Jonghun Kim
Associate Research Scientist in GeneticsAbout
Research
Publications
2026
Human amygdala-like telencephalic organoids model stress circuitry in assembloid systems
Yang W, Choe M, Lo C, Liu H, Cho Y, Kim J, Kiral F, Scandura M, Lu X, Kim K, Na K, Qiu C, Wu F, Dirks A, Mathew R, Cakir B, Cha H, Kim S, Cox A, Chung S, Jiang Y, Shin K, Lee S, Park I. Human amygdala-like telencephalic organoids model stress circuitry in assembloid systems. Cell Stem Cell 2026, 33: 1144-1160.e9. PMID: 42184826, PMCID: PMC13289835, DOI: 10.1016/j.stem.2026.04.021.Peer-Reviewed Original ResearchEstablishing Area-Specific Brain Organoids Through Transcription Factor-Mediated Patterning
Kim J, Jang Y, Lee M, Choi N, Jung Y, Lim J, Kwak T. Establishing Area-Specific Brain Organoids Through Transcription Factor-Mediated Patterning. Biology 2026, 15: 488. PMID: 41892247, PMCID: PMC13024533, DOI: 10.3390/biology15060488.Peer-Reviewed Original Research
2025
Generation of human pineal gland organoids with melatonin production for disease modeling
Kiral F, Yang W, Iyilikci O, Lu X, Kim J, Choe M, Lo C, Zhong M, Kim K, Jiang Y, Park I. Generation of human pineal gland organoids with melatonin production for disease modeling. Cell Stem Cell 2025, 33: 91-107.e9. PMID: 41475351, PMCID: PMC12925488, DOI: 10.1016/j.stem.2025.12.004.Peer-Reviewed Original ResearchKIAA0319 Plays a Critical Role in Cortical Neuronal Maturation and Synaptic Development Through a Dyslexia-Associated Gene Network
Scandura M, Choe M, Kiral F, Lo C, Kim J, Yang W, Qiu C, Ma Y, Gruen J, Park I. KIAA0319 Plays a Critical Role in Cortical Neuronal Maturation and Synaptic Development Through a Dyslexia-Associated Gene Network. Biological Psychiatry 2025, 100: 434-446. PMID: 41115623, DOI: 10.1016/j.biopsych.2025.10.014.Peer-Reviewed Original ResearchRadiofrequency regulates the BET-mediated pathways in radial glia differentiation in human cortical development
Cakir B, Tanaka Y, Choe M, Kiral F, Kim J, Micali N, Kang Y, Dharmadhikari B, Patterson B, Yang W, Cho Y, Xiang Y, Zhong M, Lee S, Patra P, Rakic P, Park I. Radiofrequency regulates the BET-mediated pathways in radial glia differentiation in human cortical development. Cell Reports 2025, 44: 116238. PMID: 40997800, PMCID: PMC12959456, DOI: 10.1016/j.celrep.2025.116238.Peer-Reviewed Original Research
2024
Identifying an Early Neuropathological Mechanism in Schizophrenia With Brain Organoids
Kim J, Park I. Identifying an Early Neuropathological Mechanism in Schizophrenia With Brain Organoids. Biological Psychiatry 2024, 95: 608-610. PMID: 38479977, DOI: 10.1016/j.biopsych.2024.01.015.Peer-Reviewed Original Research
2023
3D hepatic organoid production from human pluripotent stem cells
Jin Z, Xu K, Kim J, Guo H, Yao X, Xu Y, Li Y, Ryu D, Kim K, Hong K, Kim Y, Wang L, Cao Q, Kim K, Kim N, Han D. 3D hepatic organoid production from human pluripotent stem cells. Differentiation 2023, 135: 100742. PMID: 38104501, DOI: 10.1016/j.diff.2023.100742.Peer-Reviewed Original Research
2022
Non-coding de novo mutations in chromatin interactions are implicated in autism spectrum disorder
Kim I, Lee T, Lee J, Kim J, Lee S, Koh I, Kim J, An J, Lee H, Kim W, Ju Y, Cho Y, Yu S, Kim S, Oh M, Han D, Kim E, Choi J, Yoo H, Lee J. Non-coding de novo mutations in chromatin interactions are implicated in autism spectrum disorder. Molecular Psychiatry 2022, 27: 4680-4694. PMID: 35840799, DOI: 10.1038/s41380-022-01697-2.Peer-Reviewed Original Research
2021
Drug screening by uniform patient derived colorectal cancer hydro-organoids
Jung Y, Choi D, Park K, Lee S, Kim J, Kim H, Jeong H, Yang J, Kim J, Chung S, Min B. Drug screening by uniform patient derived colorectal cancer hydro-organoids. Biomaterials 2021, 276: 121004. PMID: 34273688, DOI: 10.1016/j.biomaterials.2021.121004.Peer-Reviewed Original Research
2020
Reprogramming progressive cells display low CAG promoter activity
Hu X, Wu Q, Zhang J, Kim J, Chen X, Hartman AA, Eastman AE, Park I, Guo S. Reprogramming progressive cells display low CAG promoter activity. Stem Cells 2020, 39: 43-54. PMID: 33075202, PMCID: PMC7821215, DOI: 10.1002/stem.3295.Peer-Reviewed Original Research
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Feb 202715Monday
Yale Only Annabel Devault - Jonghun Kim