Adjunct Faculty
Adjunct faculty typically have an academic or research appointment at another institution and contribute or collaborate with one or more School of Medicine faculty members or programs.
Adjunct rank detailsAndrea Danese
Professor AdjunctAbout
Research
Publications
2025
The 2025 ESCAP Research Academy workshop: advancing mechanistic insights and early intervention strategies for psychological trauma
Revet A, Bolhuis K, Young H, Danese A, Mansuy I, Clemens V, Bui E, Fegert J, Riccioni A, Rolling J, Schlaegel K, Schröder C, Hillegers M, Klauser P. The 2025 ESCAP Research Academy workshop: advancing mechanistic insights and early intervention strategies for psychological trauma. European Child & Adolescent Psychiatry 2025, 1-3. PMID: 41410787, DOI: 10.1007/s00787-025-02907-2.Peer-Reviewed Original ResearchPTSD and suPAR: A multicohort investigation of chronic inflammation
Bourassa K, Moffitt T, Arseneault L, Barrett-Young A, Danese A, Garrett M, Houts R, Matthews T, Poulton R, Ramrakha S, Sprinckmoller S, Sugden K, Williams B, Beckham J, Ashley-Koch A, Kimbrel N, Fisher H, Theodore R, Caspi A, Rasmussen L. PTSD and suPAR: A multicohort investigation of chronic inflammation. Brain Behavior And Immunity 2025, 131: 106159. PMID: 41167286, PMCID: PMC12648567, DOI: 10.1016/j.bbi.2025.106159.Peer-Reviewed Original ResearchConceptsPosttraumatic stress disorderSoluble urokinase plasminogen activator receptorLifetime historyDunedin StudyDiagnosis of posttraumatic stress disorderHistory of posttraumatic stress disorderLifetime history of posttraumatic stress disorderStress-related psychiatric disordersAssociation of posttraumatic stress disorderC-reactive proteinSystemic chronic inflammationDunedin Multidisciplinary Health and Development StudyAssociated with soluble urokinase plasminogen activator receptorPoor healthChronic inflammationInterleukin-6Stress disorderPsychiatric disordersInflammatory biomarkersLevels of soluble urokinase plasminogen activator receptorStressful eventsAssociated with poor healthClinical cohortE-RiskCohort of medical patientsWhy do attention‐deficit/hyperactive disorder and/or autism traits place adolescents at risk for depression? Protocol for a longitudinal comparison of the mediating role of emotion regulation deficits versus emotional burden
Sonuga‐Barke E, Palmer M, Griffiths K, Wyatt A, Danese A, Chandler S, Stahl D, Lukito S, Pavlopoulou G, Simonoff E, team T. Why do attention‐deficit/hyperactive disorder and/or autism traits place adolescents at risk for depression? Protocol for a longitudinal comparison of the mediating role of emotion regulation deficits versus emotional burden. JCPP Advances 2025 DOI: 10.1002/jcv2.70052.Peer-Reviewed Original ResearchEmotion regulation deficitsAttention-deficit/hyperactivity disorderRegulation deficitsEmotion dysregulationDepression riskMeasures of attention-deficit/hyperactivity disorderAttention‐deficit/hyperactivity disorder traitsAssociated with attention-deficit/hyperactivity disorderDiagnosis of attention-deficit/hyperactivity disorderCross-lagged path modelPresence of autismEmotional burdenDepressive symptomsCognitive abilitiesStructural equation modelingSelf-esteemAutismDefinition of EDDepressionIntervention targetsMedical statusEmotionsUpset eventsDepression levelsPath modelChildren's Sensitivity to Facial Emotional Expressions: The Mediating Roles of Maternal Warmth and Home Environment
Milojevich H, Dickerson K, Arseneault L, Caspi A, Kim‐Cohen J, Danese A, Moffitt T, Odgers C. Children's Sensitivity to Facial Emotional Expressions: The Mediating Roles of Maternal Warmth and Home Environment. Developmental Science 2025, 28: e70077. PMID: 41058470, PMCID: PMC12614446, DOI: 10.1111/desc.70077.Peer-Reviewed Original ResearchConceptsRecognition of negative emotionsMaternal warmthIntelligence quotientIdentification of emotionsWithin-family analysesNegative emotionsMediation roleChildren exposed to adversityFacial emotional expressionsWithin-familyHigh-risk sampleSame-sex twinsSocioeconomic statusChildren's intelligence quotientChild IQFacial emotionsBritish twinsChildren's sensitivityChildren's abilityEmotional expressionChildhood victimizationCo-TwinSocial functioningSelf-RegulationFacial expressionsMental health of children and young people in the WHO Europe region
Tarasenko A, Josy G, Minnis H, Hall J, Danese A, Lau J, Cortese S, Stringaris A, Redlich C, Ougrin D. Mental health of children and young people in the WHO Europe region. The Lancet Regional Health - Europe 2025, 57: 101459. PMID: 41132774, PMCID: PMC12541636, DOI: 10.1016/j.lanepe.2025.101459.Peer-Reviewed Original ResearchMental health problemsMental healthYouth mental health crisisHealth problemsMental health of childrenYoung peopleEvidence-based careCommunity-based servicesMental health crisisWHO Europe regionMental health disordersHealth of childrenGrown childrenHealth disordersMilitary conflictRobust researchImplementation strategiesSeries paperEurope regionClimate crisisHealth crisisYouthCOVID-19 pandemicCrisisCost-effectiveA pragmatic randomized controlled trial of cognitive therapy for post‐traumatic stress disorder in children and adolescents exposed to multiple traumatic stressors: the DECRYPT trial
Meiser-Stedman R, Allen L, Ashford P, Beeson E, Byford S, Danese A, Farr A, Finn J, Goodall B, Grainger L, Hammond M, Harmston R, Humphrey A, King D, Lofthouse K, Mahoney-Davies G, Miles S, Moore J, Morant N, Robertson S, Shepstone L, Sims E, Stallard P, Swanepoel A, Trickey D, Trigg K, Vishwakarma R, Wilson J, Dalgleish T, Smith P. A pragmatic randomized controlled trial of cognitive therapy for post‐traumatic stress disorder in children and adolescents exposed to multiple traumatic stressors: the DECRYPT trial. World Psychiatry 2025, 24: 422-434. PMID: 40948050, PMCID: PMC12434375, DOI: 10.1002/wps.21355.Peer-Reviewed Original ResearchPost-traumatic stress disorderTreatment-as-usualCT-PTSDTF-CBTCRIES-8Months post-randomizationCognitive therapyStress disorderPragmatic Randomized Controlled TrialMental disordersTotal anxietyRandomized controlled trial of cognitive therapyMeasures of post-traumatic stress disorderTrauma-focused cognitive-behavioral therapyTrial of cognitive therapyRevised Impact of Event ScaleCognitive-behavioral therapyComorbid mental disordersComplex PTSD diagnosisParent-reported emotional difficultiesMultiple trauma exposuresPost-treatmentImpact of Event ScaleUK mental health servicesPost-randomizationEnhancing rigour and contextual sensitivity in digital mental health interventions
Weisz J, Steinberg J, Sun J, Mair P, Fitzpatrick O, Danese A, Adams K, Ougrin D. Enhancing rigour and contextual sensitivity in digital mental health interventions. The Lancet Primary Care 2025, 1: 100048. DOI: 10.1016/j.lanprc.2025.100048.Peer-Reviewed Original ResearchEmotional burden in school as a source of mental health problems associated with ADHD and/or autism: Development and validation of a new co‐produced self‐report measure
Lukito S, Chandler S, Kakoulidou M, Griffiths K, Wyatt A, Funnell E, Pavlopoulou G, Baker S, Stahl D, Sonuga‐Barke E, Sonuga‐Barke E, Chandler S, Danese A, Funnell E, Downs J, Griffiths K, Kakoulidou M, Low L, Lukito S, Prasad U, Roberts A, Simonoff E, Stahl D, Wyatt A, Pavlopoulou G, Hurry J, Baker S, Moore G, Ougrin D, Roestorf A, Kirkbride R, Lewis C, Altimimi J, Balwani B, Barnes S, Boyens T, Glen Z, Harris C, Hillman C, Harvey‐Nguyen L, Jackson I, Johnson A, Ly E, Matejko M, Poulton D, Rose A, Webb D, Wilson A. Emotional burden in school as a source of mental health problems associated with ADHD and/or autism: Development and validation of a new co‐produced self‐report measure. Journal Of Child Psychology And Psychiatry 2025, 66: 1577-1592. PMID: 40707015, PMCID: PMC12447693, DOI: 10.1111/jcpp.70003.Peer-Reviewed Original ResearchConceptsEmotion regulation deficitsMental health problemsIntensity of negative emotionsPredictive of higher depressionSelf-report measuresIntense emotional reactionsSelf-report questionnairesClinically validated scalesMental health risksRegulation deficitsADHD groupAutism groupNeurotypical adolescentsHigher depressionNeurotypical peersADHDNegative emotionsPsychometric propertiesSecondary school studentsAutismSchool InventoryEmotional reactionsCue frequencyUpset eventsLevels of EBEffects of a brief digital problem-solving intervention on depression and anxiety symptoms in Ukrainian children and adolescents displaced by war: a crossover, randomised controlled trial
Weisz J, Steinberg J, Sun J, Mair P, Fitzpatrick O, Karapata N, Yusyn M, Sood G, Danese A, Adams K, Ougrin D. Effects of a brief digital problem-solving intervention on depression and anxiety symptoms in Ukrainian children and adolescents displaced by war: a crossover, randomised controlled trial. The Lancet Primary Care 2025, 1: 100001. DOI: 10.1016/j.lanprc.2025.100001.Peer-Reviewed Original ResearchDigital mental health interventionsInternalising symptomsPost-intervention assessmentRandomised controlled trialsMean symptom scoresIntention-to-treat sampleControlled TrialsMental health careProblem-solving interventionMental health interventionsRisk of depressionControl groupSymptom scoresOpen Science FrameworkIntention-to-treat analysisAnxiety symptomsElevated symptomsContext-specific adaptationsSymptomatic youthHealth interventionsBaseline symptomsHealth careLinear mixed-effects modelsProfessional careSchool grades 5Childhood adversity as a risk factor for autoimmune disease: A systematic review and meta-analysis with implications for psychiatry
Jesuthasan J, Watson C, Hafeez D, Lynch-Kelly K, Danese A, Pollak T. Childhood adversity as a risk factor for autoimmune disease: A systematic review and meta-analysis with implications for psychiatry. Brain Behavior And Immunity 2025, 128: 643-653. PMID: 40320015, DOI: 10.1016/j.bbi.2025.04.036.Peer-Reviewed Original ResearchRisk of biasChildhood adversityDisease in adulthoodMeta-analysisSystematic reviewSevere mental illnessHigh risk of biasRisk factorsExposure to childhood adversityAssociated with childhood adversityAutoimmune diseasesFunnel plot inspectionRates of childhood adversityHistory of childhood adversityPeer-reviewed studiesEnvironmental risk factorsMental illnessAutoimmune disordersEgger's testElectronic databasesAetiology of autoimmune disordersPublication biasPrevention of autoimmune diseasesEffect sizeDysregulated immune response