Yale Psychiatry Grand Rounds: "Frontiers in Global Mental Health Research & Service Delivery"
January 31, 2025January 31, 2025
"Frontiers in Global Mental Health Research & Service Delivery"
Matthew Basilico, MD, PhD; Yang Jae Lee, MD; Marcos Moreno, MD, fourth-year residents, Yale Department of Psychiatry
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- 12697
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Transcript
- 00:01Hi. Well, thank you very
- 00:02much, doctor Crystal. Oh, sorry.
- 00:05Well, thank you very much,
- 00:06doctor Crystal, for the generous
- 00:08introduction.
- 00:09So, you know, mental illnesses
- 00:11are the leading,
- 00:13leading cause of disability adjusted
- 00:15life years globally. So I
- 00:17think it's very appropriate that,
- 00:18you know, we're having a
- 00:20a grand rounds in global
- 00:21mental health. So before further
- 00:23ado, I wanna introduce,
- 00:25my colleague and co resident,
- 00:26Natje
- 00:27Basilica, who comes to this
- 00:29residency program with a lot
- 00:30of accomplishments.
- 00:32Before his career in medicine,
- 00:34he was the chief of
- 00:36staff for the president of
- 00:37the World Bank, Jim Jim
- 00:38Kim, chief of staff for
- 00:40Paul Farmer. And when I
- 00:41was an undergrad, I actually
- 00:42read a book that he
- 00:44wrote,
- 00:46for my introduction to global
- 00:47health course.
- 00:49And he got his MD
- 00:50PhD from Harvard in economics,
- 00:53and, is, is honored to
- 00:55have him as a colleague.
- 00:56He was also recently voted
- 00:57favorite professor at Harvard by
- 00:59class of twenty twenty five.
- 01:00So he somehow manages to,
- 01:02you know, keep,
- 01:04you know, his teaching responsibilities
- 01:06as well as, you know,
- 01:08being a being an outstanding
- 01:09clinician here. So, before further
- 01:11ado, here's Matt.
- 01:17Thanks so much, Jay. True
- 01:19honor to be up here
- 01:20to speak to every one
- 01:21of you.
- 01:22And, you know, thank you
- 01:23for making this forum where
- 01:24we can explore some, you
- 01:25know, key progress in in
- 01:26this field. So I'll just
- 01:28frame global mental health a
- 01:30little bit.
- 01:31The field,
- 01:32which is, like, a part
- 01:33of the the field of
- 01:34global health is all about
- 01:35inequity. Right? Inequity in, the
- 01:38burden of illness, as Jim
- 01:39mentioned, and equity
- 01:41in access to services.
- 01:42And so, I'm gonna focus
- 01:44a bit of my talk
- 01:45on some of these, on
- 01:46the social determinants of health,
- 01:47some of this unequal burden,
- 01:49but really wanna emphasize and
- 01:51and as as doctor Kristol
- 01:52mentioned that,
- 01:53you know, the the pioneers
- 01:55in our field, but we
- 01:55can say global health or
- 01:57global mental health, have this,
- 01:59you know, unique set of
- 02:00characteristics
- 02:01where they have worked in
- 02:02partnership often for decades and
- 02:04decades,
- 02:05with some, communities in, tremendous
- 02:08need of
- 02:11of, from a health care
- 02:11standpoint. And so I have
- 02:13Paul Farmer up here who's
- 02:14really sort of a pioneer
- 02:15who who works and built
- 02:17organizations in nine different countries.
- 02:18They're working very tightly with
- 02:20communities, and those lessons from
- 02:22on the ground delivery problems
- 02:24are then shared globally,
- 02:26through many political changes,
- 02:28like those that we're going
- 02:28through now and, you know,
- 02:29develop resilient health care delivery,
- 02:32infrastructure
- 02:33and lessons that can be,
- 02:34you know, learned through the,
- 02:36to the whole world. And
- 02:37so Vikram Patel, they're our
- 02:39good friends, but, you know,
- 02:40Vikram is probably the biggest
- 02:41name now in global mental
- 02:42health, was also a psychiatrist
- 02:44in his native
- 02:45India for over twenty years
- 02:46and then used those lessons
- 02:48to become one of the,
- 02:49you know, highest funded, researchers
- 02:50in this area and really
- 02:51a global thought leader bringing
- 02:53these lessons of equity. And
- 02:54I would just point out
- 02:54that I think our next
- 02:55two speakers, both Jay and
- 02:57Marco, has really kind of
- 02:58lived this archetypal model where
- 03:00you're looking for sustained,
- 03:02knowledge generation at the frontier,
- 03:05working with communities in partnership,
- 03:07and then asking how those
- 03:08lessons can translate to,
- 03:10improving, global mental health equity.
- 03:12It's really, exciting to to
- 03:14have been to co resident
- 03:15with them, and and I
- 03:15can't wait to see where
- 03:17their work will go.
- 03:19I'll just talk a little
- 03:20bit about my,
- 03:22my work in economics right
- 03:23here,
- 03:24some interesting findings,
- 03:26from from tools that we
- 03:27use in our discipline that
- 03:29might, have relevance to the
- 03:30ways that we think about,
- 03:31the unequal distribution of mental
- 03:33health disorders globally.
- 03:35And, you know, so kind
- 03:36of to take a recent
- 03:37review, this is from, World
- 03:38Psychiatry in twenty twenty four,
- 03:40a great review, really emphasizing
- 03:42that we know that adverse,
- 03:44you know, social conditions, especially,
- 03:47from anywhere from in utero
- 03:48to, early childhood to adulthood,
- 03:51obviously,
- 03:53affect risk of a variety
- 03:54of mental health disorders.
- 03:57My teaching kind of straddles
- 03:59two fields. One is, development
- 04:01and global health, and the
- 04:02other, this is kind of
- 04:03the first lecture class of
- 04:05kind of devoted to mental
- 04:06health at a we think
- 04:07at a top Egon department,
- 04:08so trying to fuse these
- 04:10two disciplines together.
- 04:11And one of the kind
- 04:12of interesting things that we
- 04:13encounter is that
- 04:15unlike the rest
- 04:16of global health where we
- 04:17have what's called the Preston
- 04:18curve and health naturally gets
- 04:21or, you know, it tends
- 04:22to get better as country
- 04:23incomes improve, We have kind
- 04:25of the opposite,
- 04:27finding in,
- 04:29in, you know, subjective well-being.
- 04:31And you may have seen
- 04:32this on the front page
- 04:34New York Times obituary
- 04:35this month for Richard Easterlin,
- 04:37who
- 04:38found the very famous Easterlin
- 04:40paradox, which is that despite
- 04:41rapid growth in,
- 04:44many countries, we don't see
- 04:45a concomitant rise in well-being.
- 04:48And so this has been
- 04:50thought to be one of
- 04:50the biggest puzzles in macroeconomics.
- 04:52Why does why does economic
- 04:56increase in subjective well-being? And
- 04:57here's just a few examples
- 04:58of this of this chart.
- 04:59And as you you'll see
- 05:00my hypothesis that I'm trying
- 05:02to get at is that,
- 05:04there's a there's a lot
- 05:05going on here in the
- 05:06aggregate social changes happening. This
- 05:08is not just about income
- 05:09changes. It's about other changes
- 05:10in society,
- 05:11sometimes very subtle changes. And
- 05:13if we can better characterize
- 05:14those, especially on a quantitative
- 05:16level, it might help us
- 05:17better appreciate some of these
- 05:18other, social determinants of health.
- 05:20So my goals are to
- 05:22think about new ways of
- 05:23using quantitative measure to subtle
- 05:24social determinants of mental health,
- 05:26including transgenerational
- 05:27cultural persistence,
- 05:28an embodiment of these large
- 05:30scale forces of macroeconomic change,
- 05:32and then to leverage causal
- 05:33inference techniques from historical macroeconomics,
- 05:35economics,
- 05:36to hopefully begin to unlock,
- 05:38again, this hypothesis around the
- 05:40Eastland paradox and then identify
- 05:42particular risk and protective factors
- 05:45for particular mental health disorders.
- 05:46And again, I'll show you
- 05:47suggested evidence here. I'm not
- 05:48saying I'm I'm there by
- 05:49any means, but this is
- 05:50sort of where we're trying
- 05:51to go. So
- 05:54some of the motivation from
- 05:55this comes from, I think,
- 05:56a really interesting set of
- 05:58researching,
- 05:58cognitive psychology.
- 06:00Joe Henrich, who started as
- 06:01a trained as an anthropologist,
- 06:03taught in economics at University
- 06:04of British Columbia, is now
- 06:05the chair of psychology at
- 06:06Harvard,
- 06:07is famous for, you know,
- 06:09essentially finding instead of hypotheses
- 06:11around the weirdest people in
- 06:12the world. So WEIRD stands
- 06:14for Western, educated, industrialized,
- 06:16democratic.
- 06:17And essentially, it's a series
- 06:19of findings that says, hey,
- 06:20most of our cognitive,
- 06:22theories, and our even our
- 06:24our, neuroimaging evidence comes from
- 06:27fairly similar populations from a
- 06:28social learning perspective. And in
- 06:30fact, if you look at
- 06:31the ethnographic record, these societies
- 06:33are pretty unusual,
- 06:36in the following types of
- 06:38ways. So to focus on
- 06:39kinship for a second,
- 06:41having little or no marriage
- 06:43to cousins or other relatives.
- 06:44Most, you know,
- 06:46folks in what are called
- 06:47weird societies, we find this
- 06:48a little bit odd.
- 06:49Twenty five percent of societies
- 06:51share this property in the
- 06:52African African American, meaning, you
- 06:53know, seventy five percent don't.
- 06:55When we think about other
- 06:55things like monogamous marriage, nuclear
- 06:57families, and then you and
- 06:58local residents,
- 07:00you know, those of us
- 07:01that have ever thought about
- 07:02living with, relatives, etcetera, to
- 07:04save money, if there's some
- 07:06kind of taboo around that,
- 07:07again, it's pretty unusual that,
- 07:10the kind of social norm
- 07:11that,
- 07:12you know, new families, couples
- 07:14are are living outside the
- 07:15the household. So,
- 07:17if you add up,
- 07:18most,
- 07:19societies of the twelve hundred
- 07:20sixty five ethnographic atlas share
- 07:22zero of these five kinship
- 07:24features with,
- 07:25with weird societies, and almost
- 07:27none share all five.
- 07:30Henrik's hypothesis, which really extends
- 07:32work from the famous sociologist
- 07:33Max Weber, is, not only
- 07:36that the increasing market penetration
- 07:38has, you know, led to
- 07:39individualization,
- 07:40this is also sort of
- 07:41theory that Marx made famous.
- 07:43But that in particular, there
- 07:44are changes in the the
- 07:46middle ages that the, Catholic
- 07:48church and their institutions were
- 07:50somewhat intentionally trying to fracture
- 07:52kinship bonds into this particular
- 07:53package. So he goes through
- 07:54a whole theory about what
- 07:55their incentives were, why this
- 07:57happened, but does show pretty
- 07:58clear evidence that there was
- 07:59this structural change in kinship
- 08:02and that this has led
- 08:03us to a different,
- 08:05not just set of social
- 08:06norms this way, but, potentially
- 08:08could lead us to, interesting
- 08:11outcomes as I'll try to
- 08:11get to in a second.
- 08:12So
- 08:14that's where the framing the
- 08:15so the evidence comes from
- 08:16the ethnographic ATLAS and the,
- 08:18standard cross cultural survey, twelve
- 08:20hundred sixty five communities. And
- 08:22I'm gonna pull on the
- 08:23methodology of two very famous
- 08:25econ papers to, try to
- 08:27establish,
- 08:28these these results. So one,
- 08:29it's,
- 08:31written Jen Roles, Women in
- 08:32the Plow, which, these,
- 08:35leading development economists,
- 08:37are very interested in how,
- 08:39this you know, when when
- 08:40jobs are scarce, women
- 08:42men should have more right
- 08:43to a job than women.
- 08:44The variation was from three
- 08:45point six percent in Iceland
- 08:47and ninety nine percent Egypt.
- 08:49And they wanted to show
- 08:50that, some of these features
- 08:52of
- 08:53societies in ethnographical record could
- 08:55actually be predicted, in fact,
- 08:56show historical persistence in predicting
- 08:58these modern day social norms.
- 09:00So their approach is to
- 09:02link that data to the,
- 09:05Ethnologue Language Atlas, which is
- 09:07a Language Atlas of the
- 09:08world, can be linked to
- 09:09those different societies. And so
- 09:11here you can see how
- 09:11they link,
- 09:14societies at the plow versus
- 09:15those that didn't have the
- 09:16plow. The hypothesis in their
- 09:17paper was essentially,
- 09:18was goes to anthropologist Esther
- 09:20Boseroff, is that societies at
- 09:22the plow favored,
- 09:24upper body muscular strength and
- 09:25would lead to a higher
- 09:27level of gender segregation in
- 09:29economic roles. And so you
- 09:30see that both in the
- 09:31ethnographic atlas and then using
- 09:33this mapping, they're able to
- 09:34show that indeed a higher
- 09:36fraction of ancestry from traditional
- 09:37plow use communities is associated
- 09:40with higher labour force participation
- 09:42between
- 09:43two thousand, actually, sorry, more
- 09:45plow use is less, and
- 09:47then, other really key outcomes
- 09:49when we think about gender
- 09:49inequality, including share of women
- 09:51in political positions and pretty
- 09:53large average effect sizes.
- 09:54Sizes. And, again, so the
- 09:56economics focus a lot on
- 09:57is how to use causal
- 09:58inference when you can't randomize.
- 09:59Right? So obviously, it's a
- 10:01large scale historical process. So
- 10:02we use something called instrumental
- 10:04variables, which is really not
- 10:05it's a can do, you
- 10:06know, random assignment in in
- 10:07a randomized controlled trial, but
- 10:09we need some other,
- 10:11instrument. So here they use
- 10:14a geological instrument saying there's
- 10:16an environment that could lead
- 10:17to one crop versus another
- 10:19to to create this IV.
- 10:20So I'm just showing that
- 10:20I pull in this methodology
- 10:22and then another very famous
- 10:24experiment.
- 10:26This is one of my
- 10:28thesis advisors and
- 10:30recommenders, and these charts are
- 10:32from a very famous paper,
- 10:34which shows that the,
- 10:36what we want to consider
- 10:37this process of
- 10:38historical institutional change, which are
- 10:40very interested in sort of
- 10:41Westernization.
- 10:42These
- 10:44scholars showed that the death
- 10:46rate of colonial settlers
- 10:48related to the likelihood of,
- 10:52extractive institutions. That's the higher
- 10:53the death rate, the more
- 10:54likely extractive institutions were to
- 10:57be set up in, in
- 10:58European colonies, and then that
- 11:00also,
- 11:01predicts,
- 11:03income today. So it's called
- 11:04an instrumental variable, that log
- 11:05of settler mortality,
- 11:07that's how many,
- 11:09colonial social are dying, they're
- 11:10more more likely to set
- 11:11up these terribly extractive institutions.
- 11:13Obviously, intuition there, but this
- 11:15paper and these,
- 11:17like I showed this in
- 11:17the RTC seminar, these were
- 11:19the only two,
- 11:20graphs shown in the twenty
- 11:22twenty four Nobel Prize in
- 11:23Economics for exactly this work,
- 11:24which went to these three
- 11:25authors,
- 11:26since since that presentation. So
- 11:28I'm trying to extend essentially
- 11:29those two key econ papers
- 11:31into how we think about
- 11:32the global burden of mental
- 11:34health disorders. So I'm gonna
- 11:35look at, these,
- 11:37a set of controls that
- 11:38comes from the ethnographic record
- 11:39as well.
- 11:42To give just some preliminary
- 11:43evidence and suggestive, I think,
- 11:45of of this hypothesis,
- 11:48well-being and hunter gatherer interest
- 11:50rates. So the first thing
- 11:50to look at is societies
- 11:52that seem the least affected
- 11:53by these processes of cultural
- 11:55change. And,
- 11:56I think the first to
- 11:57report, and this was accepted
- 11:59as a single author
- 12:01poster at the APA for
- 12:02the summer,
- 12:03that
- 12:04a fraction of gathering predominant
- 12:06ancestry significantly, policy, predicts country
- 12:08level happiness,
- 12:10and that's robust to country
- 12:12level controls in a variety
- 12:14of historical controls as well.
- 12:16And, find someone looking at
- 12:18hunter hunting or gathering, predominant.
- 12:20Again, these are actually, like,
- 12:21quite strong effect sizes, especially
- 12:23when we map them up
- 12:23to, what we typically think
- 12:25about,
- 12:26GDP or or other predictors.
- 12:30I'm now gonna focus on
- 12:31a couple of disorders. I
- 12:32I don't find strong effects,
- 12:34first of all, in bipolar
- 12:35psychotic disorders, which might be,
- 12:37you could say a bit
- 12:38a bit more expected, but,
- 12:39part of the hypothesis here
- 12:40is that some of the
- 12:41changes in constricts rupture have
- 12:42led to increase in
- 12:44guilt based or internalizing disorders.
- 12:46So I'm gonna focus on
- 12:47substance use disorders and, self
- 12:50harm and suicide.
- 12:52So using the, Ace Moble
- 12:54Johnson and Robinson instrument from
- 12:55this, paper that just won
- 12:57the the Nobel, I find,
- 12:59that
- 13:01the expropriation risk, that's the
- 13:03stronger the democratic institutions, actually,
- 13:05the light more likely these,
- 13:07these, eusasors are. And then
- 13:09using their instrument of log
- 13:10settled mortality, I also find,
- 13:13in in the IV,
- 13:15that the higher the death
- 13:16rate of the coin, the
- 13:17slower the, lower the contemporary
- 13:20prevalence rate of of these
- 13:21disorders. The outcome, by the
- 13:22way, is the twenty nineteen
- 13:23global burden disease to sort
- 13:25of take out the effects
- 13:25of COVID.
- 13:28Also, again, suggesting that there's
- 13:30a strong cultural influence here
- 13:32is is that
- 13:34the colon colonizer style also
- 13:36really matters for the,
- 13:38prevalence of disorders.
- 13:39Conversely, if you look at
- 13:41some, you know, predictors of
- 13:42kinship in the ethnographic atlas,
- 13:44we can find different effects.
- 13:45So cousin marriage, again, a
- 13:46pretty strong,
- 13:48predictor of non weird kinship
- 13:50structure,
- 13:51is associated with lower rates
- 13:53of alcohol use disorders,
- 13:55versus monogamous marriage, which is
- 13:56assigned with with higher rates.
- 13:58I find very similar results
- 14:00when, looking at drug use
- 14:01disorders,
- 14:03both for institutions,
- 14:04you know, these, colonial institutions,
- 14:06again, increasing the the risk,
- 14:09and then, aggregate kinship score,
- 14:11again, a higher,
- 14:13average kinship score of
- 14:15ancestral
- 14:17groups in any country is
- 14:19associated with a lower level
- 14:20of substance use disorders today.
- 14:23And, again, a similar set
- 14:25of findings with opioid use
- 14:26disorder.
- 14:28Self harm, again,
- 14:30not as robust of results,
- 14:32but this is a a
- 14:33global burden disease aggregate of
- 14:35suicide and self injurious behavior
- 14:37and, again, democratic institutions, and
- 14:39this is and long term
- 14:40mortality,
- 14:41predicting
- 14:42in the expected directions that
- 14:44this sort of Westernization
- 14:46is leading, you know, is
- 14:47associated with, and if you
- 14:48take this as suggestive causal
- 14:50evidence,
- 14:51higher levels of these disorders.
- 14:56So that's sort of shifting,
- 14:57you know, and the hypothesis
- 14:59is, you know, maybe the,
- 15:02as these institutions came through,
- 15:03the fracturing of kinship networks
- 15:06and,
- 15:07the individualization
- 15:08that we see under,
- 15:10the kind of structures of
- 15:12of modern capitalism.
- 15:13They might be weeding the
- 15:14higher incomes but also putting
- 15:16us at risk of certain,
- 15:17disorders, both those that we
- 15:18can measure easily like this
- 15:20and other features, and the
- 15:21combination of those two factors
- 15:23is why we might see
- 15:24the
- 15:25Eastland paradox. But, again, I
- 15:26have a lot more due
- 15:27to work to do to
- 15:28get there.
- 15:29I'll just take one final
- 15:31bit to show how this
- 15:32methodology could be used to
- 15:33maybe better appreciate
- 15:35particular social risk factors for,
- 15:40for particular mental health disorders.
- 15:41So this is,
- 15:43been with my senior thesis
- 15:45advisor, Lal Caplan.
- 15:46The hypothesis here is that
- 15:48anorexia
- 15:49nervosa,
- 15:50might have lower rates of
- 15:52prevalence in matrilineal societies, which
- 15:54are societies in which,
- 15:56kin based lineages based on
- 15:57the mother's family, not the
- 15:58father's. They're typically associated with
- 16:00more political power in the
- 16:01hands of, of women and
- 16:03of female households. And, the
- 16:05the hypothesis essentially that, you
- 16:07know, there's been ethnographic evidence
- 16:08of less object
- 16:10divisation of female bodies, and
- 16:12that might lead to lower
- 16:13rates of prevalence.
- 16:15So indeed, we find that
- 16:18ancestral fraction of matrimonial kinship
- 16:20is associated with lower rates
- 16:22of eating disorders in both
- 16:24sexes and females as well.
- 16:25And then there's a very
- 16:27nice instrument
- 16:28in the economics literature, which
- 16:29is coral reef formation.
- 16:31There's a ethnographic work on
- 16:33the,
- 16:34density of coral reefs being,
- 16:36more likely to create, fishing
- 16:38communities, and we also know
- 16:39that fishing communities are more
- 16:40likely to be matrilineal. There's
- 16:42a sense of, when some
- 16:43folks are going out into
- 16:44the water, others are able
- 16:46to maintain more,
- 16:47control over the land,
- 16:49and and associations are important
- 16:50for politics, and that's increased
- 16:52the likelihood of formation of
- 16:54of matrilineal
- 16:55versus patrilineal societies. And so
- 16:57using that instrument,
- 16:59and if you take the
- 17:01exclusion restriction that the only
- 17:02way that this is affecting
- 17:04modern day eating disorders is
- 17:05through this channel, then that's
- 17:07gonna be an instrumental variable
- 17:08for,
- 17:10the effect of maternal kinship
- 17:11on
- 17:13modern eating disorders. Again, we
- 17:14find
- 17:15similarly sized effects that maternal
- 17:17kinship
- 17:18is is associated with
- 17:20lower prevalence of eating disorders
- 17:22in countries today. So,
- 17:25hopefully, you know, trying to
- 17:26establish some interesting findings on,
- 17:29using these techniques,
- 17:32of long duration history, to
- 17:34explain some of the prevalence
- 17:35of these mental health disorders,
- 17:36and,
- 17:37hopefully one day to
- 17:39actually identify
- 17:44so thank you very much
- 17:45for listening to this portion
- 17:47of the talk. And, again,
- 17:48I'm
- 17:48really just honored to, introduce
- 17:50one of my colleagues, Jay.
- 17:51You already heard from from
- 17:52doctor Crystal,
- 17:54this, you know, decade plus
- 17:56commitment to a place on
- 17:57the ground.
- 17:58Paul Farmer wrote one of
- 18:00his letters for, medical school.
- 18:01He was a mentor of
- 18:02mine. I know, you know,
- 18:03felt very highly about him
- 18:04and his work and where
- 18:05he would go, and he's
- 18:06been using these lessons,
- 18:09to to generate new understandings
- 18:10about mental health stigma in
- 18:12addition to being the chief
- 18:12resident in RTP. So,
- 18:15really happy to be a
- 18:16co resident with Jay and
- 18:17can't wait to hear what
- 18:18what he's gonna say.
- 18:25Alright.
- 18:26Thank you, Matt, for, the
- 18:28broad overview,
- 18:29and thanks for the introduction
- 18:31to,
- 18:32Jeff. Oh, yeah.
- 18:35So, today, I'm gonna be
- 18:36talking about, my work, in
- 18:39Uganda. And as, you know,
- 18:40Matt said, I've been working
- 18:41there for, ten years now.
- 18:43So I thought I'd start
- 18:45by, you know, talking a
- 18:46little bit about my personal
- 18:47story of, like, what brings
- 18:48me to this work.
- 18:50So the arrows on the
- 18:51map point to all the
- 18:51areas, all all the places
- 18:53that that I've lived in
- 18:54my life. So I've lived
- 18:55in, like, a lot of
- 18:55places.
- 18:56I was born in Seoul,
- 18:57South Korea. I lived there
- 18:59until I was nine. And
- 19:00then, I moved around a
- 19:01lot, like Hawaii, South Florida,
- 19:03Appalachia, parts of the deep
- 19:04south.
- 19:06And in a lot of
- 19:06the places that I grew
- 19:07up, I was the only
- 19:08Asian person.
- 19:10And,
- 19:11you know, and it's quite
- 19:13a peculiar thing being the
- 19:15only person that looks like
- 19:16you in a in a
- 19:18place, and it makes people,
- 19:19I feel like, kinda label
- 19:20you as that. And it's
- 19:22very difficult to get past
- 19:23that, in terms of, like,
- 19:24people, like, recognizing your identity,
- 19:27recognizing who you are, like,
- 19:28beyond your race. Right?
- 19:30So I I didn't really
- 19:31feel feel, like, accepted into
- 19:33the American community. I didn't
- 19:34really feel accepted into Korean
- 19:36community anymore because, you know,
- 19:37I was
- 19:38pretty acculturated in America as
- 19:40well. So,
- 19:42in some ways that my
- 19:43high school self couldn't articulate
- 19:45at the at the time,
- 19:46I felt
- 19:47like I didn't quite develop
- 19:48in the way that I
- 19:49wanted to in terms of
- 19:50my identity, in high school.
- 19:51So I wanted to take
- 19:53a year off before going
- 19:54to college to figure myself
- 19:56out,
- 19:56to see, you know, like,
- 19:58what's important to me of
- 19:59who I am, you know,
- 20:00all these kind of existential,
- 20:02types of questions.
- 20:04So, you know, I thought
- 20:05I knew eastern culture and
- 20:06western culture having lived in
- 20:07Korea and having lived in
- 20:09the US, but I wanted
- 20:10to go somewhere as different
- 20:11as possible to figure out,
- 20:13you know, my identity and
- 20:14what I wanted to do.
- 20:15So I thought, Africa was
- 20:17very different, and I looked
- 20:18for some English speaking countries
- 20:20in Africa. I and Ghana,
- 20:22seems to be, you know,
- 20:23the the place that, that
- 20:25that made sense. So I
- 20:26used money that I saved
- 20:27from high school. I wrote
- 20:28to my university to defer
- 20:29to a year.
- 20:31And then I told my
- 20:32parents that I'm not gonna
- 20:34go to college
- 20:36immediately, and they were very
- 20:37thrilled about that, obviously.
- 20:40And then, and then I
- 20:41went to Ghana.
- 20:43And,
- 20:44living in Ghana, you know,
- 20:45I stayed in this, like,
- 20:46small town. I traveled around
- 20:48for a bit, and then
- 20:48I stayed in this, like,
- 20:49small town. I tried to
- 20:50make a routine for myself.
- 20:51And I just tried to
- 20:52wanted to live like a
- 20:53normal person,
- 20:55you know, in this society,
- 20:57as much as that is
- 20:58possible. Right? So I ran
- 20:59in, like, a room. I
- 21:00had, like, mattress in the
- 21:01floor. And my friends were,
- 21:02you know, Ghanaian guys from,
- 21:04like, sixteen to twenty four
- 21:05years old. We, like, play
- 21:06barefoot soccer. We would like
- 21:07to wrestling contests.
- 21:09And we we would just
- 21:10hang out. Right? As, you
- 21:11know, you'd want and they
- 21:13were friends. And and I
- 21:15guess, say, in this process,
- 21:17it is also very striking
- 21:18the disparity in opportunity, disparity
- 21:20in health care.
- 21:22You know, multiple of my
- 21:23friends had family members died
- 21:24from preventable illnesses,
- 21:26and it just seems so
- 21:27unfair. Right? Like, the price
- 21:29of Starbucks coffee in the
- 21:31US in the right hands
- 21:32at the right time could
- 21:33literally save somebody's life.
- 21:36So I I thought this
- 21:37is so compelling,
- 21:39that
- 21:40and I thought the disparity
- 21:41in global
- 21:42I thought the global disparity
- 21:44was a global emergency.
- 21:47And, in the process of
- 21:48living in a different place,
- 21:49I also thought more about
- 21:50my identity, like, what that
- 21:52means. Like, do I have
- 21:52to be Korean? Do I
- 21:53have to be American? What
- 21:55does that mean to be
- 21:55American, or what does that
- 21:56mean to be Korean?
- 21:58So I embrace, like, more
- 21:59of an identity as a
- 22:00global citizen. And to me,
- 22:02that means that I care
- 22:03about all people regardless of
- 22:04where they're from, regardless of
- 22:06their race, and, regard and
- 22:08regardless of their background, that
- 22:09everybody deserves to be treated
- 22:11with the utmost dignity and
- 22:12respect.
- 22:14So in college, at Washington
- 22:16University, I I looked for
- 22:18opportunities
- 22:19to, to, you know, further
- 22:21my experience and further my
- 22:22skills.
- 22:23So,
- 22:24in college,
- 22:25so in my travels, you
- 22:26know, I saw that a
- 22:27lot of people use traditional
- 22:28medicines to treat different
- 22:30illnesses. And I thought this
- 22:31is very interesting because, malaria
- 22:33medication, artemisinin, was discovered from
- 22:35Chinese traditional medications. So I
- 22:37was wondering if, you know,
- 22:39ever anybody had studied African
- 22:40traditional
- 22:41traditional medications in the same
- 22:43way. So I emailed around
- 22:44in college, and, after about
- 22:46twenty cold emails, I found
- 22:47somebody at Oxford, in the
- 22:49UK that does some some
- 22:50research in traditional medicine, and
- 22:52he referred me to, some
- 22:54of some of his colleagues
- 22:55in Uganda.
- 22:55And then I went to
- 22:56Uganda.
- 22:58In in Uganda,
- 23:00during the course of the
- 23:01research analysis and journalism then,
- 23:03I just formed a lot
- 23:04of, like, really great relationships
- 23:05that still maintain today. So,
- 23:08the picture on the right
- 23:09is Peter Weiswe.
- 23:10You know, he's my, good
- 23:12mentor. He's,
- 23:14he he's on the the
- 23:15WHO advisory board from maternal
- 23:17health,
- 23:18and, you know, I've had
- 23:19a decade long relationship with
- 23:20them. And in the middle
- 23:22are, you know, Kazindu and
- 23:23Peter, who I've known for
- 23:25ten plus years that remain
- 23:26like good friends. We've seen
- 23:27each other through, you know,
- 23:29through through through life, through,
- 23:30like, marriage, through having kids.
- 23:32And, these relationships, as well
- 23:34as the work, was so
- 23:35compelling that it kept me
- 23:37coming back, year after year.
- 23:40And,
- 23:41in medical school,
- 23:43you know, at that point,
- 23:44I was doing several projects,
- 23:46you know, sending some
- 23:48American students from my, alma
- 23:49mater to go to Uganda
- 23:50to work on some projects.
- 23:52And in twenty eighteen, first
- 23:54year of medical school, medical
- 23:55school friend of mine donated
- 23:57forty thousand dollars, and we
- 23:58started, Empowered through Health, which
- 24:00is a five one c
- 24:01three organization.
- 24:03So our focus is in
- 24:04health care, research and education.
- 24:07So I'll talk briefly about
- 24:08that to kind of give
- 24:09you a background.
- 24:11So the purple district is
- 24:12where we work. It's called
- 24:13Brianda district. So Uganda is
- 24:15a low income country, but,
- 24:17you know, within Uganda, there's
- 24:18a lot of regional disparities
- 24:19as well. So, the area
- 24:21that we work is called
- 24:22the Busoga region. It's one
- 24:23of nine major regions in
- 24:24Uganda. It has approximately about
- 24:26four million
- 24:27people. It consistently has about
- 24:29the second worst health outcomes
- 24:30in Uganda out of all
- 24:31the regions.
- 24:33And when we were picking
- 24:34a site to really make
- 24:37a base for us, we
- 24:38wanted to go where the
- 24:39need was sacred where where
- 24:41there were the most gaps.
- 24:42So we need assessments. We
- 24:44did we did,
- 24:45consult we consulted with government
- 24:47officials, and, you know, we
- 24:48found a community that, you
- 24:49know, didn't really have
- 24:51very consistent access to modern,
- 24:53medical care.
- 24:56So, that's behind the district
- 24:57and then Tunde.
- 24:59So we started a health
- 25:00center,
- 25:01and since we started operating,
- 25:03we've provided care to over
- 25:04fifty thousand people, general medical
- 25:06care, like, maternal maternal care,
- 25:08mental health care.
- 25:10We have, like, collaborations with
- 25:11district for the,
- 25:13referral center for mental health
- 25:14for this whole district, and
- 25:16anecdotally, people from surrounding districts
- 25:18also come. So,
- 25:20I think our catchment area
- 25:21is even, like, you know,
- 25:23more than the district population.
- 25:26And we also run various
- 25:27public health interventions out of
- 25:29the health center.
- 25:31And we began providing psychiatric
- 25:32care in twenty twenty one,
- 25:34in partnership with the district
- 25:36where, you know, it's kinda
- 25:37like, okay. We don't have,
- 25:38like, psychiatric care. We we
- 25:40don't have any, any services
- 25:42available. So, you know, so
- 25:43we can, like, work together
- 25:44to, start this out of
- 25:46our health center.
- 25:48And in terms of education,
- 25:50you know, we do two
- 25:51things with education. One thing
- 25:53one one one,
- 25:54one, avenue is working with
- 25:56predoctoral students. So, like, MD
- 25:58students, master students, and undergraduate
- 26:00students,
- 26:01in both Uganda and America,
- 26:03and we do a simultaneous
- 26:05training model. So that's a
- 26:06global health experiential fellowship.
- 26:09We just recently,
- 26:10submitted an article to Global
- 26:11Health Science and Practice,
- 26:13about a review of this
- 26:14program that, some people in
- 26:16the department were a part
- 26:16of such as, doctor Rorba,
- 26:20over there.
- 26:21And,
- 26:22and, so so, basically, you
- 26:24know, through this simultaneous training
- 26:25model, which is like a
- 26:26five week in person experience,
- 26:28in Uganda,
- 26:30that has both Ugandan and
- 26:31American students, like, working together
- 26:33on research. We found significant
- 26:36increases in research in observable,
- 26:38measurable research skills, in the
- 26:40Ugandan students, and the quality
- 26:42of data was also very
- 26:43rich in terms of, like,
- 26:44what people got out of
- 26:44this experience. So it can
- 26:44be a
- 26:48so it's a new model
- 26:49of working together,
- 26:50of, like, global health, capacity
- 26:52building.
- 26:53And we also do, education
- 26:55in the community, which means,
- 26:57like, public health education, but
- 26:58we're also building a primary
- 26:59school, as well.
- 27:01And, you know, we do
- 27:02sensitization
- 27:03regarding,
- 27:04like, menstrual,
- 27:05menstrual dignity.
- 27:07We we make reusable pads
- 27:08to distribute them, work with
- 27:10schools to incorporate that into
- 27:11their tuitions too.
- 27:13So global health experiential fellowship
- 27:15has also been like a
- 27:17a very productive vehicle for
- 27:18research as well.
- 27:19So from, GHEF,
- 27:21from twenty twenty three, we
- 27:23have three peer reviewed publications
- 27:25published, three under reviews, I
- 27:26think two with minor revisions
- 27:28and one with major revision,
- 27:30and three more that we're
- 27:31about to submit. So it's
- 27:33become also very, productive as
- 27:35well.
- 27:36So our research,
- 27:37derives from our on the
- 27:39ground work. Right? So when
- 27:41we started psychiatric care,
- 27:43in twenty twenty one,
- 27:45at first, we were getting
- 27:46less than ten patients a
- 27:47month. And it's like,
- 27:49okay. You know, we are
- 27:50serving an area of, like,
- 27:51half a million people. Why
- 27:52why are we only getting,
- 27:53like, less than ten patients
- 27:54a month? Right? And this
- 27:55is an area that didn't
- 27:56really have access
- 27:57to the biomedical mental health
- 27:59care before. Right? And there's
- 28:00a lot of different,
- 28:02perceived etiologies of mental health
- 28:04and, you know, different people
- 28:05that people go to, like
- 28:06traditional healers and religious leaders.
- 28:08So we thought that the
- 28:09first step was to characterize
- 28:11and reduce, like, mental illness
- 28:12stigma and increase psychoeducation.
- 28:15So I'm gonna talk about
- 28:16that.
- 28:18So we've done some work
- 28:19characterizing mental illness stigma. So,
- 28:22you know, we use a
- 28:23vignette model to kind of,
- 28:24like, characterize
- 28:26what about mental illness is
- 28:27stigmatizing
- 28:28and,
- 28:29and, you know, what conditions
- 28:30might be most stigmatized.
- 28:32So we've done, some work
- 28:34on that. We've done some
- 28:35some,
- 28:36interpretive,
- 28:37phenomenological
- 28:38analysis on
- 28:40on, you know, theories of
- 28:41mental illness in Uganda as
- 28:43well.
- 28:44And we also have these,
- 28:45like, other works in progress
- 28:46that further characterizes mental illness
- 28:47stigma that, you know, we're
- 28:49hoping to publish within within
- 28:50a within a year that
- 28:51we already have data collected
- 28:53for.
- 28:53So I I'm just gonna
- 28:54give you give an example
- 28:55of a community based intervention
- 28:57that we conducted for mental
- 28:58illness stigma. So,
- 29:00so when we were starting
- 29:01psychiatric care, you know, as
- 29:03I said, you know, not
- 29:04many people are coming. Right?
- 29:05So we thought the first
- 29:06step was, you know, like
- 29:07a program.
- 29:08So what we did was
- 29:10we did some focus groups,
- 29:12to
- 29:13figure out, you know, what
- 29:15people think about, you know,
- 29:16current beliefs and attitudes for
- 29:17severe mental illnesses. So we
- 29:19have four focus group discussions.
- 29:21And from that, we need
- 29:22a list of criteria
- 29:24for a community play, and
- 29:26then we had an open
- 29:27come open competition with everybody
- 29:29in the community that could,
- 29:31you know, they could team
- 29:32up, and they could,
- 29:33and and they could, and
- 29:35and they could, you know,
- 29:36perform a play that met
- 29:37the criteria
- 29:38of destigmatizing mental illness.
- 29:41And,
- 29:42so
- 29:43we chose theater as a
- 29:44medium because it's a a
- 29:45common entertainment medium in rural
- 29:47Uganda.
- 29:48And so four teams competed,
- 29:49won one, and, you know,
- 29:50we had them tour some
- 29:52villages, and they won a
- 29:53monetary prize as well. So
- 29:55we evaluated the effectiveness of
- 29:56the intervention one weekend and
- 29:58one year one week
- 30:00after the intervention and one
- 30:01year in.
- 30:02So this is kinda like
- 30:03the flowchart for,
- 30:04for for for the study.
- 30:06So one hundred and one
- 30:07participants were administered in the
- 30:09initial questionnaire.
- 30:10Seventy seven that attended the
- 30:11initial theater intervention. Fifty seven
- 30:13of the seventy seven were
- 30:14administered a questionnaire one week
- 30:16later, and forty six of
- 30:17fifty seven were found one
- 30:19year later to, ask a
- 30:20questionnaire measuring mental illness stigma.
- 30:23So as you can see,
- 30:26acceptance for those with severe
- 30:28mental illness increased,
- 30:29pretty significantly. The effect size
- 30:31is about one point o,
- 30:32both in the one week
- 30:33follow-up and the one year
- 30:34follow-up as well.
- 30:36And, also, you know, more
- 30:38practically, the number of patients
- 30:40that we're seeing for severe
- 30:41mental illness in Uganda is
- 30:43now over one hundred a
- 30:44month as well. So, you
- 30:45know, although that's not you
- 30:47know, you can't really assume
- 30:49causality there, but, you know,
- 30:51it's
- 30:52you know, they're
- 30:54the it it it has
- 30:55helped in terms of, like,
- 30:56you know, providing more care
- 30:57to more people as well.
- 30:59And we also converted this
- 31:00to, like, a radio intervention
- 31:02too that, we,
- 31:03that we, published about too.
- 31:06So I submitted a k
- 31:07twenty three a few months
- 31:08ago on, you know, furthering
- 31:10the same. So, you know,
- 31:13so so so some of,
- 31:13like, research and, you know,
- 31:15we certainly have a lot
- 31:16of preliminary data on this.
- 31:17So research aim one is
- 31:19to just characterize the media,
- 31:21you know, preferences, like health
- 31:22information delivery networks, like what
- 31:24that's like in this patient.
- 31:26And aim two is to
- 31:27refine the intervention that we
- 31:29already have.
- 31:31Aim three is to assess
- 31:32the feasibility,
- 31:33acceptability, and preliminary efficacy of
- 31:35the intervention.
- 31:37So
- 31:37I have five different mentors
- 31:39from five different institutions,
- 31:40k, and two from Uganda
- 31:42and three from US, including,
- 31:44Robert Rosenheck at Yale. So
- 31:46these are some of the,
- 31:48expertise that I hope to
- 31:49gain.
- 31:50So
- 31:51I wanna be somebody that
- 31:52can develop interventions, community based
- 31:55interventions, and test the effectiveness
- 31:57of those interventions
- 31:58and scale it up. So
- 32:00I feel like the training
- 32:01that I'm getting in the
- 32:02k is setting the is
- 32:04setting a good stage,
- 32:05for my future,
- 32:07goals.
- 32:09And some of the other,
- 32:10things that, you know, I'm
- 32:11interested into is working with
- 32:13existing communities to improve care
- 32:15delivery as well. So we've
- 32:16we've done, you know, some
- 32:18preliminary work on the existing
- 32:21care delivery networks in Uganda
- 32:23and how we can work
- 32:24with them
- 32:25to, to provide better care.
- 32:27Right? So a lot of
- 32:28people so majority of people
- 32:29in rural Uganda, first go
- 32:31to religious leaders and traditional
- 32:33healers. Right?
- 32:34So we've done some work
- 32:35characterizing that as well as
- 32:37some, you know, some some,
- 32:39some
- 32:40some data on,
- 32:42willingness to collaborate among, like,
- 32:44religious leaders, traditional healers, and
- 32:46biomedical providers as well.
- 32:48So
- 32:50so we're,
- 32:51planning,
- 32:52a r thirty four submission
- 32:53in June.
- 32:55Initially, I was planning in
- 32:56October, but, you know, doctor
- 32:57Crystal pointed out that I
- 32:58can apply for it in
- 32:59June as a as a
- 33:01resident. So
- 33:03so, so so, basically, one
- 33:05intervention is, you know, this
- 33:07collaborative care model for severe
- 33:09mental illness,
- 33:10utilizing
- 33:11traditional healers, religious leaders, and
- 33:13biomedical providers.
- 33:14So researching one is develop
- 33:16a culturally tailored collaborative care
- 33:18model and two, evaluate the
- 33:20feasibility of that intervention.
- 33:23So,
- 33:24there has been, collaborative models
- 33:26for severe mental illness and
- 33:28LMICs. Like, Vikram Patel did
- 33:30one with late, community health
- 33:32providers, but not with, you
- 33:34know, traditional healers and religious
- 33:35leaders. We had graduated did
- 33:36one in Nigeria, but it
- 33:38was in the context of
- 33:39prayer camps. So prayer camps
- 33:40in West Africa are where
- 33:42hundreds of people with severe
- 33:43mental illness are all together,
- 33:44and that's a model that's
- 33:45pretty exclusive to West Africa
- 33:47only. So this is this
- 33:49this could be a template
- 33:50in how we work with
- 33:51with existing care systems
- 33:53in delivering care to severe
- 33:54mental illness, including in the
- 33:56United States.
- 33:58So
- 33:59and another r thirty four,
- 34:00that I have planned, I
- 34:01submitted a pilot grant to,
- 34:03Sierra,
- 34:05regarding this,
- 34:06is a client with care
- 34:07models for for depression. So,
- 34:09you know, group psychotherapy has
- 34:11been shown to be very
- 34:12effective in treating depression in
- 34:13LMI C settings.
- 34:15So, you know, why don't
- 34:16we train people that people
- 34:17already go for depression, like
- 34:18religious leaders, you know, traditional
- 34:20healers,
- 34:21and better the effectiveness?
- 34:23So those are, you know,
- 34:23some of the other, research
- 34:25aims too.
- 34:26And some potential directions that
- 34:28we haven't really, collected preliminary
- 34:30data for, but we're planning
- 34:31to this summer,
- 34:33is, the overlap between education
- 34:35and mental health.
- 34:37So school discontinuation is, like,
- 34:39a major issue,
- 34:40you know,
- 34:42in LMICs and in Uganda,
- 34:44in America too. But, you
- 34:45know,
- 34:47if you go to the
- 34:47school in Uganda,
- 34:49in the area that we
- 34:50work, so there's a lot
- 34:51of regional disparities as well.
- 34:53But, in first grade, there
- 34:54might be two hundred people
- 34:55enrolled. So there's, like, a
- 34:56roster at the school showing
- 34:57you how many people are
- 34:58enrolled in in each grade.
- 35:00So grade one, two hundred
- 35:01people. By the time you
- 35:02get to grade six, like,
- 35:03sixth grade, there's ten people.
- 35:05So school discontinuation is, like,
- 35:07a major issue.
- 35:09So and, you know, it's
- 35:10also I don't associated, like,
- 35:12as, like, a very traumatic
- 35:13experience for a lot of
- 35:14people,
- 35:16not being able to afford
- 35:17to continue going to school.
- 35:19So, like, what if you
- 35:20can combine a psychological and
- 35:22an economic intervention,
- 35:23creating a community mentorship system,
- 35:25a vocational training system in
- 35:27the community
- 35:28that, that
- 35:30that can, you know, empower
- 35:32people at, like, a very
- 35:33critical phase of their lives.
- 35:35So we're collecting some preliminary
- 35:37data for this this summer.
- 35:38So hopefully, this this can
- 35:39become another potential aim.
- 35:42So this is just generally
- 35:44my five year plan. For
- 35:45the sake of simplicity, I
- 35:46made a
- 35:48for the sake of simplicity
- 35:49simplicity, I made the assumption
- 35:50that it'll take each grant
- 35:51one resubmission to receive it.
- 35:54So, you know, several paths
- 35:55to, like, r ones and
- 35:56becoming an independent researcher. I'm
- 35:58also very interested in, taking
- 35:59some of the lessons, centered
- 36:01around community based interventions to
- 36:03the United States.
- 36:04For example, in in the
- 36:05elderly, in the United States,
- 36:07loneliness is a huge epidemic.
- 36:09So is, like, elderly, you
- 36:10know, a common mental illnesses
- 36:12as well. So and and
- 36:13treatment in America, I feel
- 36:15like a lot of times
- 36:16is very devoid of community
- 36:17aspects. So what if we
- 36:18can train activity managers at
- 36:20nursing homes too in providing
- 36:21group psychotherapy,
- 36:23right, and measure outcomes that
- 36:25way. So so some more
- 36:26directions that I'm interested in
- 36:28as well, domestically too.
- 36:32So we're gonna actually save
- 36:33questions until the end of
- 36:35the end of,
- 36:37our overall talk.
- 36:38But, you know, it's a
- 36:40pleasure to introduce,
- 36:41another
- 36:42one of my, colleagues, Marcus.
- 36:45He's been a he he's
- 36:46a chief resident of,
- 36:49of the residency,
- 36:50currently.
- 36:51He's a member of the
- 36:54Yaqui tribe in Arizona,
- 36:56and he's a leader in
- 36:57his community as well. And,
- 36:59you know, I I had
- 36:59the privilege of visiting him
- 37:01in Tucson,
- 37:02like, last month, and I
- 37:04saw how much
- 37:05how much he means and
- 37:06how much it means that,
- 37:07you know, he's achieved what
- 37:08he has achieved to this
- 37:09degree, to his community, to
- 37:10thousands of people in this
- 37:11community.
- 37:13And I think it's like
- 37:14and, you know, his plan
- 37:15is to go back to
- 37:15Arizona,
- 37:16work with his community, and,
- 37:18you know, empower his community,
- 37:20and better better mental health
- 37:21care. So,
- 37:23so it's an honor to
- 37:23be a co resident with
- 37:25you. And,
- 37:27yeah. And I'll Thanks for
- 37:28that, Dave.
- 37:33Well, good morning, everyone.
- 37:36For
- 37:37time purposes, I'll there will
- 37:39be some slides
- 37:40I skip and also because
- 37:41I just realized I gave
- 37:42Matt the wrong version,
- 37:44but it's mostly there. So
- 37:46we'll jump right into it.
- 37:47It it's kinda fitting. I
- 37:48I didn't I don't think
- 37:49we planned this, but the
- 37:50way we really started with,
- 37:52you know, Matt's, like, systems
- 37:53level
- 37:54kind of view, Jay at
- 37:56the country level, and then
- 37:57going further and further down,
- 37:58looking at the community level
- 38:00and at a much smaller
- 38:01scale of of what I've
- 38:02been doing. So
- 38:04I have been involved,
- 38:05with
- 38:07basically two projects longitudinally
- 38:09since I've been in residency
- 38:10related to, community health needs
- 38:13assessments and stigma reduction. So
- 38:15I'll be talking about two
- 38:16projects mostly because they they
- 38:18tie together.
- 38:19So the first thing I
- 38:20wanna jump in with, just
- 38:21to give you guys a
- 38:22backdrop of, like, who we're
- 38:22talking about. So as Jay
- 38:24mentioned,
- 38:24this is the Pascua Yaqui
- 38:26tribe. This is the tribe
- 38:27that I'm from.
- 38:28There is a unique setup
- 38:30here where the tribe is
- 38:31concentrated in the southwestern United
- 38:33States, both in the US
- 38:35and on the Mexican side
- 38:36of the border. Roughly ten
- 38:37thousand,
- 38:39enrolled members in the United
- 38:40States, another thirty thousand in
- 38:41Mexico.
- 38:42The largest clustering is our
- 38:44reservation in Southern Arizona where
- 38:46I'm from. It's just outside
- 38:47of Tucson.
- 38:48But we do have smaller
- 38:49metro community areas in Tucson
- 38:51and Phoenix,
- 38:52Central Arizona. There's also a
- 38:54small community in Texas and,
- 38:56Southern California,
- 38:58just to give you a
- 38:58backdrop of who this is.
- 39:01And the relevance. Relevance to
- 39:02global health. Native Americans occupy
- 39:04a really odd space in
- 39:05America because, you know, they're
- 39:07American citizens, but they often
- 39:09live in communities that are
- 39:10designated, you know, not entities
- 39:12of the United States. And
- 39:13because of that, there's a
- 39:14lot of different ideas around
- 39:15mental health, around, you know,
- 39:17how treatment is received in
- 39:18these communities.
- 39:20The other just pure relevance
- 39:21point from a psychiatric
- 39:23standpoint is, you know, Native
- 39:25Americans, if you look at
- 39:25health disparities
- 39:27for substance use,
- 39:28for trauma disorders,
- 39:29highest rate of any ethnic
- 39:31group, and it's really not
- 39:32close.
- 39:33There's also a really,
- 39:35you know,
- 39:36lot of research out there
- 39:37that talks about the completion
- 39:39of suicide in these communities
- 39:40being really just off the
- 39:41charts. And despite these
- 39:43depths of despair,
- 39:44very often, you know, there's
- 39:46not a lot of access
- 39:47to behavioral health centers and
- 39:48services, and really a lot
- 39:50of resistance for native communities
- 39:52to engage with Western medicine.
- 39:54And we'll talk a little
- 39:54bit about why.
- 39:57Don't just take my word
- 39:58for it. So this is
- 39:59from the CDC.
- 40:00This was released in twenty
- 40:01twenty one. This trend goes
- 40:03back much further than twenty
- 40:05fifteen.
- 40:06That top blue bar you
- 40:07see there is the, suicide
- 40:09completion rate by,
- 40:11Native Americans. And then that
- 40:13black bar there is the
- 40:15white population in the US.
- 40:16That dotted gray line is
- 40:18the US average. And then
- 40:19everyone else kinda clusters together.
- 40:21As you can see, one
- 40:22of the odd things, twenty
- 40:23nineteen, I guess not odd,
- 40:24not surprising. This disparity started
- 40:26to worsen a little bit.
- 40:27We think in response to
- 40:29the COVID nineteen pandemic,
- 40:31all minority populations saw a
- 40:33little bit of an increase
- 40:34around then.
- 40:36I like to include this
- 40:37just to give people a
- 40:38backdrop of what we're dealing
- 40:39with and also just show,
- 40:40you know, the disparity is
- 40:41pretty significant in these communities,
- 40:43particularly
- 40:44for native populations living in
- 40:46reservation communities.
- 40:49So what have we been
- 40:50doing about it? So back,
- 40:52in twenty twenty two, during
- 40:54my PGY2 year,
- 40:56I used my case rotation
- 40:59here at Yale, the, clinical
- 41:00and academic selective experience to
- 41:03basically work with my tribal
- 41:05health department
- 41:06on
- 41:07what was our first really
- 41:09broad
- 41:10community health needs assessments focused
- 41:11on behavioral health. And to
- 41:13do this with,
- 41:15basically to do this with
- 41:16validated scales and screening metrics,
- 41:18because we didn't have a
- 41:20lot of people utilizing behavioral
- 41:21healthcare services, unfortunately.
- 41:23Although we had a suspicion
- 41:24based on national trends that
- 41:25there should be a lot
- 41:26of this in the community.
- 41:28So we ended up getting
- 41:29a pretty good sample size.
- 41:30This was more than I'd
- 41:31ever been surveyed for behavioral
- 41:32health purposes in my community.
- 41:34Keep in mind, like I
- 41:35said, the reservation's roughly about
- 41:36five thousand ish people,
- 41:38but we were surveying people
- 41:39also in the surrounding,
- 41:41metro areas.
- 41:42So we ended up,
- 41:44having
- 41:45PHQ score on there, a
- 41:47PC five, an audit for
- 41:48alcohol use disorder screening.
- 41:50Not surprising.
- 41:51Some of the results per
- 41:53se as far as, like,
- 41:53what we were expecting was
- 41:54in line with you know,
- 41:55we know there's a high
- 41:56prevalence of trauma. We know
- 41:57there's a high prevalence
- 41:59of potentially PTSD,
- 42:01anxiety,
- 42:02substance use disorders.
- 42:04The thing that we were
- 42:05trying to kinda demonstrate was
- 42:06even people who were screening
- 42:07positive on these metrics were
- 42:10not reaching out for health
- 42:11care services, and even less
- 42:12were being seen. So, really,
- 42:14we're seeing almost nobody who's
- 42:16screening positive.
- 42:17And our question is why?
- 42:19What's going on? Why is
- 42:20nobody utilizing what's out there?
- 42:22Because the tribe does have
- 42:23a behavioral health department that
- 42:25has really expanded and has
- 42:26really, you know, tried to
- 42:27to bring in people to
- 42:29to receive treatment. But we
- 42:30got a lot of responses
- 42:31like this. So things talking
- 42:33about stigma, talking about
- 42:35concerns related to being judged.
- 42:37And, I mean, the other
- 42:38flavor we got from a
- 42:39lot of people in some
- 42:40of these qualitative feedbacks
- 42:42were related to people saying
- 42:43that's not a medical problem.
- 42:44I wouldn't go to someone
- 42:45for that. That's the family
- 42:46problem. That's a unit problem.
- 42:47That's a community problem. Why
- 42:49would I talk to my
- 42:50doctor about that?
- 42:51The other piece of it
- 42:52was there was, you know,
- 42:54we gleaned a lot of
- 42:56evidence
- 42:56suggesting
- 42:57there wasn't a lot of
- 42:59health literacy related to behavioral
- 43:01health and and frankly, just
- 43:02a lot of internalized stigma
- 43:03around it.
- 43:04So
- 43:05how I, you know, attempted
- 43:07to continue this project and
- 43:09continue,
- 43:11you know, addressing some of
- 43:12these disparities
- 43:13was through,
- 43:15I was fortunate to get
- 43:16some funding through the APA
- 43:18SAMHSA fellowship to,
- 43:20pilot a project that I
- 43:21call Project STAR, strengthening tribal
- 43:23awareness and resilience.
- 43:26Fun fact, for those of
- 43:27you who are interested in,
- 43:28like, Native American cosmology and
- 43:31origin stories, for a lot
- 43:32of Mesoamerican
- 43:33tribes in particular, they will
- 43:35refer to themselves as the
- 43:36people of the stars. You
- 43:37can look at it a
- 43:38bunch of different ways, but
- 43:39the cheeky name is kind
- 43:40of a nod to to
- 43:42that origin.
- 43:44So what were our objectives?
- 43:45What were we trying to
- 43:46do here?
- 43:47Number one, just community engagement.
- 43:48So we really wanted to
- 43:50bring the community in, educate
- 43:52community members about
- 43:53the
- 43:55about
- 43:56how, behavioral health is important
- 43:58and also do it in
- 43:59a culturally appropriate way. We
- 44:01wanted to open the dialogue
- 44:03and really just get community
- 44:04members, you know, out in
- 44:05the open talking about this
- 44:06and bringing in people with
- 44:08lived experience, which goes with
- 44:10our collaborative partnership. So with
- 44:11the grant, I was able
- 44:12to bring in speakers who,
- 44:14you know, we paid them
- 44:15whether they were,
- 44:17some were tribal members, some
- 44:18were involved just with the
- 44:20tribal health department and and
- 44:22the behavioral health department and,
- 44:23you know, doing work with
- 44:24the MAT clinic that we
- 44:25have there or, you know,
- 44:27as counselors.
- 44:28And
- 44:29the other piece of it
- 44:30was really compiling a list
- 44:32of resources and, and just
- 44:33kind of educating the masses,
- 44:35like, these are the services
- 44:36out there, this is something
- 44:37that medicine can help with,
- 44:38this is something that our
- 44:39services can help with, we
- 44:40need to start utilizing these
- 44:41and, and also there's an
- 44:43incorporation of alternative med practices
- 44:45for the tribe too. So
- 44:46we wanted to just let
- 44:47people know that you don't
- 44:48have to choose one or
- 44:48the other, there is a
- 44:49bridge that's available. And we're
- 44:50trying to increase that.
- 44:52So how we went about
- 44:53it.
- 44:55There is a community
- 44:57attitudes of mental illness scale.
- 44:59There's not a lot of
- 45:01great scales out there for
- 45:02assessing stigma. This one I've
- 45:03seen replicated in a lot
- 45:05of different languages and studies.
- 45:07Essentially, a higher score on
- 45:09that correlates with a more
- 45:10positive attitude towards mental illness.
- 45:12So we did this before,
- 45:14the project started. We gathered
- 45:15some demographic data. We ran
- 45:17a whole awareness campaign that
- 45:18went over the course
- 45:20of, really, actively about six
- 45:22months, but in terms of
- 45:23the planning and everything else,
- 45:24it's over the course of
- 45:25a year. And then the
- 45:26crux of our opening the
- 45:28dialogue, opening the conversation to
- 45:30the community were these town
- 45:31hall style events where, you
- 45:33know, I flew back periodically.
- 45:34We would have these broadcast
- 45:36on
- 45:37the tribe social media pages.
- 45:39They're still up on their
- 45:40Facebook live pages, and they
- 45:42save the videos and catalog
- 45:43them there.
- 45:44And we would have people
- 45:45who were
- 45:46experts in, you know, community
- 45:48mental health, native health, native
- 45:50well-being,
- 45:51people who were doing work
- 45:52in the community. They each
- 45:53had, like, a different topic
- 45:54and focus, which we'll we'll
- 45:55talk about. And then at
- 45:56the end of it all,
- 45:57basically, we repeated the the
- 45:59scale, and we were looking
- 46:01at attendees versus non attendees
- 46:03in person. A crude metric,
- 46:04but really more so just
- 46:05to kind of get people
- 46:07involved in this and see
- 46:08if this is something we
- 46:09should sustainably do moving forward.
- 46:12So I just wanna show
- 46:13you guys, like, what the
- 46:14scale is. It's a cool,
- 46:15nifty little tool, basically, that,
- 46:17you know, it scores it
- 46:18on a Likert style scale.
- 46:20And, the long form is
- 46:22forty questions.
- 46:24The short form, which has
- 46:25been validated and replicated against
- 46:27itself,
- 46:28is only twenty questions. So
- 46:29it's not really cumbersome from
- 46:31a time standpoint. It's pretty,
- 46:33oops, pretty easy to,
- 46:35go about it in that
- 46:36way.
- 46:39Whoops, sorry.
- 46:41Just to talk about like
- 46:42our community messaging and our
- 46:44meetings, what they look like.
- 46:45So,
- 46:46we have a
- 46:48pretty nifty,
- 46:51youth council who does a
- 46:52lot of social media messaging.
- 46:53And we really just ramped
- 46:55that up during, you know,
- 46:56the time of my project
- 46:57to bring awareness to things
- 46:59related to addiction, things related
- 47:00to behavioral health services.
- 47:03We also had a lot
- 47:04of these signs posted out
- 47:05in the community with tribal
- 47:07symbols, tribal language, numbers to
- 47:09crisis lines, numbers to alternative
- 47:11medicine, to Centered Spirit, which
- 47:12is the main behavioral health
- 47:14center there.
- 47:15Everybody I knew in the
- 47:16community, I made sure to
- 47:17give them multiple signs as
- 47:18we're at every gate, every
- 47:20door,
- 47:21the community wellness center, all
- 47:23over the place.
- 47:25But the crux of it,
- 47:26as I mentioned, were these
- 47:27events. So these mind matters
- 47:28town hall events, as I
- 47:29mentioned, we we broadcast them
- 47:31on Zoom. We had them
- 47:32on Facebook Live. The tribal
- 47:34media team was involved. And
- 47:35all of these people were
- 47:37either community members or people
- 47:38directly involved with health care
- 47:40for the tribe and, behavioral
- 47:42health.
- 47:43We had sessions focused on
- 47:44addiction,
- 47:45on youth resilience, on, trauma
- 47:47and resilience healing, which ended
- 47:49up being our most well
- 47:51attended in person and also
- 47:52just offline, like, by views
- 47:54and videos shared, session.
- 47:57The in person sessions, obviously,
- 47:59you know, we had food.
- 47:59We had, like, these speakers
- 48:01come in. They were paid
- 48:02for their time.
- 48:04The lived experience side of
- 48:05things, I can't underscore
- 48:07just because
- 48:08there was
- 48:09this gentleman up here, you
- 48:11know, talked about his journey.
- 48:13Oops, sorry. Back.
- 48:17Whites.
- 48:18Whoops, sorry.
- 48:21One of these gentlemen's here
- 48:23was, part of the, the
- 48:24tribal methadone program and talked
- 48:25about, you know, his time
- 48:27and, and how recovery does
- 48:29happen. Really just giving people
- 48:30voice and hope. And it's
- 48:32something that means a lot
- 48:33more when it's coming from
- 48:34someone, you know, essentially.
- 48:36Really well attended
- 48:38our,
- 48:39viewership
- 48:40for
- 48:41the most popular video we
- 48:42had online was like fifteen
- 48:44thousand or something. So we
- 48:45had, I mean, we got
- 48:46to a pretty big audience
- 48:47considering this was shared beyond
- 48:49just, you know, our tribal
- 48:50community, but other tribal communities
- 48:52in Arizona who are interested
- 48:53in the model and interested
- 48:54in kind of how to
- 48:55get the word out about
- 48:56these services.
- 48:58I'll talk about outcomes. There's
- 49:00some typos on this next
- 49:02slide.
- 49:03You know, effectively, what we
- 49:04were able to show and
- 49:05see was there is at
- 49:07least in the short term,
- 49:08some change related to attitudes,
- 49:10stigmatizing attitudes towards mental illness.
- 49:12So unsurprisingly,
- 49:14people who,
- 49:16showed up in person pre
- 49:18any of this exposure, pre
- 49:19any of the
- 49:20teachings or psychoeducation, they already
- 49:22had a higher score. They
- 49:24were already less stigmatizing on
- 49:25mental health, but that makes
- 49:26sense because they're interested in
- 49:27this. But But even for
- 49:29that group, we were able
- 49:30to see a mild increase.
- 49:32The biggest increase we saw
- 49:33was actually for people who
- 49:34didn't attend anything in person.
- 49:35So whether that was them
- 49:37attending via just online, seeing
- 49:39the messaging in the community.
- 49:40We have a a nifty
- 49:42little app called Nixle where
- 49:43I can basically news blast
- 49:45and give people announcements about
- 49:46ongoings in the tribe at
- 49:48any time. So it gives
- 49:49me the ears of, like,
- 49:49five thousand people.
- 49:51Whether it's just that, whether
- 49:53it was just hearing from
- 49:54word-of-mouth,
- 49:55there's some changes
- 49:56effectively. We're trying to replicate
- 49:58this and see kind of
- 49:59similar to Jay's project if
- 50:00there's longitudinal results at six
- 50:02months at one year, which
- 50:03will happen this year.
- 50:05Qualitatively,
- 50:07we did have quite a
- 50:08bit
- 50:09of resource guides that came
- 50:11out of this. And just
- 50:12also, we, you know, had
- 50:13like QR codes and things
- 50:15that are sent out to
- 50:15people just as reminders. Like
- 50:17this is where you find
- 50:18all the services, even if
- 50:19you're not going within the
- 50:20tribe, but some people are
- 50:21reluctant to because they don't
- 50:22want to run into people
- 50:23they know.
- 50:24This is where you find
- 50:25services in Tucson or, you
- 50:27know, Southern Arizona type thing.
- 50:29For scalability,
- 50:31so I'm part of a
- 50:33center through the University of
- 50:34Arizona that recently formed focus
- 50:36on native American health.
- 50:38This center, right now has
- 50:40partnerships with multiple tribes in
- 50:42the Four Corners region, some
- 50:43in the Midwest now.
- 50:45They're interested in this project.
- 50:46We're trying to figure out
- 50:47a way to scale it
- 50:48so that we can have
- 50:49a similar model and a
- 50:50curriculum built where tribes who
- 50:52are kind of in the
- 50:53process of developing their behavioral
- 50:55health centers and really ramping
- 50:56up services and connection can
- 50:57start,
- 50:59with something at least. Some
- 51:00kind of way to to
- 51:01know that we're we're addressing
- 51:02stigma, we're addressing service underutilization.
- 51:07Just to give some acknowledgements
- 51:09to to these folks. So,
- 51:11our medical director, doctor Renteria,
- 51:13this dude,
- 51:14been with the tribe for
- 51:15a long time. He,
- 51:17was my primary care doc
- 51:19growing up.
- 51:20He's been super involved with
- 51:22a lot of efforts. He's
- 51:23approaching retirement, which I worry
- 51:25about.
- 51:27Our tribal health department has
- 51:28partnered with me for a
- 51:29number of endeavors, and we
- 51:30have a great working relationship
- 51:32as well as with our
- 51:33tribal council and obviously
- 51:35APA SAMHSA for putting the
- 51:36bill for this specifically.
- 51:39And then one last shameless
- 51:40plug. So upcoming next month,
- 51:42the Global Health Group will
- 51:44have one of our seminar
- 51:45series speakers, Doctor. Maval, coming
- 51:47in to talk about his
- 51:48work in, building bridges across
- 51:50the globe, developing joint collaboration,
- 51:53and interprofessional
- 51:54addiction education.
- 51:58I know we're ahead of
- 51:59time or maybe right on
- 52:00time, but I didn't wanna
- 52:01leave a chance for questions
- 52:03for everyone because I know
- 52:04we kind of deferred
- 52:06till the end. So if
- 52:07you guys wanna