Researchpost-cardiac arrest carecardiac arrestpractice patternsResults:</b>attending-level physiciansEmergency Medicine Societypost-cardiac arrest managementweb-based surveytargeted temperature managementlocal practice environmentcommunity cliniciansphysicians' knowledgephysician specialtyarrest etiologypractice environmentcritical careMethods:</b>TTM2-trialpractice variabilitypilot testintensive care medicineinstitutional protocolMedicine Societycarecare medicineEarly Markers of Systemic Inflammation are not Related to Pain Burden After Aneurysmal Subarachnoid Hemorrhage: A Multicenter Observational Study
Kardon A, Ren H, Gerard E, Pomar-Forero D, Pop R, Ahmad B, Ciryam P, Parikh G, Badjatia N, Maciel C, Busl K, Chen C, Morris N. Early Markers of Systemic Inflammation are not Related to Pain Burden After Aneurysmal Subarachnoid Hemorrhage: A Multicenter Observational Study. Neurocritical Care 2025, 44: 518-526. PMID: 41125902, DOI: 10.1007/s12028-025-02396-w.Peer-Reviewed Original Researchintensive care unitchronic opioid useaneurysmal subarachnoid hemorrhagepain burdenmulticenter observational studysubarachnoid hemorrhagepain scoresopioid useopioid-sparing pain management strategysensitivity analysis restricted to patientsobservational studymarkers of systemic inflammationICU courseanalysis restricted to patientsearly markerseffective analgesic treatmentHunt-Hess scoresubgroup of patientsblood inflammatory biomarkerspain management strategiesblood-brain barrier breakdownrestricted to patientsinflammatory blood biomarkersrefractory headacheabortion managementCOMPRESSIVE DATA STORAGE FOR LONG-TERM EEG: VALIDATION BY VISUAL ANALYSIS
Kalamangalam G, Venkatesan S, Bruzzone M, Wang Y, Maciel C, Mitropanopoulos S, Cibula J, Patel K, Babajani-Feremi A. COMPRESSIVE DATA STORAGE FOR LONG-TERM EEG: VALIDATION BY VISUAL ANALYSIS. Clinical Neurophysiology Practice 2025, 10: 331-339. PMID: 40809319, PMCID: PMC12344260, DOI: 10.1016/j.cnp.2025.07.005.Peer-Reviewed Original Researchdiscrete cosine transformsingular value decompositioncompression ratiodata analytics pipelinemassive data volumesdata analytics techniqueslong-term EEG monitoringcosine transformlatent spacedata sizedata compressiondata volumebiomedical datadata storagedimension reductionvalue decompositioncompressed dataSVD componentsvisual analysishigh-variabilityrun lengthoriginal recordsdatasetEEGBest Practices for Hospital-Based Donor Care Unit Operations Part 2
Vail E, Goyal V, McGinity A, Sarge T, Heimbach J, Mielke A, Tompeck A, Maciel C, Busl K, Leventhal T, Sanghavi D, Kumar R, Sommer P, Olthoff K, Martin N, Windham S, Bakhru R. Best Practices for Hospital-Based Donor Care Unit Operations Part 2. CHEST Critical Care 2025, 3: 100144. DOI: 10.1016/j.chstcc.2025.100144.Commentaries, Editorials and LettersSubarachnoid Haemorrhage
Busl K, Akkus S, Maciel C. Subarachnoid Haemorrhage. 2025, 225-242. DOI: 10.1093/med/9780198864714.003.0017.Chapterssubarachnoid haemorrhagedegree of neurological impairmentdelayed cerebral ischaemiaculprit aneurysmrescue therapyearly complicationsprompt diagnosissystemic complicationscardiac dysfunctionsevere headachesurgical clippingrespiratory compromiseendovascular interventioncerebral ischaemiaday 4improve outcomesneurological impairmentinfluence outcomesneuroprotective agentscomplicationspatientsvariable degreeshæmorrhagetreatmentoutcomes
2024
Prolonged Monitoring of Brain Electrical Activity in the Intensive Care Unit
Carneiro T, Goswami S, Smith C, Giraldez M, Maciel C. Prolonged Monitoring of Brain Electrical Activity in the Intensive Care Unit. Neurologic Clinics 2024, 43: 31-50. PMID: 39547740, DOI: 10.1016/j.ncl.2024.08.001.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsEarly vigabatrin to augment GABAergic pathways in post-anoxic status epilepticus
Maciel C, Ahmad B, Jose Bruzzone Giraldez M, Eisenschenk S, Ramsay E, Maranchick N, Peloquin C, Hirsch L, Busl K. Early vigabatrin to augment GABAergic pathways in post-anoxic status epilepticus. Epilepsy & Behavior 2024, 160: 110082. PMID: 39393141, DOI: 10.1016/j.yebeh.2024.110082.Peer-Reviewed Original Researchstatus epilepticusgamma-aminobutyric acidGABAergic pathwayhypoxic-ischemic brain injurypost-cardiac arrest periodhypoxic-ischemic insultoutcomes of patientseffective adjunctive therapyinhibition of gamma-aminobutyric acidLondon-Innsbruck Colloquiumadjunctive therapyacute seizureseffective therapypoor outcomeepilepticusexclusion criteriaearly inhibitionsynergistic augmentationgamma-aminobutyric acid catabolismarrest periodtherapeutic nihilismseizuresclinal trialsallosteric modulatorsvigabatrin