Najla Arshad, PhD
Associate Research Scientist-Immunobiolgy
Research & Publications
Biography
News
Coauthors
Selected Publications
- SARS-CoV-2 accessory proteins ORF7a and ORF3a use distinct mechanisms to down-regulate MHC-I surface expressionArshad N, Laurent-Rolle M, Ahmed W, Hsu J, Mitchell S, Pawlak J, Sengupta D, Biswas K, Cresswell P. SARS-CoV-2 accessory proteins ORF7a and ORF3a use distinct mechanisms to down-regulate MHC-I surface expression. Proceedings Of The National Academy Of Sciences Of The United States Of America 2022, 120: e2208525120. PMID: 36574644, PMCID: PMC9910621, DOI: 10.1073/pnas.2208525120.
- Impact of Calreticulin and Its Mutants on Endoplasmic Reticulum Function in Health and DiseaseArshad N, Cresswell P. Impact of Calreticulin and Its Mutants on Endoplasmic Reticulum Function in Health and Disease. 2021, 59: 163-180. PMID: 34050866, DOI: 10.1007/978-3-030-67696-4_8.
- Platelet P-selectin initiates cross-presentation and dendritic cell differentiation in blood monocytesHan P, Hanlon D, Arshad N, Lee JS, Tatsuno K, Yurter A, Robinson E, Filler R, Sobolev O, Cote C, Rivera-Molina F, Toomre D, Fahmy T, Edelson R. Platelet P-selectin initiates cross-presentation and dendritic cell differentiation in blood monocytes. Science Advances 2020, 6: eaaz1580. PMID: 32195350, PMCID: PMC7065880, DOI: 10.1126/sciadv.aaz1580.
- Extracorporeal photochemotherapy induces bona fide immunogenic cell deathTatsuno K, Yamazaki T, Hanlon D, Han P, Robinson E, Sobolev O, Yurter A, Rivera-Molina F, Arshad N, Edelson RL, Galluzzi L. Extracorporeal photochemotherapy induces bona fide immunogenic cell death. Cell Death & Disease 2019, 10: 578. PMID: 31371700, PMCID: PMC6675789, DOI: 10.1038/s41419-019-1819-3.
- Tumor-associated calreticulin variants functionally compromise the peptide loading complex and impair its recruitment of MHC-IArshad N, Cresswell P. Tumor-associated calreticulin variants functionally compromise the peptide loading complex and impair its recruitment of MHC-I. Journal Of Biological Chemistry 2018, 293: 9555-9569. PMID: 29769311, PMCID: PMC6016473, DOI: 10.1074/jbc.ra118.002836.
- Cyclic nucleotide signaling in intestinal epithelia: getting to the gut of the matterArshad N, Visweswariah SS. Cyclic nucleotide signaling in intestinal epithelia: getting to the gut of the matter. WIREs Mechanisms Of Disease 2013, 5: 409-424. PMID: 23610087, DOI: 10.1002/wsbm.1223.
- Site-specific N-Linked Glycosylation of Receptor Guanylyl Cyclase C Regulates Ligand Binding, Ligand-mediated Activation and Interaction with Vesicular Integral Membrane Protein 36, VIP36*Arshad N, Ballal S, Visweswariah SS. Site-specific N-Linked Glycosylation of Receptor Guanylyl Cyclase C Regulates Ligand Binding, Ligand-mediated Activation and Interaction with Vesicular Integral Membrane Protein 36, VIP36*. Journal Of Biological Chemistry 2012, 288: 3907-3917. PMID: 23269669, PMCID: PMC3567644, DOI: 10.1074/jbc.m112.413906.
- The multiple and enigmatic roles of guanylyl cyclase C in intestinal homeostasisArshad N, Visweswariah SS. The multiple and enigmatic roles of guanylyl cyclase C in intestinal homeostasis. FEBS Letters 2012, 586: 2835-2840. PMID: 22819815, DOI: 10.1016/j.febslet.2012.07.028.
- Familial Diarrhea Syndrome Caused by an Activating GUCY2C MutationFiskerstrand T, Arshad N, Haukanes BI, Tronstad RR, Pham KD, Johansson S, Håvik B, Tønder SL, Levy SE, Brackman D, Boman H, Biswas KH, Apold J, Hovdenak N, Visweswariah SS, Knappskog PM. Familial Diarrhea Syndrome Caused by an Activating GUCY2C Mutation. New England Journal Of Medicine 2012, 366: 1586-1595. PMID: 22436048, DOI: 10.1056/nejmoa1110132.
- Guanylyl Cyclase ReceptorsVisweswariah S, Arshad N. Guanylyl Cyclase Receptors. 2012, 843-847. DOI: 10.1007/978-1-4419-0461-4_434.
- Receptor guanylyl cyclase C (GC-C): regulation and signal transductionBasu N, Arshad N, Visweswariah SS. Receptor guanylyl cyclase C (GC-C): regulation and signal transduction. Molecular And Cellular Biochemistry 2009, 334: 67-80. PMID: 19960363, DOI: 10.1007/s11010-009-0324-x.