Adjunct Faculty
Adjunct faculty typically have an academic or research appointment at another institution and contribute or collaborate with one or more School of Medicine faculty members or programs.
Adjunct rank detailsDenny Sakkas, PhD
About
Research
Publications
2026
Microfluidic automation improves oocyte recovery from follicular fluid of patients undergoing in vitro fertilization
Mutlu B, Civale S, Diettrich J, Gupta N, Barber T, Sayare M, Penzias A, Alper M, Toth T, Kapur R, Toner M, Sakkas D, Ozkumur E. Microfluidic automation improves oocyte recovery from follicular fluid of patients undergoing in vitro fertilization. Nature Medicine 2026, 32: 906-914. PMID: 41680481, PMCID: PMC13004694, DOI: 10.1038/s41591-026-04207-x.Peer-Reviewed Original ResearchConceptsIn vitro fertilizationFollicular fluidOocyte recoveryIn vitro fertilization success rateFollicular fluid of patientsHigh-quality blastocystsPatient treatmentIn vitro fertilization centerFluid of patientsLive birthsTreatment optionsClinical studiesEmbryo poolsMature oocytesGlobal health challengeFF samplesOocytesClinical practicePatientsSuccess rateTreatmentHealth challengesBlastocystInfertilityReply: immature oocyte proportion may or may not compromise ICSI outcomes, but methods do: a critical appraisal
Sripada V, Sakkas D, Vaughan D, Morse B, Fouks Y. Reply: immature oocyte proportion may or may not compromise ICSI outcomes, but methods do: a critical appraisal. Human Reproduction 2026, deag013. PMID: 41653405, DOI: 10.1093/humrep/deag013.Peer-Reviewed Original ResearchThe impact of endometrial fluid on single euploid frozen embryo transfers, to cancel or not?
Patel K, Sakkas D, Morse B, Duvall D, Penzias A, Vaughan D. The impact of endometrial fluid on single euploid frozen embryo transfers, to cancel or not? Human Reproduction 2026, 41: 353-360. PMID: 41639890, DOI: 10.1093/humrep/deag010.Peer-Reviewed Original ResearchConceptsEuploid frozen embryo transferFrozen embryo transferLive birth rateFrozen embryo transfer cyclesEuploid FET cyclesEndometrial fluidCycle cancellationIncidence of EFEmbryo transferEuploid embryosEF groupFET cyclesPresence of EFLow incidenceLower live birth ratesPre-implantation genetic testingInclusion criteriaStudy funding/competing interest(sRetrospective cohort studyLogistic regression analysisSecondary analysisStatistically significant differenceTrophectoderm biopsyEndometrial pathologyCases of EF40th anniversary of Human Reproduction: reflecting on four decades of scientific excellence
Barratt C, Kirkegaard K, Sakkas D, Wise L, Williams A. 40th anniversary of Human Reproduction: reflecting on four decades of scientific excellence. Human Reproduction 2026, 41: 137-137. PMID: 41630363, DOI: 10.1093/humrep/deaf241.Peer-Reviewed Original ResearchFertility preservation in patients with medical indications: a committee opinion
Medicine P, Gracia C, Amato P, Anderson J, Flyckt R, Hansen K, Hill M, Jain T, Jindal S, Kalra S, Pier B, Sakkas D, Steiner A, Tanrikut C, Trolice M, Senapati S, Smith R, Plowden T, Yauger B, Brannigan R, Ginsburg E, Robins J, Shannon C, Goldstein J, Brooks M. Fertility preservation in patients with medical indications: a committee opinion. Fertility And Sterility 2026, 125: 247-259. PMID: 41494900, DOI: 10.1016/j.fertnstert.2025.12.001.Peer-Reviewed Original ResearchSperm Chromatin Structure Analysis and Clinical Correlations
Vaughan D, Sakkas D. Sperm Chromatin Structure Analysis and Clinical Correlations. 2026, 139-144. DOI: 10.1016/b978-0-443-21477-6.00048-1.Peer-Reviewed Original ResearchThe Preparation of Sperm
Sakkas D. The Preparation of Sperm. 2026, 196-200. DOI: 10.1016/b978-0-443-21477-6.00268-6.Peer-Reviewed Original Research
2025
FOCUSING ON PATIENTS: SIMPLIFYING OS (OVARIAN STIMULATION) WITH RECOMBINANT HUMAN FOLLICLE-STIMULATING HORMONE (R-HFSH) MONOTHERAPY IN OOCYTE DONATION
Patel K, Sakkas D, Wirka K, Collares F, Hayward B, Bortoletto P. FOCUSING ON PATIENTS: SIMPLIFYING OS (OVARIAN STIMULATION) WITH RECOMBINANT HUMAN FOLLICLE-STIMULATING HORMONE (R-HFSH) MONOTHERAPY IN OOCYTE DONATION. Fertility And Sterility 2025, 124: e35. DOI: 10.1016/j.fertnstert.2025.07.153.Peer-Reviewed Original ResearchA MULTIMODAL ATLAS OF HUMAN EMBRYOS REVEALS THE REGULATORY LOGIC OF LINEAGE SPECIFICATION FROM THE CLEAVAGE STAGE TO DAY 13
Neuhausser W, Ardestani G, Sakkas D, Habibi E. A MULTIMODAL ATLAS OF HUMAN EMBRYOS REVEALS THE REGULATORY LOGIC OF LINEAGE SPECIFICATION FROM THE CLEAVAGE STAGE TO DAY 13. Fertility And Sterility 2025, 124: e55. DOI: 10.1016/j.fertnstert.2025.07.212.Peer-Reviewed Original ResearchFACTORS INFLUENCING THE DECISION TO PROCEED WITH PLANNED OOCYTE CRYOPRESERVATION: IMPACT OF FINANCIAL COVERAGE, RACE AND OTHER DETERMINANTS
Antoun M, Huttler A, Morse B, Thornton K, Penzias A, Sakkas D, Vaughan D. FACTORS INFLUENCING THE DECISION TO PROCEED WITH PLANNED OOCYTE CRYOPRESERVATION: IMPACT OF FINANCIAL COVERAGE, RACE AND OTHER DETERMINANTS. Fertility And Sterility 2025, 124: e37. DOI: 10.1016/j.fertnstert.2025.07.158.Peer-Reviewed Original Research