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Yale Psychiatry Grand Rounds: "Frontiers in Global Mental Health Research & Service Delivery"

January 31, 2025

January 31, 2025

"Frontiers in Global Mental Health Research & Service Delivery"

Matthew Basilico, MD, PhD; Yang Jae Lee, MD; Marcos Moreno, MD, fourth-year residents, Yale Department of Psychiatry

ID
12697

Transcript

  • 00:01Hi. Well, thank you very
  • 00:02much, doctor Crystal. Oh, sorry.
  • 00:05Well, thank you very much,
  • 00:06doctor Crystal, for the generous
  • 00:08introduction.
  • 00:09So, you know, mental illnesses
  • 00:11are the leading,
  • 00:13leading cause of disability adjusted
  • 00:15life years globally. So I
  • 00:17think it's very appropriate that,
  • 00:18you know, we're having a
  • 00:20a grand rounds in global
  • 00:21mental health. So before further
  • 00:23ado, I wanna introduce,
  • 00:25my colleague and co resident,
  • 00:26Natje
  • 00:27Basilica, who comes to this
  • 00:29residency program with a lot
  • 00:30of accomplishments.
  • 00:32Before his career in medicine,
  • 00:34he was the chief of
  • 00:36staff for the president of
  • 00:37the World Bank, Jim Jim
  • 00:38Kim, chief of staff for
  • 00:40Paul Farmer. And when I
  • 00:41was an undergrad, I actually
  • 00:42read a book that he
  • 00:44wrote,
  • 00:46for my introduction to global
  • 00:47health course.
  • 00:49And he got his MD
  • 00:50PhD from Harvard in economics,
  • 00:53and, is, is honored to
  • 00:55have him as a colleague.
  • 00:56He was also recently voted
  • 00:57favorite professor at Harvard by
  • 00:59class of twenty twenty five.
  • 01:00So he somehow manages to,
  • 01:02you know, keep,
  • 01:04you know, his teaching responsibilities
  • 01:06as well as, you know,
  • 01:08being a being an outstanding
  • 01:09clinician here. So, before further
  • 01:11ado, here's Matt.
  • 01:17Thanks so much, Jay. True
  • 01:19honor to be up here
  • 01:20to speak to every one
  • 01:21of you.
  • 01:22And, you know, thank you
  • 01:23for making this forum where
  • 01:24we can explore some, you
  • 01:25know, key progress in in
  • 01:26this field. So I'll just
  • 01:28frame global mental health a
  • 01:30little bit.
  • 01:31The field,
  • 01:32which is, like, a part
  • 01:33of the the field of
  • 01:34global health is all about
  • 01:35inequity. Right? Inequity in, the
  • 01:38burden of illness, as Jim
  • 01:39mentioned, and equity
  • 01:41in access to services.
  • 01:42And so, I'm gonna focus
  • 01:44a bit of my talk
  • 01:45on some of these, on
  • 01:46the social determinants of health,
  • 01:47some of this unequal burden,
  • 01:49but really wanna emphasize and
  • 01:51and as as doctor Kristol
  • 01:52mentioned that,
  • 01:53you know, the the pioneers
  • 01:55in our field, but we
  • 01:55can say global health or
  • 01:57global mental health, have this,
  • 01:59you know, unique set of
  • 02:00characteristics
  • 02:01where they have worked in
  • 02:02partnership often for decades and
  • 02:04decades,
  • 02:05with some, communities in, tremendous
  • 02:08need of
  • 02:11of, from a health care
  • 02:11standpoint. And so I have
  • 02:13Paul Farmer up here who's
  • 02:14really sort of a pioneer
  • 02:15who who works and built
  • 02:17organizations in nine different countries.
  • 02:18They're working very tightly with
  • 02:20communities, and those lessons from
  • 02:22on the ground delivery problems
  • 02:24are then shared globally,
  • 02:26through many political changes,
  • 02:28like those that we're going
  • 02:28through now and, you know,
  • 02:29develop resilient health care delivery,
  • 02:32infrastructure
  • 02:33and lessons that can be,
  • 02:34you know, learned through the,
  • 02:36to the whole world. And
  • 02:37so Vikram Patel, they're our
  • 02:39good friends, but, you know,
  • 02:40Vikram is probably the biggest
  • 02:41name now in global mental
  • 02:42health, was also a psychiatrist
  • 02:44in his native
  • 02:45India for over twenty years
  • 02:46and then used those lessons
  • 02:48to become one of the,
  • 02:49you know, highest funded, researchers
  • 02:50in this area and really
  • 02:51a global thought leader bringing
  • 02:53these lessons of equity. And
  • 02:54I would just point out
  • 02:54that I think our next
  • 02:55two speakers, both Jay and
  • 02:57Marco, has really kind of
  • 02:58lived this archetypal model where
  • 03:00you're looking for sustained,
  • 03:02knowledge generation at the frontier,
  • 03:05working with communities in partnership,
  • 03:07and then asking how those
  • 03:08lessons can translate to,
  • 03:10improving, global mental health equity.
  • 03:12It's really, exciting to to
  • 03:14have been to co resident
  • 03:15with them, and and I
  • 03:15can't wait to see where
  • 03:17their work will go.
  • 03:19I'll just talk a little
  • 03:20bit about my,
  • 03:22my work in economics right
  • 03:23here,
  • 03:24some interesting findings,
  • 03:26from from tools that we
  • 03:27use in our discipline that
  • 03:29might, have relevance to the
  • 03:30ways that we think about,
  • 03:31the unequal distribution of mental
  • 03:33health disorders globally.
  • 03:35And, you know, so kind
  • 03:36of to take a recent
  • 03:37review, this is from, World
  • 03:38Psychiatry in twenty twenty four,
  • 03:40a great review, really emphasizing
  • 03:42that we know that adverse,
  • 03:44you know, social conditions, especially,
  • 03:47from anywhere from in utero
  • 03:48to, early childhood to adulthood,
  • 03:51obviously,
  • 03:53affect risk of a variety
  • 03:54of mental health disorders.
  • 03:57My teaching kind of straddles
  • 03:59two fields. One is, development
  • 04:01and global health, and the
  • 04:02other, this is kind of
  • 04:03the first lecture class of
  • 04:05kind of devoted to mental
  • 04:06health at a we think
  • 04:07at a top Egon department,
  • 04:08so trying to fuse these
  • 04:10two disciplines together.
  • 04:11And one of the kind
  • 04:12of interesting things that we
  • 04:13encounter is that
  • 04:15unlike the rest
  • 04:16of global health where we
  • 04:17have what's called the Preston
  • 04:18curve and health naturally gets
  • 04:21or, you know, it tends
  • 04:22to get better as country
  • 04:23incomes improve, We have kind
  • 04:25of the opposite,
  • 04:27finding in,
  • 04:29in, you know, subjective well-being.
  • 04:31And you may have seen
  • 04:32this on the front page
  • 04:34New York Times obituary
  • 04:35this month for Richard Easterlin,
  • 04:37who
  • 04:38found the very famous Easterlin
  • 04:40paradox, which is that despite
  • 04:41rapid growth in,
  • 04:44many countries, we don't see
  • 04:45a concomitant rise in well-being.
  • 04:48And so this has been
  • 04:50thought to be one of
  • 04:50the biggest puzzles in macroeconomics.
  • 04:52Why does why does economic
  • 04:56increase in subjective well-being? And
  • 04:57here's just a few examples
  • 04:58of this of this chart.
  • 04:59And as you you'll see
  • 05:00my hypothesis that I'm trying
  • 05:02to get at is that,
  • 05:04there's a there's a lot
  • 05:05going on here in the
  • 05:06aggregate social changes happening. This
  • 05:08is not just about income
  • 05:09changes. It's about other changes
  • 05:10in society,
  • 05:11sometimes very subtle changes. And
  • 05:13if we can better characterize
  • 05:14those, especially on a quantitative
  • 05:16level, it might help us
  • 05:17better appreciate some of these
  • 05:18other, social determinants of health.
  • 05:20So my goals are to
  • 05:22think about new ways of
  • 05:23using quantitative measure to subtle
  • 05:24social determinants of mental health,
  • 05:26including transgenerational
  • 05:27cultural persistence,
  • 05:28an embodiment of these large
  • 05:30scale forces of macroeconomic change,
  • 05:32and then to leverage causal
  • 05:33inference techniques from historical macroeconomics,
  • 05:35economics,
  • 05:36to hopefully begin to unlock,
  • 05:38again, this hypothesis around the
  • 05:40Eastland paradox and then identify
  • 05:42particular risk and protective factors
  • 05:45for particular mental health disorders.
  • 05:46And again, I'll show you
  • 05:47suggested evidence here. I'm not
  • 05:48saying I'm I'm there by
  • 05:49any means, but this is
  • 05:50sort of where we're trying
  • 05:51to go. So
  • 05:54some of the motivation from
  • 05:55this comes from, I think,
  • 05:56a really interesting set of
  • 05:58researching,
  • 05:58cognitive psychology.
  • 06:00Joe Henrich, who started as
  • 06:01a trained as an anthropologist,
  • 06:03taught in economics at University
  • 06:04of British Columbia, is now
  • 06:05the chair of psychology at
  • 06:06Harvard,
  • 06:07is famous for, you know,
  • 06:09essentially finding instead of hypotheses
  • 06:11around the weirdest people in
  • 06:12the world. So WEIRD stands
  • 06:14for Western, educated, industrialized,
  • 06:16democratic.
  • 06:17And essentially, it's a series
  • 06:19of findings that says, hey,
  • 06:20most of our cognitive,
  • 06:22theories, and our even our
  • 06:24our, neuroimaging evidence comes from
  • 06:27fairly similar populations from a
  • 06:28social learning perspective. And in
  • 06:30fact, if you look at
  • 06:31the ethnographic record, these societies
  • 06:33are pretty unusual,
  • 06:36in the following types of
  • 06:38ways. So to focus on
  • 06:39kinship for a second,
  • 06:41having little or no marriage
  • 06:43to cousins or other relatives.
  • 06:44Most, you know,
  • 06:46folks in what are called
  • 06:47weird societies, we find this
  • 06:48a little bit odd.
  • 06:49Twenty five percent of societies
  • 06:51share this property in the
  • 06:52African African American, meaning, you
  • 06:53know, seventy five percent don't.
  • 06:55When we think about other
  • 06:55things like monogamous marriage, nuclear
  • 06:57families, and then you and
  • 06:58local residents,
  • 07:00you know, those of us
  • 07:01that have ever thought about
  • 07:02living with, relatives, etcetera, to
  • 07:04save money, if there's some
  • 07:06kind of taboo around that,
  • 07:07again, it's pretty unusual that,
  • 07:10the kind of social norm
  • 07:11that,
  • 07:12you know, new families, couples
  • 07:14are are living outside the
  • 07:15the household. So,
  • 07:17if you add up,
  • 07:18most,
  • 07:19societies of the twelve hundred
  • 07:20sixty five ethnographic atlas share
  • 07:22zero of these five kinship
  • 07:24features with,
  • 07:25with weird societies, and almost
  • 07:27none share all five.
  • 07:30Henrik's hypothesis, which really extends
  • 07:32work from the famous sociologist
  • 07:33Max Weber, is, not only
  • 07:36that the increasing market penetration
  • 07:38has, you know, led to
  • 07:39individualization,
  • 07:40this is also sort of
  • 07:41theory that Marx made famous.
  • 07:43But that in particular, there
  • 07:44are changes in the the
  • 07:46middle ages that the, Catholic
  • 07:48church and their institutions were
  • 07:50somewhat intentionally trying to fracture
  • 07:52kinship bonds into this particular
  • 07:53package. So he goes through
  • 07:54a whole theory about what
  • 07:55their incentives were, why this
  • 07:57happened, but does show pretty
  • 07:58clear evidence that there was
  • 07:59this structural change in kinship
  • 08:02and that this has led
  • 08:03us to a different,
  • 08:05not just set of social
  • 08:06norms this way, but, potentially
  • 08:08could lead us to, interesting
  • 08:11outcomes as I'll try to
  • 08:11get to in a second.
  • 08:12So
  • 08:14that's where the framing the
  • 08:15so the evidence comes from
  • 08:16the ethnographic ATLAS and the,
  • 08:18standard cross cultural survey, twelve
  • 08:20hundred sixty five communities. And
  • 08:22I'm gonna pull on the
  • 08:23methodology of two very famous
  • 08:25econ papers to, try to
  • 08:27establish,
  • 08:28these these results. So one,
  • 08:29it's,
  • 08:31written Jen Roles, Women in
  • 08:32the Plow, which, these,
  • 08:35leading development economists,
  • 08:37are very interested in how,
  • 08:39this you know, when when
  • 08:40jobs are scarce, women
  • 08:42men should have more right
  • 08:43to a job than women.
  • 08:44The variation was from three
  • 08:45point six percent in Iceland
  • 08:47and ninety nine percent Egypt.
  • 08:49And they wanted to show
  • 08:50that, some of these features
  • 08:52of
  • 08:53societies in ethnographical record could
  • 08:55actually be predicted, in fact,
  • 08:56show historical persistence in predicting
  • 08:58these modern day social norms.
  • 09:00So their approach is to
  • 09:02link that data to the,
  • 09:05Ethnologue Language Atlas, which is
  • 09:07a Language Atlas of the
  • 09:08world, can be linked to
  • 09:09those different societies. And so
  • 09:11here you can see how
  • 09:11they link,
  • 09:14societies at the plow versus
  • 09:15those that didn't have the
  • 09:16plow. The hypothesis in their
  • 09:17paper was essentially,
  • 09:18was goes to anthropologist Esther
  • 09:20Boseroff, is that societies at
  • 09:22the plow favored,
  • 09:24upper body muscular strength and
  • 09:25would lead to a higher
  • 09:27level of gender segregation in
  • 09:29economic roles. And so you
  • 09:30see that both in the
  • 09:31ethnographic atlas and then using
  • 09:33this mapping, they're able to
  • 09:34show that indeed a higher
  • 09:36fraction of ancestry from traditional
  • 09:37plow use communities is associated
  • 09:40with higher labour force participation
  • 09:42between
  • 09:43two thousand, actually, sorry, more
  • 09:45plow use is less, and
  • 09:47then, other really key outcomes
  • 09:49when we think about gender
  • 09:49inequality, including share of women
  • 09:51in political positions and pretty
  • 09:53large average effect sizes.
  • 09:54Sizes. And, again, so the
  • 09:56economics focus a lot on
  • 09:57is how to use causal
  • 09:58inference when you can't randomize.
  • 09:59Right? So obviously, it's a
  • 10:01large scale historical process. So
  • 10:02we use something called instrumental
  • 10:04variables, which is really not
  • 10:05it's a can do, you
  • 10:06know, random assignment in in
  • 10:07a randomized controlled trial, but
  • 10:09we need some other,
  • 10:11instrument. So here they use
  • 10:14a geological instrument saying there's
  • 10:16an environment that could lead
  • 10:17to one crop versus another
  • 10:19to to create this IV.
  • 10:20So I'm just showing that
  • 10:20I pull in this methodology
  • 10:22and then another very famous
  • 10:24experiment.
  • 10:26This is one of my
  • 10:28thesis advisors and
  • 10:30recommenders, and these charts are
  • 10:32from a very famous paper,
  • 10:34which shows that the,
  • 10:36what we want to consider
  • 10:37this process of
  • 10:38historical institutional change, which are
  • 10:40very interested in sort of
  • 10:41Westernization.
  • 10:42These
  • 10:44scholars showed that the death
  • 10:46rate of colonial settlers
  • 10:48related to the likelihood of,
  • 10:52extractive institutions. That's the higher
  • 10:53the death rate, the more
  • 10:54likely extractive institutions were to
  • 10:57be set up in, in
  • 10:58European colonies, and then that
  • 11:00also,
  • 11:01predicts,
  • 11:03income today. So it's called
  • 11:04an instrumental variable, that log
  • 11:05of settler mortality,
  • 11:07that's how many,
  • 11:09colonial social are dying, they're
  • 11:10more more likely to set
  • 11:11up these terribly extractive institutions.
  • 11:13Obviously, intuition there, but this
  • 11:15paper and these,
  • 11:17like I showed this in
  • 11:17the RTC seminar, these were
  • 11:19the only two,
  • 11:20graphs shown in the twenty
  • 11:22twenty four Nobel Prize in
  • 11:23Economics for exactly this work,
  • 11:24which went to these three
  • 11:25authors,
  • 11:26since since that presentation. So
  • 11:28I'm trying to extend essentially
  • 11:29those two key econ papers
  • 11:31into how we think about
  • 11:32the global burden of mental
  • 11:34health disorders. So I'm gonna
  • 11:35look at, these,
  • 11:37a set of controls that
  • 11:38comes from the ethnographic record
  • 11:39as well.
  • 11:42To give just some preliminary
  • 11:43evidence and suggestive, I think,
  • 11:45of of this hypothesis,
  • 11:48well-being and hunter gatherer interest
  • 11:50rates. So the first thing
  • 11:50to look at is societies
  • 11:52that seem the least affected
  • 11:53by these processes of cultural
  • 11:55change. And,
  • 11:56I think the first to
  • 11:57report, and this was accepted
  • 11:59as a single author
  • 12:01poster at the APA for
  • 12:02the summer,
  • 12:03that
  • 12:04a fraction of gathering predominant
  • 12:06ancestry significantly, policy, predicts country
  • 12:08level happiness,
  • 12:10and that's robust to country
  • 12:12level controls in a variety
  • 12:14of historical controls as well.
  • 12:16And, find someone looking at
  • 12:18hunter hunting or gathering, predominant.
  • 12:20Again, these are actually, like,
  • 12:21quite strong effect sizes, especially
  • 12:23when we map them up
  • 12:23to, what we typically think
  • 12:25about,
  • 12:26GDP or or other predictors.
  • 12:30I'm now gonna focus on
  • 12:31a couple of disorders. I
  • 12:32I don't find strong effects,
  • 12:34first of all, in bipolar
  • 12:35psychotic disorders, which might be,
  • 12:37you could say a bit
  • 12:38a bit more expected, but,
  • 12:39part of the hypothesis here
  • 12:40is that some of the
  • 12:41changes in constricts rupture have
  • 12:42led to increase in
  • 12:44guilt based or internalizing disorders.
  • 12:46So I'm gonna focus on
  • 12:47substance use disorders and, self
  • 12:50harm and suicide.
  • 12:52So using the, Ace Moble
  • 12:54Johnson and Robinson instrument from
  • 12:55this, paper that just won
  • 12:57the the Nobel, I find,
  • 12:59that
  • 13:01the expropriation risk, that's the
  • 13:03stronger the democratic institutions, actually,
  • 13:05the light more likely these,
  • 13:07these, eusasors are. And then
  • 13:09using their instrument of log
  • 13:10settled mortality, I also find,
  • 13:13in in the IV,
  • 13:15that the higher the death
  • 13:16rate of the coin, the
  • 13:17slower the, lower the contemporary
  • 13:20prevalence rate of of these
  • 13:21disorders. The outcome, by the
  • 13:22way, is the twenty nineteen
  • 13:23global burden disease to sort
  • 13:25of take out the effects
  • 13:25of COVID.
  • 13:28Also, again, suggesting that there's
  • 13:30a strong cultural influence here
  • 13:32is is that
  • 13:34the colon colonizer style also
  • 13:36really matters for the,
  • 13:38prevalence of disorders.
  • 13:39Conversely, if you look at
  • 13:41some, you know, predictors of
  • 13:42kinship in the ethnographic atlas,
  • 13:44we can find different effects.
  • 13:45So cousin marriage, again, a
  • 13:46pretty strong,
  • 13:48predictor of non weird kinship
  • 13:50structure,
  • 13:51is associated with lower rates
  • 13:53of alcohol use disorders,
  • 13:55versus monogamous marriage, which is
  • 13:56assigned with with higher rates.
  • 13:58I find very similar results
  • 14:00when, looking at drug use
  • 14:01disorders,
  • 14:03both for institutions,
  • 14:04you know, these, colonial institutions,
  • 14:06again, increasing the the risk,
  • 14:09and then, aggregate kinship score,
  • 14:11again, a higher,
  • 14:13average kinship score of
  • 14:15ancestral
  • 14:17groups in any country is
  • 14:19associated with a lower level
  • 14:20of substance use disorders today.
  • 14:23And, again, a similar set
  • 14:25of findings with opioid use
  • 14:26disorder.
  • 14:28Self harm, again,
  • 14:30not as robust of results,
  • 14:32but this is a a
  • 14:33global burden disease aggregate of
  • 14:35suicide and self injurious behavior
  • 14:37and, again, democratic institutions, and
  • 14:39this is and long term
  • 14:40mortality,
  • 14:41predicting
  • 14:42in the expected directions that
  • 14:44this sort of Westernization
  • 14:46is leading, you know, is
  • 14:47associated with, and if you
  • 14:48take this as suggestive causal
  • 14:50evidence,
  • 14:51higher levels of these disorders.
  • 14:56So that's sort of shifting,
  • 14:57you know, and the hypothesis
  • 14:59is, you know, maybe the,
  • 15:02as these institutions came through,
  • 15:03the fracturing of kinship networks
  • 15:06and,
  • 15:07the individualization
  • 15:08that we see under,
  • 15:10the kind of structures of
  • 15:12of modern capitalism.
  • 15:13They might be weeding the
  • 15:14higher incomes but also putting
  • 15:16us at risk of certain,
  • 15:17disorders, both those that we
  • 15:18can measure easily like this
  • 15:20and other features, and the
  • 15:21combination of those two factors
  • 15:23is why we might see
  • 15:24the
  • 15:25Eastland paradox. But, again, I
  • 15:26have a lot more due
  • 15:27to work to do to
  • 15:28get there.
  • 15:29I'll just take one final
  • 15:31bit to show how this
  • 15:32methodology could be used to
  • 15:33maybe better appreciate
  • 15:35particular social risk factors for,
  • 15:40for particular mental health disorders.
  • 15:41So this is,
  • 15:43been with my senior thesis
  • 15:45advisor, Lal Caplan.
  • 15:46The hypothesis here is that
  • 15:48anorexia
  • 15:49nervosa,
  • 15:50might have lower rates of
  • 15:52prevalence in matrilineal societies, which
  • 15:54are societies in which,
  • 15:56kin based lineages based on
  • 15:57the mother's family, not the
  • 15:58father's. They're typically associated with
  • 16:00more political power in the
  • 16:01hands of, of women and
  • 16:03of female households. And, the
  • 16:05the hypothesis essentially that, you
  • 16:07know, there's been ethnographic evidence
  • 16:08of less object
  • 16:10divisation of female bodies, and
  • 16:12that might lead to lower
  • 16:13rates of prevalence.
  • 16:15So indeed, we find that
  • 16:18ancestral fraction of matrimonial kinship
  • 16:20is associated with lower rates
  • 16:22of eating disorders in both
  • 16:24sexes and females as well.
  • 16:25And then there's a very
  • 16:27nice instrument
  • 16:28in the economics literature, which
  • 16:29is coral reef formation.
  • 16:31There's a ethnographic work on
  • 16:33the,
  • 16:34density of coral reefs being,
  • 16:36more likely to create, fishing
  • 16:38communities, and we also know
  • 16:39that fishing communities are more
  • 16:40likely to be matrilineal. There's
  • 16:42a sense of, when some
  • 16:43folks are going out into
  • 16:44the water, others are able
  • 16:46to maintain more,
  • 16:47control over the land,
  • 16:49and and associations are important
  • 16:50for politics, and that's increased
  • 16:52the likelihood of formation of
  • 16:54of matrilineal
  • 16:55versus patrilineal societies. And so
  • 16:57using that instrument,
  • 16:59and if you take the
  • 17:01exclusion restriction that the only
  • 17:02way that this is affecting
  • 17:04modern day eating disorders is
  • 17:05through this channel, then that's
  • 17:07gonna be an instrumental variable
  • 17:08for,
  • 17:10the effect of maternal kinship
  • 17:11on
  • 17:13modern eating disorders. Again, we
  • 17:14find
  • 17:15similarly sized effects that maternal
  • 17:17kinship
  • 17:18is is associated with
  • 17:20lower prevalence of eating disorders
  • 17:22in countries today. So,
  • 17:25hopefully, you know, trying to
  • 17:26establish some interesting findings on,
  • 17:29using these techniques,
  • 17:32of long duration history, to
  • 17:34explain some of the prevalence
  • 17:35of these mental health disorders,
  • 17:36and,
  • 17:37hopefully one day to
  • 17:39actually identify
  • 17:44so thank you very much
  • 17:45for listening to this portion
  • 17:47of the talk. And, again,
  • 17:48I'm
  • 17:48really just honored to, introduce
  • 17:50one of my colleagues, Jay.
  • 17:51You already heard from from
  • 17:52doctor Crystal,
  • 17:54this, you know, decade plus
  • 17:56commitment to a place on
  • 17:57the ground.
  • 17:58Paul Farmer wrote one of
  • 18:00his letters for, medical school.
  • 18:01He was a mentor of
  • 18:02mine. I know, you know,
  • 18:03felt very highly about him
  • 18:04and his work and where
  • 18:05he would go, and he's
  • 18:06been using these lessons,
  • 18:09to to generate new understandings
  • 18:10about mental health stigma in
  • 18:12addition to being the chief
  • 18:12resident in RTP. So,
  • 18:15really happy to be a
  • 18:16co resident with Jay and
  • 18:17can't wait to hear what
  • 18:18what he's gonna say.
  • 18:25Alright.
  • 18:26Thank you, Matt, for, the
  • 18:28broad overview,
  • 18:29and thanks for the introduction
  • 18:31to,
  • 18:32Jeff. Oh, yeah.
  • 18:35So, today, I'm gonna be
  • 18:36talking about, my work, in
  • 18:39Uganda. And as, you know,
  • 18:40Matt said, I've been working
  • 18:41there for, ten years now.
  • 18:43So I thought I'd start
  • 18:45by, you know, talking a
  • 18:46little bit about my personal
  • 18:47story of, like, what brings
  • 18:48me to this work.
  • 18:50So the arrows on the
  • 18:51map point to all the
  • 18:51areas, all all the places
  • 18:53that that I've lived in
  • 18:54my life. So I've lived
  • 18:55in, like, a lot of
  • 18:55places.
  • 18:56I was born in Seoul,
  • 18:57South Korea. I lived there
  • 18:59until I was nine. And
  • 19:00then, I moved around a
  • 19:01lot, like Hawaii, South Florida,
  • 19:03Appalachia, parts of the deep
  • 19:04south.
  • 19:06And in a lot of
  • 19:06the places that I grew
  • 19:07up, I was the only
  • 19:08Asian person.
  • 19:10And,
  • 19:11you know, and it's quite
  • 19:13a peculiar thing being the
  • 19:15only person that looks like
  • 19:16you in a in a
  • 19:18place, and it makes people,
  • 19:19I feel like, kinda label
  • 19:20you as that. And it's
  • 19:22very difficult to get past
  • 19:23that, in terms of, like,
  • 19:24people, like, recognizing your identity,
  • 19:27recognizing who you are, like,
  • 19:28beyond your race. Right?
  • 19:30So I I didn't really
  • 19:31feel feel, like, accepted into
  • 19:33the American community. I didn't
  • 19:34really feel accepted into Korean
  • 19:36community anymore because, you know,
  • 19:37I was
  • 19:38pretty acculturated in America as
  • 19:40well. So,
  • 19:42in some ways that my
  • 19:43high school self couldn't articulate
  • 19:45at the at the time,
  • 19:46I felt
  • 19:47like I didn't quite develop
  • 19:48in the way that I
  • 19:49wanted to in terms of
  • 19:50my identity, in high school.
  • 19:51So I wanted to take
  • 19:53a year off before going
  • 19:54to college to figure myself
  • 19:56out,
  • 19:56to see, you know, like,
  • 19:58what's important to me of
  • 19:59who I am, you know,
  • 20:00all these kind of existential,
  • 20:02types of questions.
  • 20:04So, you know, I thought
  • 20:05I knew eastern culture and
  • 20:06western culture having lived in
  • 20:07Korea and having lived in
  • 20:09the US, but I wanted
  • 20:10to go somewhere as different
  • 20:11as possible to figure out,
  • 20:13you know, my identity and
  • 20:14what I wanted to do.
  • 20:15So I thought, Africa was
  • 20:17very different, and I looked
  • 20:18for some English speaking countries
  • 20:20in Africa. I and Ghana,
  • 20:22seems to be, you know,
  • 20:23the the place that, that
  • 20:25that made sense. So I
  • 20:26used money that I saved
  • 20:27from high school. I wrote
  • 20:28to my university to defer
  • 20:29to a year.
  • 20:31And then I told my
  • 20:32parents that I'm not gonna
  • 20:34go to college
  • 20:36immediately, and they were very
  • 20:37thrilled about that, obviously.
  • 20:40And then, and then I
  • 20:41went to Ghana.
  • 20:43And,
  • 20:44living in Ghana, you know,
  • 20:45I stayed in this, like,
  • 20:46small town. I traveled around
  • 20:48for a bit, and then
  • 20:48I stayed in this, like,
  • 20:49small town. I tried to
  • 20:50make a routine for myself.
  • 20:51And I just tried to
  • 20:52wanted to live like a
  • 20:53normal person,
  • 20:55you know, in this society,
  • 20:57as much as that is
  • 20:58possible. Right? So I ran
  • 20:59in, like, a room. I
  • 21:00had, like, mattress in the
  • 21:01floor. And my friends were,
  • 21:02you know, Ghanaian guys from,
  • 21:04like, sixteen to twenty four
  • 21:05years old. We, like, play
  • 21:06barefoot soccer. We would like
  • 21:07to wrestling contests.
  • 21:09And we we would just
  • 21:10hang out. Right? As, you
  • 21:11know, you'd want and they
  • 21:13were friends. And and I
  • 21:15guess, say, in this process,
  • 21:17it is also very striking
  • 21:18the disparity in opportunity, disparity
  • 21:20in health care.
  • 21:22You know, multiple of my
  • 21:23friends had family members died
  • 21:24from preventable illnesses,
  • 21:26and it just seems so
  • 21:27unfair. Right? Like, the price
  • 21:29of Starbucks coffee in the
  • 21:31US in the right hands
  • 21:32at the right time could
  • 21:33literally save somebody's life.
  • 21:36So I I thought this
  • 21:37is so compelling,
  • 21:39that
  • 21:40and I thought the disparity
  • 21:41in global
  • 21:42I thought the global disparity
  • 21:44was a global emergency.
  • 21:47And, in the process of
  • 21:48living in a different place,
  • 21:49I also thought more about
  • 21:50my identity, like, what that
  • 21:52means. Like, do I have
  • 21:52to be Korean? Do I
  • 21:53have to be American? What
  • 21:55does that mean to be
  • 21:55American, or what does that
  • 21:56mean to be Korean?
  • 21:58So I embrace, like, more
  • 21:59of an identity as a
  • 22:00global citizen. And to me,
  • 22:02that means that I care
  • 22:03about all people regardless of
  • 22:04where they're from, regardless of
  • 22:06their race, and, regard and
  • 22:08regardless of their background, that
  • 22:09everybody deserves to be treated
  • 22:11with the utmost dignity and
  • 22:12respect.
  • 22:14So in college, at Washington
  • 22:16University, I I looked for
  • 22:18opportunities
  • 22:19to, to, you know, further
  • 22:21my experience and further my
  • 22:22skills.
  • 22:23So,
  • 22:24in college,
  • 22:25so in my travels, you
  • 22:26know, I saw that a
  • 22:27lot of people use traditional
  • 22:28medicines to treat different
  • 22:30illnesses. And I thought this
  • 22:31is very interesting because, malaria
  • 22:33medication, artemisinin, was discovered from
  • 22:35Chinese traditional medications. So I
  • 22:37was wondering if, you know,
  • 22:39ever anybody had studied African
  • 22:40traditional
  • 22:41traditional medications in the same
  • 22:43way. So I emailed around
  • 22:44in college, and, after about
  • 22:46twenty cold emails, I found
  • 22:47somebody at Oxford, in the
  • 22:49UK that does some some
  • 22:50research in traditional medicine, and
  • 22:52he referred me to, some
  • 22:54of some of his colleagues
  • 22:55in Uganda.
  • 22:55And then I went to
  • 22:56Uganda.
  • 22:58In in Uganda,
  • 23:00during the course of the
  • 23:01research analysis and journalism then,
  • 23:03I just formed a lot
  • 23:04of, like, really great relationships
  • 23:05that still maintain today. So,
  • 23:08the picture on the right
  • 23:09is Peter Weiswe.
  • 23:10You know, he's my, good
  • 23:12mentor. He's,
  • 23:14he he's on the the
  • 23:15WHO advisory board from maternal
  • 23:17health,
  • 23:18and, you know, I've had
  • 23:19a decade long relationship with
  • 23:20them. And in the middle
  • 23:22are, you know, Kazindu and
  • 23:23Peter, who I've known for
  • 23:25ten plus years that remain
  • 23:26like good friends. We've seen
  • 23:27each other through, you know,
  • 23:29through through through life, through,
  • 23:30like, marriage, through having kids.
  • 23:32And, these relationships, as well
  • 23:34as the work, was so
  • 23:35compelling that it kept me
  • 23:37coming back, year after year.
  • 23:40And,
  • 23:41in medical school,
  • 23:43you know, at that point,
  • 23:44I was doing several projects,
  • 23:46you know, sending some
  • 23:48American students from my, alma
  • 23:49mater to go to Uganda
  • 23:50to work on some projects.
  • 23:52And in twenty eighteen, first
  • 23:54year of medical school, medical
  • 23:55school friend of mine donated
  • 23:57forty thousand dollars, and we
  • 23:58started, Empowered through Health, which
  • 24:00is a five one c
  • 24:01three organization.
  • 24:03So our focus is in
  • 24:04health care, research and education.
  • 24:07So I'll talk briefly about
  • 24:08that to kind of give
  • 24:09you a background.
  • 24:11So the purple district is
  • 24:12where we work. It's called
  • 24:13Brianda district. So Uganda is
  • 24:15a low income country, but,
  • 24:17you know, within Uganda, there's
  • 24:18a lot of regional disparities
  • 24:19as well. So, the area
  • 24:21that we work is called
  • 24:22the Busoga region. It's one
  • 24:23of nine major regions in
  • 24:24Uganda. It has approximately about
  • 24:26four million
  • 24:27people. It consistently has about
  • 24:29the second worst health outcomes
  • 24:30in Uganda out of all
  • 24:31the regions.
  • 24:33And when we were picking
  • 24:34a site to really make
  • 24:37a base for us, we
  • 24:38wanted to go where the
  • 24:39need was sacred where where
  • 24:41there were the most gaps.
  • 24:42So we need assessments. We
  • 24:44did we did,
  • 24:45consult we consulted with government
  • 24:47officials, and, you know, we
  • 24:48found a community that, you
  • 24:49know, didn't really have
  • 24:51very consistent access to modern,
  • 24:53medical care.
  • 24:56So, that's behind the district
  • 24:57and then Tunde.
  • 24:59So we started a health
  • 25:00center,
  • 25:01and since we started operating,
  • 25:03we've provided care to over
  • 25:04fifty thousand people, general medical
  • 25:06care, like, maternal maternal care,
  • 25:08mental health care.
  • 25:10We have, like, collaborations with
  • 25:11district for the,
  • 25:13referral center for mental health
  • 25:14for this whole district, and
  • 25:16anecdotally, people from surrounding districts
  • 25:18also come. So,
  • 25:20I think our catchment area
  • 25:21is even, like, you know,
  • 25:23more than the district population.
  • 25:26And we also run various
  • 25:27public health interventions out of
  • 25:29the health center.
  • 25:31And we began providing psychiatric
  • 25:32care in twenty twenty one,
  • 25:34in partnership with the district
  • 25:36where, you know, it's kinda
  • 25:37like, okay. We don't have,
  • 25:38like, psychiatric care. We we
  • 25:40don't have any, any services
  • 25:42available. So, you know, so
  • 25:43we can, like, work together
  • 25:44to, start this out of
  • 25:46our health center.
  • 25:48And in terms of education,
  • 25:50you know, we do two
  • 25:51things with education. One thing
  • 25:53one one one,
  • 25:54one, avenue is working with
  • 25:56predoctoral students. So, like, MD
  • 25:58students, master students, and undergraduate
  • 26:00students,
  • 26:01in both Uganda and America,
  • 26:03and we do a simultaneous
  • 26:05training model. So that's a
  • 26:06global health experiential fellowship.
  • 26:09We just recently,
  • 26:10submitted an article to Global
  • 26:11Health Science and Practice,
  • 26:13about a review of this
  • 26:14program that, some people in
  • 26:16the department were a part
  • 26:16of such as, doctor Rorba,
  • 26:20over there.
  • 26:21And,
  • 26:22and, so so, basically, you
  • 26:24know, through this simultaneous training
  • 26:25model, which is like a
  • 26:26five week in person experience,
  • 26:28in Uganda,
  • 26:30that has both Ugandan and
  • 26:31American students, like, working together
  • 26:33on research. We found significant
  • 26:36increases in research in observable,
  • 26:38measurable research skills, in the
  • 26:40Ugandan students, and the quality
  • 26:42of data was also very
  • 26:43rich in terms of, like,
  • 26:44what people got out of
  • 26:44this experience. So it can
  • 26:44be a
  • 26:48so it's a new model
  • 26:49of working together,
  • 26:50of, like, global health, capacity
  • 26:52building.
  • 26:53And we also do, education
  • 26:55in the community, which means,
  • 26:57like, public health education, but
  • 26:58we're also building a primary
  • 26:59school, as well.
  • 27:01And, you know, we do
  • 27:02sensitization
  • 27:03regarding,
  • 27:04like, menstrual,
  • 27:05menstrual dignity.
  • 27:07We we make reusable pads
  • 27:08to distribute them, work with
  • 27:10schools to incorporate that into
  • 27:11their tuitions too.
  • 27:13So global health experiential fellowship
  • 27:15has also been like a
  • 27:17a very productive vehicle for
  • 27:18research as well.
  • 27:19So from, GHEF,
  • 27:21from twenty twenty three, we
  • 27:23have three peer reviewed publications
  • 27:25published, three under reviews, I
  • 27:26think two with minor revisions
  • 27:28and one with major revision,
  • 27:30and three more that we're
  • 27:31about to submit. So it's
  • 27:33become also very, productive as
  • 27:35well.
  • 27:36So our research,
  • 27:37derives from our on the
  • 27:39ground work. Right? So when
  • 27:41we started psychiatric care,
  • 27:43in twenty twenty one,
  • 27:45at first, we were getting
  • 27:46less than ten patients a
  • 27:47month. And it's like,
  • 27:49okay. You know, we are
  • 27:50serving an area of, like,
  • 27:51half a million people. Why
  • 27:52why are we only getting,
  • 27:53like, less than ten patients
  • 27:54a month? Right? And this
  • 27:55is an area that didn't
  • 27:56really have access
  • 27:57to the biomedical mental health
  • 27:59care before. Right? And there's
  • 28:00a lot of different,
  • 28:02perceived etiologies of mental health
  • 28:04and, you know, different people
  • 28:05that people go to, like
  • 28:06traditional healers and religious leaders.
  • 28:08So we thought that the
  • 28:09first step was to characterize
  • 28:11and reduce, like, mental illness
  • 28:12stigma and increase psychoeducation.
  • 28:15So I'm gonna talk about
  • 28:16that.
  • 28:18So we've done some work
  • 28:19characterizing mental illness stigma. So,
  • 28:22you know, we use a
  • 28:23vignette model to kind of,
  • 28:24like, characterize
  • 28:26what about mental illness is
  • 28:27stigmatizing
  • 28:28and,
  • 28:29and, you know, what conditions
  • 28:30might be most stigmatized.
  • 28:32So we've done, some work
  • 28:34on that. We've done some
  • 28:35some,
  • 28:36interpretive,
  • 28:37phenomenological
  • 28:38analysis on
  • 28:40on, you know, theories of
  • 28:41mental illness in Uganda as
  • 28:43well.
  • 28:44And we also have these,
  • 28:45like, other works in progress
  • 28:46that further characterizes mental illness
  • 28:47stigma that, you know, we're
  • 28:49hoping to publish within within
  • 28:50a within a year that
  • 28:51we already have data collected
  • 28:53for.
  • 28:53So I I'm just gonna
  • 28:54give you give an example
  • 28:55of a community based intervention
  • 28:57that we conducted for mental
  • 28:58illness stigma. So,
  • 29:00so when we were starting
  • 29:01psychiatric care, you know, as
  • 29:03I said, you know, not
  • 29:04many people are coming. Right?
  • 29:05So we thought the first
  • 29:06step was, you know, like
  • 29:07a program.
  • 29:08So what we did was
  • 29:10we did some focus groups,
  • 29:12to
  • 29:13figure out, you know, what
  • 29:15people think about, you know,
  • 29:16current beliefs and attitudes for
  • 29:17severe mental illnesses. So we
  • 29:19have four focus group discussions.
  • 29:21And from that, we need
  • 29:22a list of criteria
  • 29:24for a community play, and
  • 29:26then we had an open
  • 29:27come open competition with everybody
  • 29:29in the community that could,
  • 29:31you know, they could team
  • 29:32up, and they could,
  • 29:33and and they could, and
  • 29:35and they could, you know,
  • 29:36perform a play that met
  • 29:37the criteria
  • 29:38of destigmatizing mental illness.
  • 29:41And,
  • 29:42so
  • 29:43we chose theater as a
  • 29:44medium because it's a a
  • 29:45common entertainment medium in rural
  • 29:47Uganda.
  • 29:48And so four teams competed,
  • 29:49won one, and, you know,
  • 29:50we had them tour some
  • 29:52villages, and they won a
  • 29:53monetary prize as well. So
  • 29:55we evaluated the effectiveness of
  • 29:56the intervention one weekend and
  • 29:58one year one week
  • 30:00after the intervention and one
  • 30:01year in.
  • 30:02So this is kinda like
  • 30:03the flowchart for,
  • 30:04for for for the study.
  • 30:06So one hundred and one
  • 30:07participants were administered in the
  • 30:09initial questionnaire.
  • 30:10Seventy seven that attended the
  • 30:11initial theater intervention. Fifty seven
  • 30:13of the seventy seven were
  • 30:14administered a questionnaire one week
  • 30:16later, and forty six of
  • 30:17fifty seven were found one
  • 30:19year later to, ask a
  • 30:20questionnaire measuring mental illness stigma.
  • 30:23So as you can see,
  • 30:26acceptance for those with severe
  • 30:28mental illness increased,
  • 30:29pretty significantly. The effect size
  • 30:31is about one point o,
  • 30:32both in the one week
  • 30:33follow-up and the one year
  • 30:34follow-up as well.
  • 30:36And, also, you know, more
  • 30:38practically, the number of patients
  • 30:40that we're seeing for severe
  • 30:41mental illness in Uganda is
  • 30:43now over one hundred a
  • 30:44month as well. So, you
  • 30:45know, although that's not you
  • 30:47know, you can't really assume
  • 30:49causality there, but, you know,
  • 30:51it's
  • 30:52you know, they're
  • 30:54the it it it has
  • 30:55helped in terms of, like,
  • 30:56you know, providing more care
  • 30:57to more people as well.
  • 30:59And we also converted this
  • 31:00to, like, a radio intervention
  • 31:02too that, we,
  • 31:03that we, published about too.
  • 31:06So I submitted a k
  • 31:07twenty three a few months
  • 31:08ago on, you know, furthering
  • 31:10the same. So, you know,
  • 31:13so so so some of,
  • 31:13like, research and, you know,
  • 31:15we certainly have a lot
  • 31:16of preliminary data on this.
  • 31:17So research aim one is
  • 31:19to just characterize the media,
  • 31:21you know, preferences, like health
  • 31:22information delivery networks, like what
  • 31:24that's like in this patient.
  • 31:26And aim two is to
  • 31:27refine the intervention that we
  • 31:29already have.
  • 31:31Aim three is to assess
  • 31:32the feasibility,
  • 31:33acceptability, and preliminary efficacy of
  • 31:35the intervention.
  • 31:37So
  • 31:37I have five different mentors
  • 31:39from five different institutions,
  • 31:40k, and two from Uganda
  • 31:42and three from US, including,
  • 31:44Robert Rosenheck at Yale. So
  • 31:46these are some of the,
  • 31:48expertise that I hope to
  • 31:49gain.
  • 31:50So
  • 31:51I wanna be somebody that
  • 31:52can develop interventions, community based
  • 31:55interventions, and test the effectiveness
  • 31:57of those interventions
  • 31:58and scale it up. So
  • 32:00I feel like the training
  • 32:01that I'm getting in the
  • 32:02k is setting the is
  • 32:04setting a good stage,
  • 32:05for my future,
  • 32:07goals.
  • 32:09And some of the other,
  • 32:10things that, you know, I'm
  • 32:11interested into is working with
  • 32:13existing communities to improve care
  • 32:15delivery as well. So we've
  • 32:16we've done, you know, some
  • 32:18preliminary work on the existing
  • 32:21care delivery networks in Uganda
  • 32:23and how we can work
  • 32:24with them
  • 32:25to, to provide better care.
  • 32:27Right? So a lot of
  • 32:28people so majority of people
  • 32:29in rural Uganda, first go
  • 32:31to religious leaders and traditional
  • 32:33healers. Right?
  • 32:34So we've done some work
  • 32:35characterizing that as well as
  • 32:37some, you know, some some,
  • 32:39some
  • 32:40some data on,
  • 32:42willingness to collaborate among, like,
  • 32:44religious leaders, traditional healers, and
  • 32:46biomedical providers as well.
  • 32:48So
  • 32:50so we're,
  • 32:51planning,
  • 32:52a r thirty four submission
  • 32:53in June.
  • 32:55Initially, I was planning in
  • 32:56October, but, you know, doctor
  • 32:57Crystal pointed out that I
  • 32:58can apply for it in
  • 32:59June as a as a
  • 33:01resident. So
  • 33:03so, so so, basically, one
  • 33:05intervention is, you know, this
  • 33:07collaborative care model for severe
  • 33:09mental illness,
  • 33:10utilizing
  • 33:11traditional healers, religious leaders, and
  • 33:13biomedical providers.
  • 33:14So researching one is develop
  • 33:16a culturally tailored collaborative care
  • 33:18model and two, evaluate the
  • 33:20feasibility of that intervention.
  • 33:23So,
  • 33:24there has been, collaborative models
  • 33:26for severe mental illness and
  • 33:28LMICs. Like, Vikram Patel did
  • 33:30one with late, community health
  • 33:32providers, but not with, you
  • 33:34know, traditional healers and religious
  • 33:35leaders. We had graduated did
  • 33:36one in Nigeria, but it
  • 33:38was in the context of
  • 33:39prayer camps. So prayer camps
  • 33:40in West Africa are where
  • 33:42hundreds of people with severe
  • 33:43mental illness are all together,
  • 33:44and that's a model that's
  • 33:45pretty exclusive to West Africa
  • 33:47only. So this is this
  • 33:49this could be a template
  • 33:50in how we work with
  • 33:51with existing care systems
  • 33:53in delivering care to severe
  • 33:54mental illness, including in the
  • 33:56United States.
  • 33:58So
  • 33:59and another r thirty four,
  • 34:00that I have planned, I
  • 34:01submitted a pilot grant to,
  • 34:03Sierra,
  • 34:05regarding this,
  • 34:06is a client with care
  • 34:07models for for depression. So,
  • 34:09you know, group psychotherapy has
  • 34:11been shown to be very
  • 34:12effective in treating depression in
  • 34:13LMI C settings.
  • 34:15So, you know, why don't
  • 34:16we train people that people
  • 34:17already go for depression, like
  • 34:18religious leaders, you know, traditional
  • 34:20healers,
  • 34:21and better the effectiveness?
  • 34:23So those are, you know,
  • 34:23some of the other, research
  • 34:25aims too.
  • 34:26And some potential directions that
  • 34:28we haven't really, collected preliminary
  • 34:30data for, but we're planning
  • 34:31to this summer,
  • 34:33is, the overlap between education
  • 34:35and mental health.
  • 34:37So school discontinuation is, like,
  • 34:39a major issue,
  • 34:40you know,
  • 34:42in LMICs and in Uganda,
  • 34:44in America too. But, you
  • 34:45know,
  • 34:47if you go to the
  • 34:47school in Uganda,
  • 34:49in the area that we
  • 34:50work, so there's a lot
  • 34:51of regional disparities as well.
  • 34:53But, in first grade, there
  • 34:54might be two hundred people
  • 34:55enrolled. So there's, like, a
  • 34:56roster at the school showing
  • 34:57you how many people are
  • 34:58enrolled in in each grade.
  • 35:00So grade one, two hundred
  • 35:01people. By the time you
  • 35:02get to grade six, like,
  • 35:03sixth grade, there's ten people.
  • 35:05So school discontinuation is, like,
  • 35:07a major issue.
  • 35:09So and, you know, it's
  • 35:10also I don't associated, like,
  • 35:12as, like, a very traumatic
  • 35:13experience for a lot of
  • 35:14people,
  • 35:16not being able to afford
  • 35:17to continue going to school.
  • 35:19So, like, what if you
  • 35:20can combine a psychological and
  • 35:22an economic intervention,
  • 35:23creating a community mentorship system,
  • 35:25a vocational training system in
  • 35:27the community
  • 35:28that, that
  • 35:30that can, you know, empower
  • 35:32people at, like, a very
  • 35:33critical phase of their lives.
  • 35:35So we're collecting some preliminary
  • 35:37data for this this summer.
  • 35:38So hopefully, this this can
  • 35:39become another potential aim.
  • 35:42So this is just generally
  • 35:44my five year plan. For
  • 35:45the sake of simplicity, I
  • 35:46made a
  • 35:48for the sake of simplicity
  • 35:49simplicity, I made the assumption
  • 35:50that it'll take each grant
  • 35:51one resubmission to receive it.
  • 35:54So, you know, several paths
  • 35:55to, like, r ones and
  • 35:56becoming an independent researcher. I'm
  • 35:58also very interested in, taking
  • 35:59some of the lessons, centered
  • 36:01around community based interventions to
  • 36:03the United States.
  • 36:04For example, in in the
  • 36:05elderly, in the United States,
  • 36:07loneliness is a huge epidemic.
  • 36:09So is, like, elderly, you
  • 36:10know, a common mental illnesses
  • 36:12as well. So and and
  • 36:13treatment in America, I feel
  • 36:15like a lot of times
  • 36:16is very devoid of community
  • 36:17aspects. So what if we
  • 36:18can train activity managers at
  • 36:20nursing homes too in providing
  • 36:21group psychotherapy,
  • 36:23right, and measure outcomes that
  • 36:25way. So so some more
  • 36:26directions that I'm interested in
  • 36:28as well, domestically too.
  • 36:32So we're gonna actually save
  • 36:33questions until the end of
  • 36:35the end of,
  • 36:37our overall talk.
  • 36:38But, you know, it's a
  • 36:40pleasure to introduce,
  • 36:41another
  • 36:42one of my, colleagues, Marcus.
  • 36:45He's been a he he's
  • 36:46a chief resident of,
  • 36:49of the residency,
  • 36:50currently.
  • 36:51He's a member of the
  • 36:54Yaqui tribe in Arizona,
  • 36:56and he's a leader in
  • 36:57his community as well. And,
  • 36:59you know, I I had
  • 36:59the privilege of visiting him
  • 37:01in Tucson,
  • 37:02like, last month, and I
  • 37:04saw how much
  • 37:05how much he means and
  • 37:06how much it means that,
  • 37:07you know, he's achieved what
  • 37:08he has achieved to this
  • 37:09degree, to his community, to
  • 37:10thousands of people in this
  • 37:11community.
  • 37:13And I think it's like
  • 37:14and, you know, his plan
  • 37:15is to go back to
  • 37:15Arizona,
  • 37:16work with his community, and,
  • 37:18you know, empower his community,
  • 37:20and better better mental health
  • 37:21care. So,
  • 37:23so it's an honor to
  • 37:23be a co resident with
  • 37:25you. And,
  • 37:27yeah. And I'll Thanks for
  • 37:28that, Dave.
  • 37:33Well, good morning, everyone.
  • 37:36For
  • 37:37time purposes, I'll there will
  • 37:39be some slides
  • 37:40I skip and also because
  • 37:41I just realized I gave
  • 37:42Matt the wrong version,
  • 37:44but it's mostly there. So
  • 37:46we'll jump right into it.
  • 37:47It it's kinda fitting. I
  • 37:48I didn't I don't think
  • 37:49we planned this, but the
  • 37:50way we really started with,
  • 37:52you know, Matt's, like, systems
  • 37:53level
  • 37:54kind of view, Jay at
  • 37:56the country level, and then
  • 37:57going further and further down,
  • 37:58looking at the community level
  • 38:00and at a much smaller
  • 38:01scale of of what I've
  • 38:02been doing. So
  • 38:04I have been involved,
  • 38:05with
  • 38:07basically two projects longitudinally
  • 38:09since I've been in residency
  • 38:10related to, community health needs
  • 38:13assessments and stigma reduction. So
  • 38:15I'll be talking about two
  • 38:16projects mostly because they they
  • 38:18tie together.
  • 38:19So the first thing I
  • 38:20wanna jump in with, just
  • 38:21to give you guys a
  • 38:22backdrop of, like, who we're
  • 38:22talking about. So as Jay
  • 38:24mentioned,
  • 38:24this is the Pascua Yaqui
  • 38:26tribe. This is the tribe
  • 38:27that I'm from.
  • 38:28There is a unique setup
  • 38:30here where the tribe is
  • 38:31concentrated in the southwestern United
  • 38:33States, both in the US
  • 38:35and on the Mexican side
  • 38:36of the border. Roughly ten
  • 38:37thousand,
  • 38:39enrolled members in the United
  • 38:40States, another thirty thousand in
  • 38:41Mexico.
  • 38:42The largest clustering is our
  • 38:44reservation in Southern Arizona where
  • 38:46I'm from. It's just outside
  • 38:47of Tucson.
  • 38:48But we do have smaller
  • 38:49metro community areas in Tucson
  • 38:51and Phoenix,
  • 38:52Central Arizona. There's also a
  • 38:54small community in Texas and,
  • 38:56Southern California,
  • 38:58just to give you a
  • 38:58backdrop of who this is.
  • 39:01And the relevance. Relevance to
  • 39:02global health. Native Americans occupy
  • 39:04a really odd space in
  • 39:05America because, you know, they're
  • 39:07American citizens, but they often
  • 39:09live in communities that are
  • 39:10designated, you know, not entities
  • 39:12of the United States. And
  • 39:13because of that, there's a
  • 39:14lot of different ideas around
  • 39:15mental health, around, you know,
  • 39:17how treatment is received in
  • 39:18these communities.
  • 39:20The other just pure relevance
  • 39:21point from a psychiatric
  • 39:23standpoint is, you know, Native
  • 39:25Americans, if you look at
  • 39:25health disparities
  • 39:27for substance use,
  • 39:28for trauma disorders,
  • 39:29highest rate of any ethnic
  • 39:31group, and it's really not
  • 39:32close.
  • 39:33There's also a really,
  • 39:35you know,
  • 39:36lot of research out there
  • 39:37that talks about the completion
  • 39:39of suicide in these communities
  • 39:40being really just off the
  • 39:41charts. And despite these
  • 39:43depths of despair,
  • 39:44very often, you know, there's
  • 39:46not a lot of access
  • 39:47to behavioral health centers and
  • 39:48services, and really a lot
  • 39:50of resistance for native communities
  • 39:52to engage with Western medicine.
  • 39:54And we'll talk a little
  • 39:54bit about why.
  • 39:57Don't just take my word
  • 39:58for it. So this is
  • 39:59from the CDC.
  • 40:00This was released in twenty
  • 40:01twenty one. This trend goes
  • 40:03back much further than twenty
  • 40:05fifteen.
  • 40:06That top blue bar you
  • 40:07see there is the, suicide
  • 40:09completion rate by,
  • 40:11Native Americans. And then that
  • 40:13black bar there is the
  • 40:15white population in the US.
  • 40:16That dotted gray line is
  • 40:18the US average. And then
  • 40:19everyone else kinda clusters together.
  • 40:21As you can see, one
  • 40:22of the odd things, twenty
  • 40:23nineteen, I guess not odd,
  • 40:24not surprising. This disparity started
  • 40:26to worsen a little bit.
  • 40:27We think in response to
  • 40:29the COVID nineteen pandemic,
  • 40:31all minority populations saw a
  • 40:33little bit of an increase
  • 40:34around then.
  • 40:36I like to include this
  • 40:37just to give people a
  • 40:38backdrop of what we're dealing
  • 40:39with and also just show,
  • 40:40you know, the disparity is
  • 40:41pretty significant in these communities,
  • 40:43particularly
  • 40:44for native populations living in
  • 40:46reservation communities.
  • 40:49So what have we been
  • 40:50doing about it? So back,
  • 40:52in twenty twenty two, during
  • 40:54my PGY2 year,
  • 40:56I used my case rotation
  • 40:59here at Yale, the, clinical
  • 41:00and academic selective experience to
  • 41:03basically work with my tribal
  • 41:05health department
  • 41:06on
  • 41:07what was our first really
  • 41:09broad
  • 41:10community health needs assessments focused
  • 41:11on behavioral health. And to
  • 41:13do this with,
  • 41:15basically to do this with
  • 41:16validated scales and screening metrics,
  • 41:18because we didn't have a
  • 41:20lot of people utilizing behavioral
  • 41:21healthcare services, unfortunately.
  • 41:23Although we had a suspicion
  • 41:24based on national trends that
  • 41:25there should be a lot
  • 41:26of this in the community.
  • 41:28So we ended up getting
  • 41:29a pretty good sample size.
  • 41:30This was more than I'd
  • 41:31ever been surveyed for behavioral
  • 41:32health purposes in my community.
  • 41:34Keep in mind, like I
  • 41:35said, the reservation's roughly about
  • 41:36five thousand ish people,
  • 41:38but we were surveying people
  • 41:39also in the surrounding,
  • 41:41metro areas.
  • 41:42So we ended up,
  • 41:44having
  • 41:45PHQ score on there, a
  • 41:47PC five, an audit for
  • 41:48alcohol use disorder screening.
  • 41:50Not surprising.
  • 41:51Some of the results per
  • 41:53se as far as, like,
  • 41:53what we were expecting was
  • 41:54in line with you know,
  • 41:55we know there's a high
  • 41:56prevalence of trauma. We know
  • 41:57there's a high prevalence
  • 41:59of potentially PTSD,
  • 42:01anxiety,
  • 42:02substance use disorders.
  • 42:04The thing that we were
  • 42:05trying to kinda demonstrate was
  • 42:06even people who were screening
  • 42:07positive on these metrics were
  • 42:10not reaching out for health
  • 42:11care services, and even less
  • 42:12were being seen. So, really,
  • 42:14we're seeing almost nobody who's
  • 42:16screening positive.
  • 42:17And our question is why?
  • 42:19What's going on? Why is
  • 42:20nobody utilizing what's out there?
  • 42:22Because the tribe does have
  • 42:23a behavioral health department that
  • 42:25has really expanded and has
  • 42:26really, you know, tried to
  • 42:27to bring in people to
  • 42:29to receive treatment. But we
  • 42:30got a lot of responses
  • 42:31like this. So things talking
  • 42:33about stigma, talking about
  • 42:35concerns related to being judged.
  • 42:37And, I mean, the other
  • 42:38flavor we got from a
  • 42:39lot of people in some
  • 42:40of these qualitative feedbacks
  • 42:42were related to people saying
  • 42:43that's not a medical problem.
  • 42:44I wouldn't go to someone
  • 42:45for that. That's the family
  • 42:46problem. That's a unit problem.
  • 42:47That's a community problem. Why
  • 42:49would I talk to my
  • 42:50doctor about that?
  • 42:51The other piece of it
  • 42:52was there was, you know,
  • 42:54we gleaned a lot of
  • 42:56evidence
  • 42:56suggesting
  • 42:57there wasn't a lot of
  • 42:59health literacy related to behavioral
  • 43:01health and and frankly, just
  • 43:02a lot of internalized stigma
  • 43:03around it.
  • 43:04So
  • 43:05how I, you know, attempted
  • 43:07to continue this project and
  • 43:09continue,
  • 43:11you know, addressing some of
  • 43:12these disparities
  • 43:13was through,
  • 43:15I was fortunate to get
  • 43:16some funding through the APA
  • 43:18SAMHSA fellowship to,
  • 43:20pilot a project that I
  • 43:21call Project STAR, strengthening tribal
  • 43:23awareness and resilience.
  • 43:26Fun fact, for those of
  • 43:27you who are interested in,
  • 43:28like, Native American cosmology and
  • 43:31origin stories, for a lot
  • 43:32of Mesoamerican
  • 43:33tribes in particular, they will
  • 43:35refer to themselves as the
  • 43:36people of the stars. You
  • 43:37can look at it a
  • 43:38bunch of different ways, but
  • 43:39the cheeky name is kind
  • 43:40of a nod to to
  • 43:42that origin.
  • 43:44So what were our objectives?
  • 43:45What were we trying to
  • 43:46do here?
  • 43:47Number one, just community engagement.
  • 43:48So we really wanted to
  • 43:50bring the community in, educate
  • 43:52community members about
  • 43:53the
  • 43:55about
  • 43:56how, behavioral health is important
  • 43:58and also do it in
  • 43:59a culturally appropriate way. We
  • 44:01wanted to open the dialogue
  • 44:03and really just get community
  • 44:04members, you know, out in
  • 44:05the open talking about this
  • 44:06and bringing in people with
  • 44:08lived experience, which goes with
  • 44:10our collaborative partnership. So with
  • 44:11the grant, I was able
  • 44:12to bring in speakers who,
  • 44:14you know, we paid them
  • 44:15whether they were,
  • 44:17some were tribal members, some
  • 44:18were involved just with the
  • 44:20tribal health department and and
  • 44:22the behavioral health department and,
  • 44:23you know, doing work with
  • 44:24the MAT clinic that we
  • 44:25have there or, you know,
  • 44:27as counselors.
  • 44:28And
  • 44:29the other piece of it
  • 44:30was really compiling a list
  • 44:32of resources and, and just
  • 44:33kind of educating the masses,
  • 44:35like, these are the services
  • 44:36out there, this is something
  • 44:37that medicine can help with,
  • 44:38this is something that our
  • 44:39services can help with, we
  • 44:40need to start utilizing these
  • 44:41and, and also there's an
  • 44:43incorporation of alternative med practices
  • 44:45for the tribe too. So
  • 44:46we wanted to just let
  • 44:47people know that you don't
  • 44:48have to choose one or
  • 44:48the other, there is a
  • 44:49bridge that's available. And we're
  • 44:50trying to increase that.
  • 44:52So how we went about
  • 44:53it.
  • 44:55There is a community
  • 44:57attitudes of mental illness scale.
  • 44:59There's not a lot of
  • 45:01great scales out there for
  • 45:02assessing stigma. This one I've
  • 45:03seen replicated in a lot
  • 45:05of different languages and studies.
  • 45:07Essentially, a higher score on
  • 45:09that correlates with a more
  • 45:10positive attitude towards mental illness.
  • 45:12So we did this before,
  • 45:14the project started. We gathered
  • 45:15some demographic data. We ran
  • 45:17a whole awareness campaign that
  • 45:18went over the course
  • 45:20of, really, actively about six
  • 45:22months, but in terms of
  • 45:23the planning and everything else,
  • 45:24it's over the course of
  • 45:25a year. And then the
  • 45:26crux of our opening the
  • 45:28dialogue, opening the conversation to
  • 45:30the community were these town
  • 45:31hall style events where, you
  • 45:33know, I flew back periodically.
  • 45:34We would have these broadcast
  • 45:36on
  • 45:37the tribe social media pages.
  • 45:39They're still up on their
  • 45:40Facebook live pages, and they
  • 45:42save the videos and catalog
  • 45:43them there.
  • 45:44And we would have people
  • 45:45who were
  • 45:46experts in, you know, community
  • 45:48mental health, native health, native
  • 45:50well-being,
  • 45:51people who were doing work
  • 45:52in the community. They each
  • 45:53had, like, a different topic
  • 45:54and focus, which we'll we'll
  • 45:55talk about. And then at
  • 45:56the end of it all,
  • 45:57basically, we repeated the the
  • 45:59scale, and we were looking
  • 46:01at attendees versus non attendees
  • 46:03in person. A crude metric,
  • 46:04but really more so just
  • 46:05to kind of get people
  • 46:07involved in this and see
  • 46:08if this is something we
  • 46:09should sustainably do moving forward.
  • 46:12So I just wanna show
  • 46:13you guys, like, what the
  • 46:14scale is. It's a cool,
  • 46:15nifty little tool, basically, that,
  • 46:17you know, it scores it
  • 46:18on a Likert style scale.
  • 46:20And, the long form is
  • 46:22forty questions.
  • 46:24The short form, which has
  • 46:25been validated and replicated against
  • 46:27itself,
  • 46:28is only twenty questions. So
  • 46:29it's not really cumbersome from
  • 46:31a time standpoint. It's pretty,
  • 46:33oops, pretty easy to,
  • 46:35go about it in that
  • 46:36way.
  • 46:39Whoops, sorry.
  • 46:41Just to talk about like
  • 46:42our community messaging and our
  • 46:44meetings, what they look like.
  • 46:45So,
  • 46:46we have a
  • 46:48pretty nifty,
  • 46:51youth council who does a
  • 46:52lot of social media messaging.
  • 46:53And we really just ramped
  • 46:55that up during, you know,
  • 46:56the time of my project
  • 46:57to bring awareness to things
  • 46:59related to addiction, things related
  • 47:00to behavioral health services.
  • 47:03We also had a lot
  • 47:04of these signs posted out
  • 47:05in the community with tribal
  • 47:07symbols, tribal language, numbers to
  • 47:09crisis lines, numbers to alternative
  • 47:11medicine, to Centered Spirit, which
  • 47:12is the main behavioral health
  • 47:14center there.
  • 47:15Everybody I knew in the
  • 47:16community, I made sure to
  • 47:17give them multiple signs as
  • 47:18we're at every gate, every
  • 47:20door,
  • 47:21the community wellness center, all
  • 47:23over the place.
  • 47:25But the crux of it,
  • 47:26as I mentioned, were these
  • 47:27events. So these mind matters
  • 47:28town hall events, as I
  • 47:29mentioned, we we broadcast them
  • 47:31on Zoom. We had them
  • 47:32on Facebook Live. The tribal
  • 47:34media team was involved. And
  • 47:35all of these people were
  • 47:37either community members or people
  • 47:38directly involved with health care
  • 47:40for the tribe and, behavioral
  • 47:42health.
  • 47:43We had sessions focused on
  • 47:44addiction,
  • 47:45on youth resilience, on, trauma
  • 47:47and resilience healing, which ended
  • 47:49up being our most well
  • 47:51attended in person and also
  • 47:52just offline, like, by views
  • 47:54and videos shared, session.
  • 47:57The in person sessions, obviously,
  • 47:59you know, we had food.
  • 47:59We had, like, these speakers
  • 48:01come in. They were paid
  • 48:02for their time.
  • 48:04The lived experience side of
  • 48:05things, I can't underscore
  • 48:07just because
  • 48:08there was
  • 48:09this gentleman up here, you
  • 48:11know, talked about his journey.
  • 48:13Oops, sorry. Back.
  • 48:17Whites.
  • 48:18Whoops, sorry.
  • 48:21One of these gentlemen's here
  • 48:23was, part of the, the
  • 48:24tribal methadone program and talked
  • 48:25about, you know, his time
  • 48:27and, and how recovery does
  • 48:29happen. Really just giving people
  • 48:30voice and hope. And it's
  • 48:32something that means a lot
  • 48:33more when it's coming from
  • 48:34someone, you know, essentially.
  • 48:36Really well attended
  • 48:38our,
  • 48:39viewership
  • 48:40for
  • 48:41the most popular video we
  • 48:42had online was like fifteen
  • 48:44thousand or something. So we
  • 48:45had, I mean, we got
  • 48:46to a pretty big audience
  • 48:47considering this was shared beyond
  • 48:49just, you know, our tribal
  • 48:50community, but other tribal communities
  • 48:52in Arizona who are interested
  • 48:53in the model and interested
  • 48:54in kind of how to
  • 48:55get the word out about
  • 48:56these services.
  • 48:58I'll talk about outcomes. There's
  • 49:00some typos on this next
  • 49:02slide.
  • 49:03You know, effectively, what we
  • 49:04were able to show and
  • 49:05see was there is at
  • 49:07least in the short term,
  • 49:08some change related to attitudes,
  • 49:10stigmatizing attitudes towards mental illness.
  • 49:12So unsurprisingly,
  • 49:14people who,
  • 49:16showed up in person pre
  • 49:18any of this exposure, pre
  • 49:19any of the
  • 49:20teachings or psychoeducation, they already
  • 49:22had a higher score. They
  • 49:24were already less stigmatizing on
  • 49:25mental health, but that makes
  • 49:26sense because they're interested in
  • 49:27this. But But even for
  • 49:29that group, we were able
  • 49:30to see a mild increase.
  • 49:32The biggest increase we saw
  • 49:33was actually for people who
  • 49:34didn't attend anything in person.
  • 49:35So whether that was them
  • 49:37attending via just online, seeing
  • 49:39the messaging in the community.
  • 49:40We have a a nifty
  • 49:42little app called Nixle where
  • 49:43I can basically news blast
  • 49:45and give people announcements about
  • 49:46ongoings in the tribe at
  • 49:48any time. So it gives
  • 49:49me the ears of, like,
  • 49:49five thousand people.
  • 49:51Whether it's just that, whether
  • 49:53it was just hearing from
  • 49:54word-of-mouth,
  • 49:55there's some changes
  • 49:56effectively. We're trying to replicate
  • 49:58this and see kind of
  • 49:59similar to Jay's project if
  • 50:00there's longitudinal results at six
  • 50:02months at one year, which
  • 50:03will happen this year.
  • 50:05Qualitatively,
  • 50:07we did have quite a
  • 50:08bit
  • 50:09of resource guides that came
  • 50:11out of this. And just
  • 50:12also, we, you know, had
  • 50:13like QR codes and things
  • 50:15that are sent out to
  • 50:15people just as reminders. Like
  • 50:17this is where you find
  • 50:18all the services, even if
  • 50:19you're not going within the
  • 50:20tribe, but some people are
  • 50:21reluctant to because they don't
  • 50:22want to run into people
  • 50:23they know.
  • 50:24This is where you find
  • 50:25services in Tucson or, you
  • 50:27know, Southern Arizona type thing.
  • 50:29For scalability,
  • 50:31so I'm part of a
  • 50:33center through the University of
  • 50:34Arizona that recently formed focus
  • 50:36on native American health.
  • 50:38This center, right now has
  • 50:40partnerships with multiple tribes in
  • 50:42the Four Corners region, some
  • 50:43in the Midwest now.
  • 50:45They're interested in this project.
  • 50:46We're trying to figure out
  • 50:47a way to scale it
  • 50:48so that we can have
  • 50:49a similar model and a
  • 50:50curriculum built where tribes who
  • 50:52are kind of in the
  • 50:53process of developing their behavioral
  • 50:55health centers and really ramping
  • 50:56up services and connection can
  • 50:57start,
  • 50:59with something at least. Some
  • 51:00kind of way to to
  • 51:01know that we're we're addressing
  • 51:02stigma, we're addressing service underutilization.
  • 51:07Just to give some acknowledgements
  • 51:09to to these folks. So,
  • 51:11our medical director, doctor Renteria,
  • 51:13this dude,
  • 51:14been with the tribe for
  • 51:15a long time. He,
  • 51:17was my primary care doc
  • 51:19growing up.
  • 51:20He's been super involved with
  • 51:22a lot of efforts. He's
  • 51:23approaching retirement, which I worry
  • 51:25about.
  • 51:27Our tribal health department has
  • 51:28partnered with me for a
  • 51:29number of endeavors, and we
  • 51:30have a great working relationship
  • 51:32as well as with our
  • 51:33tribal council and obviously
  • 51:35APA SAMHSA for putting the
  • 51:36bill for this specifically.
  • 51:39And then one last shameless
  • 51:40plug. So upcoming next month,
  • 51:42the Global Health Group will
  • 51:44have one of our seminar
  • 51:45series speakers, Doctor. Maval, coming
  • 51:47in to talk about his
  • 51:48work in, building bridges across
  • 51:50the globe, developing joint collaboration,
  • 51:53and interprofessional
  • 51:54addiction education.
  • 51:58I know we're ahead of
  • 51:59time or maybe right on
  • 52:00time, but I didn't wanna
  • 52:01leave a chance for questions
  • 52:03for everyone because I know
  • 52:04we kind of deferred
  • 52:06till the end. So if
  • 52:07you guys wanna