Ferdi Kiral
Associate Research Scientist in GeneticsAbout
Research
Publications
2026
Human amygdala-like telencephalic organoids model stress circuitry in assembloid systems
Yang W, Choe M, Lo C, Liu H, Cho Y, Kim J, Kiral F, Scandura M, Lu X, Kim K, Na K, Qiu C, Wu F, Dirks A, Mathew R, Cakir B, Cha H, Kim S, Cox A, Chung S, Jiang Y, Shin K, Lee S, Park I. Human amygdala-like telencephalic organoids model stress circuitry in assembloid systems. Cell Stem Cell 2026, 33: 1144-1160.e9. PMID: 42184826, PMCID: PMC13289835, DOI: 10.1016/j.stem.2026.04.021.Peer-Reviewed Original Research
2025
Generation of human pineal gland organoids with melatonin production for disease modeling
Kiral F, Yang W, Iyilikci O, Lu X, Kim J, Choe M, Lo C, Zhong M, Kim K, Jiang Y, Park I. Generation of human pineal gland organoids with melatonin production for disease modeling. Cell Stem Cell 2025, 33: 91-107.e9. PMID: 41475351, PMCID: PMC12925488, DOI: 10.1016/j.stem.2025.12.004.Peer-Reviewed Original ResearchKIAA0319 Plays a Critical Role in Cortical Neuronal Maturation and Synaptic Development Through a Dyslexia-Associated Gene Network
Scandura M, Choe M, Kiral F, Lo C, Kim J, Yang W, Qiu C, Ma Y, Gruen J, Park I. KIAA0319 Plays a Critical Role in Cortical Neuronal Maturation and Synaptic Development Through a Dyslexia-Associated Gene Network. Biological Psychiatry 2025, 100: 434-446. PMID: 41115623, DOI: 10.1016/j.biopsych.2025.10.014.Peer-Reviewed Original ResearchRadiofrequency regulates the BET-mediated pathways in radial glia differentiation in human cortical development
Cakir B, Tanaka Y, Choe M, Kiral F, Kim J, Micali N, Kang Y, Dharmadhikari B, Patterson B, Yang W, Cho Y, Xiang Y, Zhong M, Lee S, Patra P, Rakic P, Park I. Radiofrequency regulates the BET-mediated pathways in radial glia differentiation in human cortical development. Cell Reports 2025, 44: 116238. PMID: 40997800, PMCID: PMC12959456, DOI: 10.1016/j.celrep.2025.116238.Peer-Reviewed Original Research
2024
Telencephalic organoids as model systems to study cortical development and diseases
Yang W, Kiral F, Park I. Telencephalic organoids as model systems to study cortical development and diseases. Organoid 2024, 4: e1. DOI: 10.51335/organoid.2024.4.e1.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2023
Diencephalic organoids – A key to unraveling development, connectivity, and pathology of the human diencephalon
Kiral F, Choe M, Park I. Diencephalic organoids – A key to unraveling development, connectivity, and pathology of the human diencephalon. Frontiers In Cellular Neuroscience 2023, 17: 1308479. PMID: 38130869, PMCID: PMC10733522, DOI: 10.3389/fncel.2023.1308479.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsGeneration of ventralized human thalamic organoids with thalamic reticular nucleus
Kiral F, Cakir B, Tanaka Y, Kim J, Yang W, Wehbe F, Kang Y, Zhong M, Sancer G, Lee S, Xiang Y, Park I. Generation of ventralized human thalamic organoids with thalamic reticular nucleus. Cell Stem Cell 2023, 30: 677-688.e5. PMID: 37019105, PMCID: PMC10329908, DOI: 10.1016/j.stem.2023.03.007.Peer-Reviewed Original Research
2022
Advanced in vitro models: Microglia in action
Cakir B, Kiral F, Park I. Advanced in vitro models: Microglia in action. Neuron 2022, 110: 3444-3457. PMID: 36327894, DOI: 10.1016/j.neuron.2022.10.004.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2021
Brain connectivity inversely scales with developmental temperature in Drosophila
Kiral F, Dutta S, Linneweber G, Hilgert S, Poppa C, Duch C, von Kleist M, Hassan B, Hiesinger P. Brain connectivity inversely scales with developmental temperature in Drosophila. Cell Reports 2021, 37: 110145. PMID: 34936868, DOI: 10.1016/j.celrep.2021.110145.Peer-Reviewed Original ResearchSystematic functional analysis of Rab GTPases reveals limits of neuronal robustness to environmental challenges in flies
Kohrs F, Daumann I, Pavlovic B, Jin E, Kiral F, Lin S, Port F, Wolfenberg H, Mathejczyk T, Linneweber G, Chan C, Boutros M, Hiesinger P. Systematic functional analysis of Rab GTPases reveals limits of neuronal robustness to environmental challenges in flies. ELife 2021, 10: e59594. PMID: 33666175, PMCID: PMC8016483, DOI: 10.7554/elife.59594.Peer-Reviewed Original Research
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