Luoyi Li
About
Research
Publications
2025
Sugar coats shield immunogenic RNA modification:A new function for RNA glycosylation
Li L, Lu J. Sugar coats shield immunogenic RNA modification:A new function for RNA glycosylation. Molecular Cell 2025, 85: 3737-3739. PMID: 41106364, DOI: 10.1016/j.molcel.2025.09.027.Peer-Reviewed Original Research
2024
Protocol for detecting glycoRNAs using metabolic labeling and northwestern blot
Li L, Zhang N, Pantoja C, Wang Y, Lu J. Protocol for detecting glycoRNAs using metabolic labeling and northwestern blot. STAR Protocols 2024, 5: 103321. PMID: 39298321, PMCID: PMC11426122, DOI: 10.1016/j.xpro.2024.103321.Peer-Reviewed Original Research
2022
Endothelial PERK-ATF4-JAG1 axis activated by T-ALL remodels bone marrow vascular niche
Liu C, Chen Q, Shang Y, Chen L, Myers J, Awadallah A, Sun J, Yu S, Umphred-Wilson K, Che D, Dou Y, Li L, Wearsch P, Ramírez-Bergeron D, Beck R, Xin W, Jin G, Adoro S, Zhou L. Endothelial PERK-ATF4-JAG1 axis activated by T-ALL remodels bone marrow vascular niche. Theranostics 2022, 12: 2894-2907. PMID: 35401837, PMCID: PMC8965499, DOI: 10.7150/thno.67710.Peer-Reviewed Original ResearchConceptsT-ALLbone marrow vascular nicheunfolded protein responsevascular nicheHSC maintenancesmall extracellular vesiclesMethods:</b>acute T-cell lymphoblastic leukemiaconclusion:</b>T-cell lymphoblastic leukemiabone marrow endothelial cellsResults:</b>T-ALL xenograftsendothelial cellsbone marrow specimensmarrow endothelial cellsexpression of SCFup-regulatedpotential therapeutic opportunitiesanimal model studiesEC-specific deletionrobust activation
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Sep 202614Monday
Yale Only Tova Finkelstein - Luoyi Li