Thejal Srikumar, MD, MPH
About
Titles
Assistant Professor
Assistant Program Director, Hematology/Oncology Fellowship Program
Biography
Dr. Srikumar is an Assistant Professor of Medicine (Medical Oncology) and cares for patients as part of the Center for Gastrointestinal Cancers at Smilow Cancer Hospital and Yale Cancer Center in New Haven as well as the Smilow Cancer Genetics and Prevention Program. After obtaining her undergraduate degree from Harvard, Dr. Srikumar received her medical degree from the University of South Florida Morsani College of Medicine, and completed her residency at Yale where she also served as Chief Resident. She then went on to complete her fellowship and served as Chief Fellow in Hematology/Oncology at Yale, during which she obtained an Executive Master of Public Health degree in Epidemiology and Health Informatics tracks.
Dr. Srikumar’s clinical and research efforts center around caring for young adults with gastrointestinal malignancies and patients found to be at high risk for developing gastrointestinal cancers due to certain genetic mutations. She is also passionate about medical education, and serves as an Assistant Program Director of the Yale Medical Oncology-Hematology Fellowship Program.
Appointments
Departments & Organizations
Education & Training
- Fellow, Hematology/Oncology Program
- Yale New Haven Hospital
- Chief Fellow, Hematology/Oncology Program
- Yale New Haven Hospital
- MPH
- Yale School of Public Health , Epidemiology, Health Informatics
- Chief Resident, Traditional Internal Medicine Program
- Yale New Haven Hospital
- Resident, Traditional Internal Medicine Program
- Yale New Haven Hospital
- MD
- University of South Florida Morsani College of Medicine
- AB
- Harvard University, Molecular and Cellular Biology
Research
Research at a Glance
Yale Co-Authors
Publications Timeline
Alfred Lee, MD, PhD
Nikolai Podoltsev, MD, PhD
Tara Sanft, MD
Publications
2024
Longitudinal Curriculum to Address Wellness and Professional Development in a Hematology/Oncology Fellowship Program
Srikumar T, Stempel J, Goldberg S, Podoltsev N, Braun D, Lee A, Sanft T. Longitudinal Curriculum to Address Wellness and Professional Development in a Hematology/Oncology Fellowship Program. EMJ Oncology 2024, 1: 37-39. DOI: 10.33590/oncolamj/zgwb5064.Peer-Reviewed Original ResearchLongitudinal curriculum to address wellness and professional development in a hematology/oncology fellowship program.
Srikumar T, Stempel J, Goldberg S, Podoltsev N, Braun D, Lee A, Sanft T. Longitudinal curriculum to address wellness and professional development in a hematology/oncology fellowship program. Journal Of Clinical Oncology 2024, 42: 9004-9004. DOI: 10.1200/jco.2024.42.16_suppl.9004.Peer-Reviewed Original ResearchConceptsNeeds assessmentLongitudinal curriculumPatient Health Questionnaire 2Score of self-efficacyGeneral Self-Efficacy ScaleFellowship programsBaseline needs assessmentFaculty-led sessionsProfessional boundary settingSelf-Efficacy ScaleLevels of depressionProfessional developmentFirst-year fellowsDidactic sessionsPrevent burnoutChi-square testAcademic yearDebriefing sessionsQuestionnaire 2Baseline assessmentSelf-efficacyProfessional development skillsDepressed moodLeadership skillsBurnout
2019
Semiautomated Measure of Abdominal Adiposity Using Computed Tomography Scan Analysis
Srikumar T, Siegel E, Gu Y, Balagurunathan Y, Garcia A, Chen Y, Zhou J, Zhao X, Gillies R, Clark W, Gamenthaler A, Choi J, Shibata D. Semiautomated Measure of Abdominal Adiposity Using Computed Tomography Scan Analysis. Journal Of Surgical Research 2019, 237: 12-21. PMID: 30694786, PMCID: PMC7771581, DOI: 10.1016/j.jss.2018.11.027.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsVisceral fat areaSubcutaneous fat areaTotal fat areaFat areaTomography scan analysisAbdominal adiposityIntraclass correlationL4-L5 intervertebral levelAverage body mass indexSubcutaneous fat ratioBody mass indexMedian ageRectal adenocarcinomaRisk stratificationMass indexIntervertebral levelObesity epidemicRadiologic methodsAdipose tissueSemiautomated measureAdiposityFat ratioHuman pathophysiologyImaging suiteSemiautomated method
2017
Quantitative Assessment of Visceral Obesity and Postoperative Colon Cancer Outcomes
Ozoya O, Siegel E, Srikumar T, Bloomer A, DeRenzis A, Shibata D. Quantitative Assessment of Visceral Obesity and Postoperative Colon Cancer Outcomes. Journal Of Gastrointestinal Surgery 2017, 21: 534-542. PMID: 28101721, PMCID: PMC5560865, DOI: 10.1007/s11605-017-3362-9.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsBody mass indexVisceral obesityPostoperative morbidityObese patientsShort-term postoperative outcomesOverall complication rateColon cancer outcomesMeasures of adiposityColon cancer patientsMetabolic comorbiditiesPostoperative complicationsComplication ratePostoperative outcomesVisceral adipositySurgical morbidityMass indexRisk stratificationRetrospective studyCancer outcomesCancer patientsTomography assessmentPreoperative CTMortality rateStage IColon cancerAspergillus Terreus Brain Abscess Complicated by Tension Pneumocephalus in a Patient with Angiosarcoma
Srikumar T, Pabbathi S, Fernandez J, Nanjappa S. Aspergillus Terreus Brain Abscess Complicated by Tension Pneumocephalus in a Patient with Angiosarcoma. American Journal Of Case Reports 2017, 18: 33-37. PMID: 28070116, PMCID: PMC5240880, DOI: 10.12659/ajcr.900425.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsMeSH KeywordsAgedAnti-Bacterial AgentsAspergillosisAspergillusBacteremiaBrain AbscessCefepimeCephalosporinsDisease ProgressionDrug CombinationsDrug Therapy, CombinationGlucocorticoidsHemangiosarcomaHumansImmunocompromised HostMagnetic Resonance ImagingMalePneumocephalusProteus mirabilisSkin NeoplasmsStaphylococcus aureusSulfamethizoleTomography, X-Ray ComputedTreatment OutcomeTrimethoprimVancomycinVoriconazoleConceptsTension pneumocephalusComputed tomographyRight frontal lobe abscessCultures of lesionsFrontal lobe abscessLeft arm strengthLow-grade feverProteus mirabilis bacteremiaTrimethroprim/sulfamethoxazoleContinuous supplemental oxygenSystemic antifungal agentsSerial X-raysUpper extremity strengthIntravenous vancomycinRecurrent angiosarcomaBrain abscessesConservative managementEmergent evaluationPrompt diagnosisScalp angiosarcomaSupplemental oxygenIntracranial abscessPoor outcomeCase reportMental status
2016
Potential Use of Flavopiridol in Treatment of Chronic Diseases
Srikumar T, Padmanabhan J. Potential Use of Flavopiridol in Treatment of Chronic Diseases. Advances In Experimental Medicine And Biology 2016, 929: 209-228. PMID: 27771926, DOI: 10.1007/978-3-319-41342-6_9.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsMeSH KeywordsAnimalsAnti-Inflammatory AgentsAntineoplastic Agents, PhytogenicAntiviral AgentsApoptosisCardiovascular AgentsCell Cycle CheckpointsCell ProliferationChronic DiseaseDisease Models, AnimalDrug DiscoveryFlavonoidsHumansMolecular StructurePhytotherapyPiperidinesPlants, MedicinalSignal TransductionConceptsChronic diseasesElicit anti-inflammatory activityAberrant cell cycle activationNFκB-dependent signalingEffect of flavopiridolAnti-inflammatory activityArrests cell cycle progressionCell cycle activationInflammatory stimuliAnti-apoptotic genesAnti-proliferative activityCell cycle progressionDiseaseInhibits expressionCycle activationFlavopiridolCycle progressionCDK inhibitorsPotential useGrowth-arrested cellsRecent studiesRNA polymerase II activationTreatmentP-TEFb complexActivationIncreased incidence of FBXW7 and POLE proofreading domain mutations in young adult colorectal cancers
Kothari N, Teer J, Abbott A, Srikumar T, Zhang Y, Yoder S, Brohl A, Kim R, Reed D, Shibata D. Increased incidence of FBXW7 and POLE proofreading domain mutations in young adult colorectal cancers. Cancer 2016, 122: 2828-2835. PMID: 27244218, PMCID: PMC5014625, DOI: 10.1002/cncr.30082.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsColorectal cancerYounger patientsExome sequencingOutcomes of patientsSporadic colorectal cancerUnique genetic alterationsFisher's exact testCRC data setsWhole-exome sequencingWorse survivalRetrospective studyTreatment modalitiesBRAF mutationsPatientsExact testFBXW7 geneLarger studyOlder agePatient samplesCohortFinal analysisSporadic cancersStatistical significanceGenetic alterationsFuture screeningPortal Hypertension Over the Last 25 Years: Where Did It Go?
Rosemurgy A, Raitano O, Srikumar T, Sawangkum P, Luberice K, Ryan C, Ross S. Portal Hypertension Over the Last 25 Years: Where Did It Go? Journal Of The American College Of Surgeons 2016, 222: 1164-1170. PMID: 27234633, DOI: 10.1016/j.jamcollsurg.2016.02.017.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsPercentage of patientsPortal hypertensionDecompressive shuntsHospital mortalityEndoscopic therapyEndoscopic treatmentNumber of patientsEsophageal varicesHealth care administrationHospital inpatientsHypertensionPatientsShuntDiagnosisCare administrationVaricesSurgeryTherapyMortalityTreatmentAdmissionInpatientsYearsSurgeonsAdministrationSynchronous rectal adenocarcinoma and splenic marginal zone lymphoma
Srikumar T, Markow M, Centeno B, Hoffe S, Tao J, Fernandez H, Strosberg J, Shibata D. Synchronous rectal adenocarcinoma and splenic marginal zone lymphoma. Current Oncology 2016, 23: 70-74. PMID: 26966416, PMCID: PMC4754072, DOI: 10.3747/co.23.2711.Peer-Reviewed Original ResearchCitationsConceptsMarginal zone lymphomaSplenic marginal zone lymphomaRectal adenocarcinomaMassive splenomegalyExternal beam radiation therapyAdjuvant FOLFOX chemotherapyDifferent primary originsEn bloc splenectomySynchronous rectal adenocarcinomaLow anterior resectionAdvanced rectal cancerBone marrow biopsyComplete blood countComputed tomography (CT) imagingFOLFOX chemotherapyPelvic radiationStage T3N1M0Abdominal painAnterior resectionDistal pancreatectomySynchronous cancersConcomitant diagnosisRectal cancerClinical presentationMarrow biopsy
2015
Genetic analysis of colorectal cancers in young patients.
Abbott A, Kothari N, Teer J, Srikumar T, Kim R, Reed D, Shibata D. Genetic analysis of colorectal cancers in young patients. Journal Of Clinical Oncology 2015, 33: 632-632. DOI: 10.1200/jco.2015.33.3_suppl.632.Peer-Reviewed Original ResearchConceptsColorectal cancerYounger patientsExact testUnique molecular changesYoung CRC patientsFisher's exact testTargeted exome sequencingCRC patientsOlder patientsMedian ageWorse prognosisCRC casesTreatment strategiesHereditary syndromesHereditary cancer genesPatientsMutation frequencyNormal variantsExome sequencingGenetic alterationsDifferential mutation frequenciesGenetic conditionsMolecular changesOlder cohortSomatic mutations
Clinical Care
Overview
Clinical Specialties
Board Certifications
Internal Medicine
- Certification Organization
- AB of Internal Medicine
- Original Certification Date
- 2020
Are You a Patient?
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News
- August 29, 2024
Dr. Thejal Srikumar Joins Center for Gastrointestinal Cancers at Smilow Cancer Hospital and Yale Cancer Center
- August 14, 2024
Welcome New Staff, Faculty, Fellows, Postgrads & Postdocs (August 2024)
- June 07, 2024
Yale Cancer Center Researchers and Trainees Present at ASCO
- June 01, 2024
Accolades, Awards & Honors