Rui Wang
Postdoctoral FellowAbout
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Featured Publications
Gut Microbiota-Derived Butyrate Induces Epigenetic and Metabolic Reprogramming in Myeloid-Derived Suppressor Cells to Alleviate Primary Biliary Cholangitis
. Gut Microbiota-Derived Butyrate Induces Epigenetic and Metabolic Reprogramming in Myeloid-Derived Suppressor Cells to Alleviate Primary Biliary Cholangitis. Gastroenterology 2024, 167: 733-749.e3. PMID: 38810839, DOI: 10.1053/j.gastro.2024.05.014.Peer-Reviewed Original ResearchImmunosuppression induces regression of fibrosis in primary biliary cholangitis with moderate-to-severe interface hepatitis
Wang R, Lin Q, Lu Z, Wen H, Hu F, You J, He Y, Fang Y, Bian Z, Hou Q, Ju Z, Wang Y, Lian M, Xiao X, Sheng L, Guo C, Hua J, Tang R, You Z, Chen X, Gershwin M, Huang Z, Wang Q, Miao Q, Ma X. Immunosuppression induces regression of fibrosis in primary biliary cholangitis with moderate-to-severe interface hepatitis. Journal Of Autoimmunity 2024, 143: 103163. PMID: 38301505, DOI: 10.1016/j.jaut.2023.103163.Peer-Reviewed Original Research
2026
Phage therapy targeting DNA-encapsulated membrane vesicle-producing intestinal symbiotic Klebsiella pneumoniae ameliorates autoimmune disease
Pu B, Wang R, Wang J, Li L, Li J, Cai M, Zhong Y, Yan B, Lv L, Zhang Y, Dong K, Luo J, Li H, Chen X, Zhou Q, Liu C, Tang R, Ma X, Guo X, Zhao W, Qin J. Phage therapy targeting DNA-encapsulated membrane vesicle-producing intestinal symbiotic Klebsiella pneumoniae ameliorates autoimmune disease. Npj Biofilms And Microbiomes 2026, 12: 110. PMID: 41951679, PMCID: PMC13237050, DOI: 10.1038/s41522-026-00981-1.Peer-Reviewed Original ResearchGlycoursodeoxycholic acid regulates peritoneal monocytic myeloid-derived suppressor cells to alleviate systemic inflammation in decompensated cirrhosis
Wang R, Wang B, Li B, Zhang J, Li Y, Jiang C, Ji P, Tang R, You Z, Xiao X, Guo C, Miao Q, Hua J, Li H, Timilsina S, Gershwin M, Wang Q, Ma X, Lian M. Glycoursodeoxycholic acid regulates peritoneal monocytic myeloid-derived suppressor cells to alleviate systemic inflammation in decompensated cirrhosis. Journal Of Autoimmunity 2026, 160: 103554. PMID: 41955910, DOI: 10.1016/j.jaut.2026.103554.Peer-Reviewed Original Research
2025
Tryptophan catabolites from microbiota ameliorate immune-mediated hepatitis through activating aryl hydrocarbon receptor of T cells
Li B, Liang X, Li Y, Wang R, Wei Y, Liu Q, Zhang J, Wang Q, Miao Q, Xiao X, Lian M, Wang Z, Zhou Y, Gershwin M, You Z, Tang R, Ma X. Tryptophan catabolites from microbiota ameliorate immune-mediated hepatitis through activating aryl hydrocarbon receptor of T cells. Gut Microbes 2025, 17: 2557979. PMID: 40995824, PMCID: PMC12477874, DOI: 10.1080/19490976.2025.2557979.Peer-Reviewed Original ResearchOptimizing the tapering scheme of corticosteroid treatment for acute onset of autoimmune hepatitis
. Optimizing the tapering scheme of corticosteroid treatment for acute onset of autoimmune hepatitis. Journal Of Autoimmunity 2025, 152: 103387. PMID: 40015068, DOI: 10.1016/j.jaut.2025.103387.Peer-Reviewed Original Research
2024
Gut microbiome pattern impacts treatment response in primary biliary cholangitis
. Gut microbiome pattern impacts treatment response in primary biliary cholangitis. Med 2024, 6: 100504. PMID: 39305900, DOI: 10.1016/j.medj.2024.08.003.Peer-Reviewed Original ResearchOsteoporosis and Primary Biliary Cholangitis: A Trans-ethnic Mendelian Randomization Analysis
Wu Y, Qian Q, Liu Q, Wang R, Pu X, Li Y, Zhang H, You Z, Miao Q, Xiao X, Lian M, Wang Q, Nakamura M, Gershwin M, Li Z, Ma X, Tang R. Osteoporosis and Primary Biliary Cholangitis: A Trans-ethnic Mendelian Randomization Analysis. Clinical Reviews In Allergy & Immunology 2024, 66: 138-148. PMID: 38554235, DOI: 10.1007/s12016-024-08986-4.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2023
Itaconate inhibits CD103+ TRM cells and alleviates hepatobiliary injury in mouse models of primary sclerosing cholangitis
Li Y, Li B, Xiao X, Qian Q, Wang R, Lyu Z, Chen R, Cui N, Ou Y, Pu X, Miao Q, Wang Q, Lian M, Gershwin M, Tang R, Ma X, You Z. Itaconate inhibits CD103+ TRM cells and alleviates hepatobiliary injury in mouse models of primary sclerosing cholangitis. Hepatology 2023, 79: 25-38. PMID: 37505225, DOI: 10.1097/hep.0000000000000549.Peer-Reviewed Original Research
2022
Serum Biomarkers for Autoimmune Hepatitis Type 1: the Case for CD48 and a Review of the Literature
. Serum Biomarkers for Autoimmune Hepatitis Type 1: the Case for CD48 and a Review of the Literature. Clinical Reviews In Allergy & Immunology 2022, 63: 342-356. PMID: 35657576, DOI: 10.1007/s12016-022-08935-z.Peer-Reviewed Original Research
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