Aydin Arici, MD
Professor of Obstetrics, Gynecology, and Reproductive SciencesCards
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Obstetrics, Gynecology & Reproductive Sciences
PO Box 208063
New Haven, CT 06520-8063
United States
About
Titles
Professor of Obstetrics, Gynecology, and Reproductive Sciences
Biography
Aydin Arici, MD, is Professor of Obstetrics, Gynecology and Reproductive Sciences. His clinical interests include IVF, infertility, endometriosis, implantation, myomas, and uterine anomalies. Dr. Arici is a board certified specialist in Obstetrics and Gynecology and in Reproductive Endocrinology.
Dr. Arici received his medical degree from Istanbul Medical School in Turkey, and completed a residency in Obstetrics and Gynecology at Columbia University, College of Physicians and Surgeons, in New York City. His postgraduate training also included a fellowship in Reproductive Endocrinology and Infertility at the University of Texas Southwestern Medical Center in Dallas. He served as Director of Reproductive Endocrinology and Infertility at the Yale University School of Medicine for seven years.
Dr. Arici has been the recipient of many National Institutes of Health and pharmaceutical industry-sponsored research grants. More than 300 articles by Dr Arici have been published in leading journals. He is the Senior Editor of the book titled ‘Non-invasive Management of Gynecologic Disorders’, and he is the Series Editor of the Gynecology in Practice series.
Appointments
Obstetrics, Gynecology & Reproductive Sciences
ProfessorPrimary
Other Departments & Organizations
- Fertility Center
- Fertility Preservation Program
- In Vitro Fertilization Program
- Obstetrics, Gynecology & Reproductive Sciences
- Perimenopausal & Menopausal Therapy Program
- Pituitary Program
- Recurrent Pregnancy Loss Program
- Reproductive Endocrinology & Infertility
- Reproductive Physiology Group
- Third-Party Reproductive Program
- WHRY Pilot Project Program Investigators
- Women's Health Research at Yale
- Yale Medicine
- Yale Ventures
Education & Training
- Residency
- Columbia University-Harlem Hospital (2015)
- Fellowship
- University of Texas-SW Medical Center (1992)
- MD
- Istanbul University (1979)
Research
Overview
Medical Research Interests
ORCID
0000-0003-2183-2175
Research at a Glance
Yale Co-Authors
Publications Timeline
Research Interests
Mert Ozan Bahtiyar, MD
Murat Basar, PhD
Harvey Kliman, MD, PhD
Joshua Copel, MD
Endometriosis
Cytokines
Chemokines
Reproductive Techniques
Infertility
Publications
2019
Long‐term GnRH agonist therapy before in vitro fertilization (IVF) for improving fertility outcomes in women with endometriosis
Jaafar S, Sallam H, Arici A, Garcia‐Velasco J, Abou‐Setta A. Long‐term GnRH agonist therapy before in vitro fertilization (IVF) for improving fertility outcomes in women with endometriosis. 2019, 2019 PMCID: PMC6353287, DOI: 10.1002/14651858.cd013240.Peer-Reviewed Original Research
2018
EndoART: A proposed randomized controlled trial on endometriomas in assisted reproductive technologies, comparing the effect of no intervention, surgery, and prolonged GnRH downregulation on pregnancy rates
Tomassetti C, Adamson D, Arici A, Canis M, Hompes P, Hummelshoj L, Mol B, Nardo L, Rombauts L, D’Hooghe T. EndoART: A proposed randomized controlled trial on endometriomas in assisted reproductive technologies, comparing the effect of no intervention, surgery, and prolonged GnRH downregulation on pregnancy rates. Journal Of Endometriosis And Pelvic Pain Disorders 2018, 10: 158-173. DOI: 10.1177/2284026518784236.Peer-Reviewed Original ResearchConceptsClinical pregnancy rateLive birth ratePregnancy rateART pregnancy rateFresh ART cyclesOvarian surgeryART cyclesOutcome measuresCumulative clinical pregnancy rateSecondary outcome measuresPrimary outcome measureMulti-center trialReproductive technologiesHigher pregnancy rateBirth rateQuality of lifeDifferent treatment groupsPelvic painOvarian reserveHormonal suppressionClinical managementTreatment groupsMatter of debateSurgeryGnRHTumor necrosis factor alfa and interleukin 1 alfa induced phosphorylation and degradation of inhibitory kappa B alpha are regulated by estradiol in endometrial cells
Arlıer S, Kayışlı Ü, Arıcı A. Tumor necrosis factor alfa and interleukin 1 alfa induced phosphorylation and degradation of inhibitory kappa B alpha are regulated by estradiol in endometrial cells. Journal Of Turkish Society Of Obstetric And Gynecology 2018, 15: 50-59. PMID: 29662717, PMCID: PMC5894537, DOI: 10.4274/tjod.47700.Peer-Reviewed Original ResearchConceptsEndometrial cellsNormal endometriumEctopic endometriumInhibitory kappa B-alphaTranscription factor nuclear factor kappa BInhibitory kappa B (IκBα) proteinMonocyte chemoattractant protein-1Ectopic endometrial cellsHomologous eutopic endometriumNuclear factor kappa BCultured endometrial cellsEffects of estradiolNecrosis factor alfaChemoattractant protein-1Human endometrial cellsRegulation of chemokinesTumor necrosis factorFactor kappa BKappa B alphaUterine endometrial cellsEutopic endometriumInflammatory responseNecrosis factorEndometriumKappa B
2012
High rate of allergies among women with endometriosis
Matalliotakis I, Cakmak H, Matalliotakis M, Kappou D, Arici A. High rate of allergies among women with endometriosis. Journal Of Obstetrics And Gynaecology 2012, 32: 291-293. PMID: 22369407, DOI: 10.3109/01443615.2011.644358.Peer-Reviewed Original ResearchMeSH Keywords and ConceptsConceptsAllergic rhinitisFamily historyYale University HospitalPerennial allergic rhinitisAutoimmune inflammatory diseaseStage of endometriosisPrevalence of allergyMain outcome measuresPositive family historyEndometriosis stageAllergic diseasesAutoimmune disordersMedical filesUniversity HospitalInflammatory diseasesPositive historyOutcome measuresEndometriosisAllergyControl groupAsthmaOverall riskWomenRhinitisMedications18 Women's Health
Rackow B, Arici A, Martin V, Reid R, Lewis J, Borgen P, Herndon E, Harnisch D, Silasi D, Azodi M, Olive D, Williams S, Burd I, Scheib S, Boyle K, Rose P, Bagley A, Trent M, Freeman E, Aeby T, Dantas S, Davidson S, Hudak C. 18 Women's Health. 2012, 981-1028. DOI: 10.1016/b978-1-4557-0738-6.00018-8.Peer-Reviewed Original ResearchCitations
2011
Endoplasmic reticulum (ER) homeostasis is cycle-dependent and the inflammatory cytokines TNF-α and ILI-1β induce er stress by regulating BIP expression in human endometrial ENDOTHELIAL CELLS
Ocak N, Guzel E, Bozkurt I, Bagriyanik A, Arici A, Kayisli U. Endoplasmic reticulum (ER) homeostasis is cycle-dependent and the inflammatory cytokines TNF-α and ILI-1β induce er stress by regulating BIP expression in human endometrial ENDOTHELIAL CELLS. Fertility And Sterility 2011, 96: s27. DOI: 10.1016/j.fertnstert.2011.07.110.Peer-Reviewed Original ResearchCitationsEndoplasmic reticulum homeostasis is crucial for in vitro blastocyst development
Bozkurt I, Basar M, Tekmen I, Arici A, Kayisli U. Endoplasmic reticulum homeostasis is crucial for in vitro blastocyst development. Fertility And Sterility 2011, 96: s80. DOI: 10.1016/j.fertnstert.2011.07.310.Peer-Reviewed Original ResearchImplantation Rate Remains Unaffected in Women with Endometriosis Compared to Tubal Factor Infertility
Matalliotakis I, Sakkas D, Illuzzi J, Matalliotaki C, Arici A. Implantation Rate Remains Unaffected in Women with Endometriosis Compared to Tubal Factor Infertility. Journal Of Endometriosis And Pelvic Pain Disorders 2011, 3: 86-92. DOI: 10.5301/je.2011.8528.Peer-Reviewed Original ResearchCitationsConceptsTubal factor infertilityMale infertilityTubal infertilityInfertility groupEndometriosis groupFactor infertilityImplantation rateAge-matched control groupMale infertility groupTubal infertility groupICSI treatment cyclesReduced pregnancy rateMethods Five hundredDelivery rateNumber of embryosConsecutive IVFIVF treatmentIVF programPregnancy rateUterine receptivityEndometriosisTreatment cyclesControl groupInfertilityPatientsEndometriosis: Pathogenesis and Management of Pain
Kulp J, Arici A. Endometriosis: Pathogenesis and Management of Pain. 2011, 40-49. DOI: 10.1002/9781444391855.ch4.Peer-Reviewed Original ResearchCitationsConceptsNonsteroidal anti-inflammatory medicationsGonadotropin-releasing hormone agonistAnti-inflammatory medicationsChronic pelvic painDysfunctional immune responseManagement of painOral contraceptive pillsSymptoms of endometriosisTime of laparoscopyEtiology of endometriosisSymptomatic endometriomasPelvic painSurgical treatmentHormone agonistMedical managementRetrograde menstruationContraceptive pillsLikely multifactorialImmune responseCommon conditionEndometriosisGenetic predispositionPainStem cellsPopulation of lesions
2010
Effect of the new legislation and single-embryo transfer policy in Turkey on assisted reproduction outcomes: preliminary results
Kutlu P, Atvar O, Vanlioglu O, Kutlu U, Arici A, Yilmaz S, Yilmaz E, Delikara N, Bener F, Kamar A, Alpak O, Ozekici U. Effect of the new legislation and single-embryo transfer policy in Turkey on assisted reproduction outcomes: preliminary results. Reproductive BioMedicine Online 2010, 22: 208-214. PMID: 21195669, DOI: 10.1016/j.rbmo.2010.10.007.Peer-Reviewed Original ResearchMeSH Keywords and ConceptsConceptsMultiple pregnancy ratePregnancy rateAge groupsSingle embryo transfer policyOverall populationClinical pregnancy rateSecond treatment cycleAssisted reproduction outcomesYears of ageNumber of embryosDifferent age groupsClinical pregnancyMulticentre studyMultiple pregnanciesReproduction treatmentTreatment cyclesReproduction outcomesOlder agePregnancyOutcomesFurther investigationSignificant declineFurther cyclesAgeGroup
Clinical Trials
Current Trials
Fibroids and Unexplained Infertility Treatment with Epigallocatechin Gallate; A Natural CompounD in Green Tea (FRIEND)
HIC ID2000032075RoleSub InvestigatorPrimary Completion Date05/31/2025Recruiting ParticipantsPre-IVF Treatment With a GnRH Antagonist in Women With Endometriosis (PREGnant)
HIC ID2000027121RoleSub InvestigatorPrimary Completion Date09/30/2024Recruiting ParticipantsGenderFemaleAge18 years - 38 years
Clinical Care
Overview
Clinical Specialties
Fact Sheets
Surrogacy
Learn More on Yale MedicineIn Vitro Fertilization (IVF)
Learn More on Yale MedicinePediatric Chemotherapy
Learn More on Yale MedicinePolycystic Ovary Syndrome (PCOS)
Learn More on Yale Medicine
Board Certifications
Reproductive Endocrinology & Infertility
- Certification Organization
- AB of Obstetrics & Gynecology
- Latest Certification Date
- 2020
- Original Certification Date
- 1994
Obstetrics & Gynecology
- Certification Organization
- AB of Obstetrics & Gynecology
- Latest Certification Date
- 2020
- Original Certification Date
- 1988
Yale Medicine News
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News
- October 14, 2024
Yale Ob/Gyn Participates in Fertility Preservation Conference
- October 14, 2024
Preserving Hope: Fertility Care for Patients with Cancer and Hematological Disorders
- June 14, 2019
Over 200 Yale Medicine Physicians Make 2019 ‘Best Doctors’ List
- April 15, 2009
Non-Invasive Management of Gynecologic Disorders
Get In Touch
Contacts
Obstetrics, Gynecology & Reproductive Sciences
PO Box 208063
New Haven, CT 06520-8063
United States
Locations
Yale Obstetrics, Gynecology & Reproductive Services
Academic Office
Farnam Memorial Building
310 Cedar Street, Ste FMB 329K
New Haven, CT 06510
Patient Care Locations
Are You a Patient? View this doctor's clinical profile on the Yale Medicine website for information about the services we offer and making an appointment.