W Dean Rupp, PhD
Professor Emeritus of Therapeutic RadiologyDownloadHi-Res Photo
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Therapeutic Radiology
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Professor Emeritus of Therapeutic Radiology
Appointments
Therapeutic Radiology
EmeritusPrimary
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Education & Training
- PhD
- Yale University, Pharmacology (1965)
- AB
- Oberlin College, Chemistry (1960)
Research
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Research at a Glance
Publications Timeline
A big-picture view of W Dean Rupp's research output by year.
73Publications
6,343Citations
Publications
2019
Replisome structure suggests mechanism for continuous fork progression and post-replication repair
Yang W, Seidman M, Rupp W, Gao Y. Replisome structure suggests mechanism for continuous fork progression and post-replication repair. DNA Repair 2019, 81: 102658. PMID: 31303546, PMCID: PMC7467748, DOI: 10.1016/j.dnarep.2019.102658.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsCitationsAltmetric
2015
Legacy Biological Materials
Klein R, Fontes B, Rupp W. Legacy Biological Materials. Applied Biosafety 2015, 20: 99-103. DOI: 10.1177/153567601502000205.Peer-Reviewed Original Research
2013
Early days of DNA repair: discovery of nucleotide excision repair and homology-dependent recombinational repair.
Rupp WD. Early days of DNA repair: discovery of nucleotide excision repair and homology-dependent recombinational repair. The Yale Journal Of Biology And Medicine 2013, 86: 499-505. PMID: 24348214, PMCID: PMC3848104.Peer-Reviewed Original ResearchCitationsAltmetric
2005
Discontinuities in the DNA synthesized in an excision-defective strain of Escherichia coli following ultraviolet irradiation. 1968.
Rupp WD, Howard-Flanders P. Discontinuities in the DNA synthesized in an excision-defective strain of Escherichia coli following ultraviolet irradiation. 1968. DNA Repair 2005, 4: 620-33. PMID: 15889457.Peer-Reviewed Original ResearchCitations
1998
A specific 3′ exonuclease activity of UvrABC
Gordienko I, Rupp W. A specific 3′ exonuclease activity of UvrABC. The EMBO Journal 1998, 17: 626-633. PMID: 9430653, PMCID: PMC1170412, DOI: 10.1093/emboj/17.2.626.Peer-Reviewed Original ResearchCitationsAltmetric
1997
UvrAB activity at a damaged DNA site: is unpaired DNA present?
Gordienko I, Rupp W. UvrAB activity at a damaged DNA site: is unpaired DNA present? The EMBO Journal 1997, 16: 880-888. PMID: 9049316, PMCID: PMC1169688, DOI: 10.1093/emboj/16.4.880.Peer-Reviewed Original ResearchCitationsMeSH Keywords2-AcetylaminofluoreneAdenosine TriphosphatasesBacterial ProteinsDNA AdductsDNA DamageDNA HelicasesDNA RepairDNA-Binding ProteinsDNA, Single-StrandedEndodeoxyribonucleasesEscherichia coliEscherichia coli ProteinsModels, GeneticMutationNucleic Acid ConformationNucleic Acid DenaturationOligodeoxyribonucleotidesThe limited strand‐separating activity of the UvrAB protein complex and its role in the recognition of DNA damage
Gordienko I, Rupp W. The limited strand‐separating activity of the UvrAB protein complex and its role in the recognition of DNA damage. The EMBO Journal 1997, 16: 889-895. PMID: 9049317, PMCID: PMC1169689, DOI: 10.1093/emboj/16.4.889.Peer-Reviewed Original ResearchCitationsAltmetricSabia Virus Incident at Yale University
Gandsman EJ, Aaslestad HG, Ouimeta T, Rupp W. Sabia Virus Incident at Yale University. AIHA Journal 1997, 58: 51-53. PMID: 9018837, DOI: 10.1080/15428119791013080.Peer-Reviewed Original ResearchCitationsAltmetric
1994
UvrABC Cutting at 3′ Recessed Termini of Undamaged DNA May Be a Model for 5′ Incision at Damaged Sitesa
RUPP W, GORDIENKO I. UvrABC Cutting at 3′ Recessed Termini of Undamaged DNA May Be a Model for 5′ Incision at Damaged Sitesa. Annals Of The New York Academy Of Sciences 1994, 726: 321-323. PMID: 8092693, DOI: 10.1111/j.1749-6632.1994.tb52839.x.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsCitations
1991
Requirement for the replication protein SSB in human DMA excision repair
Coverley D, Kenny M, Munn M, Rupp W, Lane D, Wood R. Requirement for the replication protein SSB in human DMA excision repair. Nature 1991, 349: 538-541. PMID: 1992355, DOI: 10.1038/349538a0.Commentaries, Editorials and LettersCitations
Academic Achievements & Community Involvement
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Honors
honor The 1986 Weiss Medal
06/12/1986International AwardAssociation for Radiation Research, UKDetailsUnited Kingdomhonor The 1976 Radiation Research Award (later renamed The Michael Fry Award)
05/07/1976International AwardRadiation Research Society, USADetailsUnited States
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Therapeutic Radiology
PO Box 208040
New Haven, CT 06520-8040
United States