Taylor J. Keding, PhD
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Associate Research Scientist
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Taylor is an associate research scientist with Yale's Department of Psychology, working with Dr. Dylan Gee and the Clinical Affective Neuroscience & Development Lab. He has a joint appointment with the University of Wisconsin-Madison Department of Psychiatry, working with Dr. Ryan Herringa and the BRAVE Research Center. He received his Ph.D. in Neuroscience from the University of Wisconsin-Madison . His research broadly focuses on the development of emotion-related brain circuitry during childhood and adolescence, how circuit maturation is altered by early-life adversity, and how these alterations influence risk for pediatric psychopathology. His work utilizes neuroimaging (sMRI, fMRI, DTI), in combination with computational and predictive modeling approaches. In recognition of his work, Taylor has received numerous awards and honors from organizations such as the National Institutes of Mental Health, the National Science Foundation, the Brain and Behavior Research Foundation, the International Society for Traumatic Stress Studies, the Society for Biological Psychiatry, and the American College of Neuropsychopharmacology.
Appointments
Department of Psychology
Associate Research ScientistPrimary
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Education & Training
- PhD
- University of Wisconsin-Madison, Neuroscience (2021)
- BSc
- University of Wisconsin-Madison, Neurobiology (2014)
- BSc
- University of Wisconsin-Madison, Psychology (2014)
Research
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Medical Research Interests
ORCID
0000-0002-0507-6712- View Lab Website
Clinical Affective Neuroscience & Development Lab
Research at a Glance
Yale Co-Authors
Publications Timeline
Research Interests
Dylan Gee, PhD
Jutta Joormann
Bailey Holt-Gosselin
Sahana Kribakaran
Carla E Marin, PhD
Eli Lebowitz, PhD
Brain
Child Development
Machine Learning
Publications
Featured Publications
Neural Circuit Markers of Familial Risk for Depression Among Healthy Youths in the Adolescent Brain Cognitive Development Study
Holt-Gosselin B, Keding T, Poulin R, Brieant A, Rueter A, Hendrickson T, Perrone A, Byington N, Houghton A, Miranda-Dominguez O, Feczko E, Fair D, Joormann J, Gee D. Neural Circuit Markers of Familial Risk for Depression Among Healthy Youths in the Adolescent Brain Cognitive Development Study. Biological Psychiatry Cognitive Neuroscience And Neuroimaging 2023, 9: 185-195. PMID: 37182734, PMCID: PMC10640659, DOI: 10.1016/j.bpsc.2023.05.001.Peer-Reviewed Original ResearchCitationsAltmetricConceptsFamilial riskHR youthLR youthHealthy youthWhole-brain seedEarly-onset depressionResting-state FCYears of ageBrain-based markersFunctional connectivity patternsHigh familial riskCognitive Development StudyAdolescent Brain Cognitive Development (ABCD) studyMaternal riskLow familial riskMaternal historyFamily historyStriatal connectivityMaternal depressionDepression riskNucleus accumbensPsychiatric problemsNeural circuitsEarly detectionSmall sample sizeViolence Exposure and Amygdala-Prefrontal Circuit Maturation: Developmental Markers of Psychiatric Risk in Youth
Keding T, Herringa R. Violence Exposure and Amygdala-Prefrontal Circuit Maturation: Developmental Markers of Psychiatric Risk in Youth. Biological Psychiatry 2022, 91: s47-s48. DOI: 10.1016/j.biopsych.2022.02.140.Peer-Reviewed Original ResearchCitationsAltmetricDifferential Patterns of Delayed Emotion Circuit Maturation in Abused Girls With and Without Internalizing Psychopathology
Keding T, Heyn S, Russell J, Zhu X, Cisler J, McLaughlin K, Herringa R. Differential Patterns of Delayed Emotion Circuit Maturation in Abused Girls With and Without Internalizing Psychopathology. American Journal Of Psychiatry 2021, 178: 1026-1036. PMID: 34407623, PMCID: PMC8570983, DOI: 10.1176/appi.ajp.2021.20081192.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsChildhood abusePhysical neglectBrain Age Gap EstimationNormative brain developmentCircuit maturationBrain-wide patternsChildhood physical neglectEarly life adversityFronto-parietal cortexEmotion circuitsThreat generalizationGray matter volumePresence of psychopathologyResilient girlsLateral prefrontalHyperarousal symptomsInternalizing psychopathologyNeural contributorsAbused girlsInternalizing disorder diagnosesInternalizing diagnosesMaltreatment historyAbuse exposureAbuse historyNeurodevelopmental markersChildhood exposure to interpersonal violence is associated with greater transdiagnostic integration of psychiatric symptoms
Russell JD, Keding TJ, He Q, Li JJ, Herringa RJ. Childhood exposure to interpersonal violence is associated with greater transdiagnostic integration of psychiatric symptoms. Psychological Medicine 2020, 52: 1883-1891. PMID: 33161911, PMCID: PMC8106688, DOI: 10.1017/s0033291720003712.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsChildhood exposureIPV exposureTreatment-resistant populationStructured Clinical InterviewGreater psychiatric comorbidityMental health symptomsPotential clinical implicationsInterpersonal violencePopulation-representative sampleBridge symptomsPsychiatric comorbidityViolence-exposed youthPsychiatric symptomsTreatment resistanceSymptom communitiesClinical InterviewHealth symptomsMental illnessClinical implicationsSymptomsSymptom associationMultiple disordersViolence exposureDiagnostic statusPatterns of association
2025
Preadolescent Family Conflict, Parental Depression, and Neural Circuitry Interact to Predict Adolescent Symptoms
Holt-Gosselin B, Basol E, Keding T, Rodrigues K, Joormann J, Gee D. Preadolescent Family Conflict, Parental Depression, and Neural Circuitry Interact to Predict Adolescent Symptoms. Journal Of The American Academy Of Child & Adolescent Psychiatry 2025 PMID: 40882867, DOI: 10.1016/j.jaac.2025.08.014.Peer-Reviewed Original ResearchConceptsAdolescent Brain Cognitive DevelopmentFunctional connectivityFamily conflictFamilial riskParental depressionPsychiatric symptomsNeural circuitryAged 9Patterns of neurodevelopmentResting-state networksAdolescent psychopathologyLR youthHR youthInternalizing symptomsAdolescent symptomsDepression historyRisk statusTotal problemsEnvironmental adversityPsychopathologyCognitive developmentCross-sectional designDepressionEffect sizePrognostic risk markersExposure to unpredictable childhood environments is associated with amygdala activation during early extinction in adulthood
Duda J, Keding T, Kribakaran S, Odriozola P, Kitt E, Cohodes E, Zacharek S, McCauley S, Haberman J, Joormann J, Gee D. Exposure to unpredictable childhood environments is associated with amygdala activation during early extinction in adulthood. Developmental Cognitive Neuroscience 2025, 74: 101578. PMID: 40493990, PMCID: PMC12179744, DOI: 10.1016/j.dcn.2025.101578.Peer-Reviewed Original ResearchAltmetricConceptsUnpredictable childhood environmentsChildhood unpredictabilityExtinction learningAmygdala activationChildhood environmentAssociated with amygdala activationBasolateral amygdala activityChildhood trauma exposureSkin conductance responsesCross-species researchThreat cuesTrauma exposureNeural regionsSafety learningEarly adversityHealthy young adultsCurrent anxietyAssociated with activationConductance responsesCaregiving environmentAffective functioningHealthy neurodevelopmentNeural activityTargeted clinical interventionsIn adulthood11. Reduced Centromedial Amygdala Recruitment in Youth Independently Regulating Fear During a Parent-Focused Treatment for Pediatric Anxiety
Keding T, Kitt E, Broussard A, Ho G, Weeks G, Zacharek S, Nardini C, Hommel G, Marin C, Silverman W, Lebowitz E, Gee D. 11. Reduced Centromedial Amygdala Recruitment in Youth Independently Regulating Fear During a Parent-Focused Treatment for Pediatric Anxiety. Biological Psychiatry 2025, 97: s78. DOI: 10.1016/j.biopsych.2025.02.201.Peer-Reviewed Original Research144. Negative Life Events, Neural Circuitry, and Familial Risk for Depression Among Healthy Adolescents Interact to Predict the Onset of Psychopathology One Year Later
Holt-Gosselin B, Vives G, Keding T, Castrillon M, Joormann J, Gee D. 144. Negative Life Events, Neural Circuitry, and Familial Risk for Depression Among Healthy Adolescents Interact to Predict the Onset of Psychopathology One Year Later. Biological Psychiatry 2025, 97: s154. DOI: 10.1016/j.biopsych.2025.02.381.Peer-Reviewed Original ResearchPerson-centered analyses reveal that developmental adversity at moderate levels and neural threat/safety discrimination are associated with lower anxiety in early adulthood
Sisk L, Keding T, Ruiz S, Odriozola P, Kribakaran S, Cohodes E, McCauley S, Zacharek S, Hodges H, Haberman J, Pierre J, Caballero C, Baskin-Sommers A, Gee D. Person-centered analyses reveal that developmental adversity at moderate levels and neural threat/safety discrimination are associated with lower anxiety in early adulthood. Communications Psychology 2025, 3: 31. PMID: 40044923, PMCID: PMC11882445, DOI: 10.1038/s44271-025-00193-x.Peer-Reviewed Original ResearchCitationsAltmetricConceptsNeural activityAdverse exposuresMiddle childhoodLower anxietyAssociated with lower anxietyWithin-person combinationsPerson-centered analysesPerson-centered approachHigher neural activityPatterns of adversity exposureCorticolimbic circuitryModerate adversityParsing heterogeneityAnxiety symptomsSafety learningDevelopmental adversityLatent profilesLifetime adversityNeurobiological functionsFuture anxietyAnxietyEarly adulthoodAssociated with processesAdversityYoung adultsMultivariate Links Between the Developmental Timing of Adversity Exposure and White Matter Tract Connectivity in Adulthood
Sisk L, Keding T, Cohodes E, McCauley S, Pierre J, Odriozola P, Kribakaran S, Haberman J, Zacharek S, Hodges H, Caballero C, Gold G, Huang A, Talton A, Gee D. Multivariate Links Between the Developmental Timing of Adversity Exposure and White Matter Tract Connectivity in Adulthood. Biological Psychiatry Cognitive Neuroscience And Neuroimaging 2025, 10: 964-977. PMID: 39978462, PMCID: PMC12353986, DOI: 10.1016/j.bpsc.2025.02.003.Peer-Reviewed Original ResearchCitationsConceptsWhite matter tractsAdverse exposuresPreschool-ageMiddle childhoodMental health in adulthoodDevelopment of white matter tractsEarly-life adversitySymptoms in adulthoodChildhood adversity exposureDevelopmental timing of exposureMental health problemsTiming of adversity exposureMental health burdenCortico-cortical communicationIncreased mental health burdenTract connectivityNeurobiological changesHealth in adulthoodModes of covariationSensorimotor functionMultivariate linksMental healthAdversityAdulthoodHealth burden
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