Alexander Jordan, MD
Assistant Professor of Medicine (Medical Oncology & Hematology)Cards
About
Research
Publications
2026
A context-augmented large language model for accurate precision oncology medicine recommendations
Jun H, Tanaka Y, Johri S, Camp S, Bao E, Carvalho F, Gui D, Jordan A, Labaki C, Martin S, Nagy M, O'Meara T, Pappa T, Pimenta E, Saad E, Yang D, Gillani R, Tewari A, Reardon B, Van Allen E. A context-augmented large language model for accurate precision oncology medicine recommendations. Cancer Cell 2026, 44: 676-685.e4. PMID: 41544626, PMCID: PMC12811686, DOI: 10.1016/j.ccell.2025.12.017.Peer-Reviewed Original Research
2024
Clinical and genomic features of classical and basal transcriptional subtypes in pancreatic cancer
Singh H, Xiu J, Kapner K, Yuan C, Narayan R, Oberley M, Farrell A, Surana R, Huffman B, Perez K, Cleary J, Jordan A, Costa A, Williams H, Raghavan S, Weinberg B, Pishvaian M, Shroff R, Goel S, Dougan S, Nowak J, Spetzler D, Sledge G, Wolpin B, Aguirre A. Clinical and genomic features of classical and basal transcriptional subtypes in pancreatic cancer. Clinical Cancer Research 2024, 30: 4932-4942. PMID: 39283131, PMCID: PMC12267046, DOI: 10.1158/1078-0432.ccr-24-1164.Peer-Reviewed Original ResearchAdultAgedAlbuminsAntineoplastic Combined Chemotherapy ProtocolsBiomarkers, TumorDeoxycytidineFemaleFluorouracilGemcitabineGene Expression ProfilingGene Expression Regulation, NeoplasticGenomicsHumansIrinotecanKaplan-Meier EstimateLeucovorinMaleMiddle AgedMutationOxaliplatinPaclitaxelPancreatic NeoplasmsPrognosisProto-Oncogene Proteins p21(ras)Mechanisms of resistance to oncogenic KRAS inhibition in pancreatic cancer
Dilly J, Hoffman M, Abbassi L, Li Z, Paradiso F, Parent B, Hennessey C, Jordan A, Morgado M, Dasgupta S, Uribe G, Yang A, Kapner K, Hambitzer F, Qiang L, Feng H, Geisberg J, Wang J, Evans K, Lyu H, Schalck A, Feng N, Lopez A, Bristow C, Kim M, Rajapakshe K, Bahrambeigi V, Roth J, Garg K, Guerrero P, Stanger B, Cristea S, Lowe S, Baslan T, Van Allen E, Mancias J, Chan E, Anderson A, Katlinskaya Y, Shalek A, Hong D, Pant S, Hallin J, Anderes K, Olson P, Heffernan T, Chugh S, Christensen J, Maitra A, Wolpin B, Raghavan S, Nowak J, Winter P, Dougan S, Aguirre A. Mechanisms of resistance to oncogenic KRAS inhibition in pancreatic cancer. Cancer Discovery 2024, 14: 2135-2161. PMID: 38975874, PMCID: PMC11528210, DOI: 10.1158/2159-8290.cd-24-0177.Peer-Reviewed Original Research
2022
Emerging Role of Targeted Therapy in Metastatic Pancreatic Adenocarcinoma
Huffman B, Ellis H, Jordan A, Freed-Pastor W, Perez K, Rubinson D, Sethi N, Singh H, Surana R, Wolpin B, Aguirre A, Cleary J. Emerging Role of Targeted Therapy in Metastatic Pancreatic Adenocarcinoma. Cancers 2022, 14: 6223. PMID: 36551707, PMCID: PMC9776746, DOI: 10.3390/cancers14246223.Peer-Reviewed Original Research
2021
COVID‐19 outcomes in hospitalized patients with active cancer: Experiences from a major New York City health care system
Fu C, Stoeckle J, Masri L, Pandey A, Cao M, Littman D, Rybstein M, Saith S, Yarta K, Rohatgi A, Makarov D, Sherman S, Morrissey C, Jordan A, Razzo B, Theprungsirikul P, Tsai J, Becker D. COVID‐19 outcomes in hospitalized patients with active cancer: Experiences from a major New York City health care system. Cancer 2021, 127: 3466-3475. PMID: 34096048, PMCID: PMC8239692, DOI: 10.1002/cncr.33657.Peer-Reviewed Original Research
2020
Dual Targeting of Mesothelin and CD19 with Chimeric Antigen Receptor-Modified T Cells in Patients with Metastatic Pancreatic Cancer
Ko A, Jordan A, Tooker E, Lacey S, Chang R, Li Y, Venook A, Tempero M, Damon L, Fong L, O'Hara M, Levine B, Melenhorst J, Plesa G, June C, Beatty G. Dual Targeting of Mesothelin and CD19 with Chimeric Antigen Receptor-Modified T Cells in Patients with Metastatic Pancreatic Cancer. Molecular Therapy 2020, 28: 2367-2378. PMID: 32730744, PMCID: PMC7647666, DOI: 10.1016/j.ymthe.2020.07.017.Peer-Reviewed Original ResearchImmunotherapy in hepatocellular carcinoma: Combination strategies
Jordan A, Wu J. Immunotherapy in hepatocellular carcinoma: Combination strategies. World Journal Of Meta-Analysis 2020, 8: 190-209. DOI: 10.13105/wjma.v8.i3.190.Peer-Reviewed Original ResearchOxidative Phosphorylation Promotes Primary Melanoma Invasion
Salhi A, Jordan A, Bochaca I, Izsak A, Darvishian F, Houvras Y, Giles K, Osman I. Oxidative Phosphorylation Promotes Primary Melanoma Invasion. American Journal Of Pathology 2020, 190: 1108-1117. PMID: 32142731, PMCID: PMC7237828, DOI: 10.1016/j.ajpath.2020.01.012.Peer-Reviewed Original Research
2019
Peripheral Blood T-Cell Fitness Is Diminished in Patients With Pancreatic Carcinoma but Can Be Improved With Homeostatic Cytokines
Xu J, Sai H, Li Y, Jordan A, McGettigan S, Chen J, Bedoya F, Fraietta J, Gladney W, Melenhorst J, Beatty G. Peripheral Blood T-Cell Fitness Is Diminished in Patients With Pancreatic Carcinoma but Can Be Improved With Homeostatic Cytokines. Cellular And Molecular Gastroenterology And Hepatology 2019, 8: 656-658.e6. PMID: 31398492, PMCID: PMC6889367, DOI: 10.1016/j.jcmgh.2019.07.008.Peer-Reviewed Original Research
2014
A Diverse Array of Cancer-Associated MTOR Mutations Are Hyperactivating and Can Predict Rapamycin Sensitivity
Grabiner B, Nardi V, Birsoy K, Possemato R, Shen K, Sinha S, Jordan A, Beck A, Sabatini D. A Diverse Array of Cancer-Associated MTOR Mutations Are Hyperactivating and Can Predict Rapamycin Sensitivity. Cancer Discovery 2014, 4: 554-563. PMID: 24631838, PMCID: PMC4012430, DOI: 10.1158/2159-8290.cd-13-0929.Peer-Reviewed Original ResearchAnimalsAntibiotics, AntineoplasticCell Line, TumorDatabases, FactualHEK293 CellsHeLa CellsHumansMAP Kinase Signaling SystemMCF-7 CellsMechanistic Target of Rapamycin Complex 1Mechanistic Target of Rapamycin Complex 2MiceMice, NudeMultiprotein ComplexesMutationNeoplasmsNeoplasms, ExperimentalProtein Kinase InhibitorsSirolimusTOR Serine-Threonine KinasesXenograft Model Antitumor Assays
Clinical Care
Overview
Clinical Specialties
Gastrointestinal Oncology
Board Certifications
Medical Oncology
- Certification Organization
- AB of Internal Medicine
- Original Certification Date
- 2025
Internal Medicine
- Certification Organization
- AB of Internal Medicine
- Original Certification Date
- 2020
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