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Serena Susan Spudich, MD, MA

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Gilbert H. Glaser Professor of Neurology
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Additional Titles

Division Chief, Neurological Infections & Global Neurology

Co-Director, Yale Center for Brain & Mind Health

Affiliated Faculty, Yale Institute for Global Health

About

Titles

Gilbert H. Glaser Professor of Neurology

Division Chief, Neurological Infections & Global Neurology; Co-Director, Yale Center for Brain & Mind Health; Affiliated Faculty, Yale Institute for Global Health

Appointments

Other Departments & Organizations

Education & Training

Fellow
University of California at San Francisco (2004)
Fellow
Harvard Medical School (2003)
Resident
Harvard Medical School (2002)
Resident
University of Washington School of Medicine (1999)
Intern
University of Washington School of Medicine (1998)
MD
University of California at San Francisco (1997)
MA
Stanford University, Philosophy of Science (1992)
BA
Stanford University, Human Biology/Humanities (1991)

Research

Overview

Medical Research Interests

Acquired Immunodeficiency Syndrome; Antiviral Agents; Biomarkers; Cerebrospinal Fluid; COVID-19; Dementia; HIV; Nervous System; Neurodegenerative Diseases; Neuroinflammatory Diseases; Neurology; Positron-Emission Tomography; Post-Acute COVID-19 Syndrome; Virology

Public Health Interests

Biomarkers; HIV/AIDS; Immunology; Infectious Diseases; Viruses; COVID-19

Research at a Glance

Publications Timeline

A big-picture view of Serena Susan Spudich's research output by year.

Publications

2026

2025

  • A psychometric assessment of the Patient Health Questionnaire-9 for people living with acutely-treated HIV in Thailand
    Hamby T, Pinyakorn S, Frndak S, Chomchey N, Kanaprach R, Chan P, Schluck G, Kroon E, Suttichom D, Poonpitak L, Sriplienchan S, Spudich S, Phanuphak N, Trautmann L, Paul R, Sacdalan C, Crowell T, Group T. A psychometric assessment of the Patient Health Questionnaire-9 for people living with acutely-treated HIV in Thailand. Psychiatry Research Communications 2025, 6: 100242. PMID: 42369326, PMCID: PMC13308563, DOI: 10.1016/j.psycom.2025.100242.
    Peer-Reviewed Original Research
  • Neuroaxonal Injury in Acute HIV Infection and Following Immediate Antiretroviral Therapy
    Chan P, Sacdalan C, Pinyakorn S, Kroon E, Colby D, Promsena P, Sriplienchan S, Phanuphak N, Vasan S, Valcour V, Paul R, Gisslén M, Zetterberg H, Trautmann L, Spudich S. Neuroaxonal Injury in Acute HIV Infection and Following Immediate Antiretroviral Therapy. Journal Of Infectious Diseases 2025, 233: e913-e922. PMID: 41254882, PMCID: PMC13127774, DOI: 10.1093/infdis/jiaf583.
    Peer-Reviewed Original Research
  • Greater Accumulation of Brain White Matter Hyperintensities in People Diagnosed and Treated During Acute HIV Compared With People Without HIV
    Holroyd K, Chan P, Sacdalan C, Dumrongpisutikul N, Sriplienchan S, Promensa P, Sailasuta P, Pothisri M, Puttamaswin S, Vasan S, Valcour V, Trautmann L, Spudich S, Paul R, Bolzenius J. Greater Accumulation of Brain White Matter Hyperintensities in People Diagnosed and Treated During Acute HIV Compared With People Without HIV. Neurology 2025, 105: e214445. PMID: 41172230, PMCID: PMC12817266, DOI: 10.1212/wnl.0000000000214445.
    Commentaries, Editorials and Letters
  • Neurosymptomatic Cerebrospinal Fluid Escape Is a Central Nervous System–Focused Form of Antiretroviral Therapy Treatment Failure
    Kincer L, Dravid A, Zhou S, Vercesi R, Spudich S, Gisslén M, Price R, Cinque P, Joseph S. Neurosymptomatic Cerebrospinal Fluid Escape Is a Central Nervous System–Focused Form of Antiretroviral Therapy Treatment Failure. Open Forum Infectious Diseases 2025, 13: ofaf659. PMID: 41488692, PMCID: PMC12760783, DOI: 10.1093/ofid/ofaf659.
    Peer-Reviewed Original Research
  • Antiretroviral Therapy Intensification With Dolutegravir and/or Maraviroc Did Not Affect HIV-1 Cell-Associated DNA, RNA, and 2­–LTR Circles Over 12 Weeks
    Reed J, Hall L, McKhann A, Kwak G, Goecker E, Coombs R, Chen H, Roa J, Vecchio A, Daar E, Hunt P, Marra C, Campbell T, Ma Q, Swaminathan S, Macatangay B, Morse G, Miller T, Rusin D, Ha B, Alston-Smith B, Paul R, Letendre S, Spudich S, Greninger A. Antiretroviral Therapy Intensification With Dolutegravir and/or Maraviroc Did Not Affect HIV-1 Cell-Associated DNA, RNA, and 2­–LTR Circles Over 12 Weeks. Open Forum Infectious Diseases 2025, 12: ofaf594. PMID: 41141451, PMCID: PMC12548372, DOI: 10.1093/ofid/ofaf594.
    Peer-Reviewed Original Research
  • Olfactory Dysfunction After SARS-CoV-2 Infection in the RECOVER Adult Cohort
    Horwitz L, Becker J, Huang W, Akintonwa T, Hornig-Rohan M, Maranga G, Adams D, Albers M, Ayache M, Berry J, Brim H, Bryan T, Charney A, Clark R, Cortez M, D’Anza B, Davis H, Donohue S, Erdmann N, Flaherman V, Fong T, Frontera J, Goldberg M, Goldman J, Harkins M, Hodder S, Jacoby V, Jagannathan P, Jia X, Kelly J, Krishnan J, Kumar A, Laiyemo A, Levitan E, Martin J, McCaffrey K, McComsey G, Metz T, Murthy G, Nguyen H, Okumura M, Parry S, Parthasarathy S, Patterson T, Peluso M, Sorochinsky C, Walker T, Wiegand S, Wiley Z, Wisnivesky J, Ashktorab H, Foulkes A, Lee-Iannotti J, Han J, Marconi V, Ofotokun I, Patzer R, Walker T, Abraham R, Aguilar F, Ahmadi-Izad G, Ahmed D, Alvarez A, Anderson B, Asencios W, Beaty C, Bedi B, Berry J, Boone D, Bower M, Bremner J, Brent C, Brown-Smith K, Bull R, Capo G, Carl-Igwe K, Chitadze C, Chukwumerije N, Clyburn E, Collins S, Costello J, Couture G, Craft A, Cui X, del Rio C, Detelich J, Dixon C, Dow J, Doyle D, Elchommali J, Elsey I, Franks N, Gallini J, Gutter E, Harding J, Hernandez L, Holloway C, Ifejika C, Jasarevic R, Javia V, Jeter M, Joseph Y, Juarez M, Kirkpatrick C, Koumanelis A, Krishnan S, Leon J, Lew V, Maier C, Makkaoui N, Maroney M, Martin C, Mbogo L, McCaslin A, McIntyre J, Moanna A, Montoya M, Morales E, Moran C, Murray C, Nelson R, Nguyen T, Ojoawo B, Osinski E, Oviedo S, Paredes-Gaitan Y, Prude M, Ramakrishnan G, Rebolledo P, Roberts M, Robinson K, Rogers C, Rouphael N, Searles C, Segall M, Shah A, Silva R, Simpson C, Simpson-Derrell K, Sirajud-Deen T, Stroud J, Suthar M, Sylber C, Sylvera A, Teunis L, Thomas K, Titanji K, Toy C, Truong A, Vaccarino V, Varney K, Vyas K, Vyas K, Walkow M, Wesley T, Winston J, Winter T, Wongtrakool C, Cribbs S, Collins O, Fournier C, Francis A, Hang T, Ingram K, Lainez J, Rubinsztain L, Yeung H, Wiley Z, Ager A, Gray N, Grimes A, Gromer D, Hewitt L, Huerta C, Johnson B, Kelley C, Khalil L, Kleinhenz D, Koumanelis A, Kozoman R, Lee M, Lewis K, Litvack M, Maramba T, Mehta C, Panganiban B, Rahman K, Smith V, Stringer A, Tolbert M, Traenkner J, Unterberger K, Wang H, Wimberly E, Yang Q, Ryerson A, Hjortsberg R, Hudgins A, Martinez M, Neuman R, Thompson S, Agu C, Pemu P, Afani A, Ariri C, Dandy A, Harper K, Ibeawuchi C, Lawrence B, Morgan-Billingslea J, Ojemakinde E, Smith K, Levy B, Aikawa M, Baden L, Baslet G, Bennett L, Bhattacharyya S, Buring J, Cagnina R, Chen L, Clark C, Cohen P, Czeisler C, Estill P, Gay E, Hong J, Lamas D, Lay S, Levy-Carrick N, Manson J, Monafrared T, Redline S, Remis E, Schilkrut D, Sesso H, Solomon S, Sparks J, Spencer L, Systrom D, Thu P, Walt D, Washko G, Whittelsey M, Wiener R, Bassett I, Alba G, Aung T, Fitch K, Ginns L, Haas J, Hu Y, Juelg B, Kanjilal D, Kim A, Klerman E, Lewis G, Musa A, Ojikutu B, Perlis R, Rosand J, Wallace Z, Xerras D, Zionts D, Mullington J, Collier A, Fong T, Haack M, Hauser K, Maley J, Quintana Y, Shaughnessy L, Stephenson K, Thomas R, Torres R, Marathe J, Duffy E, Hamburg N, O'Connor G, Zhang H, John J, Ticotsky A, Ward H, Blazey-Martin D, Ghamloush M, Jordan M, Kogelman L, Marryshow T, Erdmann N, Levitan E, Tita A, Armstrong D, Binkley S, Blackwell K, Causey A, Cook F, Domingo J, Donahue C, Eady M, Edberg J, Forehand K, Frazier P, Garcia-McClaney N, Garner M, Gray B, Hall W, Hart C, Hebson C, Hidalgo B, Higgins B, Holtzapfel K, Horton G, Jinright A, Judd S, Kennedy T, Kirkwood L, Maier M, McCormack P, Mitchell K, Montgomery A, Nieters D, Peralta-Carcelen M, Pilco J, Powell L, Royster J, Shevin R, Skipworth S, Spurgeon L, Steele C, Vines J, Ware G, Wilson R, Woodruff D, Young B, Gillespie M, Daniel C, Hansel J, Wu J, Carton T, Miele L, Brown T, Sutherland E, Fuloria J, Datri P, Hagensee M, Leggio C, Perkins A, Trauth A, Trotter S, Van Deerlin A, Weiser S, Young M, Ashktorab H, Brim H, Laiyemo A, Sherif Z, Durrani S, Nezamloo A, Ngwa J, Njoku N, Gentil M, Mehari A, Solemani A, Chang L, Thuluvath P, Alemu M, Anderson J, Chauhan M, Cho S, Goodman K, Lanke G, Lebron R, Maheshwari A, Ok J, To C, Hodder S, Bardes J, Dominique-Villanueva D, Juskowich J, Reece R, Sarwari A, Shellito J, Greenway F, Kirwan J, Rodemann G, Rosen C, Arruda A, Brunet T, Emery I, Roelke T, Berger P, Black L, Hoover S, Tjarks B, Fonseca V, Gupta S, Longo M, Yang M, Shikuma C, Chow D, MarGangcuangco L, Castro M, Bengtson C, Howard T, Koontz B, Spikes L, Simmons C, Whiteheart S, Garvy B, Wood J, Marshall G, Garla V, Kuebler J, Nandi U, Vasey A, Warren D, Dickinson J, VanWagoner T, Bogie A, Heyanka D, James J, Scott J, Sukhera F, Luciano Roman C, Perez Frontera S, Santana Bagur J, Klein J, Krishnan J, Lin J, Muramatsu N, Prabhakar B, Prendergast H, Vanden Hoek T, Adams D, Baker A, Barbera S, Basu S, Bleasdale S, Boyd A, Breiter T, Buhimschi I, Carrithers M, Chalamalla R, Chestek D, Cook J, Darbar D, Dasgupta R, Davis Blakley F, DeLisa J, Diviak K, Donlon M, Dworkin M, Ellison A, Flanigan C, Freedman M, Gerald L, Giles W, Gordon H, Hammad B, Hasek S, Hasse W, Hryniewicka M, Illendula S, Ismail N, Jain A, Jennette K, Kadubek G, Kent D, Kent D, Kim K, Kotini-Shah P, Large L, Lash J, Lu J, Mahamed A, Malchenko S, Martinez M, Mauntel-Medici C, McCauley M, Menchaca M, Mermelstein R, Moreno D, Morrissy L, Musick H, Norwick L, Novak R, Ortiz M, Patel K, Perez N, Pliskin N, Pope S, Prasad B, Predki B, Quigley J, Ramchandran R, Ramirez A, Rappe S, Rehman J, Rowley M, Rudraraju G, Rutherfoord M, Sculley J, Smith-Mack J, Sun J, Tartt N, Villanueva L, Warfield Kelly S, Yazici C, Certa M, Chessier E, Everett E, Kindred E, Harris P, Sudhindra P, Olds L, Aponte-Soto L, Del Rios M, Diaz M, Ibanez A, Rolon C, Cranford S, Brown D, Dixon J, Gale L, Hammerl S, Hartwig K, Madineni A, Swearingen P, Hendrickson M, Noland S, Terlinde T, Hobbs B, Stewart de Ramirez S, Bolliger D, Boyineni J, Chebrolu P, Curry H, Donohue S, Edmonds S, Kelly S, Maholovich P, Sader S, Thompson T, Welter H, Woolley B, Hafner J, Hanson K, Hutton R, Charney A, Kovatch P, Merad M, Nadkarni G, Wisnivesky J, Aberg J, Ascolillo S, Bagiella E, Bartram L, Becker J, Beckmann N, Bendl A, Chen B, Civil A, Crawford G, Dhar K, Evo-Ortega L, Fierer D, Gallagher E, Garcia-Sastre A, Gnjatic S, Gray I, Guliyeva S, Harvey-Ingram L, Herrera-Moreno J, Hill M, Horowitz C, Jackson R, Kastrat D, Lala-Trindade A, Lin J, Macaluso N, Marcon K, Meyer D, Morinigo J, Natelson B, Nussenzweig M, Padua T, Putrino D, Richardson L, Russo S, Seifert A, Serri A, Walker J, Yee M, Bateman L, Hess R, Truong D, Alekhina N, Barlocker J, Brown J, Cortez M, Donohue D, Facelli J, Gouripeddi R, Hermansen J, Johnny J, Lindsay A, Lloyd J, Lu Y, Medina J, Morimoto S, Pace L, Rius D, Scholand M, Shah K, Sharareh N, Spivak A, Stringham C, Trinity J, Velinder M, Weaver L, West J, Vernon S, Deakyne Davies S, Gardner E, Buck K, Gonzalez Rivas E, Hawkins K, Oakes J, Sanchez Vazquez W, Horne B, Knowlton K, Woller S, Aguirre B, Anderson J, Bair T, Bosh L, Evans L, Garrett C, Harris D, Herrera K, Iverson L, Jensen M, Juan J, Knight S, Leither L, Maestas H, May H, Zubal S, Erlandson K, Sokol R, Brightman M, Davis D, Feuerriegel E, Fudge H, Garg L, Higgins J, Jolley S, Lockie T, McCandless S, Pitch C, Reusch J, Thurman B, Tran H, West S, Friedman N, Ludwig K, Decker L, Raissy H, Adolphi N, Archuleta D, Bradfute S, Brito R, Elifritz J, Garcia-Soberanez N, Gentry F, Harkins M, Martinez N, Montoya L, Parada A, Quinn D, Ramos A, Sheehan E, Treacher I, McComsey G, Adams C, Andrefsky J, Atieh O, Baissary J, Boldt N, Chemali K, Ciborek E, Conrad A, D’Anza B, Daher J, DiFrancesco K, Foster (Rodgers) T, Gallagher M, Gupta A, Harrill J, Harris P, Jacono F, Kelly J, Koberssy Z, Kumar R, Labbato D, Lim J, Pettinato K, Rodgers M, Rosolia B, Roy A, Sattiraju S, Scott S, Smith B, Tejani V, Tribout M, Yendewa G, Singer N, Ayache M, Barnboym E, Brown A, Chesnick H, Edminston M, Greenwood C, Haghiac M, Kaufman E, Lengu K, Lowenthal R, Malakooti S, Oleson C, Pearman A, Rizea A, Smith C, Washington M, Weinberger E, Heath J, Brennan C, Edmark R, Gutierrez V, Hadlock J, Li S, Magis A, McDonald C, Murray K, Rowen L, Yuan D, Chen P, Banitaba A, Caudill A, Chopra T, Dahlke L, Diaz M, Gudipudi L, Jackman S, Mattison B, Modes M, Nelson C, Nwafor C, Parimon T, Pascual E, Salinas N, Torbati S, Watson S, Tuttle K, Alicic R, Baxter J, Emerson S, Hood S, Kuykendall K, White S, Wilcox L, Goldman J, Algren H, Del Alcazar J, Duven A, Kaneko J, Kim C, Manner P, Mason C, Okada A, Poussier R, Satira R, Wallick J, Chu H, Elias-Warren A, Harteloo A, Logue J, McCaffrey K, Nguyen H, Nambiar A, Patterson T, Potter J, Salehi M, Sharma K, Verduzco-Gutierrez M, Anderson R, Arellanes A, Barajas R, Chauhan S, Clarke G, Farner C, Fischer M, Goldberg M, Hastings G, Heard P, Hernandez J, Herrera I, Infante E, Johnson H, Jones J, Kellogg D, Kraig E, Longoria L, Okafor E, Patterson J, Pinones A, Reeves W, Scholler I, Seshadri S, Shah P, Shah D, Smith M, Soileau B, Solis P, Stoebner C, Sullivan M, Taylor B, Tragus R, Tsevat J, Hasbani K, Saade G, Hernandez Martinez G, Recabarren C, Sharma K, Paredes C, Alvarado S, Kumar A, Maldonado Y, Utz P, Blish C, Go M, Jagannathan P, Singh U, Ahuja N, Blomkalns A, Bonilla H, Brotherton R, Clinton K, Dingankar V, Geng L, Haddad F, Jamero C, Jee K, Jia X, Khurana N, Miglis M, O'Conor E, Olszewski K, Pathak D, Quintero O, Saperia C, Scott J, Urdaneta A, Varkey M, Nikolich J, Parthasarathy S, Ernst K, Esquivel D, Harris D, Harris S, Hernandez M, Hsu H, James M, Karnafel M, Knox K, Koleski A, LaFleur B, Lambert B, LaRue S, Lutrick K, Merchant N, Morton C, Mosier J, Olorunnisola T, Peralta J, Pilling W, Pogreba-Brown K, Rischard F, Ryan L, Smith T, Snyder M, Subbian V, Suhr K, Reiman E, Lee-Iannotti J, Autry L, Beydoun H, Borwege S, Copeland J, DiLise-Russo M, Fadden S, Gomez I, Grischo G, Hartley W, Hillier L, Ismail H, Iusim S, Kala M, Kim D, Murthy G, Unzek S, Vadovicky S, Veres S, Bime C, Hansen L, Hughes T, Khalid S, Lieberman D, Soto F, Wilson C, Zapien A, Deeks S, Kelly J, Martin J, Peluso M, Anderson G, Anglin K, Argueta U, Asare K, Buitrago M, Chang Song C, Clark A, Conway E, Del Castillo N, Deswal M, Durstenfeld M, Eilkhani E, Eun A, Fehrman E, Figueroa T, Flores D, Grebe H, Henrich T, Hoh R, Hsue P, Huang B, Ibrahim R, Kerbleski M, Kirtikar R, Lew M, Lombardo J, Lopez M, Luna M, Marquez C, Munter S, Ngo L, Pineda-Ramirez J, Prather A, Rhoads K, Rodriguez A, Romero J, Ryder D, So M, Somsouk M, Tai V, Tran B, Uy J, Valdivieso D, Verma D, Williams M, Zamora A, Flaherman V, Jacoby V, Araya N, Arellano-Mechor C, Basi Y, Chang A, Christopher L, De La Torre I, Gade S, Guerreros E, Laleau V, Martin Herz S, Monzon V, Oceguera Barragan Y, Rait M, Salem M, Tolentino M, Metz T, Lamb D, Mcfarland E, Nelsen A, Phillips K, Schlater S, Sharma J, Sowles A, Valencia Vazquez J, Zaldivar M, Rouse D, Allard D, Beati L, DeMartino A, Lefebvre H, Milano J, Miller E, Hoffman M, Kitto C, Vanneman A, Reddy U, Bousleiman S, Eccheveri S, Gutierrez Y, Loffredo M, Perez A, Ravi R, Zork N, Hughes B, Ferrara J, Longo M, Mitchell M, Esplin M, Palatnik A, Karasti M, Peterson Z, Saffian E, Wiegand S, Fennig K, Snow E, Skupski D, Pao R, Patel R, Zaw H, Plunkett B, Anglemire K, Kapogiannis C, Kearns K, Suresh S, Yee L, Brinson M, Jones^ D, Kominiarek M, Mallett G, Reynolds T, Williams E, Palomares K, Beche I, Graziano-Carrete D, Perez C, Clifton R, Barrett K, Mullowney C, Sandoval G, Weiner S, Gibson K, Dalton W, Desantis B, Gill-Jones P, Pierse A, Polito L, Rosolowski B, Sweet E, Costantine M, Bartholomew A, Cackovic B, Dembroski C, Grobman W, Klopfenstein B, Mast D, McDaniel K, Paglione M, Rigsby C, Hackney^ D, Tita A, Armstrong D, Burrell N, Casey B, Dunn D, Mann M, Hoffman M, Docter O, Fischer L, Phipers J, Thorp J, Clark K, Leatherland M, Timlin S, Parry S, Filipczak A, Long E, McCabe M, Pizzi C, Simhan H, Bauer E, Boyce J, Facco F, Hankle S, Hines R, Hohn M, Muthukrishnan A, Sciurba F, Vargo J, Pacheco L, Cornwell J, DeVolder J, Nounes A, Salazar A, Thibodeaux L, Mendez-Figueroa H, Ortiz F, Rugerio J, Treadway J, Beamon C, Dufresne I, Grinnan C, Phillips H, Pettker C, Perley L, Rink L, Newman L, Abella J, Barnette Q, Bevc C, Beverly J, Ceger P, Croxford J, Cunningham E, Enger M, Fain K, Farris T, Hanlon S, Hines D, Johnson-Lawrence V, Jordan K, Lefebvre C, Linas B, Luukinen B, Mandal M, McKoy N, Nance S, Oakland A, Pasquarelli D, Quiner C, Sembajwe R, Shaw G, Thornburg V, Tosco K, Wright H, Gross R, Hochman J, Horwitz L, Katz S, Troxel A, Adler L, Akinbo P, Almenana R, Bello O, Bhuiyan S, Blachman N, Branski R, Briscoe J, Brosnahan S, Bueler E, Burgos Y, Caplin N, Chaplin D, Chen Y, Cheng S, Choe P, Choi J, Chung A, Church R, Cobos S, Croft N, Cruz Irving A, Del Boccio P, Díaz I, Doshi V, Ebel S, Faustin A, Febres E, Fine J, Fink S, Frontera J, Gallagher R, Gonzalez-Duarte A, Hasson D, Hill S, Islam S, Johnson S, Kansal N, Kenney R, Kewlani D, Lamendola-Essel M, Laynor G, Leon T, Lewczak Z, Linton J, Logan M, Malik N, Mamistvalova L, Mandel H, Maranga G, Mathews P, Mattoo A, Mei T, Mendelsohn A, Mercier E, Millar Vernetti P, Miller M, Mitchell M, Moreira A, Mudumbi P, Nahin E, Nair N, Nekulak J, Owens K, Parent B, Patibandla N, Petrov P, Postelnicu R, Randall I, Rao P, Rapkiewicz A, Rizzo J, Rosas J, Rose C, Saint-Jean C, Santacatterina M, Shah B, Shaukat A, Simon N, Simsir A, Stinson M, Tang W, Tatapudi V, Thawani S, Thomas M, Thorpe L, Tom M, Treiha E, Truong J, Udosen M, Velazquez-Perez J, Vernetti P, Vidal C, Viswanathan A, Wong C, Wood M, Wuller S, Yin S, Young C, Zaretsky J, Zavlunova S, Foulkes A, Karlson E, Murphy S, Ahirwar S, Ahmed S, Ainsworth L, Atchley-Challenner R, Avilach P, Balan T, Benik N, Benoit B, Bind M, Bonaventura W, Boutin N, Brion B, Cagan A, Cai T, Cao T, Castro V, Cerretani X, Chan J, Cheng D, Chibnik L, Ciriello M, Costenbader K, Dimitrov D, Estiri H, Fayad M, Feldman C, Gainer V, Ghosh B, Gollub R, Guan Z, Harris A, Helmer K, Hendrix A, Holzbach A, Huang W, Kaufman D, Keogh D, Kerr J, Klann J, Krishnamoorthy A, Lasky-Su J, Liao K, MacFadden D, Maram A, Martel M, Mendis M, Metta R, Monteiro J, Morales E, Morse R, Nazaire M, Neils G, Nguyen A, Norman J, Paik H, Pant D, Park H, Rabideau D, Reeder H, Rossi-Roh K, Santacroce L, Schlepphorst K, Schulte C, Selvaggi C, Shinnick D, Simons W, Simpson L, St. Jean Flanders M, Strasser Z, Thakrar M, Thaweethai T, Thorn M, Trewett P, Van Fleet D, Wagholikar K, Wang T, Wattanasin N, Weber G, Williams M, Zhang R, Cicek M, Flotte T, Boysen E, Chang N, Ellingworth E, Frisch E, Welch G, Yusuf A, Zahnle N, Cerda M, Clash V, Taylor B, Zissis M, Akintonwa T, Blancero F, Brown H, Carmilani M, Copeland D, Hall Y, kondo K, Lerma L, Lindsay J, Marti H, Maughan C, Minor T, Vincent H, Burns J, Spudich S, Bailey C, Cortez M, Foulkes A, Goff D, Lasky-Su J, Ofotokun I, Stockwell M, Stone J, Taylor B, Utz P, Williams N, Warburton D, Davis H, Erdmann N, Gage Witvliet M, Jain M, Martinez T, McGrath R, Rutter J, Bishof K, Dumitriu D, Goepfert P, Goldman S, Hewitt S, Huentelman M, Karp B, Lachowicz-Scroggins M, Nikolich-Zugich J, Perlowski A, Reeves B, Salazar J, Valantine H, Waldrop D, Anderson K, Aragon L, Azor-Sterlin M, Bander B, Basu L, Bolecek J, Burke C, Carignan E, Castro Baucom L, Chen H, Clash V, Cohen A, Cole S, Coombs K, Copeland V, Covington L, Cox W, Crawford S, Debrosse A, DeRosa R, Diggs M, Doster J, Douglas J, Dunn M, Edwards B, Evans L, Fisher L, Fisher K, Fitzgerald M, Fleming D, Gage Witliet M, Garbutt C, Ghormley T, Godwin T, Gressley A, Gustafson T, Hanlon W, Hassey T, Holmes V, Hornig M, Hornig M, Huff-Davis A, Jackson Love J, Jain N, Jones J, Kaleponi G, Karwowsky J, La Londe-Pinkston J, Lam J, Letts R, Lewis J, Lima J, Lindsay D, Martinez A, McCorkell L, McCray N, McNulty M, Nguyen K, Nichols L, Noriega E, Nunes P, O'Brien L, Ortiz G, Owen S, Page J, Peddie A, Phillips-Lorenzo E, Prentiss L, Raytselis N, Regino L, Rockwell M, Saldino R, Sapunar L, Savage S, Seibert E, Sekar A, Souder A, Spier E, Stanislawczyk M, Stein-Seroussi D, Sullivan C, Taylor E, Taylor K, Terry D, Wallace A, Warner J, White B, Wilensky R, Williams M, Williams N, Williams-Dawson K, Wylam A. Olfactory Dysfunction After SARS-CoV-2 Infection in the RECOVER Adult Cohort. JAMA Network Open 2025, 8: e2533815. PMID: 40996759, PMCID: PMC12464792, DOI: 10.1001/jamanetworkopen.2025.33815.
    Peer-Reviewed Original Research

Clinical Trials

Current Trials

Academic Achievements & Community Involvement

Activities

  • activity

    Investigations in CNS HIV Reservoirs and HIV Cure

  • activity

    Effects of Acute HIV Infection in the Central Nervous System

Clinical Care

Overview

Serena Spudich, MD, MA, is one of only a few neurologists in the United States with specialized training in infections of the nervous system and a clinical practice focusing on neurological issues in patients with HIV.

She primarily cares for patients with HIV who suffer from such neurological problems as cognitive disturbances, memory loss and infections. “Many of these are directly related to HIV,” she says. In addition, she consults with patients who have such infections of the nervous system as Lyme disease and West Nile virus, and those with general neurological disorders.

A professor of neurology at Yale School of Medicine and division chief of neurological infections and global neurology, Dr. Spudich strongly believes patients can lead longer and healthier lives when HIV is diagnosed and treated early. “The example that one patient has proven to be cured of HIV, which was previously thought to be an ‘incurable’ disease, brings hope to the 37 million people worldwide infected with HIV, and to those with other chronic infections that impact the brain,” she says.

Clinical Specialties

Neurology; HIV & AIDs Medicine; Infectious Diseases

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  • Neuroinfectious Disease Research Program

    Lab

    135 College Street, Fl 3

    New Haven, CT 06510

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